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| 1 | The δ^(18)O variation of a stalagmite from Qixing Cave,Guizhou Province and indi-cated climate change during the Holocene显示文摘A stalagmite from Qixing Cave, Guizhou Province was dated with the TIMS U-series method and its oxygen isotope composition was analyzed. On the basis of the ages and the variations of the δ18O of the stalagmite, the climate change of the last 7.7 ka has been reconstructed in this area: 7.7-5.8 ka, summer monsoon maximum period; 5.8-3.8 ka summer monsoon weakening period; 3.8-0.15 ka, weakened summer monsoon and high amplitude climate fluctuations period. We put forward that the increasing trend of δ18O of the stalagmite reflected not only the weakening of the summer monsoon, which was caused by the decreasing of solar radiation in the Northern Hemisphere, but also the possibly decreasing contribution of the southwest monsoon to the rainfall of this area. These results are consistent with the output of the numerical climate-model modeling. The high amplitude fluctuation of the δ18O may imply the quick shift of the contributions of different moisture sources to the precipitation in this area. | CAI Yanjun, ZHANG Meiliang, PENG Zicheng, LIN Yushi, AN Zhisheng, ZHANG Zhaofeng & CAO YunningState Key Laboratory of Loess and Quaternary Geology, Institute of Earth Environment, Chinese Academy of Sciences, Xi’an 710054, China Karst Dynamics Laboratory, Ministry of Land and Resources, Guilin 541003, China Department of Earth and Space Science, University of Science & Technology of China, Hefei 230023, China | 2001 | Chinese Science Bulletin2001，46，22： | 18 |
| 2 | Approximate Solution of Oil Film Load-carrying Capacity of Turbulent Journal Bearing with Couple Stress Flow显示文摘The instability of the rotor dynamic system supported by oil journal bearing is encountered frequently, such as the half-speed whirl of the rotor, which is caused by oil film lubricant with nonlinearity. Currently, more attention is paid to the physical characteristics of oil film due to an oil-lubricated journal bearing being the important supporting component of the bearing-rotor systems and its nonlinear nature. In order to analyze the lubrication characteristics of journal bearings efficiently and save computational efforts, an approximate solution of nonlinear oil film forces of a finite length turbulent journal bearing with couple stress flow is proposed based on Sommerfeld and Ocvirk numbers. Reynolds equation in lubrication of a finite length turbulent journal bearing is solved based on multi-parametric principle. Load-carrying capacity of nonlinear oil film is obtained, and the results obtained by different methods are compared. The validation of the proposed method is verified, meanwhile, the relationships of load-carrying capacity versus eccentricity ratio and width-to-diameter ratio under turbulent and couple stress working conditions are analyzed. The numerical results show that both couple stress flow and eccentricity ratio have obvious influence on oil film pressure distribution, and the proposed method approximates the load-carrying capacity of turbulent journal bearings efficiently with various width-to-diameter ratios. This research proposes an approximate solution of oil film load-carrying capacity of turbulent journal bearings with different width-to-diameter ratios, which are suitable for high eccentricity ratios and heavy loads. | ZHANG Yongfang WU Peng GUO Bo L Yanjun LIU Fuxi YU Yingtian | 2015 | Chinese Journal of Mechanical Engineering2015，28，1： | 10 |
| 3 | Performance enhancement of perovskite-sensitized mesoscopic solar cells using Nb-doped TiO2 compact layer显示文摘Perovskite 太阳能电池是常规光电的设备的最有希望的选择之一,并且广泛的研究集中于设备优化进一步改进他们的表演。TiO 2 的紧缩的层通常在 perovskite 太阳能电池被使用阻止到达做氟的符号的听氧化物电极接近洞。在这贡献,我们用做的 Nb 设计了 TiO 2 协议层,它与 10.26% 的力量变换效率(PCE ) 导致了太阳能电池,它比有一样的配置的设备的高,但是包含太古的 TiO 2 协议层(PCE =9.22%) 。设备表演改进被归因于减少的选择接触抵抗并且增加了源于做的 Nb 的费用再结合抵抗,它被阻抗光谱学大小揭示。发达策略为 perovskite 太阳能电池强调接口优化的重要性。 | Xiong Yin Yanjun Guo Zhaosheng Xue Peng Xu Meng He Bin Liu | 2015 | Nano Research2015，8，6： | 9 |
