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| 1 | Transmission Dynamics of an Outbreak of the COVID-19 Delta Variant B.1.617.2——Guangdong Province,China,May-June 2021显示文摘On May 21,2021,a local case of coronavirus disease 2019(COVID-19)was confirmed in a 75-year-old woman(experienced onset of symptoms on May 18)in Liwan District,Guangzhou City,Guangdong Province,China.The number of infections has increased in the following 10 days and led to 5 generations of transmission. | Meng Zhang Jianpeng Xiao Aiping Deng Yingtao Zhang Yali Zhuang Ting Hu Jiansen Li Hongwei Tu Bosheng Li Yan Zhou Jun Yuan Lei Luo Zimian Liang Youzhi Huang Guoqiang Ye Mingwei Cai Gongli Li Bo Yang Bin Xu Ximing Huang Yazun Cui Dongsheng Ren Yanping Zhang Min Kang Yan Li | 2021 | China CDC weekly2021，3，27： | 51 |
| 2 | Reproductive management through integration of PGD and MPS-based noninvasive prenatal screening/diagnosis for a family with GJB2-associated hearing impairment显示文摘A couple with a proband child of GJB2(encoding the gap junction protein connexin 26)-associated hearing impairment and a previous pregnancy miscarriage sought for a reproductive solution to bear a healthy child. Our study aimed to develop a customized preconception-to-neonate care trajectory to fulfill this clinical demand by integrating preimplantation genetic diagnosis(PGD), noninvasive prenatal testing(NIPT), and noninvasive prenatal diagnosis(NIPD) into the strategy. Auditory and genetic diagnosis of the proband child was carried out to identify the disease causative mutations. The couple then received in-vitro-fertilization treatment, and eight embryos were obtained for day 5 biopsy. PGD was performed by short-tandem-repeat linkage analysis and Sanger sequencing of GJB2 gene. Transfer of a GJB2 c.235del C heterozygous embryo resulted in a singleton pregnancy. At the 13 th week of gestation, genomic DNA(g DNA) from the trio family and cell-free DNA(cf DNA) from maternal plasma were obtained for assessment of fetal chromosomal aneuploidy and GJB2 mutations. NIPT and NIPD showed the absence of chromosomal aneuploidy and GJB2-associated disease in the fetus, which was later confirmed by invasive procedures and postnatal genetic/auditory diagnosis. This strategy successfully prevented the transmission of hearing impairment in the newborn, thus providing a valuable experience in reproductive management of similar cases and potentially other monogenic disorders. | XIONG WenPing WANG DaYong GAO Yuan GAO Ya WANG HongYang GUAN Jing LAN Lan YAN JunHao ZONG Liang YUAN Yuan DONG Wei HUANG SeXin WU KeLiang WANG YaoShen WANG ZhiLi PENG HongMei LU YanPing XIE LinYi ZHAO Cui WANG Li ZHANG QiuJing GAO Yun LI Na YANG Ju YIN ZiFang HAN Bing WANG Wei CHEN Zi-Jiang WANG QiuJu | 2015 | Science China(Life Sciences)2015，58，9： | 12 |
| 3 | Wheat straw pretreatment with KOH for enhancing biomethane production and fertilizer value in anaerobic digestion显示文摘Wheat straw biodegradability during anaerobic digestion was improved by treatment with potassium hydroxide(KOH)to decrease digestion time and enhance biomethane production and fertility value.KOH concentrations of1%(K1),3%(K2),6%(K3)and 9%(K4)were tested for wheat straw pretreatment at ambient temperature with a C:N ratio of 25:1.86% of total solids(TS),89% of volatile solids(VS)and 22% of lignocellulose,cellulose and hemicellulose(LCH)(22%)were decomposed effectively with the wheat straw pretreated by 6% KOH.Enhanced biogas production and cumulative biomethane yield of 258 ml·(g VS)^(-1)were obtained increased by 45% and 41%respectively,compared with untreated wheat straw.Pretreated wheat straw digestion also yielded a digestate with higher fertilizer values potassium(138%),calcium(22%)and magnesium(16%).These results show that TS,VS and LCH can be effectively removed from wheat straw pretreated with KOH,improving biodegradability biomethane production and fertilizer value. | Muhammad Jaffar Yunzhi Pang Hairong Yuan Dexun Zou Yanping Liu Baoning Zhu Rashid Mustafa Korai Xiujin Li | 2016 | Chinese Journal of Chemical Engineering2016，24，3： | 11 |
