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| 1 | 拉萨地体的起源和古生代构造演化显示文摘早期由于资料有限,对拉萨地体古生代时期的裂解、漂移、俯冲和碰撞历史的认知程度还很低。本文利用目前已有地质和地球化学资料,分析了拉萨地体的中生代岩石圈结构,探讨了拉萨地体的起源和古生代演化历史。大量长英质岩石的锆石Hf同位素和全岩Nd同位素表明,南部和北部拉萨地体以新生地壳为主,部分地区可能存在前寒武纪结晶基底,而中部拉萨地体是具有古元古代甚至太古代结晶基底的条带状微陆块。大量古生代沉积岩的碎屑锆石U-Pb年龄数据表明,拉萨地体约1170Ma的碎屑锆石年龄指标,明显不同于以约950Ma为碎屑锆石年龄指标的安多、羌塘和特提斯喜马拉雅。拉萨地体起源于澳大利亚大陆北缘是目前资料情况下的最合理解释。中部拉萨地体约492Ma的双峰式火山岩形成于活动大陆边缘背景,代表了古地理上位于澳大利亚大陆北缘的岩浆弧的一部分,可能与原特提斯洋岩石圈板片的断离有关。拉萨地体南缘和南羌塘的泥盆纪末期—石炭纪早期片麻状花岗岩类为存在明显幔源物质输入的S型花岗岩,可能形成于最终演化为松多特提斯洋的弧后盆地背景。中二叠世末期发生的拉萨地体与澳大利亚大陆北缘的碰撞造山事件可能触发了班公湖—怒江特提斯洋岩石圈的南向俯冲,并随后对拉萨地体的中生代构造岩浆演化发挥关键性作用。 | 朱弟成 赵志丹 牛耀龄 王青 Yildirim DILEK 董国臣 莫宣学 | 2012 | 高校地质学报2012，18，1： | 87 |
| 2 | Review of a challenging clinical issue:Intrahepatic cholestasis of pregnancy显示文摘Intrahepatic cholestasis of pregnancy(ICP) is a reversible pregnancy-specific cholestatic condition characterized by pruritus, elevated liver enzymes, and increased serum bile acids. It commences usually in the late second or third trimester, and quickly resolves after delivery. The incidence is higher in South American and Scandinavian countries(9.2%-15.6% and 1.5%, respectively) than in Europe(0.1%-0.2%). The etiology is multifactorial where genetic, endocrine, and environmental factors interact. Maternal outcome is usually benign, whereas fetal complications such as preterm labor, meconium staining, fetal distress, and sudden intrauterine fetal demise not infrequently lead to considerable perinatal morbidity and mortality. Ursodeoxycholic acid is shown to be the most efficient therapeutic agent with proven safety and efficacy. Management of ICP consists of careful monitoring of maternal hepatic function tests and serum bile acid levels in addition to the assessment of fetal well-being and timely delivery after completion of fetal pulmonary maturity. This review focuses on the current concepts about ICP based on recent literature data and presents an update regarding the diagnosis and management of this challenging issue. | Sebiha Ozkan Yasin Ceylan Orhan Veli Ozkan Sule Yildirim | 2015 | World Journal of Gastroenterology2015，21，23： | 53 |
| 3 | Endorectal ultrasonography versus phased-array magnetic resonance imaging for preoperative staging of rectal cancer显示文摘AIM: To compare the diagnostic accuracy of pelvic phased-array magnetic resonance imaging (MRI) and endorectal ultrasonography (ERUS) in the preoperative staging of rectal carcinoma. METHODS: Thirty-four patients (15 males, 19 females) with ages ranging between 29 and 75 who have biopsy proven rectal tumor underwent both MRI and ERUS examinations before surgery. All patients were evaluated to determine the diagnostic accuracy of depth of transmural tumor invasion and lymph node metastases. Imaging results were correlated with histopathological findings regarded as the gold standard and both modalities were compared in terms of predicting preoperative local staging of rectal carcinoma. RESULTS: The pathological T stage of the tumors was: pT1 in 1 patient, pT2 in 9 patients, pT3 in 21 patients and pT4 in 3 patients. The pathological N stage of the tumors was: pN0 in 19 patients, pN1 in 9 patients and pN2 in 6 patients. The accuracy of T staging for MRI was 89.70% (27 out of 34). The sensitivity was 79.41% and the specificity was 93.14%. The accuracy of T staging for ERUS was 85.29% (24 out of 34). The sensitivity was 70.59% and the specificity was 90.20%. Detection of lymph node metastases usingphased-array MRI gave an accuracy of 74.50% (21 out of 34). The sensitivity and specificity was found to be 61.76% and 80.88%, respectively. By using ERUS in the detection of lymph node metastases, an accuracy of 76.47% (18 out of 