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| 1 | The ChinaMAP analytics of deep whole genome sequences in 10,588 individuals显示文摘Metabolic diseases are the most common and rapidly growing health issues worldwide.The massive population-based human genetics is crucial for the precise prevention and intervention of metabolic disorders.The China Metabolic Analytics Project(ChinaMAP)is based on cohort studies across diverse regions and ethnic groups with metabolic phenotypic data in China.Here,we describe the centralized analysis of the deep whole genome sequencing data and the genetic bases of metabolic traits in 10,588 individuals from the ChinaMAP.The frequency spectrum of variants,population structure,pathogenic variants and novel genomic characteristics were analyzed.The individual genetic evaluations of Mendelian diseases,nutrition and drug metabolism,and traits of blood glucose and BMI were integrated.Our study establishes a large-scale and deep resource for the genetics of East Asians and provides opportunities for novel genetic discoveries of metabolic characteristics and disorders. | Yanan Cao Lin Li Min Xu Zhimin Feng Xiaohui Sun Jieli Lu Yu Xu Peina Du Tiange Wang Ruying Hu Zhen Ye Lixin Shi Xulei Tang Li Yan Zhengnan Gao Gang Chen Yinfei Zhang Lulu Chen Guang Ning Yufang Bi Weiqing Wang The ChinaMAP Consortium | 2020 | Cell Research2020，30，9： | 20 |
| 2 | On-the-fly active learning of interpretable Bayesian force fields for atomistic rare events显示文摘Machine learned force fields typically require manual construction of training sets consisting of thousands of first principles calculations,which can result in low training efficiency and unpredictable errors when applied to structures not represented in the training set of the model.This severely limits the practical application of these models in systems with dynamics governed by important rare events,such as chemical reactions and diffusion.We present an adaptive Bayesian inference method for automating the training of interpretable,low-dimensional,and multi-element interatomic force fields using structures drawn on the fly from molecular dynamics simulations.Within an active learning framework,the internal uncertainty of a Gaussian process regression model is used to decide whether to accept the model prediction or to perform a first principles calculation to augment the training set of the model.The method is applied to a range of single-and multi-element systems and shown to achieve a favorable balance of accuracy and computational efficiency,while requiring a minimal amount of ab initio training data.We provide a fully opensource implementation of our method,as well as a procedure to map trained models to computationally efficient tabulated force fields. | Jonathan Vandermause Steven B.Torrisi Simon Batzner Yu Xie Lixin Sun Alexie M.Kolpak Boris Kozinsky | 2020 | npj Computational Materials2020，，1： | 17 |
| 3 | Study on the antiulcer effects of Veronicastrum axillare on gastric ulcer in rats induced by ethanol based on tumor necrosis factor-α(TNF-α)and endothelin-1(ET-1)显示文摘Objective:To assess whether Veronicastrum axillare(V.axillare)can ameliorate ethanol-induced gastric mucosal lesions in rats,reduce the production of pro-inflammatory cytokines,suppress apoptosis and improve local microcirculation disturbances.Methods:Totally 48 male Sprague-Dawley rats were randomly divided into six groups,eight rats in each group.Rats in the normal group and the model group were administered with 0.9%normal saline respectively.Rats in the positive group and ranitidine group were administered with 0.18%ranitidine suspension by intragastric administration respectively.Those in the high dose V.axillare group,the medium dose V.axillare group and the low dose V.axillare group were administrated with V.axillare at the daily dose of 2.8 g/kg,1.4 g/kg and 0.7 g/kg by intragastric administration.Gastric mucosal lesions were produced by intragastric administration of absolute ethanol.Water extract of V.axillare was successively injected for 14 d and last day was injected 1 h before ethanol administration.Gastric mucosal ulcer index and ulcer inhibitory rate were counted by improved Guth methods.The tissue sections were made for pathological histology analysis.Also,we measured the concentrations of tumor necrosis factor-α(TNF-α)and endothelin-1(ET-1)in gastric mucosal,as an index of the pro-inflammatory cytokines,apoptosis and local microcirculation.Besides,the mRNA contents of TNF-αand ET-1 were measured to verify effects on gene expression by real-time fluorescent quantitative