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| 1 | In-line X-ray phase-contrast imaging of murine liver microvasculature ex vivo显示文摘Imaging blood vessels is of importance for determining the vascular distribution of organs and tumors.Phase-contrast X-ray imaging can reveal the vessels in much more detail than conventional X-ray absorption method.Visualizing murine liver microvasculature ex vivo with phase-contrast X-ray imaging was performed at Shanghai Synchrotron Radiation Facility.Barium sulfate and physiological saline were used as contrast agents for the blood vessels.Blood vessels of <Φ20μm could be detected by replacing resident blood with physiological saline or barium sulfate.An entire branch of the portal vein (from the main axial portal vein to the ninth generation of branching) could be captured in a single phase-contrast image.It is demonstrated that selective angiography based on phase contrast X-ray imaging,with a physiological material of low Z elements (such as saline) being the contrast agent,is a viable imaging strategy.Further efforts will be focused on using the technique to image tumor angiogenesis. | LI Beilei XU Min WU Weizhong PENG Guanyun ZHANG Xi PENG Yifeng SHI Hongcheng CHEN Shaoliang | 2012 | Nuclear Science and Techniques2012，23，1： | 5 |
| 2 | Flexible rechargeable Ni//Zn battery based on self-supported NiCo_2O_4 nanosheets with high power density and good cycling stability显示文摘The overall electrochemical performances of Ni-Zn batteries are still far from satisfactory, specifically for rate performance and cycling stability Herein, we demonstrated a high-performance flexible Ni//Zn battery with outstanding durability and high power density based on selfsupported NiCo_2 O_4 nanosheets as cathode and Zn nanosheets as anode. This Ni//Zn battery is able to deliver a remarkable capacity of183.1 mAh g^(-1) and a good cycling performance(82.7% capacity retention after 3500 cycles). More importantly, this battery achieves an admirable power density of 49.0 kW kg^(-1) and energy density of 303.8 Wh kg^(-1), substantially higher than most recently reported batteries. With such excellent electrochemical performance, this battery will have great potential as an ultrafast power source in practical application. | Haozhe Zhang Xinyue Zhang Haodong Li Yifeng Zhang Yinxiang Zeng Yexiang Tong Peng Zhang Xihong Lu | 2018 | Green Energy & Environment2018，3，1： | 5 |
| 3 | Dysfunction of cognition patterns measured by MATRICS Consensus Cognitive Battery (MCCB) among first episode schizophrenia patients and their biological parents显示文摘背景:精神分裂症的临床表现为特征性的知觉、思维、情感和行为等障碍。认知障碍也是精神分裂症核心症状之一。20世纪70年代早期Gallhofer曾提出过,精神分裂症除有阳性或阴性症状,也存在认知障碍。许多研究表明,精神分裂症的一级亲属中存在遗传易感性。认知障碍不仅急性期存在,维持巩固期也会有。有研究还显示,精神分裂症健康的一级亲属亦存在认知缺陷。但对精神分裂症及其生物学父母的认知特征研究仍缺乏。本研究,我们假设精神分裂症及其生物学父母存在特定的认知功能障碍,拟采用认知功能成套测验共识版(MATRICS Consensus Cognitive Battery,MCCB)中文版,以探讨精神分裂症患者及其生物学父母的认知模式。目的:精神分裂症的认知特征可能受到其生物学父母认知模式的影响。研究旨在描绘精神分裂症患者与其父母之间的功能失调的认知模式。方法:采用认知功能成套测验共识版(MCCB,一种新的测量工具)评估29例首发精神分裂症(符合ICD-10精神分裂症诊断标准,年龄17-45岁),58例精神分裂症患者的生物学父母(年龄40-70岁)和46例健康对照(年龄40-70岁)的认知功能,以探讨精神分裂症患者及其生物学父母之间的认知功能障碍之间的关系。所有数据使用SPSS18.0统计软件进行分析。结果:1)男性精神分裂症患者与其父亲相比在MCCB认知功能测定的6个维度有明显认知缺陷(除社会认知功能外)。女性患者的工作记忆和问题推理能力都低于其母亲。2)患者父亲和健康对照组之间的工作记忆和推理问题也存在显著差异。3)与健康对照组相比,患者母亲在问题推理方面没有明显的差异,但视觉记忆有异常。结论:首发精神分裂症患者及其生物学父母在6个维度存在认知功能障碍。患者父母在工作记忆、问题推理和视觉记忆等方面也存在明显功能障碍。仍需深入研究以揭示首发精神分裂症及其生物学父母存在认知功能障碍的潜在机制。 | Aiai CAO Ting SHEN Haibin LI Chuangxin WU Marita MCCABE David MELLOR Linda BYRNE Jie ZHANG Jia HUANG Daihui PENG Yifeng XU | 2017 | 上海精神医学2017，29，3： | 5 |