34) was obtained. The sensitivity and specificity were found to be 52.94% and 84.31%, respectively. CONCLUSION: ERUS and phased-array MRI are complementary methods in the accurate preoperative staging of rectal cancer. In conclusion, we can state that phased-array MRI was observed to be slightly superior in determining the depth of transmural invasion (T stage) and has same value in detecting lymph node metastases (N stage) as compared to ERUS. | Ahmet Mesrur Halefoglu Sadik Yildirim Omer Avlanmis Damlanur Sakiz Adil Baykan | 2008 | World Journal of Gastroenterology2008，14，22： | 35 |
| 4 | Efficacy and safety of tenofovir disoproxil fumarate in pregnancy for the prevention of vertical transmission of HBV infection显示文摘AIM:To evaluate the effects of tenofovir disoproxil fumarate(TDF)use during late pregnancy to reduce hepatitis B virus(HBV)transmission in highly viremic mothers.METHODS:This retrospective study included 45 pregnant patients with hepatitis B e antigen(+)chronic hepatitis B and HBV DNA levels>107copies/mL who received TDF 300 mg/d from week 18 to 27 of gestation(n=21).Untreated pregnant patients served as controls(n =24).All infants received 200 IU of hepatitis B immune globulin(HBIG)within 24 h postpartum and 20μg of recombinant HBV vaccine at 4,8,and 24 wk.Perinatal transmission rate was determined by hepatitis B surface antigen and HBV DNA results in infants at week 28.RESULTS:At week 28,none of the infants of TDFtreated mothers had immunoprophylaxis failure,whereas2(8.3%)of the infants of control mothers had immunoprophylaxis failure(P=0.022).There were no differences between the groups in terms of adverse events in mothers or congenital deformities,gestational age,height,or weight in infants.At postpartum week 28,significantly more TDF-treated mothers had levels of HBV DNA<250 copies/mL and normalized alanine aminotransferase compared with controls(62%vs none,P<0.001;82%vs 61%,P=0.012,respectively).CONCLUSION:TDF therapy during the second or third trimester reduced perinatal transmission rates of HBV and no adverse events were observed in mothers or infants. | Mustafa Kemal Celen Duygu Mert Müzeyyen Ay Tuba Dal Safak Kaya Necmettin Yildirim Serda Gulsun Tunga Barcin Sevgi Kalkanli Mehmet Sinan Dal Celal Ayaz | 2013 | World Journal of Gastroenterology2013，19，48： | 26 |
| 5 | 西藏雅鲁藏布蛇绿岩形成构造环境的地球化学鉴别显示文摘本文对西藏雅鲁藏布蛇绿岩带中部日喀则地区夏鲁蛇绿岩中的基性岩石进行了元素地球化学研究。岩石为低钾亚碱性玄武质岩石,具有低TiO2(0.64%~1.5%)、低K2O(<0.69%)、富Na2O(2.5%~6.0%)、烧失量普遍较高(2.0%~7.5%)的特征,表明样品普遍遭受蚀变。岩石具有与N-MORB类似的稀土元素和总体一致的微量元素特征,但是岩石明显富集大离子亲石元素和亏损高场强元素,显示了洋脊玄武岩向着岛弧岩浆作用的过渡趋势。日喀则蛇绿岩不是典型的洋中脊成因,应为SSZ型蛇绿岩,可能形成于与洋内俯冲有关的SSZ型的弧后或者弧前盆地中。对东西延伸超过1500km的雅鲁藏布蛇绿岩246套基性岩石形成的构造环境进行的地球化学判别,表明至少存在大陆岛弧型、地幔柱-洋内热点型、洋中脊-大洋岛弧型和典型大洋岛弧型等四种类型洋壳,揭示了特提斯洋存在多种构造环境的特征,有利于恢复和还原一个长期演化的、丰富的特提斯洋。 | 李文霞 赵志丹 朱弟成 董国臣 周肃 莫宣学 Don DePAOLO Yildirim DILEK | 2012 | 岩石学报2012，28，5： | 23 |
| 6 | Tooth regeneration: a revolution in stomatology and evolution in regenerative medicine显示文摘A tooth is a complex biological organ and consists of multiple tissues including the enamel, dentin, cementum and pulp. Tooth loss is the most common organ failure. Can a tooth be regenerated? Can adult stem cells be orchestrated to regenerate tooth structures such as the enamel, dentin, cementum and dental pulp, or even an entire tooth? If not, what are the therapeutically viable sources of stem cells for tooth regeneration? Do stem cells necessarily need to be taken out of the body, and manipulated ex vivo before they are transplanted for tooth regeneration? How can regenerated teeth be economically competitive with dental implants? Would it be possible to make regenerated teeth affordable by a large segment of the population worldwide? This