| 4 | Identification of a novel mutation in POU3F4 for prenatal diagnosis in a Chinese family with X-linked nonsyndromic hearing loss显示文摘We present the clinical and genetic findings for a Chinese family with X-linked non-syndromic hearing loss in which the affected males showed congenital profound sensorineural hearing impairment. In two affected brothers, the computer tomography of temporal bone showed bilateral dilation of the internal auditory canal with fistulous communication between the lateral canal and the basal cochlear turn, which is consistent with the typical DFNX2 phenotype. A missense mutation (c.647G→A) in the POU3F4 gene caused a substitu- tion from glycine to glutamic acid at position 216 (p.G216E), and this mutation was found to consistently cosegregate with the deafness phenotype in the family. The mutation resulted in the loss of function of the POU3F4 by decreasing the affinity between the protein and DNA, as shown in silico by the structural analysis. Prenatal diagnosis of pregnant proband of this family revealed the c.647G→A muta- tion in DNA extracted from the amniotic fluid surrounding the fetus. The appropriate use of genetic testing and prenatal diagnosis plays a key role in reducing the recurrence of genetic defects in high-risk families. | Jianzhong Li Jing Cheng Yanping Lu Yu Lu Airing Chen YiSun Dongyang Kang Xin Zhang Pu Dai Dongyi Han Huijun Yuan | 2010 | Journal of Genetics and Genomics2010，37，12： | 9 |
| 5 | Micro-Channel Heat Sink:A Review显示文摘The method to cool a high heat flux device is an important research direction for the heat exchanger design.Micro-channels are an eflfective heat exchange structure both for single-phase and two-phase flow.In this paper,the heat transfer correlations of single-phase,two-phase and nanofluid in a micro-channel are discussed and analyzed.The correlations of pressure drop for single-phase and two-phase fluids are also presented.Excluding the different working fluids used in the micro-channel,the diameter and aspect ratio,shape and structure,surface roughness,internal and external factor and layout of micro-channel pipe are considered to analyze their influence on the heat transfer performance and pressure drop.Micro-channel technology applications include industry,air-conditioning,solar energy systems,heat pipe technology and computer data center cooling.Compared to the conventional heat exchangers used in these fields,a micro-channel heat sink showed a much better heat transfer coefficient and low volume,indicating that it is a good choice and has huge potential for cooling application.Finally,existing problems and future scopes are described,and drawing up design standard,experimental and simulated methods for evaluating its performance are the urgent actions which need to be carried out.This review paper serves as guidance for researchers to design and predict the performance of micro-channel heat sinks. | ZHOU Jinzhi CAO Xiaoling ZHANG Nan YUAN Yanping ZHAO Xudong HARDY David | 2020 | Journal of Thermal Science2020，29，6： | 9 |
| 6 | Psychological impact of the COVID-19 pandemic on healthcare workers:a cross-sectional study in China显示文摘Background Healthcare workers fighting against the coronavirus disease 2019(COVID-19)pandemic are under tremendous pressure,which puts them at an increased risk of developing psychological problems.Aims This study aimed to investigate the prevalence of psychological problems in different healthcare workers(ie,physicians,medical residents,nurses,technicians and public health professionals)during the COVID-19 pandemic in China and explore factors that are associated with the onset of psychological problems in this population during this public health crisis.Methods A cross-sectional,web-based survey was conducted in February 2020 among healthcare workers during the COVID-19 pandemic.Psychological problems were assessed using the Generalized Anxiety