| 4 | Interface-induced formation of onion-like alloy nanocrystals by defects engineering显示文摘缺点的控制介绍的能力,在基于磅的 nanocrystals (NC ) 的特别地成双的缺点提供可能性调整基于磅的 nanocatalyst 的表演。然而,因为高内部的紧张,精力在孪生的结构存在,在基于磅的 NC 的缺点的制造是足够地挑战性的。这里,我们证明在 PtCu nanoparticles 上提供精确控制的一条低温度的导致接口的汇编途径集合在 hexadecylamine/water 接口,产出暴露的像洋葱的 PtCu NC 成双的缺点的高密度。而且,弯曲机制被建议阐明膨胀的成双的缺点和格子(收缩) 的外观基于错误改正了扫描传播电子显微镜学分析。这个工作打开新线路在 metalbased 合金 NC 设计缺点,启用在催化作用的更多的机会。 | Wei Jia Yuen Wu Yifeng Chen Dongsheng He Jinpeng Li Yu Wang Zhuo Wang Wei Zhu Chen Chen Qing Peng Dingsheng Wang Yadong Li | 2016 | Nano Research2016，9，2： | 5 |
| 5 | Effects of L-3-n-butylphthalide on caspase-3 and nuclear factor kappa-B expression in primary basal forebrain and hippocampal cultures after beta-amyloid peptide 1-42 treatment显示文摘BACKGROUND:L-3-n-butylphthalide(L-NBP) can inhibit phosphorylation of tau protein and reduce the neurotoxicity of beta-amyloid peptide 1-42(Aβ_(1-42)). OBJECTIVE:To observe the neuroprotective effects of L-NBP on caspase-3 and nuclear factor kappa-B(NF-κB) expression in a rat model of Alzheimer's disease. DESIGN,TIME AND SETTING:A cell experiment was performed at the Central Laboratory of Provincial Hospital affiliated to Shandong University between January 2008 and August 2008. MATERIALS:L-NBP(purity>98%) was provided by Shijiazhuang Pharma Group NBP Pharmaceutical Company Limited.Aβ_(1-42),3-[4,5-dimethylthiazolo-2]-2,5 iphenyltetrazolium bromide(MTT),and rabbit anti-Caspase-3 polyclonal antibody were provided by Cell Signaling, USA;goat anti-choactase and rabbit anti-NF-κB antibodies were provided by Santa Cruz,USA. METHODS:Primary cultures were generated from rat basal forebrain and hippocampal neurons at 17 or 19 days of gestation.The cells were assigned into five groups:the control group,the Aβ_(1-42) group(2μmol/ L),the Aβ_(1-42) + 0.1μmol/L L-NBP group,the Aβ_(1-42)+ 1μmol/L L-NBP group,and the Aβ_(1-42)+ 10μmol/L L-NBP group.The neurons were treated with Aβ_(1-42)(2μmol/L) alone or in combination with L-NBP(0.1,1,10μmol/L) for 48 hours.Cells in the control group were incubated in PBS. MAIN OUTCOME MEASURES:Morphologic changes were evaluated using inverted microscopy, viability using the MTT method,and the changes in caspase-3 and NF-κB expression using Western blot. RESULTS:Induction with Aβ_(1-42) for 48 hours caused cell death and soma atrophy,and increased caspase-3 and NF-κB expression(P<0.05).L-NBP blocked these changes in cell morphology, decreased caspase-3 and NF-κB expression(P<0.05),and improved cell viability,especially at the high dose(P<0.05). CONCLUSION:Aβ_(1-42) is toxic to basal forebrain and hippocampal primary neurons;L-NBP protects against this toxicity and inhibits the induction of caspase-3 and NF-κB expression. | Ruixia Wang Yong Zhang Liangliang Jiang Guozhao Ma Qingxi Fu Jialong Li Peng Yan Lunqian Shen Yabo Feng Chunxia Li Zaiying Pang Yuanxiao Cui Chunfu Chen Yifeng Du Zhaokong Liu | 2009 | Neural Regeneration Research2009，4，4： | 3 |
| 6 | A Phase Change Memory Chip Based on Ti Sb Te Alloy in 40-nm Standard CMOS Technology显示文摘In this letter, a phase change random access memory(PCRAM) chip based on Ti0.4Sb2Te3 alloy material was fabricated in a 40-nm 4-metal level complementary metal-oxide semiconductor(CMOS) technology. The phase change resistor was then integrated after CMOS logic fabrication. The PCRAM was successfully embedded without changing any logic device and process, in which 1.1 V negative-channel metal-oxide semiconductor device was used as the memory cell selector. The currents and the time of SET and RESET operations were found to be 0.2 and 0.5 m A, 100 and 10 ns,respectively. The high speed performance of this chip may highlight the design advantages in many embedded applications. | Zhitang Song Yi Peng Zhan Daolin Cai Bo Liu Yifeng Chen Jiadong Ren | 2015 | Nano-Micro Letters2015，7，2： | 2 |
