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| 1 | Arctic Sea Ice and Eurasian Climate:A Review显示文摘The Arctic plays a fundamental role in the climate system and has shown significant climate change in recent decades,including the Arctic warming and decline of Arctic sea-ice extent and thickness. In contrast to the Arctic warming and reduction of Arctic sea ice, Europe, East Asia and North America have experienced anomalously cold conditions, with record snowfall during recent years. In this paper, we review current understanding of the sea-ice impacts on the Eurasian climate.Paleo, observational and modelling studies are covered to summarize several major themes, including: the variability of Arctic sea ice and its controls; the likely causes and apparent impacts of the Arctic sea-ice decline during the satellite era,as well as past and projected future impacts and trends; the links and feedback mechanisms between the Arctic sea ice and the Arctic Oscillation/North Atlantic Oscillation, the recent Eurasian cooling, winter atmospheric circulation, summer precipitation in East Asia, spring snowfall over Eurasia, East Asian winter monsoon, and midlatitude extreme weather; and the remote climate response(e.g., atmospheric circulation, air temperature) to changes in Arctic sea ice. We conclude with a brief summary and suggestions for future research. | GAO Yongqi SUN Jianqi LI Fei HE Shengping Stein SANDVEN YAN Qing ZHANG Zhongshi Katja LOHMANN Noel KEENLYSIDE Tore FUREVIK SUO Lingling | 2015 | Advances in Atmospheric Sciences2015，32，1： | 21 |
| 2 | Ground settlement of Chek Lap Kok Airport,Hong Kong,detected by satellite synthetic aperture radar interferometry显示文摘Satellite synthetic aperture radar (SAR) inter-ferometry is used to investigate the slowly accumulating ground settlement at the new Chek Lap Kok Airport in Hong Kong. Most of the land occupied by the airport was reclaimed from the sea and therefore certain ground settlement in the area has been expected. A pair of ERS-2 SAR images spanning nearly a year is used in the study. The high spatial resolution (20 m×20 m) ground settlement map derived indicates that the settlement that occurred in the area over the time period is as large as 50 mm. The SAR measurement results agree with the levelling measurements at some benchmarks in the area to well within 1 cm(rms error),and the overall correlation between the two types of results is 0.89. The paper presents some brief background of inter-ferometric SAR, and outlines the data processing methods and results. | LIU Guoxiang DING Xiaoli CHEN Yongqi LI Zhilin LI Zhiwei | 2001 | Chinese Science Bulletin2001，46，21： | 16 |
| 3 | Neuroprotective effects of Ginkgo biloba extract and GinkgoUde B against oxygen-glucose deprivation/reoxygenation and glucose injury in a new in vitro multicellular network model显示文摘 | Xiaohan Yang Tiezheng Zheng Hao Hong Nan Cai Xiaofeng Zhou Changkai Sun Liying Wu Shuhong Liu Yongqi Zhao Lingling Zhu Ming Fan Xuezhong Zhou Fengxie Jin | 2018 | Frontiers of Medicine2018，12，3： | 12 |
| 4 | Overexpression of the tonoplast aquaporin AtTIP5;1 conferred tolerance to boron toxicity in Arabidopsis显示文摘Boron (B) toxicity to plants is responsible for low crop productivity in many regions of the world. Here we report a novel and effective means to alleviate the B toxicity to plants under high B circumstance. Functional characterization of AtTIP5;1, an aquaporin gene, re-vealed that overexpression of AtTIP5;1 (OxAtTIP5;1) in Arabidopsis significantly increased its tolerance to high B toxicity. Compared to wild-type plants, OxAtTIP5;1 plants exhibited longer hypocotyls, accelerated development, increased silique production under high B treatments. GUS staining and quantitative RT-PCR (qRT-PCR) results demonstrated that the expression of AtTIP5;1 was induced by high B concentration treatment. Subcellular localization analysis revealed that the AtTIP5;1-GFP fusion protein was localized on the tonoplast membrane, which was consistent with the prediction based on bioinformatics. Taken together, our results suggest that AtTIP5;1 is in-volved in B transport pathway possibly via vacuolar compartmentation for B, and that overexpression of AtTIP5;1 in plants may provide an effective way to overcome the problem resulting from high B concentration toxicity. | Yongqi Pang, Lijuan Li, Fei Ren, Pingli Lu, Pengcheng Wei, Jinghui Cai, Lingguo Xin, Juan Zhang, Jia Chen, Xuechen Wang State Key Laboratory of Plant Physiology and Biochemistry, College of Biological Sciences, China Agricultural University, Beijing 100193, China | 2010 | Journal of Genetics and Genomics2010，37，6： | 11 |
