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| 1 | Role of post-translational modification of the Y box binding protein 1 in human cancers显示文摘Y box binding protein-1(YBX1)belongs to a DNA-and RNA-binding family of transcription factors,containing the highly conserved cold shock domain(CSD).YBX1 is involved in a number of cellular functions including transcription,translation,DNA damage repair etc.,and it is upregulated during times of environmental stress.YBX1 is localized in both the cytoplasm and the nucleus.There,its nuclear translocation is observed in a number of cancers and is associated with poor prognosis and disease progression.Additionally,YBX1 expression is upregulated in a variety of cancers,pointing towards its role as a potential oncogene.Under certain circumstances,YBX1 also promotes the expression of multidrug resistance 1(MDR1)gene,which is involved in the development of drug resistance.Thus,it is critical to understand the mechanism of YBX1 regulation and its downstream effects on promoting cancer development.A number of recent studies have highlighted the mechanisms of YBX1 regulation.Mass spectrometric analyses have reported several post-translational modifications that possibly play an important role in modulating YBX1 function.Phosphorylation is the most widely occurring post-translational modification in YBX1.In vivo analyses of sites like S102 and more recently,S165 illustrate the relationship of post-translational regulation of YBX1 in promoting cell proliferation and tumor growth.This review provides a comprehensive and up-to-date account of post-translational modifications identified in YBX1.This knowledge is a key in allowing us to better understand the mechanism of YBX1 regulation,which will aid in development of novel therapeutic strategies to target YBX1 in many types of cancer in the future. | Lakshmi Prabhu Antja-Voy Hartley Matthew Martin Fadumo Warsame Emily Sun Tao Lu | 2015 | Genes & Diseases2015，2，3： | 3 |
| 2 | Treatment options for advanced pancreatic cancer: a review 显示文摘 | Warsame R Grothey A | 2012 | Expert Rev Anticancer Ther2012，12，10： | 1 |
| 3 | Efficacy of monotherapies and artesunate-based combination therapies in children with uncomplicated malaria in Somalia 显示文摘 | WARSAME M ATrA H KLENA J D | 2009 | Acta Trop2009，109，2： | 1 |
| 4 | Managing Public Impressions : Environmental Disclosures in Annual Reports 显示文摘 | Neu D Warsame H Pedwell K | 1998 | Accounting Organizations and Society1998，23，3： | 1 |
| 5 | Managing Public Impressions: Environmental Disclosures in Annual Reports显示文摘 | Neu D Warsame H and Pedwell K | 1998 | Accounting Organizations and Society1998，，： | 1 |
| 6 | ' Managing public impres- sions: environmental disclosure in annual reports' Accounting 显示文摘 | Neu D Warsame H Pedwell K | 1998 | Organizations and Society1998，23，3： | 1 |
| 7 | Treatment options for advanced pancreatic cancer:a review显示文摘 | Warsame R Grothey A | 2012 | Expert Rev Anticancer Ther2012，12，10： | 1 |
| 8 | Effectiveness of a community intervention on malaria in rural Tanzania a randomized con- trolled trial显示文摘 | Eriksen J Mujinja P Warsame M | 2010 | Afric Health Sci2010，10，4： | 1 |
| 9 | The accuracy of canadian and new zealand earnings forecasts: A comparison of voluntary versus compulsory disclosures显示文摘 | Pedwell K Warsame H Neu D | 1994 | Journal of International Accounting Auditing and Taxation1994，，3： | 1 |
| 10 | Capsaicin-evoked substance P release in rat dorsal horn increases after peripheral inflammation: a microdialysis study显示文摘 | Warsame Afrah A Gustafsson H Olgart L | 2004 | Neurosci Lett2004，368，2： | 1 |
| 11 | Trends and out- comes of modern staging of solitary plasmacytoma of bone 显示文摘 | Warsame R Gertz MA Lacy MQ | 2012 | Am J Hematol2012，87，7： | 1 |
| 12 | Load Disturbance Resistance Speed Controller Design for PMSM显示文摘 | ZHANG Yongpeng Cajetan M Akujuobi Warsame H Ali | | 0，，04： | 1 |
| 13 | Evaluation of right ventricular global and regional function during stress echoeardiography using novel velocity vector imaging显示文摘 | Yang HS Mookadam F Warsame TA | | Eur J Echocardiogr0，1，2： | 1 |
| 14 | Impact of training in clinical and microscopy diagnosis of childhood malaria on antimalarial drug prescription and health outcome at primary health care level in Tanzania:a randomized controlled trial显示文摘 | Ngasala B Mubi M Warsame M | 2008 | Malar J2008，7，： | 1 |
| 15 | Evaluation of right ventricular global and regional function during stress echocardiography using novel velocity vector imaging显示文摘 | Yang HS Mookadam F Warsame TA | | 0，，： | 1 |
| 16 | Abnormal FISH in patients with immunoglobulin light chain amyloidosis is a risk factor for cardiac involvement and for death显示文摘 | Warsame R Kumar SK Gertz MA | 2015 | Blood Cancer2015，5，： | 1 |
| 17 | IL-33 is negatively associated with the BMI and confers a protective lipid/metabolic profile in non-diabetic but not diabetic subjects显示文摘 | Hasan A Al-Ghimlas F Warsame Sv | 2014 | BMC Immunol2014，10，5： | 1 |
| 18 | Managing Public Impressions: Environmental Disclosures in Annual Reports 显示文摘 | Neu D Warsame H Pedwell K | 1998 | Accounting Organizations and Society1998，23，3： | 1 |
| 19 | Trends and outcomes of modern staging of solitary plasmacytoma of bone显示文摘 | Rahma Warsame Morie A. Gertz Martha Q. Lacy Robert A. Kyle Francis Buadi David Dingli Philip R. Greipp Suzanne R. Hayman Shaji K. Kumar John A. Lust Stephen J. Russell Thomas E. Witzig Joseph Mikhael Nelson Leung Steven R. Zeldenrust S. Vincent Rajkumar A | 2012 | Am. J. Hematol2012，，7： | 1 |
| 20 | Capsaicin2evoked substance P release in rat dorsal horn increases after peripheral in-flammation:a microdialysis study显示文摘 | Warsame Afrah A Gustafsson H Olgart L | 2004 | Neurosci Lett2004，368，2： | 1 |
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