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您的检索式：作者名="Youshun Lin"
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| 1 | MYB106 is a negative regulator and a substrate for CRL3^(BPM) E3 ligase in regulating flowering time in Arabidopsis thaliana显示文摘Flowering time is crucial for successful reproduction in plants, the onset and progression of which are strictly controlled. However, flowering time is a complex and environmentally responsive history trait and the underlying mechanisms still need to be fully characterized. Post-translational regulation of the activities of transcription factors(TFs) is a dynamic and essential mechanism for plant growth and development. CRL3 BPME3 ligase is a CULLIN3-based E3 ligase involved in orchestrating protein stability via the ubiquitin proteasome pathway. Our study shows that the mutation of MYB106 induced early flowering phenotype while over-expression of MYB106 delayed Arabidopsis flowering. Transcriptome analysis of myb106 mutants reveals 257 differentially expressed genes between wild type and myb106-1 mutants, including Flowering Locus T(FT) which is related to flowering time. Moreover, in vitro electrophoretic mobility shift assays(EMSA), in vivo chromatin immunoprecipitation quantitative polymerase chain reaction(ChIP-q PCR) assays and dual luciferase assays demonstrate that MYB106 directly binds to the promoter of FT to suppress its expression. Furthermore, we confirm that MYB106 interacts with BPM proteins which are further identified by CRL3 BPME3 ligases as the substrate. Taken together, we have identified MYB106 as a negative regulator in the control of flowering time and a new substrate for CRL3 BPM E3 ligases in Arabidopsis. | Liu Hong Fangfang Niu Youshun Lin Shuang Wang Liyuan Chen Liwen Jiang | 2021 | Journal of Integrative Plant Biology2021，63，6： | 3 |
| 2 | AtBRO1 Functions in ESCRT-Ⅰ Complex to Regulate Multivesicular Body Protein Sorting显示文摘 | Jinbo Shen Caiji Gao Qiong Zhao Youshun Lin Xiangfeng Wang Xiaohong Zhuang Liwen Jiang | 2016 | Molecular Plant2016，9，5： | 2 |
| 3 | Plant Rho GTPase signaling promotes autophagy显示文摘The roles of Rho family guanosine triphosphatases(GTPases)of plants(ROPs)in modulating plant growth and development have been well characterized.However,little is known about the roles of ROP signaling pathways in regulating plant autophagy and autophagosome formation.In this study,we identify a unique ROP signaling mechanism,which mediates developmental to autophagic transition under stress conditions in the model plant Arabidopsis.Loss-of-function mutants of ROP8 showed stress-induced hypersensitive phenotypes and compromised autophagic flux.Similar to other ROPs in the ROP/RAC family,ROP8 exhibits both plasma membrane and cytosolic punctate localization patterns.Upon autophagic induction,active ROP8 puncta colocalize with autophagosomal markers and are degraded inside the vacuole.In human cells,RalB,an RAS subfamily GTPase,engages its effector Exo84 for autophagosome assembly.However,a RalB counterpart is missing in the plant lineage.Intriguingly,we discovered that plant ROP8 promotes autophagy via its downstream effector Sec5.Live-cell super-resolution imaging showed that ROP8 and Sec5 reside on phagophores for autophagosome formation.Taken together,our findings highlight a previously unappreciated role of an ROP8-Sec5 signaling axis in autophagy promotion,providing new insights into how plants utilize versatile ROP signaling networks to coordinate developmental and autophagic responses depending on environmental changes. | Youshun Lin Yonglun Zeng Ying Zhu Jinbo Shen Hao Ye Liwen Jiang | 2021 | Molecular Plant2021，14，6： | 0 |
| 4 | The molecular basis of heat stress responses in plants显示文摘Global warming impacts crop production and threatens food security.Elevated temperatures are sensed by different cell components.Temperature increases are classified as either mild warm temperatures or excessively hot temperatures,which are perceived by distinct signaling pathways in plants.Warm temperatures induce thermomorphogenesis,while high-temperature stress triggers heat acclimation and has destructive effects on plant growth and development.In this review,we systematically summarize the heat-responsive genetic networks in Arabidopsis and crop plants based on recent studies.In addition,we highlight the strategies used to improve grain yield under heat stress from a source-sink perspective.We also discuss the remaining issues regarding the characteristics of thermosensors and the urgency required to explore the basis of acclimation under multifactorial stress combination. | Yi Kan Xiao-Rui Mu Jin Gao Hong-Xuan Lin Youshun Lin | 2023 | Molecular Plant2023，16，10： | 0 |
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