PCR.Results:Water extract of V.axillare significantly ameliorated the gastric mucosal lesions induced by ethanol administration(P<0.01).Pro-inflammatory cytokines,TNF-a and ET-1 were increased after ethanol administration and significantly reduced by water extract of V.axillare.The expressions of TNF-αand ET-1 mRNA were also be inhibited by water extract of V.axillare.Conclusion:Current evidences show water extract of V.axillare is effective for defending against ethanol-induced gastric mucosal lesions,significantly inhibiting the production of proinflammatory cytokines and the expressions of TNF-αand ET-1 mRNA,which may be useful for inhibiting apoptosis and improving local microcirculation. | Yong Du Weichun Zhao Leilei Lu Jiayan Zheng Xishi Hu Zhehan Yu Lixin Zhu | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，12： | 13 |
| 4 | Discussion on the relationship between the Yanshanian Movement and cratonic destruction in North China显示文摘The relationship between the Yanshanian Movement, destruction of the North China Craton(NCC), and subduction of the western Pacific plate is crucial to reconstructing the middle-late Mesozoic tectonic evolution of the eastern Asian continent and margin. The Yanshanian Movement was a globally important change in crustal tectonics during the Middle-Late Jurassic.Previous research has systematically studied the formation and evolution of the Yanshanian Movement, focusing on the timing and location of tectonic movements, and the sedimentary and volcanic strata. However, the question of whether the tectonic activity occurred globally, and the characteristics of the Yanshanian Movement remain debated. The main argument is that if a tectonic movement can only be characterized by a regional or local disconformity, and if the tectonic movement occurred in an intracontinental setting, with extensive deformation but with no disconformity despite volcanic eruptions and magmatic intrusions, accompanied by changes in crustal structure and composition, should it be defined as a tectonic event or process? This question requires further analysis. The main aim of this study is to distinguish whether the Yanshanian Movement is a local feature of the eastern Asian continent, or a global tectonic event related to subduction of the Pacific Plate. In this paper, based on previous research, we discuss the spatial and temporal evolution of the Yanshanian Movement, the controlling tectonic mechanisms, and its relationship to the reactivation and destruction of the NCC and the subduction of the western Paleo-Pacific slab.We emphasize that the Yanshanian Movement in the Middle-Late Jurassic is distinct from the lithospheric thinning responsible for Early Cretaceous extension and magmatism related to the destruction of the NCC. The various tectonic stages were constrained by different dynamics and tectonic settings, or by different tectonic events and processes. Therefore, it is possible that the deformation and reactivation of the NCC contributed to its destruction, in addition to lithospheric thinning. Finally, we discuss whether the Yanshanian Movement was associated with the destruction of the NCC. | Yu WANG Lixin SUN Liyun ZHOU Yueting XIE | 2018 | Science China Earth Sciences2018，61，5： | 13 |
| 5 | SDOG-based multi-scale 3D modeling and visualization on global lithosphere显示文摘The structure of global lithosphere is very important to the scientific researches of tectonic movement, geodynamic process, mantle convection, resource exploration, and disaster prevention and reduction. Three-dimensional (3D) spatial modelling and visualization is an effective tool for lithosphere researches. However, both the isoline/profile methods and the Euclidean-based 3D modelling methods cannot meet the requirement of real 3D modeling of global lithosphere, whereas the recently developed global 3D grid methods have some defects on grid design, such as grid shrinkage, overlapping, non-orthogonality, and nonlatitude-longitude consistency. In this paper, Spheroid Degenerated-Octree Grid (SDOG), a non-overlapping, non-shrinking, orthogonal, latitude-longitude consistent grid in the spheroidal manifold space, was chosen as the basic grid for global lithosphere 3D modeling and visualization. The SDOG-based methods of spatial representation and modelling of lithosphere were proposed. A multi-scale model of lithosphere was designed, and the multi-scale modeling and multi-mode visualization were realized at the full advantages of SDOG in multi-hierarchical and multi-resolution and the properties of lithosphere in multi-semantic. It shows that (1) the SDOG-based method has not only overcome the defects of the current global 3D grid, but also reflected the spherical features of lithosphere more realistically and naturally than the traditional methods, providing a novel solution for global modeling, numeric simulating, and data sharing of lithosphere; and (2) more detailed plates division, more precise geo-layer structure, plates boarder and surface concave-convex, and more rich lithosphere properties are revealed as the scale-model moves on. | YU JieQing WU LiXin ZI GuoJie GUO ZengZhang | 2012 | Science China Earth Sciences2012，55，6： | 11 |