| 7 | The promoting effect of low-level sulfidation in PdCuS nanoparticles catalyzed alkyne semihydrogenation显示文摘硫来源的支持的效果是吸引人却糟糕听说的现象。此处,我们与硫粉末的不同数量学习了 PdCu 二金属的 nanoparticles (NP ) 的处理。低级 sulfidation 导致了由表面组成的 Pd30Cu10S9 NP 催化剂的产生充实的 Pd NP,电子缺乏的 Pd 和 Cu,以及零原子价硫。Pd30Cu10S9 NP 催化剂在炔属羟的 semihydrogenation 显示出显着地提高的活动和选择。我们的学习第一次在原子水平为硫的支持的效果揭示了一个可能的原因,建议在催化剂设计的新策略。 | Cai Wu Yifeng Chen Rongan Shen Wei Zhu Yue Gong Lin Gu Qing Peng Huifang Guo Wei He | 2018 | Nano Research2018，11，9： | 2 |
| 8 | A glutathione activatable pro-drug-photosensitizer for combined chemotherapy and photodynamic therapy显示文摘During cancer treatment,chemotherapeutic drugs always result in severe side-effects and drug resistance.Therefore,combining cheomtherapy with other therapeutic modalities,such as photodynamic therapy(PDT)and designing an activable platform is promising for precise and efficient anticancer treatment.Herein,we report a“pro-drug-photosensitizer”agent,LMB-S-CPT,bearing a disulfide bond as the glutathione(GSH)-activatable linker.LMB-S-CPT can be selectively activated by GSH to release activated drug,camptothecin(CPT),for chemotherapy and activated photosensitizer,methylene blue(MB),for PDT.LMB-S-CPT exhibits excellent tumor-activatable performance when injected into tumor-bearing mice,as well as specific cancer therapy with negligible toxic side effects.The activatable pro-drug-photosensitizer offers a new strategy for chemo-photodynamic therapy and displays precise,selective and excellent antitumor effect. | Yanjun Yang Yifeng Zhang Ran Wang Xiang Rong Ting Liu Xiang Xia Jiangli Fan Wen Sun Xiaojun Peng | 2022 | Chinese Chemical Letters2022，33，10： | 2 |
| 9 | Bimetallic PdCo catalyst for selective direct formylation of amines by carbon monoxide显示文摘高度有效、选择的二金属的 Pd 0.88 公司 0.12 nanoparticle 催化剂被碳一氧化物为胺的直接 N-formylation 开发。这催化剂与大量底层兼容,负担得起在实际、温和的反应条件下面的各种各样的综合地有用的 formamides。 | Yifeng Chen Junjie Mao Rongan Shen Dingsheng Wang Qing Peng Zhixin Yu Huifang Guo Wei He | 2017 | Nano Research2017，10，3： | 2 |
| 10 | Expression of miR-150 and miR-3940-5p is reduced in non-small cell lungcarcinoma and correlates with clinicopathological features显示文摘 | Yifeng Sun Bo Su Peng Zhang Huikang Xie Hui Zheng Yongjie Xu Qiaoling Du Huan Zeng Xiao Zhou Chang Chen Wen Gao | 2013 | Oncology Reports2013，，2： | 1 |
| 11 | Self-anti-angiogenesis nanoparticles enhance anti-metastatic-tumor efficacy of chemotherapeutics显示文摘Beyond traditional endothelium-dependent vessel(EDV),vascular mimicry(VM)is another critical tumor angiogenesis that further forms in many malignant metastatic tumors.However,the existing anti-angiogenesis combined chemotherapeutics strategies are only efficient for the treatment of EDV-based subcutaneous tumors,but remain a great challenge for the treatment of in situ malignant metastatic tumor associated with EDV and VM.Here,we demonstrate a self-assembled nanoparticle(VE-DDP-Pro)featuring self-anti-EDV and-VM capacity enables to significantly enhance the treatment efficacy of cisplatin(DDP)against the growth and metastasis of ovarian cancer.The VE-DDP-Pro is constructed by patching DDP loaded cRGD-folate-heparin