Disorder Scale,Patient Health Questionnaire and Insomnia Severity Index.Logistic regression analyses were used to explore the factors that were associated with psychological problems.Results The prevalence of symptoms of anxiety,depression,insomnia and the overall psychological problems in healthcare workers during the COVID-19 pandemic in China was 46.04%,44.37%,28.75%and 56.59%,respectively.The prevalence of the overall psychological problems in physicians,medical residents,nurses,technicians and public health professionals was 60.35%,50.82%,62.02%,57.54%and 62.40%,respectively.Compared with healthcare workers who did not participate in front-line work,front-line healthcare workers had a higher risk of anxiety,insomnia and overall psychological problems.In addition,attention to negative or neutral information about the pandemic,receiving negative feedback from families and friends who joined front-line work,and unwillingness to join front-line work if given a free choice were three major factors for these psychological problems.Conclusions Psychological problems are pervasive among healthcare workers during the COVID-19 pandemic.Receiving negative information and participating in front-line work appear to be.important risk factors for psychological problems.The psychological health of different healthcare workers should be protected during the COVID-19 pandemic with timely interventions and proper information feedback. | Jianyu Que Le Shi Jiahui Deng Jiajia Liu Li Zhang Suying Wu Yimiao Gong Weizhen Huang Kai Yuan Wei Yan Yankun Sun Maosheng Ran Yanping Bao Lin Lu | 2020 | General Psychiatry2020，33，3： | 8 |
| 7 | Inner Envelope CHLOROPLAST MANGANESE TRANSPORTER 1 Supports Manganese Homeostasis and Phototrophic Growth in Arabidopsis显示文摘 | Bin Zhang Chi Zhang Congge Liu Yanping Jing Yuan Wang Ling Jin Lei Yang Aigen Fu Jisen Shi Fugeng Zhao Wenzhi Lan Sheng Luan | 2018 | Molecular Plant2018，11，7： | 6 |
| 8 | Oxidation behavior of Mo-Si-B alloys at medium-to-high temperatures显示文摘Continuous exploration of high-temperature structural materials is being driven by the needs of gasturbine engines capable of withstanding the high-temperature environment.Relatively low melting points of currently applied superalloys restrain the further improvement of service tempe ratures.With higher melting tempe ratures above 2000℃,Mo-Si-B alloys are regarded as a new generation of ultrahightemperature structural materials.However,oxidation is a concern for the industrial application of Mo-Si-B alloys.Therefore,an in-depth understanding of the oxidation mechanisms may contribute to solving this issue,whereas relevant reviews about their recent advances are lacking.In the current work,a comprehensively systematic review about the oxidation behaviors of Mo-Si-B alloys is described for this purpose. | Kunming Pan Yanping Yang Shizhong Wei Honghui Wu Zhili Dong Yuan Wu Shuize Wang Laiqi Zhang Junping Lin Xinping Mao | 2021 | Journal of Materials Science & Technology2021，，1： | 5 |
| 9 | Water and Oil Resistance of Special Paperboard for Petroleum Packaging显示文摘The influence of different coating formulas and times on the water and oil resistance of paperboard was studied. The water and oil resistance of paperboard coated with a modified butadiene-styrene copolymer latex and fluorinated anion grease-proof agent was better than that coated with modified butadiene-styrene copolymer latex,where the modified butadiene-styrene copolymer latex was used as the pre-coating substrate and the F1516 fluorinated grease-proof agent was used as the top coating material. By coating modified butadiene-styrene copolymer latex with 30% solid content and F1516 fluorinated grease-proof agent with 24% solid content,the oil resistance of paperboard could reach anti-oil grade 12 and the water resistance could increased by98. 64%( compared with the base paperboard without any coating treatment). | YuJie Gao YanPing Zhang XiaoJiao Yuan LiMin Gao | 2016 | Paper And Biomaterials2016，1，1： | 4 |
