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| 1 | Optical vortices 30 years on:OAM manipulation from topological charge to multiple singularities显示文摘Thirty years ago,Coullet et al.proposed that a special optical field exists in laser cavities bearing some analogy with the superfluid vortex.Since then,optical vortices have been widely studied,inspired by the hydrodynamics sharing similar mathematics.Akin to a fluid vortex with a central flow singularity,an optical vortex beam has a phase singularity with a certain topological charge,giving rise to a hollow intensity distribution.Such a beam with helical phase fronts and orbital angular momentum reveals a subtle connection between macroscopic physical optics and microscopic quantum optics.These amazing properties provide a new understanding of a wide range of optical and physical phenomena,including twisting photons,spin–orbital interactions,Bose-Einstein condensates,etc.,while the associated technologies for manipulating optical vortices have become increasingly tunable and flexible.Hitherto,owing to these salient properties and optical manipulation technologies,tunable vortex beams have engendered tremendous advanced applications such as optical tweezers,high-order quantum entanglement,and nonlinear optics.This article reviews the recent progress in tunable vortex technologies along with their advanced applications. | Yijie Shen Xuejiao Wang Zhenwei Xie Changjun Min Xing Fu Qiang Liu Mali Gong Xiaocong Yuan | 2019 | Light(Science & Applications)2019，8，1： | 77 |
| 2 | clusterProfiler 4.0:A universal enrichment tool for interpreting omics data显示文摘Functional enrichment analysis is pivotal for interpreting highthroughput omics data in life science.It is crucial for this type of tool to use the latest annotation databases for as many organisms as possible.To meet these requirements,we present here an updated version of our popular Bioconductor package,clusterProfiler 4.0.This package has been enhanced considerably compared with its original version published 9 years ago.The new version provides a universal interface for functional enrichment analysis in thousands of organisms based on internally supported ontologies and pathways as well as annotation data provided by users or derived from online databases.It also extends the dplyr and ggplot2 packages to offer tidy interfaces for data operation and visualization.Other new features include gene set enrichment analysis and comparison of enrichment results from multiple gene lists.We anticipate that clusterProfiler 4.0 will be applied to a wide range of scenarios across diverse organisms. | Tianzhi Wu Erqiang Hu Shuangbin Xu Meijun Chen Pingfan Guo Zehan Dai Tingze Feng Lang Zhou Wenli Tang Li Zhan Xiaocong Fu Shanshan Liu Xiaochen Bo Guangchuang Yu | 2021 | The Innovation2021，2，3： | 40 |
| 3 | On-chip plasmonic spin-Hall nanograting for simultaneously detecting phase and polarization singularities显示文摘Phase and polarization singularities are important degrees of freedom for electromagnetic field manipulation.Detecting these singularities is essential for modern optics,but it is still a challenge,especially in integrated optical systems.In this paper,we propose an on-chip plasmonic spin-Hall nanograting structure that simultaneously detects both the polarization and phase singularities of the incident cylindrical vortex vector beam(CVVB).The nanograting is symmetry-breaking with different periods for the upper and lower parts,which enables the unidirectional excitation of the surface plasmon polariton depending on the topological charge of the incident optical vortex beam.Additionally,spin-Hall meta-slits are integrated onto the grating so that the structure has a chiral response for polarization detection.We demonstrate theoretically and experimentally that the designed structure fully discriminates both the topological charges and polarization states of the incident beam simultaneously.The proposed structure has great potential in compact integrated photonic circuits. | Fu Feng Guangyuan Si Changjun Min Xiaocong Yuan Michael Somekh | 2020 | Light(Science & Applications)2020，9，1： | 11 |
