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| 1 | USP3 inhibits type I interferon signaling by deubiquitinating RIG-I-like receptors显示文摘(K63 ) 离氨酸 63 连接了 RIG-I 戏的 ubiquitination 在类型的激活的一个关键角色我干扰素小径,然而,为它的 deubiquitination 负责的分子的机制仍然糟糕被理解。这里,我们报导 deubiquitination 酶 ubiquitin 特定的朊酶(USP3 ) 3 否定地调整类型的激活我干扰素由指向 RIG-I 发信号。USP3 击倒 RIG-I 的明确地提高的连接 K63 的 ubiquitination, upregulated IRF3 的 phosphorylation 并且扩充了类型的生产我干扰素 cytokines 和抗病毒的免疫。我们进一步证明在 unstimulated 或 uninfected 房间在 USP3 和 RIG-I-like 受体( RLR )之间没有相互作用,但是在病毒的感染或 ligand 刺激之上, USP3 绑在 RLR 的 caspase 激活招募领域然后通过它的锌手指的合作劈开 polyubiquitin 链Ub有约束力的领域和 USP 催化领域。变化分析表明到 RIG-I 上的 polyubiquitin 链的 USP3 的那绑定是为它 polyubiquitin 链的劈开的前提步。我们的调查结果在 RIG-I 激活识别 USP3 的一个以前未被认出的角色并且提供卓见进 USP3 由禁止 RIG-I 发信号和抗病毒的免疫的机制。 | Jun Cui Yanxia Song Yinyin Li Qingyuan Zhu Peng Tan Yunfei Qin Helen Y Wang Rong-Fu Wang | 2014 | Cell Research2014，24，4： | 20 |
| 2 | Effects of dietary alfalfa flavonoids extraction on growth performance,organ development and blood biochemical indexes of Yangzhou geese aged from 28 to 70 days显示文摘This experiment was conducted to study the effects of dietary alfalfa flavonoids extraction supplemental level on growth performance, organ development and blood biochemical indexes of Yangzhou geese at the age of 28 to 70 days. Two hundred and forty 21-day-old healthy male geese with similar body weight were randomly distributed into 4 groups with 6 replicates per group and 10 geese per replicate. Geese in the control group were fed a basal diet and the others in the experimental groups(groups 1,2, and 3) were fed experimental diets supplemented with 150, 300 and 450 mg/kg alfalfa flavonoids extraction(the concentration of it was 81%), respectively. The experiment had 7 days for pre-test and 42 days for formal test.The results showed that the final body weight and average daily intake of group 2 were significantly higher than those of other groups(P < 0.05). The average daily gain of group 2 was significantly higher than that in the control group and group 1(P < 0.05). There was no significant difference in feed-to-gain ratio between each group(P > 0.05). Pre-slaughter live weight, carcass weight, slaughter rate, semieviscerated weight, semi-eviscerated rate, eviscerated weight, eviscerated rate, leg muscle weight and leg muscle rate had no significant difference between each group(P > 0.05). The breast muscle weight and ratio of each test group were significantly higher than those in the control group(P < 0.05) and the group2 was the best. The abdominal fat weight and ratio in the group 1 were significantly higher than those in the control group and group 3(P < 0.05) and the tibia weight in the group 2 was significantly higher than that in the control group and group 1(P < 0.05); There were no significant differences in heart weight,liver weight and the gland stomach weight among all groups(P > 0.05). Spleen weight in test groups was significantly higher than that in the control group(P < 0.05). The bursa weight and muscular stomach weight in the group 2 were significantly higher than those in the control group and group 1(P < 0.05). In serum, total cholesterol, triglycerides, low-density lipoprotein and urea nitrogen in the group 2 were significantly lower comparing with those in the control group(P < 0.05). High-density lipoprotein in the group 2 was significantly higher than that in other groups(P < 0.05). There were no significant differences in total serum protein, albumin, globulin and albumin/globulin among all groups(P > 0.05). Alanine aminotransferase and aspartate transaminase(AST) in groups 2 and 3 were higher than those in the group1 and control group but not obvious(P > 0.05) and alkaline phosphatase(ALP) in groups 1 and 2 was higher than that in the control group and group 3(P > 0.05). It is concluded that alfalfa flavonoids extraction added in dietary feed improve the growth performance, organ development and blood biochemical indexes of Yangzhou geese. It is concluded that 300 mg/kg supplemental level of the dietary alfalfa flavonoids extraction is optimal in this experiment. | Yinyin Chen Xiaoxiao Gong Guodong Li Miao Lin Yongjiu Huo Shengli Li Guoqi Zhao | 2016 | Animal Nutrition2016，，4： | 14 |
