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| 1 | P2X7 receptor signaling during adult hippocampal neurogenesis显示文摘Neurogenesis is a persistent and essential feature of the adult mammalian hippocampus.Granular neurons generated from resident pools of stem or progenitor cells provide a mechanism for the formation and consolidation of new memories.Regulation of hippocampal neurogenesis is complex and multifaceted,and numerous signaling pathways converge to modulate cell proliferation,apoptosis,and clearance of cellular debris,as well as synaptic integration of newborn immature neurons.The expression of functional P2X7 receptors in the central nervous system has attracted much interest and the regulatory role of this purinergic receptor during adult neurogenesis has only recently begun to be explored.P2X7 receptors are exceptionally versatile:in their canonical role they act as adenosine triphosphate-gated calcium channels and facilitate calcium-signaling cascades exerting control over the cell via calcium-encoded sensory proteins and transcription factor activation.P2X7 also mediates transmembrane pore formation to regulate cytokine release and facilitate extracellular communication,and when persistently stimulated by high extracellular adenosine triphosphate levels large P2X7 pores form,which induce apoptotic cell death through cytosolic ion dysregulation.Lastly,as a scavenger receptor P2X7 directly facilitates phagocytosis of the cellular debris that arises during neurogenesis,as well as during some disease states.Understanding how P2X7 receptors regulate the physiology of stem and progenitor cells in the adult hippocampus is an important step towards developing useful therapeutic models for regenerative medicine.This review considers the relevant aspects of adult hippocampal neurogenesis and explores how P2X7 receptor activity may influence the molecular physiology of the hippocampus,and neural stem and progenitor cells. | Hannah C. Leeson Tailoi Chan-Ling Michael D. Lovelace Jeremy C. Brownlie Ben J. Gu Michael W. Weible II | 2019 | Neural Regeneration Research2019，14，10： | 3 |
| 2 | Galantamine facilitates acquisition of hippocampus-dependent trace eyeblink conditioning in aged rabbits显示文摘 | Weible A P Oh M M Lee G | 2004 | Learn Mem2004，11，1： | 1 |
| 3 | A Prospective Evaluation of Pain Associated With Stone Passage, Stents, and Stent Removal Using a Visual Analog Scale显示文摘 | Franklin E. Kuehhas Arkadus Miernik Varun Sharma Sabina Sevcenco Elchin Javadli Ralf Herwig Tibor Szarvas Martin Schoenthaler Georg Schatzl Peter Weibl | 2013 | Urology2013，，3： | 1 |
| 4 | Perceptions and practice of waterbirth:a survey of Georgia midwives显示文摘 | Meyer SL Weible CM Woeher K | | 0，，01： | 1 |
| 5 | Needles in a haystack:using interlibrary loan data to identify materials missing from a library's collection显示文摘 | Atkins S S Weible C L | 2003 | library collections acquisitions &Technical Services2003，2003，27： | 1 |
| 6 | Connections of the caudal anterior cingulate cortex in rabbit:naural circuitry participating in the acquisition of trace eyeblink conditioning显示文摘 | Weible A P Weiss C Disterhoft J F | 2007 | Neuroscience2007，145，45： | 1 |
| 7 | Coalitions, Science, and Belief Change : Comparing Adversarial and Collaborative Policy Subsystems 显示文摘 | Weible Christopher M Paul Sabatier | 2007 | The Policy Studies Journal2007，37，2： | 1 |
| 8 | Fabrication of aspherical microlenses in fused silica and silicon 显示文摘 | Voelkel R Eisner M Weible K J | 2001 | SPIE2001，4440，： | 1 |
| 9 | Own not loan: different request sources for purchase lists显示文摘 | Erin S Silva Cherid L Weible | 2010 | Collection Management2010，35，34： | 1 |
| 10 | Echinococcus multilocularis a zoonosis of anthropogenic environments显示文摘 | Romig T Thoma D Weible A K | 2006 | J Helminthol2006，80，2： | 1 |
| 11 | Laparoscopic Cryoablation Versus Partial Nephrectomy for the Treatment of Small Renal Masses: Systematic Review and Cumulative Analysis of Observational Studies 显示文摘 | Tobias Klatte Bernhard Grubmüller Matthias Waldert Peter Weibl Mesut Remzi | 2011 | European Urology2011，，： | 1 |
| 12 | Fabrication of aspherical microlenses in fused silica and silicon 显示文摘 | VOELKEL R EISNER M WEIBLE K J | 2001 | Proc SPIE2001，4440，： | 1 |
| 13 | In sympathetic but not sensory neurones,phosphoinositide-3 kinase is important for NGF- dependent survival and the retrograde transport125 of I-beta NGF 显示文摘 | Bartlett SE Reynolds AJ Weible M | 1997 | Brain Res1997，761，2： | 1 |
| 14 | Miniaturized imaging systems 显示文摘 | Volkel R Eisner M Weible K J | 2003 | Microelectronic Engineering2003，6768，： | 1 |
| 15 | Complex renal cystic masses:current standards and controversies显示文摘 | Weibl P Klatte T Waldert M | 2012 | Int Urol Nephrol2012，44，1： | 1 |
| 16 | Laser beam homogenizing:limitations and constraints显示文摘 | VOELKEL R WEIBLE K J | 2008 | Proceedings of SPIE2008，7102，71： | 1 |
| 17 | External validation of the preoperative anatomical classification for prediction of complications related to nephron-sparing surgery显示文摘 | Matthias Waldert Sandra Waalkes Tobias Klatte Markus A. Kuczyk Peter Weibl Gerd Schüller Axel S. Merseburger Mesut Remzi | 2010 | World Journal of Urology2010，，4： | 1 |
| 18 | Echinococcus multilocularis-a zoonosis of anthropogenic environments 显示文摘 | Romig T Thoma D Weible AK | 2006 | J Helminthol2006，80，2： | 1 |
| 19 | Echinococcus multilocularis-a zoonosis of an thropogenic environments 显示文摘 | Romig T Thoma D Weible AK | 2006 | Helminthol2006，80，2： | 1 |
| 20 | Aging-related changes in astrocytes in the rat retina:imbalance between cell proliferation and cell death reduces astrocyte availability 显示文摘 | Mansour H Chamberlain C G Weible M N | 2008 | Aging Cell2008，7，4： | 1 |
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