review article explores existing and visionary approaches that address some of the above-mentioned questions. Tooth regeneration represents a revolution in stomatology as a shift in the paradigm from repair to regeneration: repair is by metal or artificial materials whereas regeneration is by biological restoration. Tooth regeneration is an extension of the concepts in the broad field of regenerative medicine to restore a tissue defect to its original form and function by biological substitutes. | Sibel Yildirim Susan Y. Fu Keith Kim Hong Zhou Chang Hun Lee Ang Li Sahng Gyoon Kim Shuang Wang Jeremy J. Mao | 2011 | International Journal of Oral Science2011，3，3： | 16 |
| 7 | Four billion years of ophiolites reveal secular trends in oceanic crust formation显示文摘We combine a geological,geochemical and tectonic dataset from 118 ophioiite complexes of the major global Phanerozoic orogenic belts with similar datasets of ophiolites from 111 Precambrian greenstone belts to construct an overview of oceanic crust generation over 4 billion years.Geochemical discrimination systematics built on immobile trace elements reveal that the basaltic units of the Phanerozoic ophiolites are dominantly subduction-related(75%),linked to backarc processes and characterized by a strong MORB component,similar to ophiolites in Precambrian greenstone sequences(85%).The remaining 25%Phanerozoic subduction-unrelated ophiolites are mainly(74%) of Mid-Ocean-Ridge type(MORB type),in contrast to the equal proportion of Rift/Continental Margin,Plume,and MORB type ophiolites in the Precambrian greenstone belts.Throughout the Phanerozoic there are large geochemical variations in major and trace elements,but for average element values calculated in 5 bins of 100 million year intervals there are no obvious secular trends.By contrast,basaltic units in the ophiolites of the Precambrian greenstones(calculated in 12 bins of 250 million years intervals),starting in late Paleo- to early Mesoproterozoic(ca.2.0-1.8 Ga),exhibit an apparent decrease in the average values of incompatible elements such as Ti,P,Zr,Y and Nb,and an increase in the compatible elements Ni and Cr with deeper time to the end of the Archean and into the Hadean.These changes can be attributed to decreasing degrees of partial melting of the upper mantle from Hadean/Archean to Present.The onset of geochemical changes coincide with the timing of detectible changes in the structural architecture of the ophiolites such as greater volumes of gabbro and more common sheeted dyke complexes,and lesser occurrences of ocelli(varioles) in the pillow lavas in ophiolites younger than 2 Ga.The global data from the Precambrian ophiolites,representative of nearly 50%of all known worldwide greenstone belts provide significant clues for the operation of plate tectonic processes in the Archean. | Harald Furnes Maarten de Wit Yildirim Dilek | 2014 | Geoscience Frontiers2014，5，4： | 13 |
| 8 | 西藏拉萨地块过铝质花岗岩中继承锆石的物源区示踪及其古地理意义显示文摘富含继承锆石的过铝质花岗岩一般来源于富铝质岩石(如变泥质岩)的部分熔融,因而分析这些继承锆石的U-Pb年龄可以像分析沉积岩碎屑锆石的U-Pb年龄一样,提供过铝质花岗岩源区物质中碎屑沉积物物源区的丰富信息。本文报道了中部拉萨地块早侏罗世过铝质花岗岩的全岩地球化学和锆石U-Pb年代学数据,结合拉萨地块已有二叠纪和晚三叠世过铝质花岗岩的继承锆石年代学数据,总结了目前已有的拉萨地块过铝质花岗岩的继承锆石U-Pb年龄特征(共199个谐和测点)。这些过铝质花岗岩属强过铝质S型花岗岩,其中的继承锆石定义了1250~1100Ma(峰值1181±14Ma)和550~450Ma(峰值494±7Ma)2个最突出的年龄群,分别可比于拉萨地块古生代沉积岩的碎屑锆石年龄峰值(约1170Ma)和寒武纪火山岩的侵位时代,明显不同于西羌塘、安多和特提斯喜马拉雅新元古代-古生代沉积岩中的碎屑锆石年龄频谱。拉萨地块过铝质花岗岩中约1181Ma的继承锆石,可能与拉萨地块古生代沉积岩中的同期碎屑锆石一样,都来自澳大利亚南西部Albany-Fraser造山带和东南极Wilkes等地,而约494的继承锆石,既可能来自澳大利亚西部,也可能来自拉萨地块本地。本文提供了拉萨地块与澳大利亚大陆北缘具有古地理联系的过铝质花岗岩继承锆石U-Pb年龄证据。拉萨地块的研究实践表明,采用过铝质花岗岩继承锆石和古生代沉积岩碎屑锆石相结合的锆石U-Pb年代学方法,可为重建冈瓦纳大陆北缘其它微陆块的古地理和构造岩浆演化提供重要约束。 | 朱弟成 赵志丹 牛耀龄 王青 DILEK Yildirim 管琪 刘勇胜 莫宣学 | 2011 | 岩石学报2011，27，7： | 12 |