| 5 | The responses of East Asian Summer monsoon to the North Atlantic Meridional Overturning Circulation in an enhanced freshwater input simulation显示文摘We investigated the response of the East Asian Summer Monsoon (EASM) to a weakened Atlantic Meridional Overturning Circulation (AMOC) and its mechanism in an enhanced freshwater input experiment (FW) by using a fully-coupled climate model. The response was a weakened EASM and the mechanisms can be explained as follows. The simulated weakened AMOC resulted in a drop in sea surface temperature (SST) in the North Atlantic (NA) and, correspondingly, an anomalous high sea level pressure (SLP) over the North American regions, which in turn increased the northeast surface winds across the equator in the eastern tropical Pacific (ETP). The anomalous northeast winds then induced further upwelling in the ETP and stronger air/sea heat exchange, therefore leading to an anomalous cooling of the eastern tropical sea surface. As a result, the climatologic Hadley Circulation (HC) was weakened due to an anomalous stronger sinking of air in the ETP north of the equator, whereas the Walker Circulation (WC) in the western tropical Pacific (WTP) north of the equator was strengthened with an eastward-shifted upwelling branch. This feature was in agreement with the anomalous convergent winds in the WTP, and led to a weakened EASM and less East Asian summer precipitation (EASP). Furthermore, comparison with previous freshwater experiments indicates that the strength of EASP could be influenced by the magnitude of the added freshwater. | YU Lei GAO YongQi WANG HuiJun GUO Dong LI ShuangLin | 2009 | Chinese Science Bulletin2009，54，24： | 11 |
| 6 | WIP1 Phosphatase Plays a Critical Neuroprotective Role in Brain Injury Induced by High-Altitude Hypoxic Inflammation显示文摘The hypobaric hypoxic environment in highaltitude areas often aggravates the severity of inflammation and induces brain injury as a consequence. However, the critical genes regulating this process remain largely unknown. The phosphatase wild-type p53-induced phosphatase 1(WIP1) plays important roles in various physiological and pathological processes, including the regulation of inflammation in normoxia, but its functions in hypoxic inflammation-induced brain injury remain unclear.Here, we established a mouse model of this type of injury and found that WIP1 deficiency augmented the release of inflammatory cytokines in the peripheral circulation and brain tissue, increased the numbers of activated microglia/macrophages in the brain, aggravated cerebral histological lesions, and exacerbated the impairment of motor and cognitive abilities. Collectively, these results provide the first in vivo evidence that WIP1 is a critical neuroprotector against hypoxic inflammation-induced brain injury. | Dahu Li Lijun Zhang Xin Huang Lili Liu Yunling He Lun Xu Yiyao Zhang Tong Zhao Liying Wu Yongqi Zhao Kuiwu Wu Yan Wu Ming Fan Lingling Zhu | 2017 | Neuroscience Bulletin2017，33，3： | 9 |
