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| 1 | Fast-moving target tracking based on mean shift and frame-difference methods显示文摘The mean shift tracker has difficulty in tracking fast moving targets and suffers from tracking error accumulation problem.To overcome the limitations of the mean shift method,a new approach is proposed by integrating the mean shift algorithm and frame-difference methods.The rough position of the moving target is first located by the direct frame-difference algorithm and three-frame-difference algorithm for the immobile camera scenes and mobile camera scenes,respectively.Then,the mean shift algorithm is used to achieve precise tracking of the target.Several tracking experiments show that the proposed method can effectively track first moving targets and overcome the tracking error accumulation problem. | Hongpeng Yin Yi Chai Simon X. Yang Xiaoyan Yang | 2011 | Journal of Systems Engineering and Electronics2011，22，4： | 31 |
| 2 | Ambient volatile organic compounds pollution in China显示文摘Owing to rapid economic and industrial development,China has been suffering from degraded air quality and visibility. Volatile organic compounds(VOCs)are important precursors to the formation of ground-level ozone and hence photochemical smog. Some VOCs adversely affect human health. Therefore,VOCs have recently elicited public concern and given new impetus to scientific interest. China is now implementing a series of polices to control VOCs pollution. The key to formulating policy is understanding the ambient VOCs pollution status. This paper mainly analyzes the species,levels,sources,and spatial distributions of VOCs in ambient air. The results show that the concentrations of ambient VOCs in China are much higher than those of developed countries such as the United States and Japan,especial benzene,which exceeds available standards. At the same time,the ozone formation potential(OFP)and secondary organic aerosol formation potential(SOAFP)of various VOCs are calculated. Aromatics and alkenes have much higher OFPs,while aromatics have higher SOAFP. The OFPs of ambient VOCs in the cities of Beijing,Guangzhou and Changchun are very high,and the SOAFP of ambient VOCs in the cities of Hangzhou,Guangzhou and Changchun are higher. | Xinmin Zhang Zhigang Xue Hong Li Li Yan Yuan Yang Yi Wang Jingchun Duan Lei Li Fahe Chai Miaomiao Cheng Weiqi Zhang | 2017 | Journal of Environmental Sciences2017，29，5： | 34 |
| 3 | Genome-wide Identification and Classification of HSF Family in Grape, and Their Transcriptional Analysis under Heat Acclimation and Heat Stress显示文摘Heat stress is one of the most serious threats in viticulture. Heat shock transcription factors(HSFs) have been proven to be the most important transcriptional factor family in the plant response to heat. In this study, a total of 19 putative HSF genes(VHSFs) were identified from the 12 × Vitis vinifera Pinot Noir PN4002 genome, and their chromosomal location, phylogenetic tree, exon-intron structure and conserved motifs were also analyzed. In addition, these HSFs transcriptional profiles in Vitis vinifera 'Jingxiu'(weak heat tolerance) and Vitis davidii 'Tangwei'(strong heat tolerance) under heat stress(47℃) and heat acclimation(38℃) were presented. Only VHSF01, VHSF05, VHSF15 and VHSF18 among 19 VHSFs showed different transcriptional models in these two genotypes under the same treatment, suggesting that these four VHSFs may be important factors which result in a thermotolerance difference between 'Jingxiu' and 'Tangwei'. This study provides novel insights into the response of 19 VHSFs to heat stress in the grape and suggests that potential key VHSFs in grape thermotolerance have great implications for molecular breeding in grapes. | LIU Guotian CHAI Fengmei WANG Yi JIANG Jinzhu DUAN Wei WANG Yuting WANG Fangfang LI Shaohua WANG Lijun | 2018 | Horticultural Plant Journal2018，4，4： | 13 |