| 10 | Intense broadband THz generation from femtosecond laser filamentation显示文摘Broadband and energetic terahertz (THz) pulses can be remotely generated in air through filamentation. We review such THz generation and detection in femtosecond Ti-sapphire laser induced remote filaments. New results are presented on the direct relationship between THz generation in a two color filament and induced N2 fluorescence through population trapping during molecular alignment and revival in air. This further supports the new technique of remote THz detection in air through the sensitive measurement of N2 fluorescence. | Tie-Jun Wang Shuai Yuan Yanping Chen See Leang Chin | 2013 | Chinese Optics Letters2013，11，1： | 4 |
| 11 | PhaseⅡstudy of induction chemotherapy followed by concurrent chemoradiotherapy with raltitrexed and cisplatin in locally advanced nasopharyngeal carcinoma显示文摘Objective:For locally advanced nasopharyngeal carcinoma(LA-NPC)patients,high incidences of distant metastases and severe treatment related toxicities are the main obstacles needed to be overcome.Raltitrexed,a specific thymidylate synthase inhibitor with a convenient administration schedule,has an acceptable and manageable toxicity,and possesses radio-sensitizing properties.To investigate the efficacy and safety of raltitrexed and cisplatin induction chemotherapy and concurrent chemoradiotherapy(IC+CCRT)in patients with LA-NPC,a phaseⅡclinical study was conducted.Methods:Sixty eligible patients with LA-NPC were enrolled into this study.A raltitrexed-cisplatin combination was used as part of an IC+CCRT regimen.Raltitrexed-cisplatin IC was given once every 3 weeks(q3 w)for two cycles,followed by raltitrexed-cisplatin based CCRT q3 w for two cycles.Intensity-modulated radiotherapy(IMRT)was given for all enrolled patients.Results:All patients were included in survival analysis according to the intent-to-treat principle.The objective response rate(ORR)3 months after treatment was 98%.The 2-year overall survival(OS)rate was 92%.The median relapse-free survival(RFS)time was 30.5[95%confidence interval(95%CI),28.4-32.3]months.The 2-year RFS rate was 85%.The 2-year local failure-free survival(LFFS)rate was 97%and the 2-year distant metastasis-free survival(DMFS)rate was 88%.Acute toxicities were mostly grade 2 and 3 reactions in bone marrow suppression,gastrointestinal side effect and oropharyngeal mucositis.Only two patients occurred grade 4 acute toxicities,one was bone marrow suppression and the other was dermatitis radiation.Conclusions:The combination of raltitrexed and cisplatin has a comparable efficacy to those in standard firstline therapy. | Yuan Wu Xueyan Wei Zilong Yuan Hongbin Xu Yanping Li Ying Li Liu Hu Guang Han Yu Qian Desheng Hu | 2020 | Chinese Journal of Cancer Research2020，32，5： | 4 |
| 12 | Effects of Mahuang(Herba Ephedra Sinica) and Wuweizi(Fructus Schisandrae Chinensis) medicated serum on chemotactic migration of alveolar macrophages and inters regions macrophages in rats显示文摘OBJECTIVE: To observe the effects of serum containing Mahuang(Herba Ephedra Sinica) or Wuweizi(Fructus Schisandrae Chinensis) on the migration of alveolar macrophages(AM) and interstitial macrophages(IM) from normal rats, and to analyze and compare the mechanisms leading to cell migration differences.METHODS: Rats were randomly divided into three groups: Mahuang(Herba Ephedra Sinica), Wuweizi(Fructus Schisandrae Chinensis), and blank serum. After treatment with the herbs, serum was extracted from the rats. AM and IM were isolated from normal rats and cultured. The effects of Mahuang(Herba Ephedra Sinica) and Wuweizi(Fructus Schisandrae Chinensis) medicated serum on normal rat AM and IM chemotactic migration were determined by transwell assays. The CC chemokine receptor(CCR) 2, CCR5, voltage-gated Kvl. 3 K^+channel(Kv1. 3), and voltage-gated Kvl. 5 K^+channel(Kv1. 