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| 1 | Cyclooxygenase-2 and epithelial growth factor receptor up-regulation during progression of Barrett's esophagus to adenocarcinoma显示文摘瞄准:在整个 Barretts 食管的前进调查 cyclooxygenase-2 (COX-2 ) 和上皮的生长因素受体(EGFR ) 的表示() 。方法:COX-2 和 EGFR 蛋白质表情被使用免疫检测组织化学的方法。详细 cytomorphological 改变的 A 是坚定的。COX-2 和 EGFR 表示的区域被使用计算机成像系统确定。结果:COX-2 和 EGFR 的表情与前进一起增加了从到食管腺癌(EAC ) 。积极关联在 COX-2 表示和 EGFR 表示之间被发现。结论:COX-2 和 EGFR 可能在逐步的前进从是合作的到 EAC,从而导致致癌作用。 | Yan Li John M Wo Mukunda B Ray Whitney Jones Ruifeng R Su Susan Ellis Robert C G Martin | 2006 | World Journal of Gastroenterology2006，12，6： | 14 |
| 2 | Operative complications and economic outcomes of cholecystectomy for acute cholecystitis显示文摘BACKGROUND Recent management of acute cholecystitis favors same admission(SA)or emergent cholecystectomy based on overall shorter hospital stay and therefore cost savings.We adopted the practice of SA cholecystectomy for the treatment of acute cholecystitis at our tertiary care center and wanted to evaluate the economic benefit of this practice.We hypothesized that the existence of complications,particularly among patients with a higher degree of disease severity,during SA cholecystectomy could negate the cost savings.AIM To compare complication rates and hospital costs between SA vs delayed cholecystectomy among patients admitted emergently for acute cholecystitis.METHODS Under an IRB-approved protocol,complications and charges for were obtained for SA,later after conservative management(Delayed),or elective cholecystectomies over an 8.5-year period.Patients were identified using the acute care surgery registry and billing database.Data was retrieved via EMR,operative logs,and Revenue Cycle Operations.The severity of acute cholecystitis was graded according to the Tokyo Guidelines.TG18 categorizes acute cholecystitis by Grades 1,2,and 3 representing mild,moderate,and severe,respectively.Comparisons were analyzed withχ2,Fisher’s exact test,ANOVA,ttests,and logistic regression;significance was set at P<0.05.RESULTS Four hundred eighty-six(87.7%)underwent a SA while 68 patients(12.3%)received Delayed cholecystectomy.Complication rates were increased after SA compared to Delayed cholecystectomy(18.5%vs 4.4%,P=0.004).The complication rates of patients undergoing delayed cholecystectomy was similar to the rate for elective cholecystectomy(7.4%,P=0.35).Mortality rates were 0.6%vs 0%for SA vs Delayed.Patients with moderate disease(Tokyo 2)suffered more complications among SA while none who were delayed experienced a complication(16.1%vs 0.0%,P<0.001).Total hospital charges for SA cholecystectomy were increased compared to a Delayed approach($44500±$59000 vs$35300±$16700,P=0.019).The relative risk of developing a complication was 4.2x[95%confidence interval(CI):1.4-12.9]in the SA vs Delayed groups.Among eight patients(95%CI:5.0-12.3)with acute cholecystitis undergoing SA cholecystectomy,one patient will suffer a complication.CONCLUSION Patients with Tokyo Grade 2 acute cholecystitis had more complications and increased hospital charges when undergoing SA cholecystectomy.This data supports a selective approach to SA cholecystectomy for acute cholecystitis. | Christopher P Rice Krishnamurthy B Vaishnavi Celia Chao Daniel Jupiter August B Schaeffer Whitney R Jenson Lance W Griffin William J Mileski | 2019 | World Journal of Gastroenterology2019，25，48： | 8 |
| 3 | Invasive Pneumococcal Disease in Children 5 Years After Conjugate Vaccine Introduction - Eight States, 1998-2005显示文摘 | Reingold A Hadler J Farley M M Harrison L Lynfield R Lexau C Bennett N Thomas A Craig A S Smith P J Beall B Whitney C G Moore M Pilishvili T | 2008 | MMWR Morbidity and Mortality Weekly Report2008，，6： | 1 |