| 4 | Core-shell Au@MnO2 nanoparticles for enhanced radiotherapy via improving the tumor oxygenation显示文摘在稳固的肿瘤的本地组织缺氧经常导致抵抗到放射疗法(RT ) ,在哪个氧为提高 DNA 损坏的一个必要元素被电离引起放射。此处,我们开发了 gold@manganese 二氧化物(有聚乙烯乙二醇(木钉) 的 Au@MnO 2) 核心壳 nanoparticles 是的涂层在癌症治疗期间改进 RT 功效的一个新奇 radiosensitizing 代理人。在这 Au@MnO 2 nanostructure ,当金核心是著名 RT 时,交往与的 sensitizer X光检查为在 RT 下面杀死的改进癌症生产控告的粒子, MnO 2壳可以触发内长的 H 2在肿瘤微型环境到的 O 2产生氧并且克服 hypoxiaassociated RT 抵抗。是示威了由在 vitro 并且在 vivo 实验, Au@MnO 2-PEG nanoparticles 充当了有效 radiosensitizers 显著地在 RT 期间提高癌症治疗功效。而且, Au@MnO 2-PEG 的明显的副作用都没在老鼠被观察。因此,我们的工作为 hypoxic 肿瘤的提高的 RT 治疗与潜力介绍 radiosensitizer 的一种新类型。 | Xuan Yi Lei Chen Xiaoyan Zhong Roulin Gao Yitao Qian Fan Wu Guosheng Song Zhifang Chai Zhuang Liu Kai Yang | 2016 | Nano Research2016，9，11： | 12 |
| 5 | Structural basis of anti-PD-L1 monoclonal antibody avelumab for tumor therapy显示文摘 | Kefang Liu ShuguangTan Yan Chai Danqing Chen Hao Song Catherine Wei-Hong Zhang yi Shi Jun Liu Wenjie Tan Jianxin Lyu Shah Gao Jinghua Yan Jianxun Qi George F Gao | 2017 | Cell Research2017，27，1： | 11 |
| 6 | A survey on distributed compressed sensing: theory and applications显示文摘 | Hongpeng YIN Jinxing LI Yi CHAI Simon X. YANG | 2014 | Frontiers of Computer Science2014，8，6： | 10 |
| 7 | Intelligent Manufacturing for the Process Industry Driven by Industrial Artificial Intelligence显示文摘Based on the analysis of the characteristics and operation status of the process industry,as well as the development of the global intelligent manufacturing industry,a new mode of intelligent manufacturing for the process industry,namely,deep integration of industrial artificial intelligence and the Industrial Internet with the process industry,is proposed.This paper analyzes the development status of the existing three-tier structure of the process industry,which consists of the enterprise resource planning,the manufacturing execution system,and the process control system,and examines the decision-making,control,and operation management adopted by process enterprises.Based on this analysis,it then describes the meaning of an intelligent manufacturing framework and presents a vision of an intelligent optimal decision-making system based on human–machine cooperation and an intelligent autonomous control system.Finally,this paper analyzes the scientific challenges and key technologies that are crucial for the successful deployment of intelligent manufacturing in the process industry. | Tao Yang Xinlei Yi Shaowen Lu Karl HJohansson Tianyou Chai | 2021 | Engineering2021，7，9： | 8 |
| 8 | H2 strain attenuated live hepatitis A vaccines:protective efficacy in a hepatitis A outbreak显示文摘AIM To investigate the protective efficacy ofH2 strain attenuated live hepatitis A vaccines(H2-strain vaccines)in hepatitis A(HA)outbreaks.METHODS With the permission of theirparents,5551 pre-school and grade 1-3 primaryschool children were inoculated with 1 dose(106.5TCID50)of H2-strain vaccines in anonrandomized,controlled trial conducted inFucheng County,Hebei Province in May 1997.Another 6485 children in the same grades andcompatible in gender and age were enrolled ascontrols.Epidemiological and serological surveywas conducted to evaluate the protectiveefficacy of the vaccines.ELISA was used todetect serum IgM anti-HAV.RESULTS HA outbreak started in early May1998,peaked in the middle of the same month,and lasted about 80 days.Overall 302 HA caseswere found,192(53.58%)were 5-9 years old.One vaccinee and 25 control cases were found tohave hepatitis A,which account for 0.28%(1/356)and 5.92%(25/422)of all vaccinees andcontrols in the 14 villages,respectively.The protective efficacy of vaccines was 95.27%(95% Cl:85.83%-104.72%).In subjects testedfor anti-HAV IgM from 13 villages,1(0.40%)overt and 11(4.06%)asymptomatic HAV caseswere found in 271 vaccinees,but 21(6.69%)ofovert and asymptomatic ones were found in 314controls.CONCLUSION H2 strain vaccines were excellent in preventing overt hepatitis A, but not so effective in preventing asymptomatic hepatitis A virus infection. A booster dose might be needed to get permanent reliable immunity. | Yu Liang Zhao Zong Da Meng Zhi Yi Xu Jun Jie Guo Shao Ai Chai Cheng Gang Duo Xuan Yi Wang Jin Feng Yao Hong Bin Liu Shun Xiang Qi Hui Bin Zhu | 2000 | World Journal of Gastroenterology2000，6，6： | 7 |
