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| 1 | Magnetic resonance elastography is accurate in detecting advanced fibrosis in autoimmune hepatitis显示文摘To assess the value of magnetic resonance elastography(MRE) in detecting advanced fibrosis/cirrhosis in autoimmune hepatitis(AIH).METHODS In this retrospective study, 36 patients(19 treated and 17 untreated) with histologically confirmed AIH and liver biopsy performed within 3 mo of MRE were identified at a tertiary care referral center. Liver stiffness(LS) with MRE was calculated by a radiologist, and inflammation grade and fibrosis stage in liver biopsy was assessed by a pathologist in a blinded fashion. Two radiologistsevaluated morphological features of cirrhosis on conventional magnetic resonance imaging(MRI). Accuracy of MRE was compared to laboratory markers and MRI for detection of advanced fibrosis/cirrhosis.RESULTS Liver fibrosis stages of 0, 1, 2, 3 and 4 were present in 4, 6, 7, 6 and 13 patients respectively. There were no significant differences in distribution of fibrosis stage and inflammation grade between treated and untreated patient groups. LS with MRE demonstrated stronger correlation with liver fibrosis stage in comparison to laboratory markers for chronic liver disease(r = 0.88 vs-0.48-0.70). A trend of decreased mean LS in treated patients compared to untreated patients was observed(3.7 k Pa vs 3.84 k Pa) but was not statistically significant. MRE had an accuracy/sensitivity/specificity/positive predictive value/negative predictive value of 0.97/90%/100%/100%/90% and 0.98/92.3%/96%/92.3%/96% for detection of advanced fibrosis and cirrhosis, respectively. The performance of MRE was significantly better than laboratory tests for detection of advanced fibrosis(0.97 vs 0.53-0.80, P < 0.01), and cirrhosis(0.98 vs 0.58-0.80, P < 0.01) and better than conventional MRI for diagnosis of cirrhosis(0.98 vs 0.78, P = 0.002).CONCLUSION MRE is a promising modality for detection of advanced fibrosis and cirrhosis in patients with AIH with superior diagnostic accuracy compared to laboratory assessment and MRI. | Jin Wang Neera Malik Meng Yin Thomas C Smyrk Albert J Czaja Richard L Ehman Sudhakar K Venkatesh | 2017 | World Journal of Gastroenterology2017，23，5： | 15 |
| 2 | RESEARCH ON THE EVALUATION METHOD OF FRICTION AND LUBRICATION IN DEEP DRAWING显示文摘The deformation characteristic of bland in deep drawing is discussed. It is pointed out that the friction and lubrication conditions in for drawing are different from that in mechanical motion or machine work or other plastic process. The common test methods in laboratories are analyzed. It shows that though all those test methods can test the friction coefficient, the probe test method is most suitable for the research of friction and lubrication and the process in deep drawing, for this method is identical with the actual work condition either from the test principle or deformation status of the blank. Last the successful application in the deep drawing simulator newly developed the the probe method are intro- duced in detail. | D. N. He, X. F. Yin, H. Z. Thao, D. L*, X. Y. Ruan, J. L. Cheng and J. Y. Jiang 1) Shanghai Jiao Tong University, National Die & Mold CAD E. R. C, Shanghai 200030, China 2) Shanghai Vopkswagen Automotive Company Ltd., Shanghai 201805, China Manuscript re | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，2： | 13 |