| 4 | Mechanism for suspension magnetization roasting of iron ore using straw-type biomass reductant显示文摘As an alternative reductant for fossil fuel in the future,straw-type biomass contributes to emission reduction and green utilization in the suspension roasting process.In this study,the influences of the roasting time,roasting temperature and dose of straw-type biomass after suspension magnetization roasting(SMR) and separation were investigated.The optimal conditions were determined to be a roasting time of 7.5 min with a straw-type biomass dose of 20 wt% and a roasting temperature of 800℃ in which an iron grade of 71.07% and recovery of 94.17% were obtained for the iron concentrate.The maximum saturation magnetization under optimal conditions was 35.05 A·m^(2)·g^(-1),and the gaseous regulation of the biomass revealed that cumulative reducing gas volume was 293.93 mL at the optimal roasting time of450 s.The transformation of hematite to magnetite was detected by X-ray diffraction(XRD).During microstructure evolution,the outer layer consisting of fissures and tiny holes continuously deepened toward the core. | Yue Cao Yongsheng Sun Peng Gao Yuexin Han Yanjun Li | 2021 | International Journal of Mining Science and Technology2021，31，6： | 8 |
| 5 | Characterization and mapping of a novel mutant sms1 (senescence and male sterility 1) in rice显示文摘Plant senescence plays diverse important roles in development and environmental responses.However,the molecular basis of plant senescence is remained largely unknown.A rice spontaneous mutant with the character of early senescence and male sterility (sms) was found in the breeding line NT10-748.In order to identify the gene SMS1 and the underlying mechanism,we preliminarily analyzed physiological and biochemical phenotypes of the mutant.The mutant contained lower chlorophyll content compared with the wild type control and was severe male sterile with lower pollen viability.Genetic analysis showed that the mutant was controlled by a single recessive gene.By the map-based cloning approach,we fine-mapped SMS1 to a 67 kb region between the markers Z3-4 and Z1-1 on chromosome 8 using 1,074 F2 recessive plants derived from the cross between the mutant sms1 (japonica) × Zhenshan 97 (indica),where no known gene involved in senescence or male sterility has been identified.Therefore the SMS1 gene will be a novel gene that regulates the two developmental processes.The further cloning and functional analysis of the SMS1 gene is under way. | Wenyi Yan Shenghai Ye Qingsheng Jin Longjun Zeng Yu Peng Dawei Yan Weibing Yang Donglei Yang Zuhua He Yanjun Dong Xiaoming Zhang | 2010 | Journal of Genetics and Genomics2010，37，1： | 6 |
| 6 | Orbital-scale Asian summer monsoon variations:Paradox and exploration显示文摘The Asian summer monsoon(ASM) is a vast climate system, whose variability is critical to the livelihoods of billions of people across the Asian continent. During the past half-century, much progress has been made in understanding variations on a wide range of timescales, yet several significant issues remain unresolved. Of note are two long-standing problems concerning orbital-scale variations of the ASM.(1) Chinese loess magnetic susceptibility records show a persistent glacial-interglacial dominated ~100 kyr(thousand years) periodicity, while the cave oxygen-isotope(δ18 O) records reveal periodicity in an almost pure precession band(~20 kyr periodicity)—the 'Chinese 100 kyr problem'.