| 3 | Cropland redistribution to marginal lands undermines environmental sustainability显示文摘Cropland redistribution to marginal land has been reported worldwide;however,the resulting impacts on environmental sustainability have not been investigated sufficiently.Here we investigated the environmental impacts of cropland redistribution in China.As a result of urbanization-induced loss of high-quality croplands in south China(~8.5 t ha^(-1)),croplands expanded to marginal lands in northeast(~4.5 t ha^(-1)) and northwest China(~2.9 t ha^(-1)) during 1990-2015 to pursue food security.However,the reclamation in these low-yield and ecologically vulnerable zones considerably undermined local environmental sustainability,for example increasing wind erosion(+3.47%),irrigation water consumption(+34.42%),fertilizer use(+20.02%) and decreasing natural habitats(-3.11%).Forecasts show that further reclamation in marginal lands per current policies would exacerbate environmental costs by 2050.The future cropland security risk will be remarkably intensified because of the conflict between food production and environmental sustainability.Our research suggests that globally emerging reclamation of marginal lands should be restricted and crop yield boost should be encouraged for both food security and environmental benefits. | Wenhui Kuang Jiyuan Liu Hanqin Tian Hao Shi Jinwei Dong Changqing Song Xiaoyong Li Guoming Du Yali Hou Dengsheng Lu Wenfeng Chi Tao Pan Shuwen Zhang Rafiq Hamdi Zherui Yin Huimin Yan Changzhen Yan Shixin Wu Rendong Li Jiuchun Yang Yinyin Dou Wenbin Wu Liqiao Liang Bao Xiang Shiqi Yang | 2022 | National Science Review2022，9，1： | 13 |
| 4 | NgAgo-based fabplla gene knockdown causes eye 3evelopmental defects in zebrafish显示文摘 | Yinyin Qin Yongming Wang Dong Liu | 2016 | Cell Research2016，26，12： | 13 |
| 5 | IL-17RD (Sef or IL-17RLM) interacts with IL-17 receptor and mediates IL-17 signaling显示文摘Interleukin-17 (IL-17 或 IL-17A ) 生产是 TH17 房间的一个特点,贡献多重自体免疫、煽动性的疾病的致病的 CD4+ T 淋巴细胞的一个新唯一的系。IL-17 受体(IL-17R 或 IL-17RA ) 为 IL-17 生物活动是必要的。新兴的数据建议 heteromeric 或 homomeric 受体建筑群的形成为 IL-17 发信号被要求。这里,我们证明孤儿受体 IL-17RD (Sef,类似的表示到 FGF 基因或 IL-17RLM ) 被联系并且有 IL-17R 的 colocalized。重要地, IL-17RD 调停 IL-17 发信号,用一个酶记者评估了由 24p3 的本国的倡导者开车, IL-17 目标基因。另外,主导否定地缺乏细胞内部的领域的 IL-17RD 异种压制 IL-17R-mediated IL-17 发信号。而且,象 IL-17R 一样的 IL-17RD 与 TRAF6 被联系,一个 IL-17R 下游的分子。这些结果显示 IL-17RD 是表明建筑群的 IL-17 受体的部分,因此为通过 heteromeric 或 homomeric 受体建筑群发信号的 IL-17 提供新奇证据。 | Zhili Rong Anan Wang Zhiyong Li Yongming Ren Long Cheng Yinghua Li Yinyin Wang Fangli Ren Xiaoning Zhang Jim Hu Zhijie Chang | 2009 | Cell Research2009，19，2： | 6 |
| 6 | Chemical compound cinobufotalin potently induces FOXO1-stimulated cisplatin sensitivity by antagonizing its binding partner MYH9显示文摘In this study,we present novel molecular mechanisms by which FOXO1 functions as a tumor suppressor to prevent the pathogenesis of nasopharyngeal carcinoma(NPC).First,we observed that FOXO1 not only controlled tumor stemness and metastasis,but also sensitized NPC cells to cisplatin(DDP)in vitro and in vivo.Mechanistic studies demonstrated that FOXO1-induced miR-200b expression through the GSK3β/β-catenin/TCF4 network-mediated stimulation of ZEB1,which reduced tumor stemness and the epithelial–mesenchymal transition(EMT)signal.Furthermore,we observed FOXO1 interaction with MYH9 and suppression of MYH9 expression by modulating the PI3K/AKT/c-Myc/P53/miR-133a-3p pathway.Decreased MYH9 expression not only reduced its interactions with GSK3β,but also attenuated TRAF6 expression,which then decreased the ubiquitin-mediated degradation of GSK3βprotein.Increased GSK3βexpression