| 4 | Versatile on-chip light coupling and(de)multiplexing from arbitrary polarizations to controlled waveguide modes using an integrated dielectric metasurface显示文摘Metasurfaces have found broad applicability in free-space optics,while its potential to tailor guided waves remains barely explored.By synergizing the Jones matrix model with generalized Snell’s law under the phase-matching condition,we propose a universal design strategy for versatile on-chip mode-selective coupling with polarization sensitivity,multiple working wavelengths,and high efficiency concurrently.The coupling direction,operation frequency,and excited mode type can be designed at will for arbitrary incident polarizations,outperforming previous technology that only works for specific polarizations and lacks versatile mode controllability.Here,using silicon-nanoantenna-patterned silicon-nitride photonic waveguides,we numerically demonstrate a set of chip-scale optical couplers around 1.55μm,including mode-selective directional couplers with high coupling efficiency over 57%and directivity about 23 d B.Polarization and wavelength demultiplexer scenarios are also proposed with 67%maximum efficiency and an extinction ratio of 20 d B.Moreover,a chip-integrated twisted light generator,coupling free-space linear polarization into an optical vortex carrying 1 h orbital angular momentum(OAM),is also reported to validate the mode-control flexibility.This comprehensive method may motivate compact wavelength/polarization(de)multiplexers,multifunctional mode converters,on-chip OAM generators for photonic integrated circuits,and high-speed optical telecommunications. | YUAN MENG ZHOUTIAN LIU ZHENWEI XIE RIDE WANG TIANCHENG QI FUTAI HU HYUNSEOK KIM QIRONG XIAO XING FU QIANG WU SANG-HOON BAE MALI GONG XIAOCONG YUAN | 2020 | Photonics Research2020，8，4： | 8 |
| 5 | VPS4B mutation impairs the osteogenic differentiation of dental follicle cells derived from a patient with dentin dysplasia type I显示文摘A splicing mutation in VPS4B can cause dentin dysplasia type I(DD-I),a hereditary autosomal-dominant disorder characterized by rootless teeth,the etiology of which is genetically heterogeneous.In our study,dental follicle cells(DFCs)were isolated and cultured from a patient with DD-I and compared with those from an age-matched,healthy control.In a previous study,this DD-I patient was confirmed to have a loss-of-function splicing mutation in VPS4B(IVS7+46C>G).The results from this study showed that the isolated DFCs were vimentin-positive and CK14-negative,indicating that the isolated cells were derived from the mesenchyme.DFCs harboring the VPS4B mutation had a significantly higher proliferation rate from day 3 to day 8 than control DFCs,indicating that VPS4B is involved in cell proliferation.The cells were then replenished with osteogenic medium to investigate how the VPS4B mutation affected osteogenic differentiation.Induction of osteogenesis,detected by alizarin red and alkaline phosphatase staining in vitro,was decreased in the DFCs from the DD-I patient compared to the control DFCs.Furthermore,we also found that the VPS4B mutation in the DD-I patient downregulated the expression of osteoblast-related genes,such as ALP,BSP,OCN,RUNX2,and their encoded proteins.These outcomes confirmed that the DD-I-associated VPS4B mutation could decrease the capacity of DFCs to differentiate during the mineralization process and may also impair physiological root formation and bone remodeling.This might provide valuable insights and implications for exploring the pathological mechanisms underlying DD-I root development. | Qiang Li Fangli Lu Tianxuan Chen Ke Zhang Yuping Lu Xiaocong Li Yingying Wang Ling Liu Qing Tian Fu Xiong Dong Chen | 2020 | International Journal of Oral Science2020，12，3： | 2 |
| 6 | Research advances in genetic engineering of plantibody显示文摘The combination of engineering antibody and plant biotechnology creates the plantibody. It has been reported that the engineering antibodies expressed in plant, no matter whether they are intact or small-molecular antibodies, keep their antigen-binding specificity, which means they are functional.This trait makes plantibody notable. Now the researches are focused mainly on the following three aspects: ( ⅰ ) Therapeutic antibody in clinic. It is expected to offer the opportunity of large-scale antibody production in agriculture systems, for the purpose of decreasing the cost greatly. Moreover, the property of multiple sexual hybridization between plants can be used to produce bi-or multi-functional antibodies and create new antibody medicines. (ⅱ) Plant physiology. Engineering antibodies against plant hormones or some active materials can block their activities in plant, so the trait of plantibody could be used to study the growth and development of plant. ( ⅲ ) Plant disease-resistance. The gene of | Junzhi Zeng Yu Fu Xiaocong Yu Xin Jiang Hualiang Huang | 1999 | Chinese Science Bulletin1999，44，5： | 0 |