(2) ASM records from the Arabian Sea and other oceans surrounding the Asian continent show a significant lag of 8–10 kyr to Northern Hemisphere summer insolation(NHSI), whereas the Asian cave δ18 O records follow NHSI without a significant lag—a discrepancy termed the 'sea-land precession-phase paradox'. How can we reconcile these differences? Recent and more refined model simulations now provide spatial patterns of rainfall and wind across the precession cycle, revealing distinct regional divergences in the ASM domain, which can well explain a large portion of the disparities between the loess, marine, and cave proxy records. Overall, we also find that the loess, marine, and cave records are indeed complementary rather than incompatible, with each record preferentially describing a certain aspect of ASM dynamics. Our study provides new insight into the understanding of different hydroclimatic proxies and largely reconciles the 'Chinese 100 kyr problem' and 'sea-land precession-phase paradox'. | Hai CHENG Haiwei ZHANG Yanjun CAI Zhengguo SHI Liang YI Chenglong DENG Qingzhen HAO Youbing PENG Ashish SINHA Hanying LI Jingyao ZHAO Ye TIAN Jonathan BAKER Carlos PEREZ-MEJIAS | 2021 | Science China Earth Sciences2021，64，4： | 6 |
| 7 | Phenformin alone or combined with gefitinib inhibits bladder cancer via AMPK and EGFR pathways显示文摘Background:In previous studies,we have shown that the combination of metformin and gefitinib inhibits the growth of bladder cancer cells.Here we examined whether the metformin analogue phenformin,either used alone or in combination with gefitinib,could inhibit growth of bladder cancer cells.Methods:The growth-inhibitory effects of phenformin and gefitinib were tested in one murine and two human bladder cancer cell lines using MTT and clonogenic assays.Effects on cell migration were assessed in a wound healing assay.Synergistic action between the two drugs was assessed using CompuSyn software.The potential involvement of AMPK and EGFR pathways in the effects of phenformin and gefitinib was explored using Western blotting.Results:In MTT and clonogenic assays,phenformin was>10-fold more potent than metformin in inhibiting bladder cancer cell growth.Phenformin also potently inhibited cell migration in wound healing assays,and promoted apop-tosis.AMPK signaling was activated;EGFR signaling was inhibited.Phenformin was synergistic with gefitinib,with the combination of drugs showing much stronger anticancer activity and apoptotic activation than phenformin alone.Conclusions:Phenformin shows potential as an effective drug against bladder cancer,either alone or in combination with gefitinib. | Yanjun Huang Sichun Zhou Caimei He Jun Deng Ting Tao Qiongli Su Kwame Oteng Darko Mei Peng Xiaoping Yang | 2018 | Cancer Communications2018，38，1： | 5 |
| 8 | Non-obstructive Coronary Artery Disease in Chinese Patients with Angina Diagnosed by Coronary Angiography:A Retrospective Study显示文摘Objective:This study aimed to estimate the proportion of non-obstructive coronary artery disease(CAD)patients in large percutaneous coronary intervention(PCI)centers in China.Methods:The study was conducted at 6 large PCI centers in China from January 1,2013 to December 31,2015.Demographic and clinical data were collected from medical records,prescription records,and laboratory reports of patients with symptoms of angina who underwent coronary angiography(CAG).Results:A total of 1713 patients were consecutively screened,1600 of whom were included in the study.CAG showed that 300 patients had non-obstructive CAD while 1300 had obstructive CAD.Among the 300 patients with non-obstructive CAD,203 displayed mild coronary stenosis(20%-49%)and 91 had normal coronary status(ie,<20%stenosis).Of the 1300 patients with obstructive CAD,61.6%(801/1300)had typical symptoms of angina,compared with 49.3%(148/300)for patients with nonobstructive CAD.In addition,there were more women than men in the non-obstructive CAD group,whereas the reverse was observed among obstructive CAD patients.Conclusion:The prevalence of non-obstructive CAD in the Chinese population with coronary heart disease was estimated to be approximately 20%.Additionally,typical angina symptoms were correlated with obstructive CAD,whereas female gender was identified as a risk factor for non-obstructive CAD. | Chengfei Peng Shaoping Nie Yingxian Sun Hui Chen Zuyi Yuan Yanjun Gong Xiaozeng Wang Yaling Han | 2021 | Cardiology Discovery2021，1，4： | 4 |