stimulated theβ-catenin/TCF4/ZEB1/miR-200b network,which increased the downstream tumor stemness and EMT signals.Subsequently,we observed that chemically synthesized cinobufotalin(CB)strongly increased FOXO1-induced DDP chemosensitivity by reducing MYH9 expression,and the reduction in MYH9 modulated GSK3β/β-catenin and its downstream tumor stemness and EMT signal in NPC.In clinical samples,the combination of low FOXO1 expression and high MYH9 expression indicated the worst overall survival rates.Our studies demonstrated that CB potently induced FOXO1-mediated DDP sensitivity by antagonizing its binding partner MYH9 to modulate tumor stemness in NPC. | YongHao Li Xiong Liu Xian Lin Menyang Zhao Yanyi Xiao Chen Liu Zixi Liang Zelong Lin Renhui Yi Zibo Tang Jiahao Liu Xin Li Qingping Jiang Libo Li Yinyin Xie Zhen Liu Weiyi Fang | 2019 | Signal Transduction and Targeted Therapy2019，4，1： | 6 |
| 7 | Nanosheet-structured K–Co–MoS_2 catalyst for the higher alcohol synthesis from syngas: Synthesis and activation显示文摘The nanosheets structured K–Co–MoS_2 catalyst was prepared through a one-step hydrothermal synthesis combined with the wetness impregnation. The fresh catalyst has a high dispersion of Co–Mo–S active phase and no Co_9S_8 is found. The pure H_2 activated catalyst shows a higher intrinsic activity, especially the C_(2+) OH selectivity for the higher alcohol synthesis compared to the one activated by 5% H_2/N_2 atmosphere. The reason is attributed to that the pure H_2 activation more effectively suppresses the formation of Co_9S_8 and stabilizes the Co–Mo–S active phase during the reaction due to the formation of SH species. | Huan Li Wei Zhang Yinyin Wang Meiling Shui Song Sun Jun Bao Chen Gao | 2019 | Journal of Energy Chemistry2019，28，3： | 5 |
| 8 | Distinct immune signatures discriminate between asymptomatic and presymptomatic SARS-CoV-2^(pos)subjects显示文摘Increasing numbers of SARS-CoV-2-positive(SARS-CoV-2^(pos))subjects are detected at silent SARS-CoV-2 infection stage(SSIS).Yet,SSIS represents a poorly examined time-window wherein unknown immunity patterns may contribute to the fate determination towards persistently asymptomatic or overt disease.Here,we retrieved blood samples from 19 asymptomatic and 12 presymptomatic SARS-COV-2^(pos)subjects,47 age/gender-matched patients with mild or moderate COVID-19 and 27 normal subjects,and interrogated them with combined assays of 44-plex CyTOF,RNA-seq and Olink.Notably,both asymptomatic and presymptomatic subjects exhibited numerous readily detectable immunological alterations,while certain parameters including more severely decreased frequencies of CD107a^(low)classical monocytes,intermediate monocytes,non-classical monocytes and CD62L^(hi)CD8^(+)Tnaive cells,reduced plasma STC1 level but an increased frequency of CD4^(+)NKT cells combined to distinguish the latter.Intercorrelation analyses revealed a particular presymptomatic immunotype mainly manifesting as monocytic overactivation and differentiation blockage,a likely lymphocyte exhaustion and immunosuppression,yielding mechanistic insights into SSIS fate determination,which could potentially improve 5ARS-CoV-2 management. | Shanhe Yu Caixia Di Shijun Chen Mingquan Guo Jiayang Yan Zhaoqin Zhu Li Liu Ruixue Feng Yinyin Xie Ruihong Zhang Juan Chen Mengxi Wang Dong Wei Hai Fang Tong Yin Jinyan Huang Saijuan Chen Hongzhou Lu Jiang Zhu Jieming Qu | 2021 | Cell Research2021，31，11： | 4 |