| 6 | Distributed Adaptive Cooperative Tracking of Uncertain Nonlinear Fractional-order Multi-agent Systems显示文摘In this paper, the leader-following tracking problem of fractional-order multi-agent systems is addressed. The dynamics of each agent may be heterogeneous and has unknown nonlinearities. By assumptions that the interaction topology is undirected and connected and the unknown nonlinear uncertain dynamics can be parameterized by a neural network, an adaptive learning law is proposed to deal with unknown nonlinear dynamics, based on which a kind of cooperative tracking protocols are constructed. The feedback gain matrix is obtained to solve an algebraic Riccati equation. To construct the fully distributed cooperative tracking protocols, the adaptive law is also adopted to adjust the coupling weight. With the developed control laws,we can prove that all signals in the closed-loop systems are guaranteed to be uniformly ultimately bounded. Finally, a simple simulation example is provided to illustrate the established result. | Zhitao Li Lixin Gao Wenhai Chen Yu Xu | 2020 | IEEE/CAA Journal of Automatica Sinica2020，7，1： | 9 |
| 7 | SHRIMP U-Pb Zircon Age of the Ka'erjiao Intrusion in the Sawur Region in West Junggar,Xinjiang显示文摘摘要:酸侵入在 Sawur 区域是普遍的, Xinjiang。Ka'erjiao 侵入主要由钠长石花岗石斑岩, K 长石花岗石斑岩, ivernite 和花岗石斑岩组成。在 Sawur 区域是在岩浆侵入和爆发之间的一个过渡产品, Ka'erjiao 侵入在未期被形成对开始晚含碳作为早二叠由标明日期的 SHRIMP U-Pb 锆石决定了,与 302.6 | ZHOU Taofa TAN Lugui FAN Yu YUAN Feng YANG Wenping HE Lixin YUE Shucang | 2007 | Acta Geologica Sinica(English Edition)2007，81，2： | 9 |
| 8 | Effectiveness of Catch-Up Vaccinations after COVID-19 Containment--China,2020显示文摘Introduction:In the early stages of the coronavirus disease 2019(COVID-19)epidemic in China,the highest level of public health emergency response(Level 1 Response)was launched in all province-level administrative divisions(PLADs)across the country.Provision of vaccination services was selectively suspended due to the physical distancing and gathering restrictions required of Level 1 Response.The purpose of this paper is to evaluate the impact of COVID-19 on vaccination services and the effectiveness of selective vaccination service suspension and catch-up vaccinations in China.Methods:Vaccine doses administered,routine vaccination coverage levels,catch-up vaccine doses administered,and coverage levels after the catch-up campaign were determined from individual vaccination records in sampled clinics,standard routine immunization administrative coverage reports,and catch-up vaccination activity reports submitted by PLADs between October 2019 and October 2020.Results:National Immunization Program(NIP)and non-NIP vaccine doses administered in sampled clinics decreased by 80% and 90%,respectively,compared with doses administered before the COVID-19 pandemic.Coverage with the birth dose of hepatitis B vaccine(HepB1)and the Bacillus Calmette-Guérin vaccine(BCG)—two vaccinations recommended to continue throughout the epidemic due to their timecritical nature—were maintained at over 85%,while coverage of other NIP vaccines decreased to below 60%by February 2020.Catch-up vaccination coverage of the 29 PLADs,excluding Xinjiang and Xizang(Tibet),began in April 2020 and exceeded 90%;Hubei catch-up coverage was 95% by October 2020.Conclusions and Implications for Public Health Practice:The COVID-19 pandemic had a great impact on China’s vaccination services.During the epidemic and time of local transmission of the coronavirus,HepB1,BCG,rabies vaccine for postexposure prophylaxis,and tetanus antitoxin(TAT)for wound prophylaxis were maintained at high levels.Of the 69 million vaccine doses postponed during the time of local transmission of the coronavirus,94% were administered in the catch-up campaign.China’s pandemic immunization practices may provide evidence for other countries’immunization programs. | Jing Wu Wenzhou Yu Lei Cao Lingsheng Cao Lance Rodewald Jiakai Ye Yifan Song Li Li Xiaoxue Liu Ning Wen Fuzhen Wang Lixin Hao Yixing Li Hui Zheng Keli Li Chao Ma Dan Wu Yanmin Liu Guomin Zhang Zhijie An Huaqing Wang Zundong Yin | 2020 | China CDC weekly2020，2，50： | 6 |