| 7 | Teleconnection between Sea Ice in the Barents Sea in June and the Silk Road,Pacific–Japan and East Asian Rainfall Patterns in August显示文摘In contrast to previous studies that have tended to focus on the influence of the total Arctic sea-ice cover on the East Asian summer tripole rainfall pattern, the present study identifies the Barents Sea as the key region where the June sea-ice variability exerts the most significant impacts on the East Asian August tripole rainfall pattern, and explores the teleconnection mechanisms involved. The results reveal that a reduction in June sea ice excites anomalous upward air motion due to strong near-surface thermal forcing, which further triggers a meridional overturning wave-like pattern extending to midlatitudes.Anomalous downward motion therefore forms over the Caspian Sea, which in turn induces zonally oriented overturning circulation along the subtropical jet stream, exhibiting the east–west Rossby wave train known as the Silk Road pattern. It is suggested that the Bonin high, a subtropical anticyclone predominant near South Korea, shows a significant anomaly due to the eastward extension of the Silk Road pattern to East Asia. As a possible descending branch of the Hadley cell, the Bonin high anomaly ultimately triggers a meridional overturning, establishing the Pacific–Japan pattern. This in turn induces an anomalous anticyclone and cyclone pair over East Asia, and a tripole vertical convection anomaly meridionally oriented over East Asia. Consequently, a tripole rainfall anomaly pattern is observed over East Asia. Results from numerical experiments using version 5 of the Community Atmosphere Model support the interpretation of this chain of events. | Shengping HE Yongqi GAO Tore FUREVIK Huijun WANG Fei LI | 2018 | Advances in Atmospheric Sciences2018，35，1： | 9 |
| 8 | OTOTOXIC MODEL OF OXALIPLATIN AND PROTECTION FROM NICOTINAMIDE ADENINE DINUCLEOTIDE显示文摘Oxaliplatin,an anticancer drug commonly used to treat colorectal cancer and other tumors,has a number of serious side effects,most notably neuropathy and ototoxicity.To gain insights into its ototoxic profile,oxaliplatin was applied to rat cochlear organ cultures.Consistent with it neurotoxic propensity,oxaliplatin selectively damaged nerve fibers at a very low dose 1μM.In contrast,the dose required to damage hair cells and spiral ganglion neurons was 50 fold higher(50μM).Oxailiplatin-induced cochlear lesions initially increased with dose,but unexpectedly decreased at very high doses.This non-linear dose response could be related to depressed oxaliplatin uptake via active transport mechanisms.Previous studies have demonstrated that axonal degeneration involves biologically active processes which can be greatly attenuated by nicotinamide adenine dinucleotide(NAD+).To determine if NAD+would protect spiral ganglion axons and the hair cells from oxaliplatin damage,cochlear cultures were treated with oxaliplatin alone at doses of 10μM or 50μM respectively as controls or combined with 20 mM NAD+.Treatment with 10μM oxaliplatin for 48 hours resulted in minor damage to auditory nerve fibers,but spared cochlear hair cells.However,when cochlear cultures were treated with 10μM oxaliplatin plus 20 mM NAD+,most auditory nerve fibers were intact.50μM oxaliplatin destroyed most of spiral ganglion neurons and cochlear hair cells with apoptotic characteristics of cell fragmentations.However,50μM oxaliplatin plus 20 mM NAD+treatment greatly reduced neuronal degenerations and hair cell missing.The results suggested that NAD+provides significant protection against oxaliplatin-induced neurotoxicity and ototoxicity,which may be due to its actions of antioxidant,antiapoptosis,and energy supply. | DING Dalian JIANG Haiyan FU Yong LI Yongqi Richard Salvi Shinichi Someya Masaru Tanokura | 2013 | Journal of Otology2013，8，1： | 9 |
| 9 | Formaldehyde induces toxic effects and regulates the expression of damage response genes in BM-MSCs显示文摘在这研究,我们在老鼠骨头髓上估计了甲醛(FA ) 的有毒的效果间充质的干细胞(BM-MSCs ) 。Cytotoxicity 被使用 MTT 试金测量。DNA 海滨破裂被与朊酶 K (PK ) 修改的标准碱的彗星试金和彗星试金检测。DNAprotein 交叉连接(DPC ) 被 KCl-SDS 降水试金检测。我们发现在从 75 ~ 200 M 的集中的 FA 禁止了房间幸存并且在 125 M 上导致了 DPC。修改 PK 的彗星试金证明那导致 FA 的 DNA 海滨破裂从 75 ~ 200 M 以一种剂量依赖者方式被增加。在另一方面,标准碱的彗星试金证明那 DNA 海滨破裂在 125 M 上与 FA 集中被减少。我们由使用在 DPC 和幸存率之间有否定线性关联的皮尔森关联证实了(r = 0.987, P < 0.01 ) 并且在 DPC 和(i) 姐妹染色单体交换之间的积极线性关系并且(ii ) micronucleus (r = 0.995, P < 0.01;r = 0.968, P < 0.01 ) 。DNA 损坏 RT2 剖析程序聚合酶链反应数组被用来在损坏反应基因的表达式调查变化。相应再结合小径的核苷酸切除修理小径和 Brca2, Rad51,和 Xrcc2 的 Xpa 和 Xpc 都在 75 和 125 M FA 是起来调整的。然而,一样的基因与 175 M FA 是下面调整的。Chek1 和 Hus1 的表情,涉及房间周期规定,与 75, 125,和 175 M FA 以一样的方式被改变。这些结果显示 Xpa, Xpc, Brca2, Rad51, Xrcc2, Chek1,和 Hus1 是必要的让 BM-MSCs 抵抗 FA 的效果。 | Yali She Yi Li Yongqi Liu Guli Asai Shaobo Sun Jianxin He Zheng Pan Yan Cui | 2013 | Acta Biochimica et Biophysica Sinica2013，45，12： | 8 |
