|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Overexpression of the Wounding-Responsive Gene AtMYB15 Activates the Shikimate Pathway in Arabidopsis显示文摘MYB 抄写因素基因在许多发展过程和植物的各种各样的防卫回答起重要作用。shikimate 小径是为三芳香的氨基酸和涉及植物的多重回答的另外的芳香的混合物的生产的一条主要 biosynthetic 小径,包括保护对紫外并且防卫。此处,我们在 Arabidopsis 把 R2R3-MYB 基因 AtMYB15 的描述描述为 shikimate 小径的使活跃之物。AtMYB15 蛋白质是原子的局部性并且一个 transcriptional 激活领域在它的 C 终端部分被发现。北污点证明 AtMYB15 是早创伤可诱导的基因。microarray 分析的 Resutls,使用量的即时聚合酶链反应证实,证明在转基因的植物的 AtMYB15 的 overexpression 导致了涉及 shikimate 小径的几乎所有基因的提高的表示。生物信息学分析证明至少一个 AtMYB15 有约束力的交流元素在这些 upregulated 基因的倡导者被检测。而且,在 shikimate 小径的这些基因也被发现被伤害导致。这些数据响应伤害作为 Arabidopsis shikimate 小径的一个可能的直接管理者建议 AtMYB15 的一个重要角色。 | Yanhui Chen Xiangbo Zhang Wei Wu Zhangliang Chen Hongya Gu Li-Jia Qu | 2006 | Journal of Integrative Plant Biology2006，48，9： | 7 |
| 2 | 肠系膜上静脉血管鞘内入路在右半结肠切除术中的临床研究(英文)显示文摘Objective: The aim of the study was to investigate the clinical value of superior mesenteric vascular intrathecal approach in right hemicolectomy. Methods: We retrospectively studied the clinical data of 132 patients who had right hemicolectomy from June 2007 to June 2010, including 68 cases with superior mesenteric vascular intrathecal approach to resect specimen, and compared the operation time, blood loss, hospital stay and the number of dissected lymph nodes with patients treated with conventional surgery. Results: Compared the vascular intrathecal approach with conventional approach, the operation time and blood loss were decreased significantly, the number of Dukes C No. 3 lymph node dissection was increased, while the incidence of postoperative complications and hospital stay were equivalent to traditional surgery group. Conclusion: The use of vascular intrathecal approach in right hemicolectomy can significantly shorten the operation time and reduce bleeding and improve surgical radical outcomes. | Yuzhou Zhao, Guangsen Han, Yingkun Ren, Yanhui Gu, Chaomin Lu Department of General Surgery, Henan Tumor Hospital Affiliated Tumor Hospital, Zhengzhou University, Zhengzhou 450003, China | 2010 | The Chinese-German Journal of Clinical Oncology2010，9，11： | 6 |
| 3 | Cloning and analysis of a cDNA encoding acetohydroxy acid isomeroreductase from G2 pea显示文摘Using cDNA representational difference analysis (cDNA RDA) method, we have successfully isolated a gene fragment whose expression was specifically induced by external GAa application. Screening a G2 pea cDNA library using this fragment as a probe, we obtained a 2036 bp full-length cDNA. It contains a 1746 bp open reading frame and encodes a protein of 581 amino acids with a theoretical molecular weight of 64 ku. It shares high-level sequenceidentity with AAIR genes from other plant species. This cDNA was cloned into expression vector and recombinant E. coli DH5α cells with remarkable AAIR enzyme activity were obtained. | XU Huasong XU Yunjian GU Xuesong HU Tingzhang SU Yanhui ZHU Yuxian | 2001 | Chinese Science Bulletin2001，46，21： | 4 |
| 4 | Effect of Preparation Method on the Structural Characteristics of NiO-ZrO2 Oxygen Carriers for Chemical-looping Combustion显示文摘Chemical-looping combustion(CLC)offers an effective approach for power generation and CO2 capture.In this work,an NiO-ZrO2 oxygen carrier prepared by three methods was subjected to an optimal reaction temperature test,an optimal flow test and a cyclic redox reaction test to explore the most suitable reaction conditions.Through comparative analysis,it is noted that the coprecipitation method is not suitable for the preparation of this NiO-ZrO2 oxygen carrier,while the oxygen carrier prepared by the mechanical mixing method and solution combustion method obtained a higher CH4 conversion rate and CO2 selectivity.In addition,these two oxygen carriers also showed high stability during successive CLC testing.Therefore,both the mechanical mixing method and the solution combustion method can be used to prepare NiO-ZrO2 oxygen carriers. | LIU Yike LONG Yanhui TANG Yaqin GU Zhenhua LI Kongzhai | 2019 | Chemical Research in Chinese Universities2019，35，6： | 2 |