| 9 | DeST 3.0:A new-generation building performance simulation platform显示文摘Buildings contribute to almost 30%of total energy consumption worldwide.Developing building energy modeling programs is of great significance for lifecycle building performance assessment and optimization.Advances in novel building technologies,the requirements of high-performance computation,and the demands for multi-objective models have brought new challenges for building energy modeling software and platforms.To meet the increasing simulation demands,DeST 3.0,a new-generation building performance simulation platform,was developed and released.The structure of DeST 3.0 incorporates four simulation engines,including building analysis and simulation(BAS)engine,HVAC system engine,combined plant simulation(CPS)engine,and energy system(ES)engine,connected by air loop and water loop balancing iterations.DeST 3.0 offers numerous new simulation features,such as advanced simulation modules for building envelopes,occupant behavior and energy systems,cross-platform and compatible simulation kernel,FMI/FMU-based co-simulation functionalities,and high-performance parallel simulation architecture.DeST 3.0 has been thoroughly evaluated and validated using code verification,inter-program comparison,and case-study calibration.DeST 3.0 has been applied in various aspects throughout the building lifecycle,supporting building design,operation,retrofit analysis,code appliance,technology adaptability evaluation as well as research and education.The new generation building simulation platform DeST 3.0 provides an efficient tool and comprehensive simulation platform for lifecycle building performance analysis and optimization. | Da Yan Xin Zhou Jingjing An Xuyuan Kang Fan Bu Youming Chen Yiqun Pan Yan Gao Qunli Zhang Hui Zhou Kuining Qiu Jing Liu Yan Liu Honglian Li Lei Zhang Hong Dong Lixin Sun Song Pan Xiang Zhou Zhe Tian Wenjie Zhang Ruhong Wu Hongsan Sun Yu Huang Xiaohong Su Yongwei Zhang Rui Shen Diankun Chen Guangyuan Wei Yixing Chen Jinqing Peng | 2022 | Building Simulation2022，15，11： | 5 |
| 10 | Experimental research on rotating detonation with liquid hypergolic propellants显示文摘This paper describes experimental research into the initiation and propagation of rotating detonation for liquid Nitrogen TetrOxide(NTO) and liquid MonoMethylHydrazine(MMH).An annular rocket-type combustor without nozzle was designed to investigate detonation combustion. The propellants were injected through unlike impingement injectors. The combustion flame fronts and pressure waves were detected using optical diagnostics and dynamic pressure sensors,respectively. The propagation of rotating detonation was established spontaneously by increasing the mass flow rate of propellants. The velocity of propagation of the flame fronts and pressure waves was nearly equal and reaches supersonic speed. Two different detonation combustion patterns are present, single wave mode and double waves mode. And in double waves mode, the two detonation waves are always counter-rotating. The possibility of rotating detonation initiation in a combustor with nozzle was also checked. Stable rotating detonation can be initialized and sustained at similar operating conditions. | Shuaijie XUE Hongjun LIU Lixin ZHOU Weidong YANG Hongbo HU Yu YAN | 2018 | Chinese Journal of Aeronautics2018，31，12： | 5 |
| 11 | The Tibetan Plateau Surface–Atmosphere Coupling System and Its Weather and Climate Effects: The Third Tibetan Plateau Atmospheric Science Experiment显示文摘The Tibetan Plateau(TP) is a key area affecting forecasts of weather and climate in China and occurrences of extreme weather and climate events over the world. The China Meteorological Administration, the National Natural Science Foundation of China, and the Chinese Academy of Sciences jointly initiated the Third Tibetan Plateau Atmospheric Science Experiment(TIPEX-Ⅲ) in 2013, with an 8–10-yr implementation plan. Since its preliminary field measurements conducted in 2013, routine automatic sounding systems have been deployed at Shiquanhe, Gaize, and Shenzha stations in western TP, where no routine sounding observations were available previously. The observational networks for soil temperature and soil moisture in the central and western TP have also been established. Meanwhile, the plateau-scale and regional-scale boundary layer observations, cloud–precipitation microphysical observations with multiple radars