| 9 | Mycobacterium tuberculosis Mce2E suppresses the macrophage innate immune response and promotes epithelial cell proliferation显示文摘The intracellular pathogen Mycobacterium tuberculosis(Mtb)can survive in the host and cause disease by interfering with a variety of cellular functions.The mammalian cell entry 2(mce2)operon of Mtb has been shown to contribute to tuberculosis pathogenicity.However,little is known about the regulatory roles of Mtb Mce2 family proteins towards host cellular functions.Here we show that the Mce2 family protein Mce2E suppressed the macrophage innate immune response and promoted epithelial cell proliferation.Mce2E inhibited activation of the extracellular signal-regulated kinase(ERK)and Jun N-terminal kinase(JNK)mitogen-activated protein kinase(MAPK)signaling pathways in a non-canonical D motif(a MAPK-docking motif)-dependent manner,leading to reduced expression of TNF and IL-6 in macrophages.Furthermore,Mce2E promoted proliferation of human lung epithelium-derived lung adenoma A549 cells by inhibiting K48-linked polyubiquitination of eEF1A1 in aβstrand region-dependent manner.In summary,Mce2E is a novel multifunctional Mtb virulence factor that regulates host cellular functions in a niche-dependent manner.Our data suggest a potential novel target for TB therapy. | Lihua Qiang Jing Wang Yong Zhang Pupu Ge Qiyao Chai Bingxi Li Yi Shi Lingqiang Zhang George Fu Gao Cui Hua Liu | 2019 | Cellular & Molecular Immunology2019，16，4： | 7 |
| 10 | Analysis of Review Helpfulness Based on Consumer Perspective显示文摘When consumers make purchase decisions, they generally refer to the reviews generated by other consumers who have already purchased similar products in order to get more information. Online transaction platforms provide a highly convenient channel for consumers to generate and retrieve product reviews. In addition,consumers can also vote reviews perceived to be helpful in making their decision. However, due to diverse characteristics, consumers can have different preferences on products and reviews. Their voting behavior can be influenced by reviews and existing review votes. To explore the influence mechanism of the reviewer, the review,and the existing votes on review helpfulness, we propose three hypotheses based on the consumer perspective and perform statistical tests to verify these hypotheses with real review data from Amazon. Our empirical study indicates that review helpfulness has significant correlation and trend with reviewers, review valance, and review votes. In this paper, we also discuss the implications of our findings on consumer preference and review helpfulness. | Yuanlin Chen Yueting Chai Yi Liu Yang Xu | 2015 | Tsinghua Science and Technology2015，20，3： | 6 |
| 11 | Association between polymorphism rs6983267 and gastric cancer risk in Chinese population显示文摘AIM: To explore the association between single nucleotide polymorphisms (SNPs) at 8q24 and gastric cancer risk. METHODS: A case-control investigation including 212 gastric cancer patients and 377 healthy controls was conducted. The genotypes of SNPs (rs6983267, rs7008482 and rs10808555) were examined and established through polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP). Multivariate logistic regression models were used to evaluate the association between SNPs and gastric cancer. RESULTS: The genotype frequencies of rs6983267 in gastric cancer patients were obviously different from those in the control (P = 0.005). GT genotype of rs6983267 was associated with an increased risk of gastric cancer compared with GG genotype (adjusted odds ratio = 2.01, 95% confidence interval: 1.28-3.14). Further stratified analysis indicated that rs6983267 GT genotype facilitated the risk of gastric cancer of non-cardiac and intestinal type (OR: 2.638, 95% CI: 1.464-4.753; OR: 1.916, 95% CI: 1.166-3.150, respectively). CONCLUSION: This study demonstrates for the first time that rs6983267 is involved in susceptibility to gastric cancer, although further large-sample investigations are still needed. | Yi Guo Jing Fang Yan Liu Hai-Hui Sheng Xiao-Yan Zhang Hai-Na Chai Wei jin Ke-Hao Zhang Chang-Qing Yang Heng-jun Gao | 2011 | World Journal of Gastroenterology2011，17，13： | 5 |