| 10 | A High-Resolution Earth’s Gravity Field Model SGG-UGM-2 from GOCE,GRACE,Satellite Altimetry,and EGM2008显示文摘This paper focuses on estimating a new high-resolution Earth’s gravity field model named SGG-UGM-2 from satellite gravimetry,satellite altimetry,and Earth Gravitational Model 2008(EGM2008)-derived gravity data based on the theory of the ellipsoidal harmonic analysis and coefficient transformation(EHA-CT).We first derive the related formulas of the EHA-CT method,which is used for computing the spherical harmonic coefficients from grid area-mean and point gravity anomalies on the ellipsoid.The derived formulas are successfully evaluated based on numerical experiments.Then,based on the derived least-squares formulas of the EHA-CT method,we develop the new model SGG-UGM-2 up to degree 2190 and order 2159 by combining the observations of the Gravity Field and Steady-State Ocean Circulation Explorer(GOCE),the normal equation of the Gravity Recovery and Climate Experiment(GRACE),marine gravity data derived from satellite altimetry data,and EGM2008-derived continental gravity data.The coefficients of degrees 251–2159 are estimated by solving the block-diagonal form normal equations of surface gravity anomalies(including the marine gravity data).The coefficients of degrees 2–250 are determined by combining the normal equations of satellite observations and surface gravity anomalies.The variance component estimation technique is used to estimate the relative weights of different observations.Finally,global positioning system(GPS)/leveling data in the mainland of China and the United States are used to validate SGG-UGM-2 together with other models,such as European improved gravity model of the earth by new techniques(EIGEN)-6C4,GECO,EGM2008,and SGG-UGM-1(the predecessor of SGG-UGM-2).Compared to other models,the model SGG-UGM-2 shows a promising performance in the GPS/leveling validation.All GOCE-related models have similar performances both in the mainland of China and the United States,and better performances than that of EGM2008 in the mainland of China.Due to the contribution of GRACE data and the new marine gravity anomalies,SGG-UGM-2 is slightly better than SGG-UGM-1 both in the mainland of China and the United States. | Wei Liang Jiancheng Li Xinyu Xu Shengjun Zhang Yongqi Zhao | 2020 | Engineering2020，6，8： | 8 |
| 11 | Extracts from Huangqi(Radix Astragali Mongoliciplus) and Ezhu(Rhizoma Curcumae Phaeocaulis) inhibit Lewis lung carcinoma cell growth in a xenograft mouse model by impairing mitogen-activated protein kinase signaling, vascular endothelial growth factor prod显示文摘OBJECTIVE: To study the anti-tumor effects of the extracts from Huangqi(Radix Astragali Mongolici)and Ezhu(Rhizoma Curcumae Phaeocaulis) on the growth of Lewis lung carcinoma(LLC) in a xenograft mouse model and to investigate the possible underlying mechanism.METHODS: LLC tumor-bearing C57 BL/6 mice were treated with normal saline, cisplatin(2 mg/kg intraperitoneally every other day), or Huangqi(Radix Astragali Mongolici) and Ezhu(Rhizoma Curcumae Phaeocaulis)(1∶1, 2∶1, or 3∶1 ratio;5, 8, or 11 g/kg crude drug intragastrically every day) for 15 d.Body weights and tumor volumes were measured every other day. Tumors were excised on day 15 and analyzed. Tumor microvessel density(MVD)was assessed by immunohistochemical staining of CD34;and expression of vascular endothelial cell growth factor(VEGF), the mitogen-activated protein kinases p38 mitogen-activated protein kinase(MAPK), extracellular signal-regulated kinases 1 and 2(ERK1/2), and Jun N-terminal kinase(JNK)and their phosphorylated forms were assessed by Western blotting.RESULTS: Treatment with cisplatin caused a significant loss of body weight compared with controls,whereas Huangqi(Radix Astragali Mongolici) and Ezhu(Rhizoma Curcumae Phaeocaulis) extract combinations