| 9 | Agricultural land loss in China's urbanization process显示文摘In China, urbanization of agricultural land around city agglomerations increases rapidly. Rapid urbaniza-tion of agricultural land affects food supply, land value and ecological balance in the society. In China, the urban built-up area had increased by 40% from 1996 to 2003. This increase came predominantly from farmland surrounding thecities. How the ongoing urbanization of China affects its agricultural land is the focus of this paper. In current studies, wehave found that population density; urbanization degree and personal income are key factors that influence the urbaniza-tion process. Based on this, relation model has been established and to predict the general trends of the urban areaexpansion in China in 2020. In 2020, the constructed urban area of China would be increased by 1.3 times compared with2003. In 2020, this study anticipates the conversion of about 32,562 sq. km. agricultural land of China for urban use. | Li Xiaoyun Cai Yinyin Zhu Daolin Zhang Anlu | 2006 | Ecological Economy2006，2，1： | 3 |
| 10 | Catalytic hydrogenation of aromatic nitro compounds by functionalized ionic liquids-stabilized nickel nanoparticles in aqueous phase:The influence of anions显示文摘Two kinds of nickel nanoparticles (NPs) well-dispersed in aqueous phase have been conveniently prepared by reducing nickel(II) salt with hydrazine in the presence of amino group (-NH2) functionalized ionic liquids:1-(3-aminopropyl)-2,3-dimethylimidazolium bromide ([AMMIM][Br]) and 1-(3-aminopropyl)-2,3-dimethylimidazolium acetate ([AMMIM][AcO]).The Ni(0) particles are composed of smaller ones which assemble in a blackberry-like shape.The Ni nanoparticles stabilized with [AMMIM][AcO] are much larger than those stabilized with [AMMIM][Br],and the former unexpectedly give much higher activity in the selective hydrogenation of citral and nitrobenzene (NB) in aqueous phase.The Ni(0) nanocatalysts dispersed in aqueous phase are stable enough to be reused at least five times without significant loss of catalytic activity and selectivity during the catalytic recycles. | HU Yu YU YinYin ZHAO XiuGe YANG HanMing FENG Bo LI Huan QIAO YunXiang HUA Li PAN ZhenYan HOU ZhenShan | 2010 | Science China Chemistry2010，53，7： | 3 |
| 11 | Rapid Urban Land Expansion in Earthquake-Prone Areas of China显示文摘A timely understanding of urban expansion in earthquake-prone areas is crucial for earthquake risk assessment and urban planning for earthquake mitigation.However, a comprehensive evaluation of urban expansion in earthquake-prone areas is lacking in China, especially in the context of rapid urbanization. Based on time series urban land data and seismic ground-motion parameter zonation maps, this study analyzed urban expansion in the most seismically hazardous areas(MSHAs) of China from1992 to 2015 on the national, regional, and city scales. The results show that urban land area in the MSHAs expanded by 6767 km^2 from 1992 to 2015, with a gain of 350%.Specifically, the increase in urban land area of small cities in the MSHAs of western China during this period was the fastest, 6.24 times greater than that at the national level. In terms of spatial patterns, the urban land patches in the MSHAs in 2015 were more fragmented than those in 1992 on all scales. The percentage of change in the number of patches and the landscape shape index of the urban land patches of small cities in the MSHAs of western China were the highest across all cities. Therefore, we believe that special attention should be paid to the cities in the MSHAs that exhibit the most rapid increases in both urban land area and fragmentation, especially the small cities in western China. It is imperative to integrate earthquake mitigation into the urban planning of these cities. | Qingxu Huang Shiting Meng Chunyang He Yinyin Dou Qiang Zhang | 2019 | International Journal of Disaster Risk Science2019，10，1： | 3 |
