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| 1 | Transjugular intrahepatic portosystemic shunt vs endoscopic therapy in preventing variceal rebleeding显示文摘AIM:To compare early use of transjugular intrahepatic portosystemic shunt(TIPS) with endoscopic treatment(ET) for the prophylaxis of recurrent variceal bleeding.METHODS:In-patient data were collected from 190 patients between January 2007 and June 2010 who suffured from variceal bleeding.Patients who were older than 75 years;previously received surgical treatment or endoscopic therapy for variceal bleeding;and complicated with hepatic encephalopathy or hepatic cancer,were excluded from this research.Thirty-five cases lost to follow-up were also excluded.Retrospective analysis was done in 126 eligible cases.Among them,64 patients received TIPS(TIPS group) while 62 patients received endoscopic therapy(ET group).The relevant data were collected by patient review or telephone calls.The occurrence of rebleeding,hepatic encephalopathy or other complications,survival rateand cost of treatment were compared between the two groups.RESULTS:During the follow-up period(median,20.7 and 18.7 mo in TIPS and ET groups,respectively),rebleeding from any source occurred in 11 patients in the TIPS group as compared with 31 patients in the ET group(Kaplan-Meier analysis and log-rank test,P = 0.000).Rebleeding rates at any time point(6 wk,1 year and 2 year) in the TIPS group were lower than in the ET group(Bonferroni correction α' = α/3).Eight patients in the TIPS group and 16 in the ET group died with the cumulative survival rates of 80.6% and 64.9%(Kaplan-Meier analysis and log-rank test c2 = 4.864,P = 0.02),respectively.There was no significant difference between the two groups with respect to 6-wk survival rates(Bonferroni correction α' = α/3).However,significant differences were observed between the two groups in the 1-year survival rates(92% and 79%) and the 2-year survival rates(89% and 64.9%)(Bonferroni correction α' = α/3).No significant differences were observed between the two treatment groups in the occurrence of hepatic encephalopathy(12 patients in TIPS group and 5 in ET group,KaplanMeier analysis and log-rank test,c2 = 3.103,P = 0.08).The average total cost for the TIPS group was higher than for ET group(Wilcxon-Mann Whitney test,52 678 RMB vs 38 844 RMB,P < 0.05),but hospitalization frequency and hospital stay during follow-up period were lower(Wilcxon-Mann Whitney test,0.4 d vs 1.3 d,P = 0.01;5 d vs 19 d,P < 0.05).CONCLUSION:Early use of TIPS is more effective than endoscopic treatment in preventing variceal rebleeding and improving survival rate,and does not increase occurrence of hepatic encephalopathy. | Hui Xue Meng Zhang Jack XQ Pang Fei Yan Ying-Chao Li Liang-Shan Lv Jia Yuan Muna Palikhe Wei-Zhi Li Zhi-Lun Wang | 2012 | World Journal of Gastroenterology2012，18，48： | 17 |
| 2 | Genetic evidence for domestic raccoon dog rabies caused by Arctic-like rabies virus in Inner Mongolia, China显示文摘 | Shao XQ Yan XJ Luo GL | 2011 | Edpidemiol Infect2011，139，4： | 1 |
| 3 | RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism显示文摘 | Sarosi I Yan XQ | 2000 | Proc Natl Acad Sci USA2000，97，4： | 1 |
| 4 | RANK is the intrinsichematopoietic cell surface receptor that controls os-teoclastogenesis and regulation of bone mass andcalcium metabolism 显示文摘 | Li J Sarosi I Yan XQ | 2000 | Proc Natl Acad Sci USA2000，97，4： | 1 |
| 5 | RANK is the intrinsic hematop-obtic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism显示文摘 | Li J Sarosi I Yan XQ | 2000 | Proc Natl Acad Sci USA2000，97，7： | 1 |
| 6 | RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism显示文摘 | Li J Sarosi I Yan XQ | 2000 | Proc Natl Acad Sci USA2000，97，4： | 1 |
| 7 | Disposable reagentless electrochemical immunosensor array based on a biopolymer/sol-gel membrane for simultaneous measurement of several tumor markers 显示文摘 | Wu J Yan F Zhang XQ Yan YT Tang JH Ju HX | 2008 | Clinical Chemistry2008，54，9： | 1 |
| 8 | Effect of naphthalene acetic acid on adventitious root development and associated physiological changes in stem cutting of Hemarthria compressa 显示文摘 | Yan YH Li JL Zhang XQ | 2014 | PLoS One2014，9，3： | 1 |
| 9 | Chronic exposure to retroviral vector encoded MGDF(mpl-ligand) induces lineage-specific growth and differentiaton of megakaryocytes in mice显示文摘 | Yan XQ Lacey D Fletcher F | 1995 | Blood1995，96，： | 1 |
| 10 | Apolipoprotein A5 gene polymorphism 1131T > C : association with plasma lipids and type 2 diabetes mellitus with coronary heart disease in Chinese显示文摘 | Yan SK Cheng XQ Song YH | 2005 | Clin Chem2005，43，： | 1 |
| 11 | Burden of gastroesophageal reflux disease in Shanghai,China显示文摘 | Wang R Yan X Ma XQ | 2009 | Digestive and Liver disease2009，41，： | 1 |
| 12 | Mobilization of long - term hematopoietic reconstituting cells in mice by the combination of stem cell factor plus granulocyte colony-stimularing factor 显示文摘 | Yan XQ Briddell R Hartley C | 1994 | Blood1994，84，3： | 1 |
| 13 | Mechanochemical modification ofkaolin surfaces for immobilization and delivery of pesticides in alginate -chitosan composite beads 显示文摘 | YAN H Q CHEN XQ WUTT | 2014 | Polym Bull2014，71，： | 1 |
| 14 | Burden of Gastroesophageal Reflux Disease in Shanghai, China 显示文摘 | Wang R Yan X Ma XQ | 2009 | Digestive and Liver Disease2009，41，： | 1 |
| 15 | Expression of SOCS-1,3 induced by Chlamydia trachomatis-infected Hela229 显示文摘 | Wei XQ Cheng W Yan J | 2004 | Journal of Central South University ( medical sciences)2004，29，6： | 1 |
| 16 | Down-regulation of miRNA-30a in human plasma is a novel marker for breast cancer显示文摘 | Zeng RC Zhang W Yan XQ | 2013 | Med 0neol2013，30，1： | 1 |
| 17 | Growth of SnO2 nanowires with uniform branched structures显示文摘 | Wang JX Liu DF Yan XQ | 2004 | Solid State Communications2004，，130： | 1 |
| 18 | Oleanolic acid inhibits hypertrophic scarring in the rabbit ear model显示文摘 | Wei YJ Yan XQ Ma L | | 0，，05： | 1 |
| 19 | Application of C12multi-tumor protein chip in the diagnosis of gastrointestinal eaneer: results of 329 surgical patients and suggestions for improvement显示文摘 | Yang XQ Yan L Chen C | 2009 | Hepatogastroenterology2009，56，9495： | 1 |
| 20 | A crack tip displacement discontinuity element显示文摘 | YAN XQ | 2004 | Mechanics Research Communications2004，31，6： | 1 |
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