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284篇 您的检索式:作者名="Weissman M"
    题名 作者 年代 出处 被引量
1Elevated basal intestinal mucosal cytokine levels in asymptomatic first-degree relatives of patients with Crohn's disease显示文摘AIM To determine levels of cytokines incolonic mucosa of asymptomatic first degreerelatives of Crohn’s disease patients.METHODS Cytokines(Interleukin(IL)1-Beta,IL-2,IL-5 and IL-8)were measured using ELISAin biopsy samples of normal looking colonicmucosa of first degree relatives of Crohn’sdisease patients(n = 9)and from normalcontrols(n = 10)with no family history ofCrohn’s disease.RESULTS Asymptomatic first degree relativesof patients with Crohn’s disease had significantlyhigher levels of basal intestinal mucosalcytokines(IL-2,IL-5 and IL-8)than normalcontrols.Whether these increased cytokinelevels serve as phenotypic markers for a geneticpredisposition to developing Crohns diseaselater on,or whether they indicate early(pre-clinical)damage has yet to be further defined.CONCLUSION Asymptomatic first degreerelatives of Crohn’s disease patients have higherlevels of cytokines in their normal-lookingintestinal mucosa compared to normal controls,This supports the hypothesis that increasedcytokines may be a cause or an early event inthe inflammatory cascade of Crohns disease andare not merely a result of the inflammatoryprocess.Indaram AVK Nandi S Weissman S Lam S Bailey B Blumstein M Greenberg R Bank S 2000World Journal of Gastroenterology2000,6,1:8
2Formation of trace by-products in the premixed flames of CH3Cl - C2H4 显示文摘Weissman M Benson S W 1983J Phys Chem1983,87,2:1
3Alarm Correlation 显示文摘G Jakobson M D Weissman 1993IEEE Network1993,,:1
4Ubiquitin char- ging of human class III ubqintin-conjugating enzymes triggers their nuclear import 显示文摘Plaiker S M Plafker K S Weissman A M 2004Journal of Cell Biology2004,167,4:1
5The first probabilistic track of the international planning competition 显示文摘Younes H L S Littman M L Weissman D 2005Journal of Artificial Intelligence Research2005,24,1:1
6Regulating the p53 system through ubiquitination显示文摘YANG Y LI C C WEISSMAN A M 2004Oncogene2004,23,11:1
7SINAT5 promotes ubiquitin-related degradation of NAC1 to attenuate auxin signals显示文摘XIE Q GUO H S DALLMAN G FANG SH Y WEISSMAN A M CHUA N H 2002Nature2002,419,:1
8Screening for bipolar disorder in the community显示文摘Hirschfeld RMA Calabrese JR Weissman M 2003J Clin Psychiatry2003,64,1:1
9A cell-surface moleculemvalved in organ-specific homing of lymphocytes 显示文摘Callatin V M Weissman I L Butcher E L 1983Nature1983,304,:1
10Cross national epi- demiology of major depression and bipolar disorder 显示文摘Weissman M M Bland R C Canino G J 1996JAMA1996,276,4:1
11Working on a chain:E3s ganging up for ubiquitylation显示文摘Metzger M B Weissman A M 2010Nat Cell Biol2010,12,12:1
12Construction of libraries enriched for sequence repeats and jumping clones , and hybridization selection for region specific markers显示文摘Kandpal R P Kandpal G Weissman S M 1994Proc Natl Acid Sci USA1994,91,:1
13Alarm correlation显示文摘JAKOBSON G WEISSMAN M D 1993IEEE Network1993,7,11:1
14Resting metabolic rateof the critically ill patient : measured versus predicted 显示文摘Weissman C Kemper M Askanazi J 1986Anes- thesiology1986,64,6:1
15Stem cells, cancer, and cancer stem cells显示文摘Reya T Morrison S J Clarke M F Weissman I L 2001Nature2001,414,:1
16Journal of Colloid and Interface Science 显示文摘Reese C E Guerrero C D Weissman J M Lee K Asher S A 2000232(1): 762000,232,1:1
17Construction of libraries enriched for sequence repeats and jumping clones,and hybridization selection for region-specific markers显示文摘Kandpal R Kandpal G Weissman S M 1994Proc Natl Acad Sci USA1994,91,:1
18Pigmented vitlonodular synovitis 显示文摘Bravo S M Winalski C S Weissman B N 1996Radiol Clin North Am1996,34,2:1
19Duplication anomaly of the internal auditory canal显示文摘Weissman JL Arriaga M Curtin HD 0,,:1
20Thermally switchable periodici ties and diffraction from mesoscopically ordered materials 显示文摘Weissman J M Sunkara H B Tse A S 1996Science1996,274,:1
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