| 9 | Association of ezrin expression in intestinal and diffuse gastric carcinoma with clinicopathological parameters and tumor type显示文摘AIM: To investigate the correlation between ezrin expression and types of gastric carcinoma and clinicopathological variables. METHODS: We examined ezrin protein expression in 75 gastric carcinoma (53 intestinal types of adenocarcinoma, 22 diffuse types of carcinoma) tissues by immunohistochemistry. The results were compared with clinicopathological parameters such as tumor type, grade of tumor, clinical stage, presence of metastatic lymph node, and depth of invasion. RESULTS: Ezrin immunostaining was positive in 43 cases (81.1%) of intestinal type and in 9 (40.9%) cases of diffuse type adenocarcinomas (P < 0.001). In gastric carcinomas, the expression of ezrin protein correlated with the status of H pylori and survival. There was no correlation between expression of ezrin with TNM stage and histological grade of gastric carcinomas (P > 0.05). CONCLUSION: The low expression of ezrin implicates the loss of adhesion in diffuse carcinomas. Furthermore, overexpression of ezrin in carcinomas with H pylori infection may be a genuine specific pathway in which H pylori may cause/initiate gastric carcinoma. | Nebil Bal Sedat Yildirim Tarik Z Nursal Filiz Bolat Fazilet Kayaseluk | 2007 | World Journal of Gastroenterology2007，13，27： | 9 |
| 10 | Diamonds Discovered from High–Cr Podiform Chromitites of Bulqiza,Eastern Mirdita Ophiolite,Albania显示文摘Various combinations of diamond, moissanite, zircon, corundum, rutile and titanitehave been recovered from the Bulqiza chromitites. More than 10 grains of diamond have been recovered, most of which are pale yellow to reddish–orange to colorless. The grains are all 100–300 μm in size and mostly anhedral, but with a range of morphologies including elongated, octahedral and subhedral varieties. Their identification was confirmed by a characteristic shift in the Raman spectra between 1325 cm^(-1) and 1333 cm^(-1), mostly at 1331.51 cm^(-1) or 1326.96 cm^(-1). This investigation extends the occurrence of diamond and moissanite to the Bulqiza chromitites in the Eastern Mirdita Ophiolite. Integration of the mineralogical, petrological and geochemical data of the Bulqiza chromitites suggests their multi–stage formation. Magnesiochromite grains and perhaps small bodies of chromitite formed at various depths in the upper mantle, and encapsulated the ultra–high pressure, highly reduced and crustal minerals. Some oceanic crustal slabs containing the magnesiochromite and their inclusion were later trapped in suprasubduction zones, where they were modified by tholeiitic and boninitic arc magmas, thus changing the magnesiochromite compositions and depositing chromitite ores in melt channels. | XIONG Fahui YANG Jingsui ROBINSON Paul T. DILEK Yildirim MILUSHI Ibrahim XU Xiangzhen ZHOU Wenda ZHANG Zhongming RONG He | 2017 | Acta Geologica Sinica(English Edition)2017，91，2： | 9 |
| 11 | A microporous aluminum-based metal-organic framework for high methane,hydrogen,and carbon dioxide storage显示文摘We report a microporous aluminum-based metal-organic framework(MOF),BUT-22 for high methane(CH_(4)),hydrogen(H_(2)),and carbon dioxide(CO2)storage.At 296 K and 80 bar,BUT-22 exhibits a high gravimetric CH4 storage capacity of 530 cm^(3)(STP)/g(0.379 g/g).BUT-22 also has a high gravimetric H_(2)storage capacity of 12 wt.%at 100 bar and 77 K.In addition,the CO_(2)adsorption studies revealed that BUT-22 exhibits a high absolute gravimetric CO2 uptake of 1.7 g/g at 296 K and 40 bar. | Bin Wang Xin Zhang Hongliang Huang Zhangjing Zhang Taner Yildirim Wei Zhou Shengchang Xiang Banglin Chen | 2021 | Nano Research2021，14，2： | 8 |
