|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | 脂质组学改善传统危险因素预测的2型糖尿病患者的心血管事件显示文摘临床脂质测定并未显示出糖尿病或心血管病相关的脂质代谢改变的复杂性。脂质组学则能够评估可作为疾病风险潜在标志物的数百种脂质种类。方法:纳入来自糖尿病治疗和血管保护行动。 | 刘莉 叶鹏 Alshehry ZH Mundra PA Barlow CK Mellett NA Wong G McConville MJ Simes J Tonkin AM Sullivan DR Barnes EH Nestel PJ Kingwell BA Marre M Neal B Poulter NR Rodgers A Williams B Zoungas S Hillis GS Chalmers J Woodward M Meikle PJ | 2016 | 中华高血压杂志2016，24，10： | 3 |
| 2 | Confocal microscopic analysis reveals sprouting of primary afferent fibres in rat dorsal horn after spinal cord injury显示文摘 | Wong ST Atkinson BA Weaver LC | 2000 | Neurosci Lett2000，296，23： | 1 |
| 3 | Inhalation exposure systems:design,methods and operation显示文摘 | Wong BA | 2007 | Toxicol Pathol2007，35，1： | 1 |
| 4 | SOCS-3 nega- tively regulates innate and adaptive immune mecha- nisms in acute IL-l-dependent inflammatory arthritis显示文摘 | Wong PK Egan PJ Croker BA | 2006 | J Clin Invest2006，116，6： | 1 |
| 5 | Oral subchronic and genotoxicity studies conducted with the amino acid,L-glutamine显示文摘 | Wong AW Magnuson BA Nakagawa K | 2011 | Food Chem Toxicol2011，49，9： | 1 |
| 6 | Plasma-mediated radiofrequency ablation assisted percutaneous cement injection for treating advanced malig- nant vertebral compression fractures显示文摘 | Georgy BA Wong W | 2007 | AJNR Am J Neuroradiol2007，28，4： | 1 |
| 7 | Functional effects of cancer mitochondria on energy metabolism and tumorigenesis:utility of transmitochondrial cybrids显示文摘 | Kaipparettu BA Ma Y Wong LJ | 2010 | Ann N Y Acad Sci2010，1201，1： | 1 |
| 8 | Multifunctional oxygen-enriching nano-theranostics for cancer-specific magnetic resonance imaging and enhanced photodynamic/photothermal therapy显示文摘The combination of photodynamic therapy(PDT)and photothermal therapy(PTT)has attracted much interest in recent years,but non-specific distribution of photosensitizers and intrinsic tumor hypoxic microenvironment have continued to limit its therapeutic efficiency.We herein report a nano-theranostic system,denoted as Ce6-CuS/MSN@PDA@MnO2-FA NPs,which combines PDT,PTT,magnetic resonance(MR)imaging with hypoxia-relieving and tumor-targeting functionalities.Central to this design is the use of mussel-inspired polydopamine(PDA)coating to encapsulate the chlorin e6(Ce6)and copper sulfide nanoparticles(CuS NPs)loaded mesoporous silica nanoparticle(MSN)core.The PDA coating not only acts as pH sensitive gatekeeper to prevent the premature release of Ce6 under non-acidic tumor microenvironment(TME),but also facilitates post-functionalization so that hypoxia-relieving MnO2 nano-sheets and tumor-targeting ligand folic acid-PEG-thiol(FA-PEG-SH)can be decorated on the outer part of the drug system.In vitro and in vivo measurements clearly demonstrated that all these functionalities worked synergistically as expected.The system,having a low dark cytotoxicity,can be effectively internalized by 4T1 cells and decrease the cell viability to 2%upon 660 nm/808 nm laser irradiation.Tumors in 4T1 tumor-bearing mice can almost be completely destroyed in 2 weeks via combined PDT/PTT.Together with the TME-sensitive MR imaging performance demonstrated,Ce6-CuS/MSN@PDA@MnO2-FA NPs represent a multifunctional prototype which holds great potential to be developed into clinical theranostics. | Li Zhang Zhe Yang Jinghua Ren Li Ba Wenshan He Chun-Yuen Wong | 2020 | Nano Research2020，13，5： | 1 |
| 9 | Effects of benzene on spleniethymic, and femoral lymphcytes in mice显示文摘 | Farris GM Robinson SN Wong BA | 1997 | Toxicology1997，118，23： | 1 |
| 10 | Irreversible electroporation in eradication of rabbit VX2 liver tumor显示文摘 | Lee EW Wong D Tafti BA | 2012 | J Vasc Interv Radiol2012，23，6： | 1 |
| 11 | Two trocar laparoscopic varicocelectomy : Approach and outcomes 显示文摘 | Link BA Kruska JD Wong C | 2006 | JSLS2006，10，2： | 1 |
| 12 | Pulmonary responses of mice, rats, and hamsters to subchronic inhalation of ultrafine titanium dioxide particles 显示文摘 | Bermudez E Mangum JB Wong BA Asgharian B Hext PM David B Everitt J | 2004 | Toxicol Sci2004，77，2： | 1 |
| 13 | SOCS--3 negatively reg- ulates innate and adaptive immune mechanisms in acute IL-l-dependent inflammatory arthritis 显示文摘 | Wong PK Egan PJ Croker BA | 2006 | J Clin Invest2006，116，6： | 1 |
| 14 | Interhospital transfer delays appropriate treatment for patients with severe sepsis and septic shock:a retrospective cohort study显示文摘 | Faine BA Noack JM Wong T | 2015 | Crit Care Med2015，43，12： | 1 |
| 15 | Plasma-mediated radiofrequency abation assisted percutaneous cement injection for treating advanced malignant vertebral compression fractures 显示文摘 | Georgy BA Wong W | 2007 | AJNR Am J Neuroradiol2007，28，4： | 1 |
| 16 | Basal ganglia neurotransmitter concentrations in rhesus monkeys following subchronic manganese sulfate inhalation显示文摘 | Struve MF McManus BE Wong BA | 2007 | Am J Ind Med2007，50，： | 1 |
| 17 | Opposites attract: a case of magnet ingestion显示文摘 | WONG HH PHILLIPS BA | 2009 | CJEM2009，11，5： | 1 |
| 18 | Pulmonary response of mice,rats,and hamsters to subchronic inhalation of ultrafine titanium dioxide particles显示文摘 | Bermudez E Mangum JB Wong BA | 2004 | Toxicol Sci2004，77，2： | 1 |
| 19 | Pulmonary responses of mice, rats and hamsters to sub-chronic inhalation of uhrafine titanium dixoide partials 显示文摘 | Bermudez E Mangum JB Wong BA | 2004 | Toxicol Sci2004，77，4： | 1 |
| 20 | Irreversible electroporation in eradication of rabbit VX2 liver tumor显示文摘 | Lee EW Wong D Tafti BA | 2012 | J Vasc Interv Radiol2012，23，6： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员