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| 1 | Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombininduced barrier breakdown显示文摘 | Baumer Y Spindler V Werthmann RC | | 0，，03： | 1 |
| 2 | A step-by-step description of a computationally efficient version of multiple hypothesis tracking 显示文摘 | Werthmann J R | 1992 | SPIE1992，1698，： | 1 |
| 3 | 查看详情显示文摘 | Weidner S Kuehn G Werthmann B Schroeder H. Just U. Borowski R. Decker R. Schwarz B. Schmuecking I.and Seifert | | 0，，： | 1 |
| 4 | A step-by-step description of a computationally efficient version of multiple hypothesis tracking显示文摘 | Werthmann J R | 1992 | SPIE Signal and Data Processing of Small Targets1992，1698，： | 1 |
| 5 | An antagonistic IL-4 mutant prevents type Ⅰ allergy in the mouse: inhibition of the IL-4/IL-13 receptor system completely abrogates humoral immune response to allergen and development of allergic symptoms in vivo显示文摘 | Grunewald SM Werthmann A Schnarr B | 1998 | J Immunol1998，160，8： | 1 |
| 6 | Muscle weak ness and early stages of liver failure in a 22-year old man 显示文摘 | Scheicht D Werthmann ML Zeglam S | 2013 | Internist (Berl)2013，54，8： | 1 |
| 7 | Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombin-induced barrier breakdown 显示文摘 | Baumer Y Spindler V Werthmann RC | 2009 | J Cell Physiol2009，220，3： | 1 |
| 8 | Durable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts-A case report 显示文摘 | Werthmann P C~ Str~lter ~ Friesland H | 2013 | Phytomedicine2013，20，3： | 1 |
| 9 | An antagonistic IL4 mutant prevents type Ⅰ allergy in the mouse: inhibition of the IL4/IL-13 receptor system completely abrogates humoral immune response to allergen and development of allergic symptoms in vivo显示文摘 | Grunewald SM Werthmann A | 1998 | J Immunol1998，160，8： | 1 |
| 10 | A step-by-step description of a computationally efficient version of multiple hypothesis tracking 显示文摘 | J R Werthmann | 1992 | SPIE Signal and Data Processing of Small Targets1992，1698，： | 1 |
| 11 | Study a- bout Hard Particles in Fluting Papers in Relation to Abra- sion of Corrugator Roll 显示文摘 | WERTHMANN B HUNGER J GRIEBENOW W | 1979 | Wochenblatt Fur Papier Fabri- cation1979，，4： | 1 |
| 12 | Study about Hard Particles in Fluting Papers in Relation to Abra- sion of Corrugator Roll显示文摘 | WERTHMANN B HUNGER J GRIEBENOW W | 1979 | Wochenblatt Fur Papier Fabrica- tion1979，，4： | 1 |
| 13 | Durable response of cutaneous squamous cell carcinoma following high-dose peri-lesional injections of Viscum album extracts-A case report显示文摘 | Werthmann P G Str/iter G Friesland H | 2013 | Phytomedicine2013，20，3： | 1 |
| 14 | Long-term survival of a patient with advanced pancreatic cancer under adjunct treatment with Viscum album extracts: A case report显示文摘BACKGROUND Advanced pancreatic cancer(aPC) has a poor prognosis with limited survival benefit from current standard treatment. Viscum album extracts(VAE) are used by many cancer patients, showing immune-stimulating effects, improved quality of life, and a survival benefit in patients with aPC.CASE SUMMARY A 59-year-old architect developed epigastric pain. A cystic lesion of the pancreas of 45-mm diameter was detected. In a follow-up magnetic resonance imaging,about one year later, multiple lesions were seen in the corpus and the tail of the pancreas; CA-19-9 was elevated to 58.5 U/mL. A distal pancreatectomy with splenectomy was performed, and a tumor of 7 cm × 5 cm × 3.5 cm was excised.Histologic investigation showed an intraductal papillary mucinous neoplasmassociated invasive adenocarcinoma with invasion of the lymph vessels,perineural invasion, and positive nodes(2/27); surgical margins showed tumor cells, and the tumor was classified as pT3 N1 M0 R1. The patient was treated with radiation of the tumor bed and capecitabine/oxaliplatin followed by gemcitabine and FOLFIRINOX. Seven months after surgery, a liver metastasis was detected and treatment with FOLFIRINOX was started. Four months after detection of the metastasis, the patient opted for additional treatment with VAE. Another month later, the metastasis was treated with radiofrequency ablation(RFA). Eight months later, the hepatic lesion recurred and was again treated with RFA. Thecontinuous VAE treatment was increased in dose, and the patient stayed recurrence-free for the next 39 mo in good health and working full-time(as of the time this case report was written).CONCLUSION We present the case of a patient with aPC with R1-resection with development of liver metastasis during the course of treatment who showed an overall survival of 63 mo and a relapse-free survival of 39 mo under increasing VAE therapy. The possible synergistic effect on tumor control of RFA treatment and immunestimulatory effects of VAE should be further investigated. | Paul G Werthmann Robert Kempenich Gerlinde Lang-Averous Gunver S Kienle | 2019 | World Journal of Gastroenterology2019，25，12： | 0 |
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