5) protein levels were analyzed by western blotting.RESULTS: The migration quantities of AM and IM in the Mahuang(Herba Ephedra Sinica) and Wuweizi(Fructus Schisandrae Chinensis) medicated serum groups were significantly higher than those in the blank serum group(P < 0.01). Compared with the Wuweizi(Fructus Schisandrae Chinensis) medicated serum group, the migration quantity of cultured rat AM in the Mahuang(Herba Ephedra Sinica) medicated serum group was significantly increased(P <0.01). Meanwhile, compared with the Mahuang(Herba Ephedra Sinica) medicated serum group, the migration quantity of cultured rat IM in the Wuweizi(Fructus Schisandrae Chinensis) medicated serum group was significantly increased(P < 0.01).CCR2, CCR5, Kv1. 3, and Kv1. 5 proteins were expressed on the AM cell surface, and showed significantly higher expression in the Mahuang(Herba Ephedra Sinica) medicated serum group compared with the Wuweizi(Fructus Schisandrae Chinensis)medicated serum group. In contrast, CCR5, Kv1.3,and Kv1.5 proteins were expressed on the IM cell surface, and showed significantly higher expression in the Wuweizi(Fructus Schisandrae Chinensis)medicated serum group compared with the Mahuang(Herba Ephedra Sinica) medicated serum group.CONCLUSION: Mahuang(Herba Ephedra Sinica)and Wuweizi(Fructus Schisandrae Chinensis) can promote AM and IM migration ability, with Mahuang(Herba Ephedra Sinica) targeting AM more apparently and Wuweizi(Fructus Schisandrae Chinensis) targeting IM more apparently. The mechanism may be that, by stimulating cells, Mahuang(Herba Ephedra Sinica) and Wuweizi(Fructus Schisandrae Chinensis) promote expression of CCR2 and CCR5 receptors on the AM and IM cell surface,which pass signals to Kvl.3 and Kvl.5 ion channels,leading to changes in the cytoskeleton, and ultimately promoting chemotactic cell migration. | Yuan Yiping Zhai Huaqiang Zhang Tian Guo Zhaojuan Kong Liting Jia Xiaoyu Wang Ningning Dai Ying Liu Guoxiu Wang Yanping | 2017 | Journal of Traditional Chinese Medicine2017，37，5： | 3 |
| 13 | Flue Gas Water Recovery by Indirect Cooling Technology for Large-Scale Applications: A Review显示文摘With social development and economic enhancement,energy is facing significant worldwide demand,and fossil fuels are the prime energy sources for various energy systems over past decades.Furthermore,among fuel-consumed applications,power plants are the primary source of energy consumption.There is a lot of waste heat and steam accompanied by the latent heat produced in the exhaust flue gas.Therefore,the latent heat recovery from the flue gas plays an important role in increasing the efficiency of the system and saving water.To recover the heat and mass in power plants,three primary methods are proposed to condense the vapor based on previous studies:(1)flue gas condensation technology,(2)liquid desiccant-based dehydration(LDD)technology and(3)membrane technology.This paper mainly reviews and summaries the indirect cooling technology in flue gas condensation technology.The numerical simulation and theory of flue gas condensation are introduced.Different heat exchanger types and conducted experiments are also summarized.The performance of the indirect cooling technology is affected not only by its own configuration and design but also by the flue gas inlet temperature,velocity,water vapor mass fraction,etc.The major concerns and outlook of practical applications for further study are attributed to the heat exchanger size and cost,acid corrosion,ash accumulation in flue gas,etc. | ZHONG Wei JI Wenhui CAO Xiaoling YUAN Yanping | 2020 | Journal of Thermal Science2020，29，5： | 3 |
