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您的检索式：作者名="Xingfeng Yao"
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| 1 | Primary cardiac CIC-rearranged undifferentiated sarcoma in an infant显示文摘Introduction:Cardiac neoplasms are particularly rare in children,and the majority of these tumors are benign.Approximately 10%of cardiac neoplasms are malignant,including soft tissue sarcomas and lymphomas.Cardiac tumors could also be metastases.Primitive EWSR1-negative round or spindle cell undifferentiated sarcoma harboring CIC gene translocation is a highly aggressive malignancy mainly occurring in soft tissues.However,it has not yet been described in the heart.Case presentation:We report a sarcoma that arose from the right ventricle in a 1-year-old girl.Histologically,it was composed of closely arranged small round or oval undifferentiated cells with fibrovascular separation,hyaline degeneration,and geographical necrosis.Immunohistochemically,the neoplastic cells exhibited focal membrane positivity for CD99 and diffuse positivity for WT1 and ETV4.Fluorescent in situ hybridization analysis showed EWSR1-negative but CIC-positive split signals.The breakpoint was also confirmed by whole genome sequencing.Conclusion:Based on morphological,immunohistochemical and molecular findings,this cardiac mass was diagnosed as CIC-rearranged sarcoma. | Meng Zhang Yeran Yang Xiaoxing Guan Xingfeng Yao Yongli Guo Lejian He | 2021 | Pediatric Investigation2021，5，4： | 0 |
| 2 | Functional and phylogenetic structures of pheasants in China显示文摘Biodiversity has been subjected to increasing anthropogenic pressures.It is critical to understand the different processes that govern community assembly and species coexistence under biogeographic processes and anthropogenic events.Pheasants(Aves:Phasianidae)are highly threatened birds and China supports the richest pheasant species worldwide.Unravelling the spatial patterns and underlying factors associated with multidimensional biodiversity of species richness(SR),functional diversity(FD),and phylogenetic diversity(PD)of pheasants in China is helpful to understand not only the processes that govern pheasant community assembly and species coexistence,but also pheasant biodiversity conservation.We used a total of 45 pheasant species in China and analyzed the SR,FD,PD,and functional and phylogenetic structures by integrating species distribution maps,functional traits and phylogenies based on 50 km×50 km grid cells.We further used simultaneous autoregressive(SAR)models to explore the factors that determined these patterns.The southern Qinghai-Tibetan Plateau(QTP),Hengduan Mountains,southwestern Mountains,the east of the Qilian Mountains,the Qinling,southern China displayed higher SR,FD,and PD,which were determined by elevation,habitat heterogeneity,temperature seasonality,and vegetation cover.Elevation primarily determined the functional and phylogenetic structures of the pheasant communities.Assemblages in the highlands were marked by functional and phylogenetic clustering,particularly in the QTP,whereas the lowlands in eastern China comprised community overdispersion.Clustered pheasant assemblages were composed of young lineages.Patterns of functional and phylogenetic structures and richness-controlled functional and phylogenetic diversity differed between regions,suggesting that phylogenetic structures are not a good proxy for identifying functional structures.We revealed the significant role of elevation in pheasant community assemblages in China.Highlands interacted with community clustering,whereas lowlands interacted with overdispersion,supporting the environmental filtering hypothesis.Biogeographical drivers other than anthropogenic factor determined biodiversity of pheasants at the present scale of China.This study provides complementary background resources for multi-dimensional pheasant biodiversity and provides insights into avian biodiversity patterns in China. | Hongyan Yao Pengcheng Wang Nan Wang Philip J.K.McGowan Xingfeng Si Jianqiang Li Jiliang Xu | 2022 | Avian Research2022，13，3： | 0 |
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