| 7 | SOLAR RADIO OBSERVATIONS DURING SOLAR-TERRESTRIAL JOINT-OBSERVATIONS IN MARCH AND AUGUST 1989显示文摘1.The renewing project has been finished in the middle of 1989. A new radio telescope at 10.6 cm-λ has started to work since 16 June,1989.Itscomputer data acquision system for two channels of 1 sec and 1 msec has come to oper-ate in Feburary,1990. | Fu Qijun, Liu Yuying, Li Xiaocong, Wang Shulan, Chen Zhijun, Zhao Bing, Zhai PujiangBeijing Astronomical Observatory, Chinese Academy of Chinese, Beijing 100080, China | 1990 | 天文研究与技术1990，，4： | 0 |
| 8 | On-chip sorting of orbital angular momentum beams using Bloch surface wave structures显示文摘Owing to their unique optical properties and new degrees of freedom,orbital angular momentum(OAM)beams have been applied in various fields.Detection of the topological charges(TCs)of OAM beams is the key step for their applications.However,on-chip sorting of OAM beams with large TCs still remains a challenge.In this paper,Bloch surface wave(BSW)structures with five semi-ring shaped nanoslits are modeled.A spatial separation of 135 nm on the chip is obtained between two neighboring OAM states.OAM beams with TCs up to 35 can be successfully sorted by the BSW structures,which is much larger than that using metallic structures(only seven).BSW structures exhibit better OAM sorting performances than metallic structures.We systematically show how the lower attenuation of BSW structures leads to far superior separation ability compared to surface plasmons propagating on metallic structures.In addition,sorting of two OAM beams with different TCs simultaneously can be achieved in this way.Our results reveal that BSW structures should be an excellent solution for OAM sorting with large TCs,which is beneficial for applications in integrated on-chip devices and optical communications. | NANNAN LI QI ZOU YIZHI LAN YAQI WANG JUN ZHANG MICHAEL SOMEKH CHANGJUN MIN FU FENG XIAOCONG YUAN | 2023 | Photonics Research2023，11，11： | 0 |
| 9 | Exploitation of geometric and propagation phases for spin-dependent rational-multiple complete phase modulation using dielectric metasurfaces显示文摘Metasurfaces have drawn considerable attention in manipulation of electromagnetic waves due to their exotic subwavelength footprints. Regardless of immense progress of polarization-dependent flat optics, the realization of on-device switchable complete phase multiplication is still missing from design multifunctional devices. Here,by combining geometric and propagation phases, a generalized design principle is proposed that can achieve switchable integer or fractional multiple complete phase modulation in transmitted circularly cross-polarized light by switching the handedness of incident polarization. As a proof of concept, two types of spin-dependent bifunctional wavefront manipulating devices, including switchable beam splitter/beam deflector and spinto-orbital angular momentum converter designs are numerically realized. It is believed that the proposed single-cell spin-switchable rational-multiple complete-phase-modulation design principle based on combined propagation and geometric phases has great potential to underpin the development of meta-optics-based multifunctional operations in the field of integrated optics, imaging, and optical communication. | Ata Ur Rahman Khalid Fu FENG Naeem Ullah Xiaocong Yuan Michael Geoffrey Somekh | 2022 | Photonics Research2022，10，4： | 0 |
| 10 | A new member of the structured light family:optical spatiotemporal vortices显示文摘The burgeoning growth of structured light has opened up new possibilities for harnessing the spatiotemporal coupling effects in light.Optical spatiotemporal vortices,as a subset of spatiotemporal light,have emerged as a focal point of recent research,owing to their distinctive characteristics and vast range for application.This unique structured light will endow photons with a new degree of freedom,promising to revolutionize researchers’understanding of photonics.Conducting thorough research on optical spatiotemporal vortices will establish a solid foundation for the development of innovative physical mechanisms and advanced applications in photonics. | Fu Feng Xiaocong Yuan | 2023 | Light(Science & Applications)2023，12，10： | 0 |
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