| 14 | Community-Based User Domain Model Collaborative Recommendation Algorithm显示文摘Collaborative Filtering (CF) is a commonly used technique in recommendation systems. It can promote items of interest to a target user from a large selection of available items. It is divided into two broad classes: memory-based algorithms and model-based algorithms. The latter requires some time to build a model but recommends online items quickly, while the former is time-consuming but does not require pre-building time. Considering the shortcomings of the two types of algorithms, we propose a novel Community-based User domain Collaborative Recommendation Algorithm (CUCRA). The idea comes from the fact that recommendations are usually made by users with similar preferences. The first step is to build a user-user social network based on users' preference data. The second step is to find communities with similar user preferences using a community detective algorithm. Finally, items are recommended to users by applying collaborative filtering on communities. Because we recommend items to users in communities instead of to an entire social network, the method has perfect online performance. Applying this method to a collaborative tagging system, experimental results show that the recommendation accuracy of CUCRA is relatively good, and the online time-complexity reduces to O.n/. | Fulan Qian Yanping Zhang Yuan Zhang Zhen Duan | 2013 | Tsinghua Science and Technology2013，18，4： | 3 |
| 15 | Structural basis of ALMT1-mediated aluminum resistance in Arabidopsis显示文摘The plant aluminum(Al)-activated malate transporter ALMT1 mediates the efflux of malate to chelate the Al in acidic soils and underlies the plant Al resistance.Here we present cryo-electron microscopy(cryo-EM)structures of Arabidopsis thaliana ALMT1(AtALMT1)in the apo,malate-bound,and Al-bound states at neutral and/or acidic pH at up to 3.0Åresolution.The AtALMT1 dimer assembles an anion channel and each subunit contains six transmembrane helices(TMs)and six cytosolicα-helices.Two pairs of Arg residues are located in the center of the channel pore and contribute to malate recognition.Al binds at the extracellular side of AtALMT1 and induces conformational changes of the TM1-2 loop and the TM5-6 loop,resulting in the opening of the extracellular gate.These structures,along with electrophysiological measurements,molecular dynamic simulations,and mutagenesis study in Arabidopsis,elucidate the structural basis for Al-activated malate transport by ALMT1. | Jiangqin Wang Xiafei Yu Zhong Jie Ding Xiaokang Zhang Yanping Luo Ximing Xu Yuan Xie Xiaoxiao Li Tian Yuan Shao Jian Zheng Wei Yang Jiangtao Guo | 2022 | Cell Research2022，32，1： | 3 |
| 16 | Optimisation of ultrasound-assisted extraction of phenolic compounds from wheat bran显示文摘 | Jing Wang Baoguo Sun Yanping Cao Yuan Tian Xuehong Li | 2007 | Food Chemistry2007，，2： | 3 |
| 17 | An Aerothermal Study of Influence of Blockage Ratio on a Supersonic Tube Train System显示文摘Evacuated tube transportation is an important development direction for the high-speed transportation technology of the future.However,a train running at supersonic speed in a closed tube can create an unstable aerothermal phenomenon,causing the temperature to rise sharply inside the tube and endangering the safe operation of trains and equipment.The blockage ratio is one of the key factors affecting the aerodynamic characteristics in the tube.In this paper,a 2 D axisymmetric model and Delayed Detached Eddy Simulation(DDES)based on the Shear Stress Transport(SST)k-ωturbulence model are used to study the aerothermal environment in the tube.The calculation method used in this paper was verified by a wind tunnel experiment.The aerothermal phenomenon and distribution of the flow field in the tube with different blockage ratios were compared and analysed.The results show that the aerothermal environment is significantly affected by the blockage ratio.A choking limit formed in the flow field will aggravate the aerodynamic phenomenon as the blockage ratio increases,which further deteriorates the aerothermal environment of the tube.Moreover,the existence of the choking limit,shock wave,and Mach disk make the flow field in the tube more complicated. | SUI Yang NIU Jiqiang YUAN Yanping YU Qiujun CAO Xiaoling WU Dan YANG Xiaofeng | 2022 | Journal of Thermal Science2022，31，2： | 2 |
