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| 1 | Understanding development and ripening of fruit crops in an‘omics’ era显示文摘Next generation sequencing has revolutionized plant biology.Not only has our understanding of plant metabolism advanced using model systems and modern chromatography,but application of‘omics’-based technology has been widely extended to non-model systems as costs have plummeted and efficiency increased.As a result,important fundamental questions relating to important horticultural crops are being answered,and novel approaches with application to industry are in progress.Here we review recent research advances on development and ripening of fruit crops,how next generation sequencing approaches are driving this advance and the emerging future landscape. | Nigel E Gapper James J Giovannoni Christopher B Watkins | 2014 | Horticulture Research2014，1，1： | 4 |
| 2 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 3 | Taste-aversion conditioning of house mice (Mus domesticus) using the non-lethal repellent, cinnamamide显示文摘 | Watkins R W Gurney J E Cowan D P | 1998 | Appl Anim Behav Sci1998，，57： | 2 |
| 4 | Microbial population dynamics of in- oculated low-grade chalcopyrite bioleaching columns 显示文摘 | Mutch L Watling H Watkin E | 2010 | Hydrometal- lurgy2010，104，34： | 1 |
| 5 | HIF-- 1 mediates pathogenic inflammatory response to intestinal ischemia--reperfusion injury显示文摘 | Fernman R Deitch E A Watkins A C | 2010 | Am J Physiol2010，299，4： | 1 |
| 6 | Fine needle aspiration cytology of adrenocoaical oncocytic neoplasm: a case report显示文摘 | Chain E Watkin W Goldschmidt R | 2010 | Acta Cytol2010，54，4： | 1 |
| 7 | Periodic magnetization instabilities in a superconducting Nb film witha square lattice of Nidots显示文摘 | WATKINS D B DE LONG L E | 2000 | PhysRevB2000，61，： | 1 |
| 8 | The effects of interleukin-7 on the lymphangiogenic properties of human endothelial cells显示文摘 | Al-Rawi M A Watkins G Mansel R E | 2005 | Int J Oncol2005，27，3： | 1 |
| 9 | Substrate specificity of the oxidoreductase ERp57 is determined primarily by its interaction with calnexin and calreticulin显示文摘 | Jessop C E Tavender T J Watkins R H | 2009 | Journal of Biological Chemistry2009，284，4： | 1 |
| 10 | Experimental models of gram-negative sepsis显示文摘 | Parker S J Watkins P E | 2001 | Br J Surg2001，88，1： | 1 |
| 11 | Adaptive and maladaptive self-fo- cus in depression显示文摘 | Watkins E Teasdale JD | 2004 | Journal of Affective Disorders2004，82，1： | 1 |
| 12 | A line balancing heuristic case study for existing automated surface mount assembly line setups显示文摘 | Watkins R E Cochran J K | 1995 | Computers & Industrial Engineering1995，29，1： | 1 |
| 13 | Concurrent cisplatin- based radiotherapy and chemotherapy for locally advanced cervical cancer 显示文摘 | Rose P G Bundy B N Watkins E B | 1999 | N EnglJ Med1999，340，15： | 1 |
| 14 | Audit quality : a synthesis of theory and empirical evidence 显示文摘 | Watkins A L Hillison W Moeecroft S E | 2004 | Journal of Ac- counting Literature2004，23，： | 1 |
| 15 | Where is my bus? impact of mobile real time information on the perceived and actual waite time of transit riders 显示文摘 | Watkins K E Ferris B Borning A | 2011 | Transportation Research Part A2011，45，： | 1 |
| 16 | Rumination and executive function in depression: An experimental study 显示文摘 | Watkins E Brown RG | 2002 | J Neurol Neurosurg Psychiatry2002，72，3： | 1 |
| 17 | Experimental models of gram-negative sepsis显示文摘 | Parker S J Watkins P E | 2001 | Br J Surg2001，88，： | 1 |
| 18 | Effect of Ingredients and Processing Parameters on Pellet Quality显示文摘 | Briggs J L Maier D E Watkins B A | 1999 | Poultry Seienee1999，78，10： | 1 |
| 19 | Skeletal Muscle Lipid Content and Oxidative Enzyme Activity in Relation to Muscle Fiber Type in Type 2 Diabetes and Obesity显示文摘 | HE J WATKINS S DAVID E K | 2001 | Diabetes2001，50，4： | 1 |
| 20 | Comparison of stearidonic acid and α-linolenic acid on PGE2 production and COX-2 protein levels in MDA-MB-231 breast cancer cell cul- tures显示文摘 | Horia E Watkins B A | 2005 | Nutr Biochem2005，16，3： | 1 |
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