nanoparticles(VE)onto the surface of protamine(Pro)nanoparticle.We demonstrated the self-anti-angiogenesis capacity of VE-DDP-Pro was attributed to VE,which could significantly inhibit the formation of EDV and VM by regulating signaling pathway of MMP-2/VEGF,AKT/mTOR/MMP-2/Laminin and AKT/mTOR/EMT,facilitating chemotherapeutics to effectively suppress the development and metastasis of ovarian cancer.Thus,combing with the chemotherapeutics effectiveness of DDP,the VE-DDP-Pro can significantly enhance treatment efficacy and prolong median survival of mice with metastatic ovarian cancer.We believe our self-assembled nanoparticles integrating the anti-EDV and anti-VM capacity provide a new preclinical sight to enhance the efficacy of chemotherapeutics for the treatment malignant metastasis tumor. | Jiamao Luo Xinxian Zhong Yingming Peng Chenyuan Hao Xiaomei Liang Yulu Yang Xiubo Shi Xuncai Chen Xiao Yi iaoxuan Li Jianhua Wu Jinheng Li Qian Xiao Chentian Wu b Ruojing Lu b Yao Pan Xuejiao Wang Jun-Bing Fan Yifeng Wang Ying Wang | 2022 | Bioactive Materials2022，7，7： | 1 |
| 12 | A precipitate-free AlCoFeNi eutectic high-entropy alloy with strong strain hardening显示文摘Over recent years,eutectic high-entropy alloys(EHEAs)have intrigued substantial research enthusiasms due to their good castability as well as balanced strength-ductility synergy.In this study,a bulk cast Al_(19.25)Co_(18.86)Fe_(18.36)Ni_(43.53)EHEA is developed with fine in-situ lamellar eutectics.The eutectics comprise alternating ordered face-centered-cubic(L1_(2))and ordered body-centered-cubic(B2)phases with semicoherent interfaces.The resulting microstructure resembles that of most reported as-cast EHEAs,but the B2 lamellae are devoid of nano-precipitates because of the Cr-element removal in current tailored eutectic composition.Surprisingly,the B2 lamellae still feature much higher deformation resistance than the L1_(2) lamellae,so that less lattice defects are detected in the B2 lamellae until the fracture.More interestingly,in the L1_(2) lamellae we identify a dynamic microstructure refinement that correlates to extraordinary strain hardening in tension.The precipitate-free EHEA consequently shows excellent tensile ductility of~10%and high ultimate strength up to~956 MPa. | Peijian Shi Yi Li Yuebo Wen Yiqi Li Yan Wang Weili Ren Tianxiang Zheng Yifeng Guo Long Hou Zhe Shen Ying Jiang Jianchao Peng Pengfei Hu Ningning Liang Qingdong Liu Peter K.Liaw Yunbo Zhong | 2021 | Journal of Materials Science & Technology2021，，30： | 1 |
| 13 | Study on the preparation of Mn-Zn soft magnetic ferrite powders from waste Zn-Mn dry batteries显示文摘 | PENG Changhong BAI Benshuai CHEN Yifeng | 2008 | Waste Manage2008，28，： | 1 |
| 14 | A paradigm for high-throughput screening of cell-selective surfaces coupling orthogonal gradients and machine learning-based cell recognition显示文摘The combinational density of immobilized functional molecules on biomaterial surfaces directs cell behaviors. However, limited by the low efficiency of traditional low-throughput experimental methods, investigation and optimization of the combinational density remain daunting challenges. Herein, we report a high-throughput screening set-up to study biomaterial surface functionalization by integrating photo-controlled thiol-ene surface chemistry and machine learning-based label-free cell identification and statistics. Through such a strategy, a specific surface combinational density of polyethylene glycol (PEG) and arginine-glutamic acid-aspartic acid-valine