| 5 | Hydrogen production via chemical looping reforming of coke oven gas显示文摘Coke oven gas(COG)is one of the most important by-products in steel industry,and the conversion of COG to value-added products has attracted much attention from both economic and environmental views.In this work,we use the chemical looping reforming technology to produce pure H_(2) from COG.A series of La1-xSrxFeO_(3)(x?0,0.2,0.3,0.4,0.5,0.6)perovskite oxides were prepared as oxygen carriers for this purpose.The reduction behaviors of La1-xSrxFeO_(3) perovskite by different reducing gases(H_(2),CO,CH4 and the mixed gases)are investigated to discuss the competition effect of different components in COG for reacting with the oxygen carriers.The results show that reduction temperatures of H_(2) and CO are much lower than that of CH4,and high temperatures(>800℃)are requested for selective oxidation of methane to syngas.The co-existence of CO and H_(2) shows weak effect on the equilibrium of methane conversion at high temperatures,but the oxidation of methane to syngas can inhibit the consumption of CO and H_(2).The doping of suitable amounts of Sr in LaFeO_(3) perovskite(e.g.,La0.5Sr0.5FeO_(3))significantly promotes the activity for selective oxidation of methane to syngas and inhibits the formation of carbon deposition,obtaining both high methane conversion in the COG oxidation step and high hydrogen yield in the water splitting step.The La0.5Sr0.5FeO_(3) shows the highest methane conversion(67.82%),hydrogen yield(3.34 mmol g^(-1))and hydrogen purity(99.85%).The hydrogen yield in water splitting step is treble as high as the hydrogen consumption in reduction step.These results reveal that chemical looping reforming of COG to produce pure H_(2) is feasible,and an O_(2)-assistant chemical looping reforming process can further improves the redox stability of oxygen carrier. | Kun Yang Zhenhua Gu Yanhui Long Shen Lin Chunqiang Lu Xing Zhu Hua Wang Kongzhai Li | 2021 | Green Energy & Environment2021，6，5： | 2 |
| 6 | The cancer-testis gene,MEIOB,sensitizes triple-negative breast cancer to PARP1 inhibitors by inducing homologous recombination deficiency显示文摘Objective:The newly defined cancer-testis(CT)gene,MEIOB,was previously found to play key roles in DNA double-strand break(DSB)repair.In this study,we aimed to investigate the effects and mechanisms of MEIOB in the carcinogenesis of triple-negative breast cancers(TNBCs).Methods:The Cancer Genome Atlas database was used to quantify the expression of MEIOB.Cox regression analysis was used to evaluate the association between MEIOB expression and the prognosis of human TNBC.The effects of MEIOB on cell proliferation and migration in TNBCs were also assessed in vitro.Patient-derived xenograft(PDX)models were used to assess the sensitivity of breast cancers with active MEIOB to PARP1 inhibitors.Results:We confirmed MEIOB as a CT gene whose expression was restricted to the testes and breast tumors,especially TNBCs.Its activation was significantly associated with poor survival in breast cancer patients[overall,hazard ratio(HR)=1.90(1.16–2.06);TNBCs:HR=7.05(1.16–41.80)].In addition,we found that MEIOB was oncogenic and significantly promoted the proliferation of TNBC cells.Further analysis showed that MEIOB participated in DSB repair in TNBCs.However,in contrast to its function in meiosis,it mediated homologous recombination deficiency(HRD)through the activation of poly ADP-ribose polymerase(PARP)1 by interacting with YBX1.Furthermore,activated MEIOB was shown to confer sensitivity to PARP inhibitors,which was confirmed in PDX models.Conclusions:MEIOB played an oncogenic role in TNBC through its involvement in HRD.In addition,dysregulation of MEIOB sensitized TNBC cells to PARP inhibitors,so MEIOB may be a therapeutic target of PARP1 inhibitors in TNBC. | Yayun Gu Cheng Wang Rongxuan Zhu Jianshui Yang Wenwen Yuan Yanhui Zhu Yan Zhou Na Qin Hongbing Shen Hongxia Ma Hongxia Wang Xiaoan Liu Zhibin Hu | 2021 | Cancer Biology & Medicine2021，18，1： | 2 |