| 12 | Notch signaling in the differentiation of MEE cells from the developing mouse palate显示文摘 | Yanping Zhang Jixia Chai Yi Qiu Meihua Zhang Lihong Zhang Jianchun Yu | 2014 | Acta Biochimica et Biophysica Sinica2014，46，4： | 5 |
| 13 | Three new sesquiterpene alkaloids from the root of Tripterygium wilfordii显示文摘三新 sesquiterpene 碱, 1-desacetylwilforgine (1 ) , 1-desacetylwilforine (2 ) ,和 9 鈥 ? hydroxy-2-nicotinoylwilforine (3 ) 从 Tripterygium wilfordii 钩 f. 的根被孤立,与六已知的碱一起。他们的结构被建立根据光谱分析。 | Chun Min Wu Lin Mei Zhou Yi Feng Chai Yu Tian Wu Guo Rong Fan | 2010 | Chinese Chemical Letters2010，21，7： | 4 |
| 14 | Characterization of the Hot Deformation Behavior of Cu–Cr–Zr Alloy by Processing Maps显示文摘Hot deformation behavior of the Cu–Cr–Zr alloy was investigated using hot compressive tests in the temperature range of 650–850 °C and strain rate range of 0.001–10 s-1. The constitutive equation of the alloy based on the hyperbolic-sine equation was established to characterize the flow stress as a function of strain rate and deformation temperature. The critical conditions for the occurrence of dynamic recrystallization were determined based on the alloy strain hardening rate curves. Based on the dynamic material model, the processing maps at the strains of 0.3, 0.4 and 0.5were obtained. When the true strain was 0.5, greater power dissipation efficiency was observed at 800–850 °C and under0.001–0.1 s-1, with the peak efficiency of 47%. The evolution of DRX microstructure strongly depends on the deformation temperature and the strain rate. Based on the processing maps and microstructure evolution, the optimal hot working conditions for the Cu–Cr–Zr alloy are in the temperature range of 800–850 °C and the strain rate range of 0.001–0.1 s-1. | Yi Zhang Hui-Li Sun Alex A.Volinsky Bao-Hong Tian Zhe Chai Ping Liu Yong Liu | 2016 | Acta Metallurgica Sinica(English Letters)2016，29，5： | 3 |
| 15 | Aligned fibrin/functionalized self-assembling peptide interpenetrating nanofiber hydrogel presenting multi-cues promotes peripheral nerve functional recovery显示文摘Nerve guidance conduits with hollow lumen fail to regenerate critical-sized peripheral nerve defects(15 mm in rats and 25 mm in humans),which can be improved by a beneficial intraluminal microenvironment.However,individual cues provided by intraluminal filling materials are inadequate to eliminate the functional gap between regenerated nerves and normal nerves.Herein,an aligned fibrin/functionalized self-assembling peptide(AFG/fSAP)interpenetrating nanofiber hydrogel that exerting synergistic topographical and biochemical cues for peripheral nerve regeneration is constructed via electrospinning and molecular self-assembly.The hydrogel possesses an aligned structure,high water content,appropriate mechanical properties and suitable biodegradation capabilities for nerve repair,which enhances the alignment and neurotrophin secretion of primary Schwann cells(SCs)in vitro,and successfully bridges a 15-mm sciatic nerve gap in rats in vivo.The rats transplanted with the AFG/fSAP hydrogel exhibit satisfactory morphological and functional recovery in myelinated nerve fibers and innervated muscles.The motor function recovery facilitated by the AFG/fSAP hydrogel is comparable with that of autografts.Moreover,the AFG/fSAP hydrogel upregulates the regeneration-associated gene expression and activates the PI3K/Akt and MAPK signaling pathways in the regenerated nerve.Altogether,the AFG/fSAP hydrogel represents a promising approach for peripheral nerve repair through an integration of structural guidance and biochemical stimulation. | Shuhui Yang Jinjin Zhu Changfeng Lu Yi Chai Zheng Cao Jiaju Lu Zhe Zhang He Zhao Yin-Yuan Huang Shenglian Yao Xiangdong Kong Peixun Zhang Xiumei Wang | 2022 | Bioactive Materials2022，7，2： | 3 |
