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| 1 | 儿茶素抑制二甲基肼诱发小鼠大肠癌的实验研究显示文摘昆明种小鼠随机分成7组,1~5组小鼠皮下注射二甲基肼(1,2-Dimethylhydrazine,DMH),剂量20mg/kgbw,每周一次,连续20周。第2~5组于注射前一周开始灌胃儿茶素,每鼠每日分别为1mg、2mg、4mg、没食子酰表没食子儿茶素[(-)-Epigallo-catechingallate]2mg,第6组给儿茶素3mg作为对照组,每周连续5次至23周。第7组为溶剂对照组。27周处死小鼠,结果显示:两组对照组小鼠未发现肿瘤。DMH组大肠癌发生率为80%,与2~5组比较明显升高(P<0.001),结果提示:(1)不同剂量的儿茶素都具有防癌作用,其机理可能与诱导SOD等抗氧化剂的活性消除有害自由基有关;(2)其抑癌有效成分可能是多种儿茶素协同作用的结果;(3)儿茶素对个鼠无毒性作用。 | 银平章 祝庆蕃 程书钧 刘政国 孔令非 Y.Hara | 1994 | 营养学报1994，16，2： | 10 |
| 2 | 没食子酰表没食子儿茶素对促癌物TPA抑制作用的研究显示文摘本研究首次证明,绿茶多酚类的主要成分没食子酰表没食子儿茶素(EGCG)具有很强的抑制促癌物TPA诱导的皮肤炎性水肿和增生反应,以及抑制TPA促进经甲基胆蒽启动的BALB/3T3细胞的转化作用。本实验结果表明,EGCG可能是绿茶多酚提取物中抑制TPA促癌作用的重要成分。 | 童彤 程书钧 李秀琴 白谨峰 Y.Hara | 1992 | 癌变.畸变.突变1992，4，1： | 5 |
| 3 | 绿茶对实验性大肠癌抑制作用的研究显示文摘本实验观察了绿茶儿茶素对1,2-DMH诱发小鼠大肠癌的影响,结果显示:①绿茶多酚及绿茶水溶性提取物对1,2-DMH诱发C_57BL小鼠大肠隐窝上皮细胞徽核及凋谢有明显的拮抗作用。本实验所用微核及凋谢的测定方法是一种简便、快速而且经济的抗结肠致癌物筛选方法。②绿茶几茶素对大肠癌有预防作用,其抗癌机制可能与绿茶儿茶素成分中超氧化物歧化酶及其它抗氧化剂清除癌组织中自由基有关。 | 银平章 程书钧 赵进英 祝庆蕃 刘政国 孔令非 徐继跃 张广甫 党伟一 吴凯彦 Y.Hara | 1995 | 河南医学研究1995，4，2： | 3 |
| 4 | Non-Aligned Stagnation Point Flow of a Casson Fluid Past a Stretching Sheet in a Doubly Stratified Medium显示文摘This paper investigates the problem of oblique hydro magnetic stagnation point flow of an electrically conducting Casson fluid over stretching sheet embedded in a doubly stratified medium in the presence of thermal radiation and heat source/absorption with first order chemical reaction.It is assumed that the fluid impinges on the wall obliquely.Similarity variables were used to convert the partial differential equations to ordinary differential equations.The transformed ordinary differential equations are solved numerically using Runge-Kutta-Fehlberg method with shooting technique.It is observed that a boundary layer is formed when the stretching velocity of the surface is less than the in viscid free stream velocity at a point decreases with increase in the non-Newtonian rheology parameter.The augmentation of the temperature is observed with the magnetic parameter,heat source parameter and thermal radiation parameter while a reverse effect with thermal stratification number,Prandtl number and the velocity ratio parameter.Influence of Skin friction coefficient,Nusselt number and Sherwood number on the flow configurations for different values of pertinent parameters are portrayed graphically and discussed.Numerical results are compared with the published results and are found to be in good agreement with previously published results as special cases of present problem.The mass concentration is seen to be decrease with Schmidt number,chemical reaction parameter and solutal stratification number. | N.Vijaya G.Venkata Ramana Reddy Y.Hara Krishna | 2019 | Fluid Dynamics & Materials Processing2019，15，3： | 1 |
| 5 | Laboratory radiative accretion shocks on GEKKO XⅡlaser facility for POLAR project显示文摘A new target design is presented to model high-energy radiative accretion shocks in polars. In this paper, we present the experimental results obtained on the GEKKO XII laser facility for the POLAR project. The experimental results are compared with 2 D FCI2 simulations to characterize the dynamics and the structure of plasma flow before and after the collision. The good agreement between simulations and experimental data confirms the formation of a reverse shock where cooling losses start modifying the post-shock region. With the multi-material structure of the target,a hydrodynamic collimation is exhibited and a radiative structure coupled with the reverse shock is highlighted in both experimental data and simulations. The flexibility of the laser energy produced on GEKKO XII allowed us to produce high-velocity flows and study new and interesting radiation hydrodynamic regimes between those obtained on the LULI2000 and Orion laser facilities. | L.Van Box Som E.Falize M.Koenig Y.Sakawa B.Albertazzi E Barroso J.-M.Bonnet-Bidaud C.Busschaert A.Ciardi Y.Hara N.Katsuki R.Kumar E Lefevre C.Michaut Th.Michel T.Miura T.Morita M.Mouchet G.Rigon T.Sano S.Shiiba H.Shimogawara S.Tomiya | 2018 | High Power Laser Science and Engineering2018，6，2： | 0 |
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