| 7 | Surface and optical properties of silicon nitride deposited by inductively coupled plasma-chemical vapor deposition显示文摘The surface and optical properties of silicon nitride samples with different compositions were investigated. The samples were deposited on In P by inductively coupled plasma chemical vapor deposition using different NH_3 flow rates. Atomic force microscopy measurements show that the surface roughness is increased for the samples with both low and high NH_3 flow rates. By optimization, when the NH_3 flow rate is 6 sccm, a smooth surface with RMS roughness of 0.74 nm over a 5 × 5 μm^2 area has been achieved. X-ray photoelectron spectroscopy measurements reveal the Si/N ratio of the samples as a function of NH_3 flow rate. It is found that amorphous silicon is dominant in the samples with low NH_3 flow rates, which is also proved in Raman measurements. The bonding energies of the Si and N atoms have been extracted and analyzed. Results show that the bonding states of Si atoms transfer from Si^0 to Si^(+4) as the NH_3 flow rate increases. | Yi Zhu Xingyou Chen Yingjie Ma Yonggang Zhang Ben Du Yanhui Shi Yi Gu | 2018 | Journal of Semiconductors2018，39，8： | 1 |
| 8 | Hydrazine bisborane as a promising material for chemical hydrogen storage 显示文摘 | SUN Weiwei GU Qinfen GUO Yanhui | 2011 | Fuel & Energy Abstracts2011，36，13： | 1 |
| 9 | Structure and decomposition of zinc borohydride ammonia adduet: towardsa pure hydrogen release 显示文摘 | Gu Qinfen Gao Liang Guo Yanhui | 2012 | Energy ~ Envi- ronmental Science2012，5，6： | 1 |
| 10 | Improving Chinese Word Representation with Conceptual Semantics显示文摘The meaning of a word includes a conceptual meaning and a distributive meaning.Word embedding based on distribution suffers from insufficient conceptual semantic representation caused by data sparsity,especially for low-frequency words.In knowledge bases,manually annotated semantic knowledge is stable and the essential attributes of words are accurately denoted.In this paper,we propose a Conceptual Semantics Enhanced Word Representation(CEWR)model,computing the synset embedding and hypernym embedding of Chinese words based on the Tongyici Cilin thesaurus,and aggregating it with distributed word representation to have both distributed information and the conceptual meaning encoded in the representation of words.We evaluate the CEWR model on two tasks:word similarity computation and short text classification.The Spearman correlation between model results and human judgement are improved to 64.71%,81.84%,and 85.16%on Wordsim297,MC30,and RG65,respectively.Moreover,CEWR improves the F1 score by 3%in the short text classification task.The experimental results show that CEWR can represent words in a more informative approach than distributed word embedding.This proves that conceptual semantics,especially hypernymous information,is a good complement to distributed word representation. | Tingxin Wei Weiguang Qu Junsheng Zhou Yunfei Long Yanhui Gu Zhentao Xia | 2020 | Computers, Materials & Continua2020，，9： | 1 |
| 11 | The MYB Transcription Factor Superfamily of Arabidopsis: Expression Analysis and Phylogenetic Comparison with the Rice MYB Family显示文摘 | Chen Yanhui Yang Xiaoyuan He Kun Liu Meihua Li Jigang Gao Zhaofeng Lin Zhiqiang Zhang Yunfei Wang Xiaoxiao Qiu Xiaoming Shen Yunping Zhang Li Deng Xiaohui Luo Jingchu Deng Xing-Wang Chen Zhangliang Gu Hongya Qu Li-Jia | 2006 | Plant Molecular Biology2006，，1： | 1 |