| 16 | Alternate binding modes of anti-CRISPR viral suppressors AcrF1/2 to Csy surveillance complex revealed by cryo-EM structures显示文摘抗菌素编码 anti-CRISPR suppressors 抵抗他们的细菌的主人的 CRISPR/Cas 免疫,因此便于他们的幸存和复制。以前的研究显示出那二编码噬菌体的 anti-CRISPR 蛋白质, AcrF1 和 AcrF2,如果由由 Csy 监视建筑群阻止目标 DNA 识别的 Pseudomonas aeruginosa 的 CRISPR/Cas 系统,而是精确位于下面机制是未知的,压制类型。这里我们在场 Csy 建筑群一定的 AcrF1/2 的结构由 cryo 他们决定了单个粒子的重建。由结构的分析,我们发现 AcrF1 由防碍在 DNA 目标海滨和 crRNA 分隔符之间的基础配对禁止 Csy 建筑群的目标 DNA 识别。另外,当个别地工作或与 AcrF2 合作时, AcrF1 的多重拷贝与不同模式绑在 Csy 建筑群,它可能排除通过不同机制有约束力的目标 DNA。和以前的报告,我们为二 anti-CRISPR suppressors, AcrF1 和 AcrF2 提供一种全面工作情形,它由指向 Csy 监视建筑群的沉默 CRISPR/Cas 免疫。 | Ruchao Peng Ying Xu Tengfei Zhu Ningning Li Jianxun Qi Yan Chai Min Wu Xinzheng Zhang Yi Shi Peiyi Wang Jiawei Wang Ning Gao George Fu Gao | 2017 | Cell Research2017，27，7： | 3 |
| 17 | Exo-celiac liver in Glyptosternum maculatum显示文摘A unique structure in the fish of Glyptosternum maculatum(Regan)(Siluriformes:Sisoridae)is reported.It was identified as a part of the liver named 'exo-celiac liver'.This new organ is located between skin and muscle and connected with the celiac liver by a funiform tissue,'joint belt'.It has similar histological features and isozyme electrophoretogramic bands of lactate dehydrogenase,esterase,malate dehydrogenase and alcohol dehydrogenase as in the celiac liver.This unique organ has biological research value and could serve as an important tool for studying organogenesis and evolution. | Li Hongjing Xie Congxin Li Dapeng Chai Yi Liu Hongyan Fan Qixue Zhu Bangke | 2007 | Progress in Natural Science:Materials International2007，17，9： | 3 |
| 18 | A novel kind of sufficient conditions for safety judgement based on control barrier function显示文摘Dear editor,Recently, work safety accidents have started to occur on a large scale in Chinese petrochemical companies. Further,the operational safety of large and complex systems is being closely monitored by our government, environmental organizations,and conscientious citizens. | Zheren ZHU Yi CHAI Zhimin YANG | 2021 | Science China(Information Sciences)2021，64，9： | 3 |
| 19 | A Primal-Dual SGD Algorithm for Distributed Nonconvex Optimization显示文摘The distributed nonconvex optimization problem of minimizing a global cost function formed by a sum of n local cost functions by using local information exchange is considered.This problem is an important component of many machine learning techniques with data parallelism,such as deep learning and federated learning.We propose a distributed primal-dual stochastic gradient descent(SGD)algorithm,suitable for arbitrarily connected communication networks and any smooth(possibly nonconvex)cost functions.We show that the proposed algorithm achieves the linear speedup convergence rate O(1/(√nT))for general nonconvex cost functions and the linear speedup convergence rate O(1/(nT)) when the global cost function satisfies the Polyak-Lojasiewicz(P-L)condition,where T is the total number of iterations.We also show that the output of the proposed algorithm with constant parameters linearly converges to a neighborhood of a global optimum.We demonstrate through numerical experiments the efficiency of our algorithm in comparison with the baseline centralized SGD and recently proposed distributed SGD algorithms. | Xinlei Yi Shengjun Zhang Tao Yang Tianyou Chai Karl Henrik Johansson | 2022 | IEEE/CAA Journal of Automatica Sinica2022，9，5： | 3 |
| 20 | Clinical Experience with Primary Hepatic Epithelioid Hemangioendothelioma: Retrospective Study of 33 Patients显示文摘 | Long-Rong Wang Jia-Min Zhou Yi-Ming Zhao Hong-Wei He Zong-Tao Chai Miao Wang Yuan Ji Yi Chen Chen Liu Hui-Chuan Sun Wei-Zhong Wu Qing-Hai Ye Jian Zhou Jia Fan Zhao-You Tang Lu Wang | 2012 | World Journal of Surgery2012，，11： | 3 |
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