had no effect. Extracts from Huangqi(Radix Astragali Mongolici) and Ezhu(Rhizoma Curcumae Phaeocaulis) significantly decreased tumor weight and tumor MVD compared with controls,and at the 3∶1 treatment group had similar efficacy to cisplatin in reducing MVD. Tumors from Huangqi(Radix Astragali Mongolici) and Ezhu(Rhizoma Curcumae Phaeocaulis) treatments also showed decreased p38 MAPK, p-p38 MAPK, ERK1/2, p-ERK1/2,JNK, and p-JNK expression compared with the control group(all P < 0.01). VEGF protein expression was significantly reduced in the 2∶1 and 3∶1 treatment groups compared with the control group(P < 0.01).CONCLUSION: Extracts from Huangqi(Radix Astragali Mongolici) and Ezhu(Rhizoma Curcumae Phaeocaulis) hindered LLC growth in the xenograft mouse model, possibly via inhibition of the MAPK signaling pathway, VEGF production, and tumor angiogenesis. | Xu Chengyong Wang Yuguo Feng Jian Xu Ran Dou Yongqi | 2019 | Journal of Traditional Chinese Medicine2019，39，4： | 7 |
| 12 | Open-circuit Fault Diagnosis of Traction Inverter Based on Compressed Sensing Theory显示文摘This study proposes a new method of fault diagnosis based on the least squares support vector machine with gradient information(G-LS-SVM)to solve the insulated-gate bipolar transistor(IGBT)open-circuit failure problem of the traction inverter in a catenary power supply system.First,a simulation model based on traction inverter topology is built,and various voltage fault signal waveforms are simulated based on the IGBT inverter open-circuit fault classification.Second,compressive sensing theory is used to sparsely represent the voltage fault signal and make it a fault signal.The new method has a high degree of sparseness and builds an overcomplete dictionary model containing the feature vectors of voltage fault signals based on a double sparse dictionary model to match the sparse signal characteristics.Finally,the space vector transform is used to represent the three-phase voltage scalar in the traction inverter as a composite quantity to reduce the redundancy of the fault signals and data-processing capabilities.A G-LS-SVM fault diagnosis model is then built to diagnose and identify the voltage fault signal feature vector in an overcomplete dictionary.The simulation results show that the accuracy of this method for various types of IGBT tube fault diagnosis is over 98.92%.Moreover,the G-LS-SVM model is robust and not affected by Gaussian white noise. | Yongqi Cheng Weiguang Dong Fengyang Gao Guoqing Xin | 2020 | Chinese Journal of Electrical Engineering2020，6，1： | 6 |
| 13 | The spatial pattern of grassland aboveground biomass on Xizang Plateau and its climatic controls显示文摘Aims Grassland is the most widely distributed vegetation type on the Xizang Plateau.Accurate remote sensing estimation of the grass-land aboveground biomass(AGB)in this region is influenced by the types of vegetation indexes(VIs)used,the grain size(resolution)of the remote sensing data and the targeted ecosystem features.This study attempts to answer the following questions:(i)Which VI can most accurately reflect the grassland AGB distribution on the Xizang Plateau?(ii)How does the grain size of remote sensing imagery affect AGB reflection?(iii)What is the spatial distribution pattern of the grassland AGB on the plateau and its relationship with the climate?Methods We investigated 90 sample sites and measured site-specific AGBs using the harvest method for three grassland types(alpine meadow,alpine steppe and desert steppe).For each sample site,four VIs,namely,Normalized Difference VI(NDVI),Enhanced VI,Normalized Difference Water Index(NDWI)and Modified Soil-Adjusted VI(MSAVI)were extracted from the Moderate Resolution Imaging Spectroradiometer(MODIS)products with grain sizes of 250 m and 1 km.Linear regression models were employed to iden-tify the best estimator of the AGB for the entire grassland and the three individual grassland types.Paired Wilcoxon tests were applied to assess the grain size effect on the AGB estimation.General linear models were used to quantify the relationships between the