peptide (REDV) leads to high endothelial cell (EC) selectivity against smooth muscle cell (SMC) was identified. The composition was translated as a coating formula to modify medical nickel-titanium alloy surfaces, which was then proved to improve EC competitiveness and induce endothelialization. This work provided a high-throughput method to investigate behaviors of co-cultured cells on biomaterial surfaces modified with combinatorial functional molecules. | Hongye Hao Yunfan Xue Yuhui Wu Cong Wang Yifeng Chen Xingwang Wang Peng Zhang Jian Ji | 2023 | Bioactive Materials2023，，10： | 1 |
| 15 | Thermoelectric enhancement of p-type Si_(80)Ge_(20) alloy via co-compositing of dual oxides:Respective regulation for power factor and thermal conductivity byβ-Ga_(2)O_(3) and SiO_(2) aerogel powders显示文摘Si-based thermoelectric(TE)materials are exhibiting remarkable perspectives in self-energized applications with their special advantages.However,the relatively high total thermal conductivity(κ)prevents their TE enhancement.Here,a strategy of co-compositing dual oxides was implemented for enhancing the TE properties of p-type Si_(80)Ge_(20) bulks.Composited Ga2O_(3) was demonstrated to enhance the power factor(PF)due to the crystallization-induced effect of produced Ga by decomposition on SiGe matrix.Associating with compositing SiO_(2) aerogel(a-SiO_(2))powder,not only introduced the fine amorphous inclusions and decreased the grain size of host matrix,but also various nano morphologies were formed,i.e.,nano inclusions,precipitations,twin boundaries(TBs),and faults.Combining with the eutectic Ge,hierarchical scattering centers impeded the phonon transport comprehensively(decreasing the phonon group velocity(a v)and relaxation time)for reducing the lattice-induced thermal conductivity(lκ).As a result,a minimumκof 2.38 W·m^(−1)·K^(−1) was achieved,which is significantly dropped by 32.6%in contrast with that of the pristine counterpart.Ultimately,a maximal dimensionless figure of merit(ZT)of 0.9 was achieved at 600℃,which is better than those of most corresponding oxide-composited Si-based bulks. | Huajun LAI Ying PENG Mengfei WANG Runze SHI Junliang CHEN Chengyan LIU Yifeng WANG Lei MIAO Haiqiao WEI | 2023 | Journal of Advanced Ceramics2023，12，2： | 1 |
| 16 | Heat transfer characteristics of refrigerant-based nanofluids low boiling inside a horizontal smooth tube显示文摘 | Peng Hao Ding Guoliang Jiang Weiting Hu Haitao Gao Yifeng | 2009 | International Journal of Refrigeration2009，32，6： | 1 |
| 17 | Heat transfer characteristics of refrigerant-based nanofluid flow boiling inside a horizontal smooth tube 显示文摘 | Peng Hao Ding Guoliang Jiang Weiting Hu Haitao Gao Yifeng | 2009 | International Journal of Refrigeration2009，32，6： | 1 |
| 18 | Measurement and correlation of frictional pressure drop of refrigerant-based nanofluid flow boiling inside a horizontal smooth tube 显示文摘 | Peng Hao Ding Guoliang Jiang Weiting Hu Haitao Gao Yifeng | 2009 | International Journal of Refrigeration2009，32，6： | 1 |
| 19 | Does practice make perfect? Results from a Chinese feasibility study of cognitive remediation in schizophrenia显示文摘 | LindaK Byrne Daihui Peng Marita McCabe David Mellor Jie Zhang Tianhong Zhang Jia Huang Yifeng Xu | 2013 | Neuropsychological Rehabilitation2013，，4： | 1 |
| 20 | A Novel Weightedgraph-based Grouping Algorithm for Metadata Prefetching显示文摘 | Gu Peng Wang Jun Zhu Yifeng | 2010 | IEEE Transactions on Computers2010，59，1： | 1 |
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