| 9 | Searching for the Nano-Hertz Stochastic Gravitational Wave Background with the Chinese Pulsar Timing Array Data ReleaseⅠ显示文摘Observing and timing a group of millisecond pulsars with high rotational stability enables the direct detection of gravitational waves(GWs).The GW signals can be identified from the spatial correlations encoded in the times-of-arrival of widely spaced pulsar-pairs.The Chinese Pulsar Timing Array(CPTA)is a collaboration aiming at the direct GW detection with observations carried out using Chinese radio telescopes.This short article serves as a“table of contents”for a forthcoming series of papers related to the CPTA Data Release 1(CPTA DR1)which uses observations from the Five-hundred-meter Aperture Spherical radio Telescope.Here,after summarizing the time span and accuracy of CPTA DR1,we report the key results of our statistical inference finding a correlated signal with amplitude logA_(c)=-14.4_(-2.8)^(+1.0)for spectral index in the range ofα∈[-1.8,1.5]assuming a GW background(GWB)induced quadrupolar correlation.The search for the Hellings–Downs(HD)correlation curve is also presented,where some evidence for the HD correlation has been found that a 4.6σstatistical significance is achieved using the discrete frequency method around the frequency of 14 n Hz.We expect that the future International Pulsar Timing Array data analysis and the next CPTA data release will be more sensitive to the n Hz GWB,which could verify the current results. | Heng Xu Siyuan Chen Yanjun Guo Jinchen Jiang Bojun Wang Jiangwei Xu Zihan Xue RNicolas Caballero Jianping Yuan Yonghua Xu Jingbo Wang Longfei Hao Jingtao Luo Kejia Lee Jinlin Han Peng Jiang Zhiqiang Shen Min Wang Na Wang Renxin Xu Xiangping Wu Richard Manchester Lei Qian Xin Guan Menglin Huang Chun Sun Yan Zhu | 2023 | Research in Astronomy and Astrophysics2023，23，7： | 3 |
| 10 | Orthogonal resource sharing scheme for device-to-device communication overlaying cellular networks: a cooperative relay based approach显示文摘In this paper, we propose a device-to-device(D2D) communication scheme to improve local services in cellular networks. By employing cooperative relay(CR) technology, D2 D and cellular communications can operate in orthogonal resource sharing(ORS) mode with the aim of optimizing the data rates for local D2 D users while fulfilling the minimum rate requirements for prioritized cellular users. In the proposed CR-based ORS scheme, we consider a cellular communication that is willing to share part of the occupied bandwidth resource with some D2 D communications. Hence, the newly-obtained resource can be used by a D2 D communication for the following two purposes, i.e., to compensate the rate loss of the cellular communication through cooperative relaying and to communicate its own information so as to increase its own rate. We formulated this CR-based ORS problem as a non-convex optimization problem. Hence, a global maximizer may not exist for the problem.To find the optimal solution for the problem, an effective heuristic algorithm is developed. Simulation results show that the proposed D2 D communication scheme can significantly increase the rates of local D2 D users and also fulfill the minimum rate requirements of cellular users. | ZHANG GuoPeng LIU Peng YANG Kun DU Yao HU YanJun | 2015 | Science China(Information Sciences)2015，58，10： | 3 |
| 11 | Improving the Weld Formation and Mechanical Properties of the AA-5A06 Friction Pull Plug Welds by Axial Force Control显示文摘In the present study, the weld formation and mechanical properties of the AA-5A06 friction pull plug welded(FPPW) joints were improved by controlling the axial force history. Several defect-free FPPW joints were made successfully by using the welding parameters of 15–20 k N/s axial loading rate, 20–30 k N axial welding force and 6–7 mm axial feeding displacement. The results indicated that using higher axial loading rate and axial welding force produced more stable heat generation and shorter frictional heating time between the frictional interface. In this case, the plastic flow of the materials around the hole could be further improved since the axial feeding displacement of the plug was increased. The maximum ultimate tensile strength(UTS) and elongation of the FPPW 5A06 joints were 314 MPa and 4.8%, respectively. The thermal mechanically affect zone(TMAZ) had the lowest hardness value throughout the joint and was found as the fracture location to all the tensile samples. The softening of TMAZ was mainly caused by the weakening of the cold work hardening and the coarsening of grains. | Jinyong Gao Lijun Yang Lei Cui Peng Lu Jun Yang Yanjun Gao | 2020 | Acta Metallurgica Sinica(English Letters)2020，33，6： | 3 |