| 12 | Fast-chargingand dendrite-free lithiummetal anodeeenabledby partial lithiation ofgraphene aerogel显示文摘The development of deeply cyclable lithium metal batteries with fast-charging capability offers a promising solution to relieve the“range anxiety”in driving electric vehicles.Conventional lithium metal anodes suffered from low operating current densities and shallow charge/discharge depths,owing to the intrinsic dendrite growth governed by Sand’s law.Herein,we come up with a novel design of heavy-duty lithium metal anode fabricated by partially infusing the three-dimensional(3D)porous graphene aerogel with molten Li.Both electroanalytical measurements and simulations show that the unique electrode architecture brings notable advantages in mediating smooth Li plating/stripping,including reduced local current density,inhibited dendrite growth,buffered volume fluctuation,as well as more efficient Li utilization.Consequently,a remarkable cycling performance in symmetric cells for over 400 cycles(800 h)with an ultrahigh cycling capacity of 15 mAh·cm^(−2) at 15 mA·cm^(−2) is achieved,which,to our best knowledge,has been never seen in literature.LiFePO4 full cells demonstrate a superb rate capability up to 10 C and a prolonged cycling of 1,600 cycles at 2 C with the per-cycle capacity decay of only 0.023%.This study paves the way for the ultimate deployment of lithium metal batteries in real-world applications that require fast charging and deep cycling. | Yong Ma Yuting Gu Ying He Le Wei Yuebin Lian Weiyi Pan Xinjian Li Yanhui Su Yang Peng Zhao Deng Zhongfan Liu | 2022 | Nano Research2022，15，11： | 1 |
| 13 | Exploration on efficient similar sentences extraction 显示文摘 | Yanhui Gu Zhenglu Yang Guandong Xu | 2014 | World Wide Web2014，17，4： | 1 |
| 14 | Exploration on efficient similar sentences extraction显示文摘 | Yanhui Gu Zhenglu Yang Guandong Xu Miyuki Nakano Masashi Toyoda Masaru Kitsuregawa | 2014 | World Wide Web2014，，4： | 1 |
| 15 | Butterfly-wing hierarchical metallic glassy nanostructure for surface enhanced Raman scattering显示文摘The surface-enhanced Raman spectroscopy(SERS)is a technique for the detection of analytes on the surface with an ultrahigh sensitivity down to the atomic-scale,yet the fabrication of SERS materials such as nanoparticles or arrays of coinage metals often involve multiple complex steps with the high cost and pollution,largely limiting the application of SERS.Here,we report a complex hierarchical metallic glassy(MG)nanostructure by simply replicating the surface microstructure of butterfly wings through vapor deposition technique.The MG nanostructure displays an excellent SERS effect and moreover,a superhydrophobicity and self-cleaning behavior.The SERS effect of the MG nanostructure is attributed to the intrinsic nanoscale structural heterogeneities on the MG surface,which provides a large number of hotspots for the localized electromagnetic field enhancement affirmed by the finite-difference time-domain(FDTD)simulation.Our works show that the MG could be a new potential SERS material with low cost and good durability,well extending the functional application of this kind of material. | Hongyu Jiang Jing Li Chengrong Cao Xiaozhi Liu Ming Liu Yutian Shen Yanhui Liu Qinghua Zhang Weihua Wang Lin Gu Baoan Sun | 2019 | Nano Research2019，12，11： | 1 |
| 16 | Evaluation of new IPSS-Molecular model and comparison of different prognostic systems in patients with myelodysplastic syndrome显示文摘A risk-adapted treatment strategy is of crucial importance in patients with myelodysplastic syndromes(MDS).Previous risk prognostic scoring systems did not integrate molecular abnormalities.The new IPSS-Molecular(IPSS-M)model,combing genomic profiling with hematologic and cytogenetic parameters,was recently developed to evaluate the associations with leukemia-free survival(LFS),leukemic transformation,and overall survival(OS).However,it has not yet been widely validated in clinics.This study aims to further validate the prognostic power of IPSS-M based on real-world data and to compare the prognostic value of different scoring systems in patients with MDS.IPSS-M Web calculator was used to calculate a tailored IPSS-M score of the enrolled patient(N=255),and the risk category was defined correspondingly.We next compared the IPSS-M prognostic power to that of IPSS,IPSS-R,and WPSS.We found that IPSS-M risk