| 12 | Association of CagA and VacA presence with ulcer and non-ulcer dyspepsia in a Turkish population显示文摘AIM: The mostly known genotypic virulence features, of H. pyloriare cytotoxin associated gene A (ragA) and Vacuolating cytotoxin gene A (VacA). We investigated the association of these major virulence factors with ulcer and non-ulcer dyspepsia in our region.METHODS: One hundred and forty two dyspeptic patients were studied (average age 44.8±15.9 years, range 15-87years, 64 males and 78 females). Antral and corpus biopsies were taken for detecting and genotyping of H. pylori. 107patients who were H. pylori positive by histological assessment were divided into three groups according to endoscopic findings: Duodenal ulcer (DU), gastric ulcer (GU)and non-ulcer dyspepsia (NUD). The polymerase chain reaction (PCR) was used to detect CagA and VacA genes of H.pylori using specific primers.RESULTS: H.pyloriwas isolated from 75.4 % (107/142) of the patients. Of the 107 patients, 66 (61.7 %) were cagApositive and 82 (76.6 %) were Vacl-positive. CagA gene was positively associated with DU and GU (P<0.01, P<0.02),but not with NUD (P>0.05). Although VacA positivity in ulcer patients was higher than that in NUD group, the difference was not statistically significant (P>0.05).CONCLUSION: There is a significantly positive association between CagA genes and DU and GU. The presence of VacA is not a predictive marker for DU, GU, and NUD in our patients. | Kantarceken Bulent Aladag Murat Atik Esin Koksal Fatih Harputluoglu MMMurat Harputluoglu Hakan Karincaoglu Melih Ares Mehmet Yildirim Bulent Hilmioglu Fatih | 2003 | World Journal of Gastroenterology2003，9，7： | 8 |
| 13 | Mechanical and Antibacterial Properties of Injection Molded Polypropylene/TiO_2 Nano-Composites:Effects of Surface Modification显示文摘Polypropylene (PP)/titanium dioxide (TiO2) nano-composites were prepared by melt compounding with a twin screw extruder. Nanoparticles were modified prior to melt mixing with maleic anhydride grafted styrene-ethylene-butylene-styrene (SEBS-g-MA) and silane. The composites were injection molded and mechanical tests were applied to obtain tensile strength, elastic modulus and impact strength. Antibacterial efficiency test was applied on the injection molded composite plaques by viable cell counting technique. The results showed that the composites including SEBS-g-MA and silane coated TiO2 gave better mechanical properties than the composites without SEBS-g-MA. Antibacterial efficiency of the composites varied according to the dispersion and the concentration of the particles and it was observed that composites at low content of TiO2 showed higher antibacterial property due to the better photocatalytic activity of the particles during UV exposure. | Mirigul Altan Huseyin Yildirim | 2012 | Journal of Materials Science & Technology2012，28，8： | 7 |
| 14 | In vitro antibacterial and antitumor activities of some medicinal plant extracts, growing in Turkey显示文摘Objective: To investigate antibacterial and antitumor activities of 51 different extracts prepared with 3 types of solvents (water, ethanol and methanol) of 16 different plant species (Ajuga reptans (A. reptans) L., Phlomis pungens (P. pungens) Willd., Marrubium astracanicum (M. astracanicum) Jacq., Nepeta nuda (N. nuda) L., Stachys annua (S. annua) L., Genista lydia (G. lydia) Boiss., Nuphar lutea (N. lutea) L., Nymphaea alba (N. alba) L., Vinca minor (V. minor) L., Stellaria media (S. media) L., Capsella bursa-pastoris (C. bursa-pastoris) L., Galium spurium (G. spurium) L., Onosma heterophyllum (O. heterophyllum) Griseb., Reseda luteola (R. luteola) L., Viburnum lantana (V. lantana) L. and Mercurialis annua (M. annua) L.) grown in Turkey was conducted. Methods: Antibacterial activity was evaluated with 10 bacteria including Streptococcus pyogenes (S. pyogenes), Staphylococcus aureus (S. aureus), Staphylococcus epidermidis (S. epidermidis), Escheria coli (E. coli), Pseudomonas aeruginosa (P. aeruginosa), Salmonella typhimurium (S. typhimurium), Serratia marcescens (S. marcescens), Proteus vulgaris (P. vulgaris), Enterobacter cloacae (E. cloacea), and Klebsiella pneumoniae (K. pneumoniae) by using disc diffusion method. Antitumor activity was evaluated with Agrobacterium tumefaciens (A. tumefaciens)-induced potato disc tumor assay. Results: Best antibacterial activity was obtained with ethanolic extract of P. pungens against S. pyogenes . Ethanolic and methanolic extract of N. alba and ethanolic extract of G. lydia also showed strong antibacterial activities. Results indicated that alcoholic extracts especially ethanolic extracts exhibited strong antibacterial activity against both gram-positive and gram-negative bacteria. Best antitumor activity was obtained with methanolic extracts of N. alba and V. lantana (100% tumor inhibition). Ethanolic extract of N. alba , alcoholic extracts of N. lutea , A. reptans and V. minor flowers, methanolic extracts of G. lydia and O. heterophyllum and ethanolic extract of V. lantana and aqueous extract of V. minor leaves exhibited strong tumor inhibitions. Conclusions: In near future works, identification of active components can be studied for plant extracts having strong bioactivity. | Arzu Birinci Yildirim Fatma Pehlivan Karakas Arzu Ucar Turker | 2013 | Asian Pacific Journal of Tropical Medicine2013，6，8： | 6 |
| 15 | Driver sleepiness,fatigue,careless behavior and risk of motor vehicle crash and injury:Population based case and control study显示文摘Background: A few studies have been conducted to determine the relationship between road motor vehicle crashes(MVC) and serious injuries related to tiredness, fatigues and sleeping.Aim: To determine the effects of aggressive behaviour, driver sleepiness and fatigue on MVC and related injuries among Turkish population.Design and setting: Population-based case and control study conducted at the accident emergency departments of hospitals and roads.Subjects: 515 car drivers involved in crashes with injury were admitted to hospital and 1030 car drivers involved while driving on public roads as control group during the study period.Methods: The Manchester driver behaviour questionnaire(DBQ) measured the aberrant driving behaviours leading to accidents. Participants completed a fatigue severity scale(FSS) and Stanford Sleeping questionnaire an epworth scale with items related to sociodemographic information, driving experiences, adherence to traffic laws(such as speed limits and seat belt), and drivers' driving records.Results: In a representative sampling, participant's age ranged from 25 to 65 and the mean and standard deviation were 36.5 ± 7.8 for cases and 37.0 ± 8.0 for controls. There was a significant difference in both group of drivers regarding BMI, level of education, marital status, driving experience, seat belt use, excessive speed limits, physical activity number of sleeping hours, mobile phone use, and cigarette smoking habit(p = 0.017). Also, there was a significant higher mean score on all the DBQ violation questions among case group in comparison with the control group(p < 0.001). Further, cases had higher prevalence of Epworth sleeping disorders(p < 0.001) and fatigue severity(p = 0.003) compared to control drivers. Multivariate logistic regression revealed that excessive speed, fatigue, lapses, errors, Stanford