| 12 | The protective roles of tea tree oil extracts in bovine mammary epithelial cells and polymorphonuclear leukocytes显示文摘Background: Tea tree oil(TTO) plays an important role in antibacterial activity and alleviating the inflammatory responses. Bovine mammary epithelium and polymorphonuclear leukocytes(PMNL) can actively respond to bovine mastitis infection. However, regulatory effects of TTO extracts on the innate immune response of bovine mammary epithelial cells(BMECs) and PMNL remain not reported. Therefore, aim of the study was to evaluate the effects of TTO extracts on the m RNA levels of the genes involved in the innate immune response of BMECs and PMNL.Results: Our results demonstrated that addition of 0.025% and 0.05% TTO increased the proliferation of BMECs, and significantly enhanced(P < 0.05) the viability of BMECs exposed to Staphylococcus aureus(S. aureus). An inhibitory effect was observed against the growth of S. aureus by TTO incubation. The 0.05% TTO reduced S. aureus biofilm formation, association and invasion of S. aureus to BMECs, and changed the morphological and structural features of S. aureus. The proinflammatory cytokines IL-1β, IL-6, and TNF-α were decreased(P < 0.001) by the incubation of TTO. Interestingly, the expression of IL-8 known for PMNL chemotactic function was elevated(P < 0.05) by 0.05%TTO treatment. Consistently, 0.05% TTO increased the migration of PMNL in S. aureus-exposed BMECs when compared with S. aureus treatment alone(P < 0.05). In addition, PMNL incubated with 0.05% TTO decreased the levels of NFKB inhibitor alpha(NFKBIA) and TNF-α.Conclusions: Our results indicate that use of TTO can relieve the BMECs pro-inflammatory response caused by S.aureus and promote the migration of PMNL to mount the innate immune responses, and it may be novel strategy for the treatment of bovine mastitis caused by S. aureus. | Kang Zhan Tianyu Yang Baobao Feng Xinyu Zhu Yinyin Chen Yongjiu Huo Guoqi Zhao | 2020 | Journal of Animal Science and Biotechnology2020，11，4： | 3 |
| 13 | Polyamines mediate the effect of post-anthesis soil drying on starch granule size distribution in wheat kernels显示文摘Polyamines(PAs) are important endogenous plant growth regulators responding to environmental stress and mediating many physiological processes including grain filling in cereals.This study investigated whether PAs mediate the effect of post-anthesis soil drying on starch granule size distribution,starch content,and weight of superior and inferior kernels of wheat(Triticum aestivum L.).Two wheat cultivars were grown in pots.Three treatments,well-watered(WW),moderate soil drying(MD) and severe soil drying(SD),were imposed from 9 days post-anthesis until maturity.PA levels in kernels and small,medium and large granules were measured.The results showed that superior kernels had much higher free spermidine(Spd) and free spermine(Spm) concentrations,larger volumes of medium starch granules,and smaller-sized large granules than did inferior kernels under all the treatments.Compared to WW,MD significantly increased the concentrations of free Spd and free Spm,activities of soluble starch synthase and granule-bound starch synthase,volume of medium granules,and starch content and kernel weight of inferior kernels,and decreased the size of large granules.SD produced the opposite effect.Application of Spd or Spm to spikes produced effects similar to those of MD,and application of an inhibitor of Spd and Spm synthesis produced effects similar to those of SD.These results suggest that PAs mediate the effect of post-anthesis soil drying on starch biosynthesis in wheat kernels by regulating key enzymes in starch synthesis and that elevated PA levels under MD increase the volume of medium granules and kernel weight of inferior kernels. | Yunji Xu Mengting Qiu Yinyin Li Xiyang Qian Junfei Gu Jianchang Yang | 2016 | The Crop Journal2016，4，6： | 2 |
| 14 | Multifunctional electrospinning composite fibers for orthotopic cancer treatment in vivo显示文摘一个多功能的、双药的搬运人平台成功地被构造。核心壳组织了 NaGdF 4:Yb/Er@NaGdF4:Yb@mSiO2-polyethylene 乙二醇(作为 UCNPS 缩短了) 与 antitumor 药装载的 nanoparticles, doxorubicin (纪录影片) 被合并到 poly (-caprolactone)( 打印机控制语言) 和明胶与消炎的药装载了,消炎痛(MC ) 到形式 nanofibrous 织物(作为 MC/UCNPS/DOX 标记) 经由 electrospinning 过程。结果的多功能的旋转片能通过手术作为 orthotopic 化疗在老鼠的肿瘤地点直接被植入由从 mesoporous 硅二氧化物的控制版本纪录影片(通过 NaGdF 4:Yb/Er@NaGdF4:Yb 的双模型的成像在 vivo 在 MC/UCNPS/DOX 嵌入的 SiO 2) 和 upconversion fluorescence/magnetic 回声。 | Yinyin Chen Shi Liu Zhiyao Hou Pingan Ma Dongmei Yang Chunxia Li Jun Lin | 2015 | Nano Research2015，8，6： | 2 |