| 3 | A novel XPF-357A 〉 C polymorphism predicts risk and recurrence of bladder cancer(摘要)显示文摘 | Wang, M Yuan, L Wu, D Zhang, Z Yin, C Fu, G Wei, Q | 2010 | 南京医科大学学报(自然科学版)2010，30，7： | 5 |
| 4 | Combined MEDV-GA-MLR method for QSAR of three panels of steroids,dipeptides and COX-2 inhibitors显示文摘 | Liu S Yin C Wang L | 2002 | J Chem Inf Comput Sci2002，42，： | 1 |
| 5 | Synthesis,structure,and photoluminescence of very thin and wide alpha silicon nitride (α-Si3N4) single-crystalline nanobelts显示文摘 | YIN L W BANDO Y ZHU Y C | 2003 | Appl Phys Lett2003，83，17： | 1 |
| 6 | Removal of phosphateby mesoporous ZrO2显示文摘 | Liu H L Sun X F Yin C Q | 2008 | J Hazard Mater2008，151，23： | 1 |
| 7 | Changes in weed community diversity of maize crops due to long-term fertilization显示文摘 | YIN L C CAI Z C ZHONG W H | 2006 | Crop Protection2006，25，： | 1 |
| 8 | Study on combined control of regenerative braking and antilock braking system for hy- brid electric vehicles 显示文摘 | Peng D Zhang Y Yin C L | 2008 | International Journal of Automo- tive Technology2008，9，6： | 1 |
| 9 | Effect of dietary supplementation of chitosan and galacto-mannan-oligo- saecharides on serum parameters and the insulin-like growth factor-I mRNA expression in early weaned pig- lets显示文摘 | Tang Z R Yin Y L Nyachoti C M | 2005 | Domest Anim Endocrin2005，28，： | 1 |
| 10 | High - level expression of a manga- nese superoxide dismutase ( PoMn - SOD ) from Pleurotus ostreatus in Pichia pastoris 显示文摘 | Yin C Zhao W Zheng L | 2014 | Appl Biochem Biotechnol2014，174，1： | 1 |
| 11 | Fibrous hybrid of gra- phene and sulfur nanocrystals for high-performance lithium- sulfur batteries 显示文摘 | Zhou G G Yin L C Wang D W | 2013 | ACS Nano2013，7，6： | 1 |
| 12 | Luminescence properties of Dy3+-doped Li2Sr Si O4for NUV-excited white LEDs显示文摘 | You P L Yin G F Chen X C | 2011 | Opt Mater2011，33，11： | 1 |
| 13 | Polycyclic aromatic hydrocarbons in soils in the vicinity of Nanjing, China显示文摘 | Yin C Q Jiang X Yang X L | 2008 | Chemosphere2008，73，： | 1 |
| 14 | A planar U type monopole antenna for UWB applications 显示文摘 | YIN X C RUAN C L DING C Y | 2008 | Progress In Eleetromagnetics Research Letters2008，2，： | 1 |
| 15 | A hybrid model for selection of an outsourcing provider显示文摘 | James J H Liou H S Wang C C Hsu S L Yin | 2011 | Applied Mathematical Modelling2011，35，10： | 1 |
| 16 | A review on the development and commercialization of biomass gasification technologies in China显示文摘 | DENNIS Y C YIN X L WU C Z | 2004 | Renewable and Sustainable Energy Reviews2004，8，： | 1 |
| 17 | Approaching theoretical capacity of LiFePO4 at room temperature at high rates显示文摘 | Huang H Yin S C Nazra L F | 2001 | Electrochem Solid-State Lett2001，4，10： | 1 |
| 18 | Rest chest pain, negative treadmill exercise electrocardiogram and reverse redistribution in dipyridamole myocardial perfusion imaging might be the features of coronary artery spasm显示文摘 | XIANG D C YIN J L TENG A P | 2007 | Clin Cardiol2007，30，10： | 1 |
| 19 | Beneficial properties for insulin absorption using superporous hydrogel containing interpenetrating polymer network as oral delivery vehicles 显示文摘 | Yin L C Ding J Y Fei L K | 2008 | International Journal of Pharmaceutics2008，350，12： | 1 |
| 20 | Approaching theoreticalcapacity of LiFeP04 at room temperature at high rates 显示文摘 | HUANG H YIN S C NAZAR L F | 2001 | Electrochemical and Solid-State letters2001，4，10： | 1 |
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