spatial distribution of the grassland AGB and climatic factors.Important Findings The results showed that the best estimator for the entire grass-land AGB on the Xizang Plateau was MSAVI at a 250 m grain size(MSAVI_(250 m)).For each individual grassland type,the best estimator was MSAVI at a grain size of 250 m for alpine meadow,NDWI at a grain size of 1 km for alpine steppe and NDVI at a grain size of 1 km for desert steppe.The explanation ability of each VI for the grassland AGB did not significantly differ for the two grain sizes.Based on the best fit model(AGB=−10.80+139.13 MSAVI_(250 m)),the spatial pattern of the grassland AGB on the plateau was characterized.The AGB varied from 1 to 136 g m^(−2).Approximately 59%of total spatial variation in the AGB for the entire grassland was explained by the combination of the mean annual precipitation(MAP)and mean annual temperature.The explanatory power of MAP was weaker for each individual grassland type than that for the entire grassland.This study illustrated the high efficiency of the VIs derived from MODIS data in the grassland AGB estimation on the Xizang Plateau due to the vegetation homogeneity within a 1×1 km pixel in this region.Furthermore,MAP is a primary driver on the spatial variation of AGB at a regional scale. | Yanbin Jiang Jian Tao Yongqi Huang Juntao Zhu Li Tian Yangjian Zhang | 2015 | Journal of Plant Ecology2015，8，1： | 6 |
| 14 | Structural vibration passive control and economic analysis of a high-rise building in Beijing显示文摘Performance analysis of the Pangu Plaza under earthquake and wind loads is described in this paper.The plaza is a 39-story steel high-rise building,191 m high,located in Beijing close to the 2008 Olympic main stadium.It has both fluid viscous dampers(FVDs) and buckling restrained braces or unbonded brace(BRB or UBB) installed.A repeated iteration procedure in its design and analysis was adopted for optimization.Results from the seismic response analysis in the horizontal and vertical directions show that the FVDs are highly effective in reducing the response of both the main structure and the secondary system.A comparative analysis of structural seismic performance and economic impact was conducted using traditional methods,i.e.,increased size of steel columns and beams and/or use of an increased number of seismic braces versus using FVD.Both the structural response and economic analysis show that using FVD to absorb seismic energy not only satisfi es the Chinese seismic design code for a 'rare' earthquake,but is also the most economical way to improve seismic performance both for one-time direct investment and long term maintenance. | Chen Yongqi Cao Tiezhu Ma Liangzhe Luo Chaoying | 2009 | Earthquake Engineering and Engineering Vibration2009，8，4： | 6 |
| 15 | Ricin-B-lectin enhances microsporidia Nosema bombycis infection in BmN cells from silkworm Bombyx mori显示文摘 | Han Liu Mingqian Li Shunfeng Cai Xinyi He Yongqi Shao Xingmeng Lu | 2016 | Acta Biochimica et Biophysica Sinica2016，48，11： | 6 |
| 16 | Hydrothermal synthesized porous Co(OH)_2 nanoflake film for supercapacitor application显示文摘Porous Co(OH)2 film directly grown on nickel foam is prepared by a facile hydrothermal method.The as-prepared Co(OH)2 film possesses a structure consisting of randomly porous nanoflakes with thicknesses of 20-30 nm.The capacitive behavior of the Co(OH)2 film is investigated by cyclic voltammograms and galvanostatic charge-discharge tests in 2 mol/L KOH.The porous Co(OH)2 film exhibits a high discharge capacitance of 935 F g-1 at a current density of 2 A g-1 and excellent rate capability.The specific capacitance keeps a capacitance of 589 F g-1 when the current density increases to 40 A g-1.The specific capacitance of 82.6% is maintained after 1500 cycles at 2 A g-1. | ZHANG YongQi XIA XinHui KANG Jing TU JiangPing | 2012 | Chinese Science Bulletin2012，57，32： | 6 |