classification was statistically significant for 3-year OS and LFS.Compared with other tools,IPSS-M was superior in sensitivity and accuracy for 3-year OS and LFS.The mapping C-index between IPSS-R and IPSS-M categories resulted in improved discrimination across the OS,but not LFS and leukemic transformation.The result of different treatment options indicated that allogeneic hematopoietic stem cell transplantation(allo-HSCT)can result in a better OS than those without allo-HSCT.In conclusion,IPSS-M was a valuable tool for risk stratification compared with other risk prognostic scoring systems.However,more studies should be conducted to explore the appropriate treatment options for different groups stratified by IPSS-M. | Jiale Ma Yan Gu Yanhui Wei Xuee Wang Peixuan Wang Chunhua Song Zheng Ge | 2023 | Blood Science2023，5，3： | 0 |
| 17 | Fruit and vegetable intake and the risk of arterial hypertension in China:A prospective cohort study显示文摘Background:Population-based epidemiological evidence regarding the association between fruit and vegetable intake and the incidence of hypertension is inconsistent.This prospective cohort study aimed to investigate the association between fruit and vegetable intake and the risk of new-onset hypertension.Methods:Based on the project of Prediction for Atherosclerotic Cardiovascular Disease Risk in China(China-PAR),58,981 Chinese adults without hypertension at baseline were included.Information on fruit and vegetable intake was collected using a food-frequency questionnaire.Cox proportional hazards models were performed to estimate the hazard ratios(HRs)and 95%confidence intervals(CIs)of incident hypertension.Results:During 640,795 person-years of follow-up,21,008 new cases of hypertension were recorded.Compared with participants in the lowest quintile(Q1)of total fruit and vegetable(TFV)intake,the HRs(95%CIs)of incident hypertension were 0.90(0.86-0.95),0.85(0.81-0.90),0.82(0.78-0.86),and 0.83(0.78-0.88)for the Q2 to Q5 group(ptrend<0.001),respectively.In further analyses categorizing participants according to the recommended intake level(500 g/day),we found that increasing the intake of TFV,even though it was still insufficient for the recommendation,also had a protective effect against the incident hypertension.When considering the intake of fruit or vegetable separately,we found similar trends as the TFV intake.Conclusion:These results suggest that a higher intake of fruit and vegetable is beneficial for preventing hypertension in Chinese adults. | Zhi He Yanhui Jia Jianxin Li IJie Cao Fangchao Liu Hongfan Li Jichun Chen Dongsheng Hu Chong Shen Yingxin Zhao Xiaoqing Liu Ling Yu Jianfeng Huang Xiangfeng Lu Dongfeng Gu Shufeng Chen | 2023 | Chronic Diseases and Translational Medicine2023，9，4： | 0 |
| 18 | Improvement of leaf K^(+) retention is a shared mechanism behind CeO_(2) and Mn_(3)O_(4) nanoparticles improved rapeseed salt tolerance显示文摘Salinity is a global issue limiting efficient agricultural production.Nanobiotechnology has been emerged as an effective approach to improve plant salt tolerance.However,little known is about the shared mechanisms between different nanomaterials-enabled plant salt tolerance.In this study,we found that both PNC[polyacrylic acid coated nanoceria(CeO_(2) nanoparticles)]and PMO(polyacrylic acid coated Mn_(3)O_(4) nanoparticles)nanozymes improved rapeseed salt tolerance.PNC and PMO treated rapeseed plants showed significantly fresh weight,dry weight,higher chlorophyll content,Fv/Fm,and carbon assimilation rate than control plants under salt stress.Results from confocal imaging with reactive oxygen species(ROS)fluorescent dye and histochemical staining experiments showed that the ROS over-accumulation level in PNC and PMO treated rapeseed was significantly lower than control plants under salt stress.Confocal imaging results with K+fluorescent dye showed that significantly higher cytosolic and vacu-olar K^(+) signals were observed in PNC and PMO treated