and aircraft campaigns, and tropospheric–stratospheric air composition observations at multiple sites, were performed. The results so far show that the turbulent heat exchange coefficient and sensible heat flux are remarkably lower than the earlier estimations at grassland, meadow, and bare soil surfaces of the central and western TP. Climatologically, cumulus clouds over the main body of the TP might develop locally instead of originating from the cumulus clouds that propagate northward from South Asia. The TIPEX-Ⅲ observations up to now also reveal diurnal variations, macro-and microphysical characteristics, and water-phase transition mechanisms, of cumulus clouds at Naqu station. Moreover, TIPEX-Ⅲ related studies have proposed a maintenance mechanism responsible for the Asian 'atmospheric water tower' and demonstrated the effects of the TP heating anomalies on African, Asian, and North American climates. Additionally, numerical modeling studies show that the Γ distribution of raindrop size is more suitable for depicting the TP raindrop characteristics compared to the M–P distribution, the overestimation of sensible heat flux can be reduced via modifying the heat transfer parameterization over the TP, and considering climatic signals in some key areas of the TP can improve the skill for rainfall forecast in the central and eastern parts of China. Furthermore, the TIPEX-Ⅲ has been promoting the technology in processing surface observations, soundings, and radar observations, improving the quality of satellite retrieved soil moisture and atmospheric water vapor content products as well as high-resolution gauge–radar–satellite merged rainfall products, and facilitating the meteorological monitoring, forecasting, and data sharing operations. | Ping ZHAO Yueqing LI Xueliang GUO Xiangde XU Yimin LIU Shihao TANG Wenming XIAO Chunxiang SHI Yaoming MA Xing YU Huizhi LIU La JIA Yun CHEN Yanju LIU Jian LI Dabiao LUO Yunchang CAO Xiangdong ZHENG Junming CHEN An XIAO Fang YUAN Donghui CHEN Yang PANG Zhiqun HU Shengjun ZHANG Lixin DONG Juyang HU Shuai HAN Xiuji ZHOU | 2019 | Journal of Meteorological Research2019，33，3： | 4 |
| 12 | Influence of microbial community structure of seed sludge on the properties of aerobic nitrifying granules显示文摘In order to evaluate the influence of microbial community structure of seed sludge on the properties of aerobic nitrifying granules, these granules were cultivated with different seed sludge, and the variation of microbial community and dominant bacterial groups that impact the nitrogen removal efficiency of the aerobic nitrifying granules were analyzed and identified using 16 s rDNA sequence and denaturing gradient gel electrophoresis(DGGE) profiles. The results presented here demonstrated that the influence of the community structure of seed sludge on the properties of aerobic nitrifying granules was remarkable, and the granules cultivated by activated sludge from a beer wastewater treatment plant showed better performance, with a stable sludge volume index(SVI) value of 20 m L/g, high extracellular polymeric substance(EPS) content of 183.3 mg/L, high NH4+-N removal rate of 89.42% and abundant microbial population with 10 dominant bacterial groups. This indicated that activated sludge with abundant communities is suitable for use as seed sludge in culturing aerobic nitrifying granules. | Zhiwei Song Ting Li Qiuxu Wang Yu Pan Lixin Li | 2015 | Journal of Environmental Sciences2015，27，9： | 4 |
| 13 | An Examination of the Predictability of Tropical Cyclone Genesis in High-Resolution Coupled Models with Dynamically Downscaled Coupled Data Assimilation Initialization显示文摘Predicting tropical cyclone(TC)genesis is of great societal importance but scientifically challenging.It requires fineresolution coupled models that properly represent air−sea interactions in the atmospheric responses to local warm sea surface temperatures and feedbacks,with aid from coherent coupled initialization.This study uses three sets of highresolution regional coupled models(RCMs)covering the Asia−Pacific(AP)region initialized with local observations and dynamically downscaled coupled data assimilation to evaluate the predictability of TC genesis in the West Pacific.The APRCMs consist of three sets of high-resolution configurations of the Weather Research and Forecasting−Regional Ocean Model System(WRF-ROMS):27-km WRF with 9-km ROMS,and 9-km WRF with 3-km ROMS.In this study,a 9-km WRF with 9-km ROMS coupled model system is also used in a case test for the predictability of TC genesis.Since the local sea surface temperatures and wind shear conditions that favor TC formation are better resolved,the enhanced-resolution coupled model tends to improve the predictability of TC genesis,which could be further improved by improving planetary boundary layer physics,thus resolving better air−sea and air−land interactions. | Mingkui LI Shaoqing ZHANG Lixin WU Xiaopei LIN Ping CHANG Gohkan DANABASOGLU Zhiqiang WEI Xiaolin YU Huiqin HU Xiaohui MA Weiwei MA Haoran ZHAO Dongning JIA Xin LIU Kai MAO Youwei MA Yingjing JIANG Xue WANG Guangliang LIU Yuhu CHEN | 2020 | Advances in Atmospheric Sciences2020，37，9： | 4 |