| 17 | Genome re-sequencing analysis uncovers pathogenecity-related genes undergoing positive selection in Magnaporthe oryzae显示文摘Rice blast caused by Magnaporthe oryzae(M.oryzae) is one of the most destructive diseases,which causes significant rice yield losses and affects global food security.To better understand genetic variations among different isolates of M.oryzae in nature,we re-sequenced the genomes of two field isolates,CH43 and Zhong-10-8-14,which showed distinct pathogenecity on most of the rice cultivars.Genome-wide genetic variation analysis reveals that ZHONG-10-8-14 exhibits higher sequence variations than CH43.Structural variations(SVs) detection shows that the sequence variations primarily occur in exons and intergenic regions.Bioinformatics analysis for gene variations reveals that many pathogenecity-related pathways are enriched.In addition,193 candidate effectors with various DNA polymorphisms were identified,including two known effectors AVR-Pik and AVR-Pital.Comparative polymorphism analysis of thirteen randomly selected effectors suggests that the genetic variations of effectors are under positive selection.The expression pattern analysis of several pathogenecity-related variant genes indicates that these genes are differentially regulated in two isolates,with much higher expression levels in Zhong-10-8-14 than CH43.Our data demonstrate that the genetic variations of effectors and pathogenecity-related genes are under positive selection,resulting in the distinct pathogenicities of CH43 and Zhong-10-8-14 on rice. | Jidong Cao Yongqi Yu Junkai Huang Rui Liu Yan Chen Suiyan Li Jun Liu | 2017 | Science China(Life Sciences)2017，60，8： | 6 |
| 18 | Study on microscope hyperspectral medical imaging method for biomedical quantitative analysis显示文摘A microscopic pushbroom hyperspectral imaging system was developed based on the microscopic technology and spectral imaging technology according to the principle of spectral imager in remote sensing. The basic principle and key technologies of this system were presented and the system per- formance was also analyzed. Some methods and algorithms were proposed to preprocess and nor- malize the microscopic hyperspectral data and retrieve the transmittance spectrum of samples. As a case study, the microscopic hyperspectral imaging system was used to image the retina sections of different rats and get some significant results. Experiment results show that the system can be used for the quantitative assessment and evaluating the effect of medication in biomedical research. | LI QingLi XUE YongQi XIAO GongHai ZHANG JingFa | 2008 | Chinese Science Bulletin2008，53，9： | 5 |
| 19 | Studies on Fatty Acid Composition in the Oil of Momordica cochinchinensis显示文摘对木鳖子油中脂肪酸组成进行分析 ,采用石油醚提取脂肪油 ,快速甲酯化法制备成甲酯衍生物 ,GC- MS联用技术分析其中的脂肪酸组成和相对百分含量 ,鉴定了 8种脂肪酸成分 ,为开发利用木鳖子资源提供了依据。 | Shang Huijuan Yuan Chunfang Wang Yuguang Gao Qipin Wang Wei Niu Zhiduo Wang Yongqi | 2000 | 中草药2000，31，10： | 5 |
| 20 | The Response of the East Asian Summer Monsoon to Strong Tropical Volcanic Eruptions显示文摘A 600-year integration performed with the Bergen Climate Model and National Centers for Environmental Prediction/National Center for Atmospheric Research(NCEP/NCAR) reanalysis data were used to investigate the impact of strong tropical volcanic eruptions on the East Asian summer monsoon(EASM) and EASM rainfall. Both the simulation and NCEP/NCAR reanalysis data show a weakening of the EASM in strong eruption years. The model simulation suggests that North and South China experience droughts and the Yangtze–Huaihe River Valley experiences floods during eruption years. In response to strong tropical volcanic eruptions, the meridional air temperature gradient in the upper troposphere is enhanced, which leads to a southward shift and an increase of the East Asian subtropical westerly jet stream(EASWJ). At the same time, the land–sea thermal contrast between the Asian land mass and Northwest Pacific Ocean is weakened. The southward shift and increase of the EASWJ and reduction of the land–sea thermal contrast all contribute to a weakening of the EASM and EASM rainfall anomaly. | CUI Xuedong GAO Yongqi SUN Jianqi | 2014 | Advances in Atmospheric Sciences2014，31，6： | 5 |
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