| 4 | Serum immunoglobulin G antibody to Porphyromonas gingivalis in rapidly progressive periodontitis:titer,avidity,and subclass distribution显示文摘 | Whitney C Ant J Monela B | 1992 | Infect Immun1992，60，6： | 1 |
| 5 | Microsatellites for next-generation ecologists:a post-sequencingbioinformatics pipeline显示文摘 | Femandez-Silva I Whitney J Wainwright B | 2013 | PLoS one2013，8，55： | 1 |
| 6 | Reinforcedconcrete folded plate construction 显示文摘 | Whitney C S Anderson B G Birnbaum H | 1959 | Journal of theStructural Division ASCE1959，85，8： | 1 |
| 7 | Isolation of a candidate gene for Menkes disease and evidence that it encodes a copper - transporting ATPase 显示文摘 | Vulpe C Levinson B Whitney S | 1993 | Nat Genet1993，3，1： | 1 |
| 8 | Overlapping synthet- ic peptides encoding TPD52 as breast cancer vaccine in mice:pro- longed survival显示文摘 | Mirshahidi S Kramer V G Whitney J B | 2009 | Vaccine2009，27，12： | 1 |
| 9 | On a test of whether one of two random variables is stochastically larger than the other 显示文摘 | Mann H B Whitney D R | 1947 | An- nals of Mathematical Statistics1947，18，： | 1 |
| 10 | Optical sensor based field element size and sensing strategy for nitrogen application显示文摘 | Solie J B Raun W R Whitney R W | 1996 | Trans ASAE1996，39，6： | 1 |
| 11 | Abbreviations for namesof rock - forming minerals 显示文摘 | WHITNEY D L EVANS B W | 2010 | American Mineralogist2010，95，： | 1 |
| 12 | Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stageⅡB2ⅣA carcinoma of the cervix with negative para2aortic lymph nodes:a Gynecologic Oncology Group and Southwest Oncology Group study显示文摘 | Whitney C W Sause W Bundy B N | 1999 | J Clin Oncol1999，17，5： | 1 |
| 13 | A random- ized comparison of fluorouracil plus cisplafin versus hydroxyurea as an adjunct to radiation therapy in stages ⅡB-ⅣA carcinoma of the cervix with negative para-aortic lymph nodes: A Gynecologic Oncology Group and South- west Oncology Group study显示文摘 | Whitney C W Sause W Bundy B N | 1999 | J Clin Oncol1999，17，5： | 1 |
| 14 | A field investigation to examine the effects of the sprayer type, ground speed, and volume rate on spray deposition in Florida citrus 显示文摘 | Whitney J D Salyani M Churchill D B | 1989 | Journal of Agricultural Engineering Research1989，，42： | 1 |
| 15 | Randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stage Ⅱ B-ⅣA carcinoma of the cervix with negative para-aortic lymph nodes: a Gynecologic Oncology Group and Southwest Oncology Group study 显示文摘 | Whitney C W Sause W Bundy B N | 1999 | J Clin Oncol1999，17，5： | 1 |
| 16 | Optical sensor based field element size and sensing strategy for nitrogenapplication 显示文摘 | Solie J B Raun W R Whitney R W | 1996 | Trans ASAE1996，39，6： | 1 |
| 17 | In vivo fluorescence imaging of atherosclerotic plaques with ac- tivatahle cell-penetrating peptides targeting thrombin activity显示文摘 | Olson ES Whitney MA Friedman B | 2012 | Integr Biol (Camb)2012，4，： | 1 |
| 18 | Correlation of mannitol fermentation with virulence-associated genotypic characteristics in Vibrio vulnificus isolates from oysters and water samples in the Gulf of Mexico 显示文摘 | Drake SL Whitney B Levine JF | 2010 | Foodborne Pathog Dis2010，7，1： | 1 |
| 19 | Lightning location and storm severity display system 显示文摘 | Whitney B F Asgeirsson H | 1991 | IEEE Trans on Power Delivery1991，6，4： | 1 |
| 20 | Analysis for vinyl chloride in PVC powders by head-space gas chromatography显示文摘 | BERENS A R CRIDER L B TOMANEK C J WHITNEY J M | 2003 | J Appl Poly Sci2003，19，12： | 1 |
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