| 14 | Salt-related structure and deformation mechanism of the Middle-Lower Cambrian in the middle-west parts of the Central Uplift and adjacent areas of the Tarim Basin显示文摘The salt beds of the Middle-Lower Cambrian are widespread in the middle-west parts of the Central Uplift and adjacent areas, the Tarim Basin. This paper presents the results of seismic interpretation and drilling data analysis, which discovered that the salt beds were formed in an old geologic age, deeply buried, with relatively small scaled flowing and gathering and uneven distribution. As the regional detachment layers, the salt sequences considerably control the structural deformation of the up-salt Paleozoic, forming a series of hydrocarbon traps. In due course, the salt beds of the Middle-Lower Cambrian provide excellent cap rocks and trap conditions; thus the value of exploring hydrocabon reservoir in the target strata of the sub-salt Sinian- Cambrian is greatly increased. Research has shown that the salt-related structures of the Middle-Lower Cambrian in the area mainly exist in the form of salt pillow, salt roller, up-salt anticline, salt diapir, assemblage of the salt arch and up-salt fault-block, assemblage of basement fault and salt anticline, assemblage of the basement fault-block and salt dome, assemblage of salt detachment and fault-related fold, and assemblage of basement fault-block, salt arch and up-salt imbricated thrusts. The evolution and deformation mechanisms of the salt-related structures are controlled largely by basement faulting, compressional shortening, plastic flowing and gathering, superstratum gravitation, and up-salt faulting and detaching. They are distributed in rows or belts along basement faults or fault block belts. | TANG LiangJie HUANG TaiZhu QIU HaiJun QI LiXin YANG Yong XIE DaQing YU YiXin ZHAO Zhao CHEN ShuPing | 2012 | Science China Earth Sciences2012，55，7： | 3 |
| 15 | CSF-Based Analysis for Identification of Potential Serum Biomarkers of Neural Tube Defects显示文摘The protein composition of cerebrospinal fluid(CSF) in neural tube defects(NTDs) remains unknown. We investigated the protein composition of CSF from 9 infants with NTDs using isobaric tags for relative and absolute quantitation(iTRAQ). We identified 568 proteins in the CSF of infants with spina bifida, which is the most common type of NTD. Among these, 18 proteins were associated with neural tube closure in the CSF during human embryonic neurulation and 5 were involved in NTDs. Based on these results, an animal model was further utilized to investigate early serum biomarkers for NTDs.We found that the myristoylated alanine-rich C-kinase substrate, Kunitz-type protease inhibitor 2, andapolipoprotein B-100 protein levels were decreased in both embryos and the sera of pregnant Sprague-Dawley rats carrying embryos with NTDs. CSF proteins may be useful in the discovery of potential serum biomarkers for NTDs. | Xinyu Yan Lixin Mai Changchun Lin Wenji He Gengsheng Yin Jiakang Yu Lian Huang Sanqiang Pan | 2017 | Neuroscience Bulletin2017，33，4： | 3 |
| 16 | Detection and Initial Response to a Type 2 Vaccine-Derived Poliovirus—Sichuan Province,China,2019显示文摘What is already known about this topic?After the type 2 strain of the live,attenuated poliovirus vaccine was withdrawn globally in 2016,any identification of a type 2 poliovirus is a Public Health Emergency of International Concern.A vaccinederived type 2 poliovirus(VDPV2)was identified in Sichuan,prompting an urgent,comprehensive investigation and response.What is added by this report?Type 2 monovalent,live,attenuated oral poliovirus vaccine(mOPV2)is being used to respond to the numerous VDPV2 outbreaks seen around the world.In contrast,the response in Sichuan used Sabin strain inactivated poliovirus(sIPV)to stop circulation of the VDPV2.In the 6 months following the vaccination response,there have been no VDPV2s detected in Sichuan,despite extensive search.What are the implications for public health practices?Further search for the VDPV2 must continue in order to determine whether transmission has been stopped.The ongoing investigation and response to the Sichuan VDPV2 is providing evidence to the Global Polio Eradication Initiative on managing VDPV2 outbreaks. | Jiushun Zhou Ning Wen Yong Zhang Qi Qi Chunxiang Fan Dongmei Yan Xiaoping Zhu Lixin Hao Shuangli Zhu Yu Liu Xiaozhen Ma Chao Ma Lei Nan Yong Chen Qianli Ma Cheng Wang Kun Deng Lei Cao Ge Shao Xianxiang Ding Hong Yang Zhijie An Lance ERodewald Aiqiang Xu Huaqing Wang Zijian Feng Zundong Yin Xianping Wu Wenbo Xu | 2020 | China CDC weekly2020，2，11： | 3 |