sleepiness score, violations, mobile phone use and Epworth sleepiness scale were significantly associated with injury involvement in vehicle crash, after adjusting for driving experience and annual mileage.Conclusion: The current study confirmed that drivers with chronic fatigue, acute sleepiness,and careless driver behavior may significantly increases the risk of road crash which can be lead to serious injury. | Abdulbari Bener Erol Yildirim Turker Ozkan Timo Lajunen | 2017 | Journal of Traffic and Transportation Engineering(English Edition)2017，4，5： | 5 |
| 16 | Probing the Troodos Ophiolite:IGCP-649 Workshop and Field Excursion Held in Agros-Cyprus显示文摘The second IGCP-649 Workshop,held in Agros-Cyprus during 14-20 May 2016,brought together nearly fifty international scientists from around the world,and included a 5-day field excursion on the classic Troodos ophiolite.Organized by the IGCP-649 Project Leadership and the Geological Survey Department of Cyprus。 | YANG Jingsui Julian PEARCE Yildirim DILEK | 2016 | Acta Geologica Sinica(English Edition)2016，90，3： | 4 |
| 17 | Application of the modern ophiolite concept with special reference to Precambrian ophiolites显示文摘Much has been learned in the past 40 years about the great diversity of the internal structure and geochemical compositions of Phanerozoic ophiolites, indicating that these on-land fragments of ancient oceanic lithosphere formed in distinctly different tectonic settings during their igneous evolution. Recent studies in Archean and Proterozoic greenstone belts have shown that the Precambrian rock record may also include exposures of a diverse suite of ophiolite complexes as part of craton development in the early history of the Earth. We review the salient features of the Precambrian ophiolite record to highlight what has been learned about Precambrian oceanic spreading systems since the original Penrose definition of ophiolites in 1972. Some of the diagnostic, characteristic, typical, and rare aspects of ophiolites of all ages are presented in a table in order to help determine if tectonically deformed and metamophosed sequences in Precambrian shield areas may be considered as ophiolites. The results of this comparative study are important in that they enable researchers to more realistically characterize allochthonous mafic/ultramafic rock sequences as ophiolitic or non-ophiolitic. This approach is more deterministic in contrast to some other arbitrary classification schemes requiring three or four of the Penrose-style ophiolitic units to be present in the Precambrian record for a specific rock sequence to be considered ophiolitic. Once these tectonic fragments are recognized as remnants of ancient oceanic lithosphere, great progress shall be made in understanding early Earth history. We discuss the significance and implications of the Precambrian ophiolite record to constrain the mode and nature of the plate tectonics that operated in deep time. | Timothy M. KUSKY WANG Lu Yildirim DILEK Paul ROBINSON PENG SongBai HUANG XuYa | 2011 | Science China Earth Sciences2011，54，3： | 4 |
| 18 | Effect of Boron and Heat Treatment on Mechanical Properties of White Cast Iron for Mining Application显示文摘Heat treatment methods were applied to white cast iron for improving the impact and wear resistance. Additionally, chemical composition optimization was made. Furthermore, the effect of boron addition on such applications was investigated. Samples were investigated by using optical and electron microscope methods. Hardness, wear and impact tests were conducted. The results showed that the secondary carbides in the standard alloy were iron-enriched, needle-like carbides M3C when the boron-added alloy contained Fe23(C,B)6 type, globular secondary carbides. It was concluded that heat treatment B provided higher wear and hardness properties, compared to the standard heat treatment. Optimum mechanical properties were obtained by lower destabilisation temperatures and increasing temperature reduced the wear resistance and hardness. | Havva Kazdal Zeytin Hakan Yildirim Banu Berme Selim Duduoglu Gürkan Kazdal Adem Deniz | 2011 | Journal of Iron and Steel Research(International)2011，18，11： | 4 |