| 18 | An approach to wide-field imaging of linear rail ground-based SAR in high squint multi-angle mode显示文摘Ground-based synthetic aperture radar(GB-SAR) has been successfully applied to the ground deformation monitoring.However, due to the short length of the GB-SAR platform, the scope of observation is largely limited. The practical applications drive us to make improvements on the conventional linear rail GB-SAR system in order to achieve larger field imaging. First, a turntable is utilized to support the rotational movement of the radar.Next, a series of high-squint scanning is performed with multiple squint angles. Further, the high squint modulation phase of the echo data is eliminated. Then, a new multi-angle imaging method is performed in the wave number domain to expand the field of view. Simulation and real experiments verify the effectiveness of this method. | ZHANG Yuan ZHANG Qiming WANG Yanping LIN Yun LI Yang BAI Zechao LI Fang | 2020 | Journal of Systems Engineering and Electronics2020，31，4： | 2 |
| 19 | Identification of two novel missense WFS1 mutations,H696Y and R703H,in patients with non-syndromic low-frequency sensorineural hearing loss显示文摘Non-syndromic 低频率的 sensorineural 听觉损失(LFSNHL ) 是听见在频率, 2000 Hz 主要被影响的损失的一种不平常的类型。迄今为止,在二基因, DIAPH1 和 WFS1 的不同变化,被发现了与 LFSNHL 被联系。这里,我们与 postlingual 和进步 LFSNHL 报导一个五产生的中国家庭。我们在在标记 SNP_A-2167174 和 D4S431 之间的染色体 4p16 上印射疾病地点到 2.5 Mb 区域,与 DFNA6/14/38 地点重叠。候选人基因定序揭示了异质接合的 c.2086C > 在 exon 的 T 替换 8 WFS1,在 Wolframin (WFS1 ) 的 C 终点导致 p.H696Y 替换。另外,我们执行了在 37 个分散的病人, WFS1 屏蔽的 mutational 750 岁,与 LFSNHL。我们检测了异质接合的 c.2108G > 在 exon 的替换 8 WFS1,在一个病人导致 p.R703H 替换。在 WFS1 的 H696 和 R703 高度越过种类被保存,包括人,猩猩,老鼠,老鼠,和青蛙(Xenopus ) 。顺序分析表明了 c.2086C 的缺席 > T 或 c.2108G > 在在中国背景的 200 个无关的控制题目之中的 WFS1 基因的 A 替换,支持他们代表的假设原因的变化,和不稀罕的多型性。我们的数据为为 LFSNHL 建立更好的 genotypephenotype 关联提供另外的分子、临床的信息。 | Yi Sun Jing Cheng Yanping Lu Jianzhong Li Yu Lu Zhanguo Jin Pu Dai Rongguang Wang Huijun Yuan | 2011 | Journal of Genetics and Genomics2011，38，2： | 2 |
| 20 | Daylight and thermal performance of a switchable ethylene tetra-fluoro-ethylene cushion with dynamic control in different climates显示文摘Switchable multi-layer ethylene tetra-fluoro-ethylene(ETFE)cushion controls the natural light and heat flux passing through the cushion with varying outdoor conditions by dynamically modifying its properties.In this paper,the switchable ETFE cushions with ink printing of different optical and thermal properties were adopted as the window in a typical office model,and the indoor daylight and energy consumption were simulated by using Grasshopper software.Experimental model was built to validate the numerical model.Five locations representing five climate zones in China were selected to analyze the feasibility of the switchable ETFE cushion in different climates.The hourly indoor daylight and heat gain in a single day revealed the effects of the dynamic mechanism of ETFE cushion in improving indoor natural light and thermal environment.In addition,the annual daylight performance at the working area(1.5 m from the window)was simulated.ETFE cushion with printing of the lowest transmittance(ETFE1)was the optimal option for most cities and window-to-wall ratios,with the percentage of annual useful daylight hours up to 78.6%,except for the cases where the window-to-wall ratio(WWR)was 0.35 in Harbin,Beijing,and Hefei.The distribution of useful daylight hours revealed that ETFE cushions with low,medium,and high printing transmittance were suitable for offices where people work in the front,medium,and back region of the room,respectively.Energy consumption calculation revealed that ETFE1 showed advantages over other windows in most cities except for cities highly dominated by heating.ETFE1 delivered up to 33%of energy saving over a year in Kunming compared with the conventional double glazing but was not superior in cities with high heating and low cooling demands,such as Harbin. | Wanfang Zhao Wei He Zhongting Hu Xiaoyu Zheng Sheng Zhang Gaofei Xu Hongbing Chen Yanping Yuan | 2022 | Building Simulation2022，15，1： | 2 |
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