| 15 | The Impact of COVID-19 on Tuberculosis Patients’Behavior of Seeking Medical Care——China,2020显示文摘Summary What is already known on this topic?The coronavirus disease 2019(COVID-19)pandemic has disrupted the tuberculosis(TB)service system.However,the impact on TB patients in China remains unknown.What is added by this report?This report firstly addressed the impact of COVID-19 on TB patients in China.About half of TB patients did not revisit the hospital due to personal reasons.The reasons for irregular medication and postponing or cancelling examination after full treatment course were different. | Yinyin Xia Fei Huang Hui Chen Ni Wang Xin Du Wei Chen Tao Li Shitong Huan Miaomiao Sun Jianjun Liu Yanlin Zhao | 2021 | China CDC weekly2021，3，26： | 2 |
| 16 | Adversarial Attacks on Content-Based Filtering Journal Recommender Systems显示文摘Recommender systems are very useful for people to explore what they really need.Academic papers are important achievements for researchers and they often have a great deal of choice to submit their papers.In order to improve the efficiency of selecting the most suitable journals for publishing their works,journal recommender systems(JRS)can automatically provide a small number of candidate journals based on key information such as the title and the abstract.However,users or journal owners may attack the system for their own purposes.In this paper,we discuss about the adversarial attacks against content-based filtering JRS.We propose both targeted attack method that makes some target journals appear more often in the system and non-targeted attack method that makes the system provide incorrect recommendations.We also conduct extensive experiments to validate the proposed methods.We hope this paper could help improve JRS by realizing the existence of such adversarial attacks. | Zhaoquan Gu Yinyin Cai Sheng Wang Mohan Li Jing Qiu Shen Su Xiaojiang Du Zhihong Tian | 2020 | Computers, Materials & Continua2020，，9： | 2 |
| 17 | Validation of different personalized risk models of chemotherapy-induced nausea and vomiting:results of a randomized,double-blind,phase III trial of fosaprepitant for cancer patients treated with high-dose cisplatin显示文摘Background:Highly emetogenic chemotherapy induces emesis in cancer patients without prophylaxis.The purpose of this study was to evaluate the efficacy and safety of a fosaprepitant-based triple antiemetic regimen for the prevention of chemotherapy-induced nausea and vomiting(CINV)in patients with solid malignant tumors,determine risk factors and externally validate different personalized risk models for CINV.Methods:This phase III trial was designed to test the non-inferiority of fosaprepitant toward aprepitant in cancer patients who were to receive the first cycle of single-day cisplatin chemotherapy.The primary endpoint was complete response(CR)during the overall phase(OP)with a non-inferiority margin of 10.0%.Logistic regression modelswere used to assess the risk factors ofCRand no nausea.To validate the personalized risk models,the accuracy of the risk scoring systems was determined by measuring the specificity,sensitivity and area under the receiver operating characteristic(ROC)curve(AUC),while the predictive accuracy of the nomogram was measured using concordance index(C-index).Results:A total of 720 patients were randomly assigned.CR during the OP in the fosaprepitant group was not inferior to that in the aprepitant group(78.1%vs.77.7%,P=0.765)with a between-group difference of 0.4%(95%CI,-5.7%to 6.6%).Female sex,higher cisplatin dose(≥70 mg/m2),no history of drinking and larger body surface area(BSA)were significantly associated with nausea.The AUC for the acute and delayed CINV risk indexes was 0.68(95%CI:0.66-0.71)and 0.66(95%CI:0.61-0.70),respectively,and