| 12 | Preparation and Characterization of Co_(3)O_(4)/Graphene/Cellulose Nanofiber Composite Films显示文摘Nanocellulose has served as an eye-catching nanomaterial for constructing advanced functional devices with renewability,light weight,flexibility,and environmental friendliness.In this study,Co_(3)O_(4)/graphene/cellulose nanofiber(CNF)flexible composite films,in which the CNF acted as a spacer for the graphene,were prepared via a facile and scalable vacuum filtration method.The effects of the CNF on the microstructure,hydrophilicity,thermal stability,tensile strength,surface resistance,and electrochemical performance of the Co_(3)O_(4)/graphene/CNF composite films were systematically investigated.The results showed that the synergistic interaction of the CNF and graphene substantially improved the overall properties of the Co_(3)O_(4)/graphene/CNF composite films,particularly their hydrophilicity and tensile strength.Meanwhile,Co_(3)O_(4)/graphene/CNF composite films with a CNF content of 4%appeared to have the optimal electrochemical performance,with an area specific capacitance of 56 mF/cm^(2) and prominent capacitance retention of 95.6%at a current density of 1 A/g after 1000 cycles.This work demonstrated that the prepared Co_(3)O_(4)/graphene/CNF flexible composite films have great application potential in the field of flexible energy storage devices. | Zejun Ding Tianying Chen Yiming Zhou Peng Zhu Feiyun Li Yanjun Tang | 2022 | Paper And Biomaterials2022，7，2： | 2 |
| 13 | A glutathione activatable pro-drug-photosensitizer for combined chemotherapy and photodynamic therapy显示文摘During cancer treatment,chemotherapeutic drugs always result in severe side-effects and drug resistance.Therefore,combining cheomtherapy with other therapeutic modalities,such as photodynamic therapy(PDT)and designing an activable platform is promising for precise and efficient anticancer treatment.Herein,we report a“pro-drug-photosensitizer”agent,LMB-S-CPT,bearing a disulfide bond as the glutathione(GSH)-activatable linker.LMB-S-CPT can be selectively activated by GSH to release activated drug,camptothecin(CPT),for chemotherapy and activated photosensitizer,methylene blue(MB),for PDT.LMB-S-CPT exhibits excellent tumor-activatable performance when injected into tumor-bearing mice,as well as specific cancer therapy with negligible toxic side effects.The activatable pro-drug-photosensitizer offers a new strategy for chemo-photodynamic therapy and displays precise,selective and excellent antitumor effect. | Yanjun Yang Yifeng Zhang Ran Wang Xiang Rong Ting Liu Xiang Xia Jiangli Fan Wen Sun Xiaojun Peng | 2022 | Chinese Chemical Letters2022，33，10： | 2 |
| 14 | PM_(2.5) exposure associated with microbiota gut-brain axis:Multi-omics mechanistic implications from the BAPE study显示文摘Recent studies have shown that PM_(2.5) may activate the hypothalamus-pituitary-adrenal(HPA)axis by inducing hormonal changes,potentially explaining the increase in neurological and cardiovascular risks.In addition,an association between PM_(2.5) and gut microbiota and metabolites was established.The above evidence represents crucial parts of the gut-brain axis(GBA).In view of this evidence. | Tiantian Li Jianlong Fang Song Tang Hang Du Liang Zhao Yanwen Wang Fuchang Deng Yuanyuan Liu Yanjun Du Liangliang Cui Wanying Shi Yan Wang Jiaonan Wang Yingjian Zhang Xiaoyan Dong Ying Gao Yu Shen Li Dong Huichan Zhou Qinghua Sun Haoran Dong Xiumiao Peng Yi Zhang Meng Cao Hong Zhi Jingyang Zhou Xiaoming Shi | 2022 | The Innovation2022，3，2： | 2 |