| 17 | More on stability of almost surjective ε-isometries of Banach spaces显示文摘Let X and Y be two Banach spaces,and f:X→Y be a standard ε-isometry for some ε >= 0.In this paper,by using a recent theorem established by Cheng et al.(2013–2015),we show a sufficient condition guaranteeing the following sharp stability inequality of f:There is a surjective linear operator T:Y→X of norm one so that ||T f(x)-x||<= 2ε,for all x∈X.As its application,we prove the following statements are equivalent for a standard ε-isometry f:X→Y:(i)lim inf_(t→∞) dist(ty,f(X))/|t|<1/2,for all y∈S_Y;(ii)τ(f)≡sup_(y∈S_Y) lim inf_(t→∞) dist(ty,f(X))/|t|=0;(iii)there is a surjective linear isometry U:X→Y so that || f(x)-Ux||<= 2ε,for all x∈X.This gives an affirmative answer to a question proposed by Vestfrid(2004,2015). | CHENG LiXin SHEN QinRui ZHANG Wen ZHOU Yu | 2017 | Science China Mathematics2017，60，2： | 3 |
| 18 | Evaluating the emission status of light-duty gasoline vehicles and motorcycles in Macao with real-world remote sensing measurement显示文摘Roadside remote sensing measurement was used to explore the real-world emission status of light duty gasoline vehicles(LDGVs) and motorcycles in Macao. Both fuel-based and distance-based emission factors were derived using the mass balance method. The emission concentration profile of LDGVs illustrated the benefits of tightening emission standards at the source country or region of import. The distance-based emission factors for CO, HC and NOx of LDGVs registered before 2000 were 8.00, 1.04 and 1.36 g/km,respectively. The distance-based emission factors for CO, HC and NOx of LDGVs registered in or after 2000 were 1.16, 0.15 and 0.18 g/km, respectively. The fuel-based CO emission factors of light duty motorcycles(LDMCs) and heavy duty motorcycles(HDMCs) registered before 2000 were about 10 times higher than those of LDGVs of the same age group. As the emissions of LDGVs decreased more quickly after 2000, the gap widens for newer vehicles.The distance-based HC emission factors of LDMCs and HDMCs registered before 2000 were4.81 and 2.91 g/km, respectively. The distance-based HC emission factors of LDMCs and HDMCs registered in or after 2000 were 3.52 and 0.93 g/km, respectively. The poor emission performance of motorcycles and their larger share in the traffic flow will cause them to be the major contributor to traffic CO and HC emissions. LDMCs, especially two-stroke models,should be the priority for vehicle emission control efforts in Macao. | Yu Zhou Ye Wu Shaojun Zhang Lixin Fu Jiming Hao | 2014 | Journal of Environmental Sciences2014，26，11： | 3 |
| 19 | The impact of transportation control measures on emission reductions during the 2008 Olympic Games in Beijing, China显示文摘 | Yu Zhou Ye Wu Liu Yang Lixin Fu Kebin He Shuxiao Wang Jiming Hao Jinchuan Chen Chunyan Li | 2009 | Atmospheric Environment2009，，3： | 2 |
| 20 | Sand storms:CFD analysis of Reynolds stress and collision stress of particles near sand bed显示文摘Sand storm is a serious environmental threat to humans.Sand particles are transported by saltation and suspension,causing soil erosion in one place and deposition in another.In order to prevent and predict sand storms,the causes and the manners of particle motions must be studied in detail.In this paper a standard k-ε model is used for the gas phase simulation and the discrete element method(DEM) is used to predict the movements of particles using an in-house procedure.The data are summarized in an Eulerian-Eulerian regime after simulation to get the statistical particle Reynolds stress and particle collision stress.The results show that for the current case the Reynolds stress and the air shear stress predominate in the region 20-250 mm above the initial sand bed surface.However,in the region below 3 mm,the collision stress must be taken into account in predicting particle movement. | Yu Zhang Jiecheng Yang Dayou Liu Xiaolin Wei Lixin Yu | 2010 | Particuology2010，8，4： | 2 |
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