| 19 | Clustering Seismic Activities Using Linear and Nonlinear Discriminant Analysis显示文摘Identification and classification of different seismo-tectonic events with similar characteristics in a region of interest is one of the most important subjects in seismic hazard studies.In this study,linear and nonlinear discriminant analyses have been applied to classify seismic events in the vicinity of Istanbul.The vertical components of the digital velocity seismograms are used for seismic events with magnitude(Md)between 1.8 and 3.0 that occurred between 2001 and 2004.Two,time dependent parameters,complexity and S/P peak amplitude ratio are selected as predictands.Linear,quadratic,diaglinear and diagquadratic discriminant functions are investigated.Accuracy of methods with an additional adjusted quadratic models are 96.6%,96.6%,95.5%,96.6%,and 97.6%,respectively with a various misclassified rate for each class.The performances of models are justified with cross validation and resubstitution error.Although all models remarkably well performed,adjusted quadratic function achieved the best success rate with just 4 misclassified events out of 179,even better compared to complex methods such as,self organizing method,k-means,Gaussion mixture models that applied to same dataset in literature. | H Serdar Kuyuk Eray Yildirim Emrah Dogan Gunduz Horasan | 2014 | Journal of Earth Science2014，25，1： | 4 |
| 20 | Different accelerated corneal collagen cross-linking treatment modalities in progressive keratoconus显示文摘Background:To compare the outcomes of two different protocols of accelerated corneal crosslinking(CXL)on visual,corneal high order aberrations(HOA)and topographic parameters in patients with progressive keratoconus.Methods:In this prospective comparative study,sixty-six eyes of 66 patients with progressive keratoconus were divided into two groups;37 eyes in Group 1 received 18 mW/cm^(2) for five minutes,and 29 eyes in Group 2 were treated with 9 mW/cm^(2) for 10 min.The uncorrected distant visual acuity(UCVA),best-corrected distant visual acuity(BCVA),corneal HOAs and topography parameters were measured preoperatively and postoperatively at the end of 12 months.The data for the two groups were compared statistically.Results:The mean UCVA and BCVA were significantly improved at the postoperative 12 months compared with the preoperative values in both groups(P<0.05 for all).A significant improvement in corneal HOAs was observed in both groups(P<0.05 for all).The change in corneal coma value was significantly higher in Group 2(P<0.05).The change in keratometric values K1,K2,AvgK and maximum keratometry(AKf)were significantly higher in Group 2(P<0.05 for all).The regression model showed that the most important factor predicting the change in AKf was the type of CXL(β=−0.482,P=0.005).Conclusions:Accelerated CXL using 10 min of UVA irradiance at 9 mW/cm^(2) showed better topographic improvements and coma values than five minutes of UVA irradiance at 18 mW/cm^(2) independent of keratoconus severity. | Ahmet Kirgiz Mustafa Eliacik Yusuf Yildirim | 2019 | Eye and Vision2019，6，1： | 4 |
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