| 15 | Structure-based development of three- and four-antibody cocktails against SARS-CoV-2 via multiple mechanisms显示文摘The ongoing coronavirus disease 2019(COVID-19)pandemic caused by severe acute respiratory syndrome coronavirus-2(SARS-CoV-2)has resulted in an unprecedented public health crisis,galvanizing a global effort for rapidly developing new therapeutic strategies effective against COVID-19.Human monoclonal antibodies(mAbs)are promising therapeutic molecules that can be used for the prevention or treatment of viral infectious diseases,including COVID-19.For instance,ZMapp^(TM),a cocktail consisting of three different mAbs targeting the Ebola glycoprotein is one of the most successful antibody-based therapeutic for treating infections caused by Ebola virus.1 Notably,this cocktail combines the best-performing neutralizing antibodies(NAbs)screened and developed using two separate approaches,one from humanized antibodies of origin and the other from human survivors. | Yao Sun Lei Wang Rui Feng Nan Wang Yuxi Wang Dandan Zhu Xiaorui Xing Peng Yang Yanjun Zhang Weimin Li Xiangxi Wang | 2021 | Cell Research2021，31，5： | 2 |
| 16 | Finite time dual neural networks with a tunable activation function for solving quadratic programming problems and its application显示文摘 | Miao Peng Shen Yanjun Xia Xiaohua | 2014 | Neurocomputing2014，143，： | 1 |
| 17 | ADAM10 overexpression in human non-small cell lung cancer correlateswith cell migration and invasion through the activation of the Notch1 signalingpathway显示文摘 | Jianli Guo Lei He Ping Yuan Peng Wang Yanjun Lu Fangli Tong Yu Wang Yanhua Yin Jun Tian Jun Sun | 2012 | Oncology Reports2012，，： | 1 |
| 18 | Solving time-varying quadratic programs based on finite-time Zhang neural networks and their application to robot tracking显示文摘 | Miao Peng Shen Yanjun Huang Yuehua | 2015 | Neural Computing and Application2015，26，3： | 1 |
| 19 | Finite-time stability and its application for solving time-varying Sylvester equation by recurrent neural network显示文摘 | Shen Yanjun Miao Peng Huang Yuehua | 2015 | Neural Process Lett2015，42，3： | 1 |
| 20 | Review on coal-based reduction and magnetic separation for refractory iron-bearing resources显示文摘The application of coal-based reduction in the efficient recovery of iron from refractory iron-bearing resources is comprehensively reviewed.Currently,the development and beneficiation of refractory iron-bearing resources have attracted increasing attention.However,the effect of iron recovery by traditional beneficiation methods is unacceptable.Coal-based reduction followed by magnetic separation is proposed,which adopts coal as the reductant to reduce iron oxides to metallic iron below the melting temperature.The metallic iron particles aggregate and grow,and the particle size continuously increases to be suitable for magnetic separation.The optimization and application of coal-based reduction have been abundantly researched.A detailed literature study on coal-based reduction is performed from the perspectives of thermodynamics,reduction kinetics,growth of metallic iron particles,additives,and application.The coal-based reduction industrial equipment can be developed based on the existing pyrometallurgical equipments,rotary hearth furnace and rotary kiln,which are introduced briefly.However,coal-based reduction currently mainly adopts coal as a reductant and fuel,which may result in high levels of carbon dioxide emissions,energy consumption,and pollution.Technological innovation aiming at decreasing carbon dioxide emissions is a new trend of green and sustainable development of the steel industry.Therefore,the substitution of coal with clean energy(hydrogen,biomass,etc.)for iron oxide reduction shows promise in the future. | Qiang Zhang Yongsheng Sun Yuexin Han Yanjun Li Peng Gao | 2022 | International Journal of Minerals,Metallurgy and Materials2022，29，12： | 1 |
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