rapeseed than control plants under salt stress.This is further confirmed by leaf K^(+) content data.Furthermore,we found that PNC and PMO treated rapeseed showed significantly lower cytosolic Na^(+) signals than control plants under salt stress.While,compared with significantly higher vacuolar Na^(+) signals in PNC treated plants,PMO treated rapeseed showed significantly lower vacuolar Na^(+) signals than control plants under salt stress.These results are further supported by qPCR results of genes of Na^(+) and K^(+) transport.Overall,our results suggest that besides maintaining ROS homeostasis,improvement of leaf K^(+) retention could be a shared mechanism in nano-improved plant salt tolerance. | Yanhui Li Jin Hu Jie Qi Fameng Zhao Jiahao Liu Linlin Chen Lu Chen Jiangjiang Gu Honghong Wu Zhaohu Li | 2022 | Stress Biology2022，2，1： | 0 |
| 19 | Organoids revealed:morphological analysis of the profound next generation in-vitro model with artificial intelligence显示文摘In modern terminology,“organoids”refer to cells that grow in a specific three-dimensional(3D)environment in vitro,sharing similar structures with their source organs or tissues.Observing themorphology or growth characteristics of organoids through a microscope is a commonly used method of organoid analysis.However,it is difficult,time-consuming,and inaccurate to screen and analyze organoids only manually,a problem which cannot be easily solved with traditional technology.Artificial intelligence(AI)technology has proven to be effective in many biological and medical research fields,especially in the analysis of single-cell or hematoxylin/eosin stained tissue slices.When used to analyze organoids,AI should also provide more efficient,quantitative,accurate,and fast solutions.In this review,we will first briefly outline the application areas of organoids and then discuss the shortcomings of traditional organoid measurement and analysis methods.Secondly,we will summarize the development from machine learning to deep learning and the advantages of the latter,and then describe how to utilize a convolutional neural network to solve the challenges in organoid observation and analysis.Finally,we will discuss the limitations of current AI used in organoid research,as well as opportunities and future research directions. | Xuan Du Zaozao Chen Qiwei Li Sheng Yang Lincao Jiang Yi Yang Yanhui Li Zhongze Gu | 2023 | Bio-Design and Manufacturing2023，6，3： | 0 |
| 20 | Hybrid Neural Network for Automatic Recovery of Elliptical Chinese Quantity Noun Phrases显示文摘In Mandarin Chinese,when the noun head appears in the context,a quantity noun phrase can be reduced to a quantity phrase with the noun head omitted.This phrase structure is called elliptical quantity noun phrase.The automatic recovery of elliptical quantity noun phrase is crucial in syntactic parsing,semantic representation and other downstream tasks.In this paper,we propose a hybrid neural network model to identify the semantic category for elliptical quantity noun phrases and realize the recovery of omitted semantics by supplementing concept categories.Firstly,we use BERT to generate character-level vectors.Secondly,Bi-LSTM is applied to capture the context information of each character and compress the input into the context memory history.Then CNN is utilized to capture the local semantics of n-grams with various granularities.Based on the Chinese Abstract Meaning Representation(CAMR)corpus and Xinhua News Agency corpus,we construct a hand-labeled elliptical quantity noun phrase dataset and carry out the semantic recovery of elliptical quantity noun phrase on this dataset.The experimental results show that our hybrid neural network model can effectively improve the performance of the semantic complement for the elliptical quantity noun phrases. | Hanyu Shi Weiguang Qu Tingxin Wei Junsheng Zhou Yunfei Long Yanhui Gu Bin Li | 2021 | Computers, Materials & Continua2021，，12： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员