the C-index for nomogram CINV prediction was 0.59(95%CI,0.54-0.64).Using appropriate cutoff points,the three models could stratify patients with high-or low-risk CINV.No nausea and CR rate were significantly higher in the low-risk group than in the high-risk group(P<0.001).Conclusions:Fosaprepitant-based triple prophylaxis demonstrated non-inferior control for preventing CINV in patients treated with cisplatin-base chemotherapy.Female cancer patients without a history of alcohol consumption,with larger BSA and received high-dose cisplatin might be more vulnerable to CINV.Three personalized prediction models were well-validated and could be used to optimize antiemetic therapy for individual patients. | Yuanyuan Zhao Bing Zhao Gang Chen Yinlan Chen Zijun Liao Haiming Zhang Weineng Feng Yinyin Li Heng Weng Weidong Li Yuefen Zhou Biyong Ren Yanda Lu Jianhua Chen Zhenteng Liu Zhenzhong Su Wenliang Wang Li Zhang | 2023 | Cancer Communications2023，43，2： | 2 |
| 18 | Transverse Flow in Heavy-ion Reaction at Intermediate Energies显示文摘 | Liu Xingquan Yang Kun Huang Meirong Zhang Suyalatu Xi Yinyin Roy Wada Chen Zhiqiang | 2011 | IMP & HIRFL Annual Report2011，，1： | 2 |
| 19 | Internal Loads and Bioavailability of Phosphorus and Nitrogen in Dianchi Lake,China显示文摘Sediments have a significant influence on the cycling of nutrient elements in lake environments. In order to assess the distribution characteristics and estimate the bioavailability of phosphorus and nitrogen in Dianchi Lake, organic and inorganic phosphorus and nitrogen forms were analysed. The 210 Pb radiometric dating method was employed to study temporal changes in the phosphorus and nitrogen pools in Dianchi Lake. The result show that the total phosphorus(TP) and total nitrogen(TN) were both at high concentrations, ranging from 697.5–3210.0 mg/kg and 1263.7–7155.2 mg/kg, respectively. Inorganic phosphorus(IP) and total organic nitrogen(TON) were the main constituents, at percentages of 59%–78% and 74%–95%, respectively, in the sediments. Spatially, there was a decreasing trend in phosphorus and nitrogen contents from the south and north to the lake centre, which is related to the distribution pattern of local economic production. The burial rates of the various phosphorus and nitrogen forms increased in same spatially and over time. Particularly in the past two decades, the burial rates doubled, with that TN reached to 1.287 mg/(cm^2·yr) in 2014. As the most reactive forms, nitrate nitrogen(NO_3-N) and ammonia nitrogen(NH_4-N) were buried more rapidly in the south region, implying that the potential for releasing sedimentary nitrogen increased from north to south. Based on their concentrations and burial rates, the internal loads of phosphorus and nitrogen were analysed for the last century. A TP pool of 71597.6 t and a TN pool of 81191.7 t were estimated for Dianchi Lake. Bioavailable phosphorus and nitrogen pools were also estimated at 44468.0 t and 5429.7 t, respectively, for the last century. | WU Yalin HUANG Tao HUANG Changchun SHEN Yinyin LUO Yang YANG Hao YU Yanhong LI Ruixiao GAO Yan ZHANG Mingli | 2018 | Chinese Geographical Science2018，28，5： | 2 |
| 20 | Tuberculosis in Schools and Requirements for Prevention and Control in China显示文摘In recent years,although tuberculosis(TB)control in schools has achieved success to some extent,TB outbreaks still occur in schools from time to time.There are gaps in the response to TB outbreaks,which should be identified and addressed through a series of integrated measures that should be implemented and further strengthened.This article summarizes the circumstances of TB outbreaks in schools,their characteristics,and experiences and lessons that can be learned to improve TB prevention and control. | Hui Chen Yinyin Xia Canyou Zhang Hui Zhang Jun Cheng Yanlin Zhao | 2021 | China CDC weekly2021，3，3： | 2 |
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