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| 1 | Magnetic control of electrocatalyticand bioelectrocatalytic processes显示文摘 | Itamar Willner Eugenil Katz | 2003 | Angewandte ChemieInternational Edition2003，42，45： | 1 |
| 2 | Biomolecule-functionalizd carbon显示文摘 | Eugenii Kate Itamar Willner | 2004 | Nanotubes Chem Phys Chem2004，5，： | 1 |
| 3 | Functional DNA Structures and Their Biomedical Applications显示文摘Since the discovery of the double-helix structure in 1953,nucleic acids have been developed from natural genetic codes into functional building blocks in a wide range of biotechnology and materials sciences.Taking advantage of their design diversity and biocompatibility,functional nucleic acids facilitate the“bottom-up”fabrication of nanomaterials that are highly potential for molecular medicine to treat different diseases,such as cancers.The present perspective article introduces recent advances in the use of these unique properties of nucleic acid biopolymers for biomedical applications.Specifically,nanomaterial/nucleic acid hybrid structures for sensing,controlled drug release,programmable intracellular imaging,and apoptosis,as well as logic calculation,are discussed.Furthermore,the detailed operation for both extracellular and intracellular bioactivity regulation with these new design functional nucleic acid nanostructures are fully illustrated. | Ziyuan Li Chen Wang Jiang Li Junji Zhang Chunhai Fan Itamar Willner He Tian | 2020 | CCS Chemistry2020，2，5： | 1 |
| 4 | Amplified surface plasmon resonance and electrochemical detection of Pb(2+) ions using the Pb(2+)-dependent DNAzyme and Hemin/G-Quadruplex as a label显示文摘 | Pelossof Gilad Tel-Vered Ran Willner Itamar | 2012 | Analytical Chem2012，84，8： | 1 |
| 5 | Amplified surface plasmon resonance and electrochemical detection of Pb(2+) ions using the Pb(2+)-dependent DNAzyme and Hemin/G-quadruplex as a label显示文摘 | Pelossof Gilad Tel-Vered Ran Willner Itamar | 2012 | Analytical Chemistry2012，84，8： | 1 |
| 6 | Electroswitchable photoelectrochemistry by Cu2+-polyacrylic Acid/CdS-nanoparticle assemblies显示文摘 | Laila Sheeney-Haj-Ichia Zoya Cheglakov Itamar Willner | 2004 | J Phys Chem B2004，108，： | 1 |
| 7 | Enhanced photoelectrochemistry in supramolecular CdS-nanoparticle-stoppered pseudorotaxane monolayers assembled on electrodes显示文摘 | Laila Sheeney Haj Ichia Itamar Willner | 2002 | J Phys Chem B2002，106，13： | 1 |
| 8 | Biomaterials for sensors, fuel cells, and circuitry显示文摘 | Itamar Willner | 2002 | Science2002，298，： | 1 |
| 9 | Construction of a Homogeneous Enzyme-Free Autocatalytic Nucleic Acid Machinery for High-Performance Intracellular Imaging of MicroRNA显示文摘Enzyme-free autocatalytic nucleic acidmachinery has been widely used to engineer various self-assembled nanostructures as well as high-performance bioanalysis,yet has rarely been realized in live cells for complicated design,low robustness,and limited reliability.Herein,we constructed simple yet versatile enthalpy-driven autocatalytic hybridization chain reaction(AHCR)machinery with high reliability and robustness for in situ microRNA analysis in live cells.The homogeneous AHCR machine was composed of two differently designed HCR modules,the lead-in HCR-1 amplification module,and the reverse HCR-2 feedback module.After the AHCR amplification system was delivered into live cells,target microRNA stimulated the autonomous cross-invasion of the HCR-1 module and the HCR-2 module for assembling hyperbranched dsDNA nanostructures with synergistically amplified Förster resonance energy transfer readout,thus enabling accurate intracellular micro-RNA imaging.The synergistic AHCR execution was systematically investigated by a series of experimental studies and computer-aided theoretical simulations.The multiple recognition capacity of HCR constituents and the successive signal amplification of the AHCR machine enabled the accurate intracellular microRNA imaging with precise signal localization inside living cells.Based on its intriguing and modular design,the AHCR machinery can be extended for analyzing diverse biomarkers,thus supplementing a powerful toolbox for clinical diagnosis and therapeutic assessment. | Jie Wei Jinhua Shang Shizhen He Yu Ouyang Itamar Willner Fuan Wang | 2022 | CCS Chemistry2022，4，11： | 0 |
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