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10篇 您的检索式:作者名="Wasek"
    题名 作者 年代 出处 被引量
1查看详情显示文摘Krawczyk H Wasek K Kedzia J Wojciechowski J Wolf W.M 0,,:1
2Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice 显示文摘Sontag JM Wasek B Taleski G 2014Frontiers in Aging Neuroscience2014,6,214:1
3Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase(MTHFR)defi cient mice显示文摘Sontag JM Wasek B Taleski G 2014Front Aging Neurosci2014,6,214:1
4Brain-blood amino acid correlates following protein /estriction in murine maple syrup u- fine disease显示文摘Vogel KR Arning E Wasek BL 2014Orphanet J Rare Dis2014,9,:1
5Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase(MTHFR)deficient mice显示文摘Sontag JM Wasek B Taleski G 2014Front Aging Neurosci2014,6,:1
6Long-term therapy using beclomethasone preparations in our experience 显示文摘Frank-Piskorska A Wasek Z Malinowski R 1988Pneumonol Pol1988,56,11:1
7Cerebral Abscesses and Septic Pulmonary Emboli due to Serratia marcescens Infection Arising from a Portacath显示文摘Wasek Faisal Georgina Burnton Louise Imlay-Gillespie John Robilliard 2010Journal of Microbiology, Immunology and Infection2010,,6:1
8Abstracts in Isocyclic Compounds Base-catalyzed Ethanolysis of Diethoxyphosphoryllactones: A Facile Synthesis of Cyclpropanecarboxylates显示文摘KRAWCZYK H WASEK K KEDAIA J 2005Synlett2005,17,:1
9Acute administration of L-DOPA induces changes in methylation metabolites,reduced protein phosphatase 2A methylation,and hyperphosphorylation of Tau protein in mouse brain显示文摘Bottiglieri T Arning E Wasek B 2012J Neurosci2012,32,27:1
10Maternal dietary deficiencies in folic acid or choline worsen stroke outcomes in adult male and female mouse offspring显示文摘Maternal one-carbon metabolism plays an important role in early life programming.There is a well-established connection between the fetal environment and the health status of the offspring.Howeve r,there is a knowledge gap on how maternal nutrition impacts stro ke outcomes in offspring.The aim of our study was to investigate the role of maternal dietary deficiencies in folic acid or choline on stroke outcomes in 3-month-old offspring.Adult female mice were fed a folic acid-deficient diet,choline-deficient diet,or control diet 4 weeks before pregnancy.They we re continued on diets during pregnancy and la ctation.Male and female offspring were weaned onto a control diet and at 2 months of age were subjected to ischemic stroke within the sensorimotor cortex via photothrombotic damage.Mothers maintained on either a folic acid-deficient diet or choline-deficient diet had reduced levels of S-adenosylm ethionine in the liver and S-adenosylhomocysteine in the plasma.After ischemic stro ke,motor function was impaired in 3-month-old offspring from mothers receiving either a folic acid-deficient diet or choline-deficient diet compared to the animals receiving a control diet.In brain tissue,there was no difference in ischemic damage volume.When protein levels were assessed in ischemic brain tissue,there were lower levels of active caspase-3 and hypoxia-inducible factor 1α in males compared to females and betaine levels were reduced in offspring from the mothers receiving a choline-deficient diet.Our results demonstrate that a deficient maternal diet at critical time points in neurodevelopment results in worse stro ke outcomes.This study emphasizes the importance of maternal diet and the impact it can have on offspring health.McCoy Clementson Lauren Hurley Sarah Coonrod Calli Bennett Purvaja Marella Agnes S.Pascual Kasey Pull Brandi Wasek Teodoro Bottiglieri Olga Malysheva Marie A.Caudill Nafisa M.Jadavji 2023Neural Regeneration Research2023,18,11:0
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