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| 1 | Relation of atrophic gastritis with Helicobacter pylori-CagA^+ and interleukin-1 gene polymorphisms显示文摘AIM: To determine the association of Helicobacter pylori (H pylori) CagA+ infection and pro-inflammatory poly-morphisms of the genes interleukin (IL)-1RN and IL-1B with the risk of gastric atrophy and peptic ulcers in a dyspeptic population in Costa Rica, a country with high incidence and mortality of gastric cancer. METHODS: Seven biopsy specimens, a fasting blood sample and a questionnaire concerning nutritional and sociodemographic factors were obtained from 501 con-secutive patients who had undergone endoscopy for dyspeptic symptoms. A histopathological diagnosis was made. Pepsinogen concentrations were analyzed by enzyme linked immunosorbent assay (ELISA). Infection with H pylori CagA+ was determined by serology and polymerase chain reaction (PCR). IL-1B and IL-1RN polymorphisms genotyping was performed by PCR-restriction fragment length polymorphism (PCR-RFLP)and PCR respectively. RESULTS: In this dyspeptic population, 86% were H pylori positive and of these, 67.8% were positive for CagA. Atrophic antral gastritis (AAG) was associated with CagA+ status [odd ratio (OR) = 4.1; P < 0.000] and fruit consumption (OR = 0.3; P < 0.00). Atrophic body gastritis (ABG) was associated with pepsinogen PGI/PGII < 3.4 (OR = 4.9; P < 0.04) and alcohol consumption (OR = 7.3; P < 0.02). Duodenal ulcer was associated with CagA+ (OR = 2.9; P < 0.04) and smoking (OR = 2.4; P < 0.04). PGI < 60 μg/L as well as PGI/PGII < 3.4 were associated with CagA+. CONCLUSION: In a dyspeptic population in Costa Rica, H pylori CagA+ is not associated with ABG, but it is a risk factor for AAG. The pro-inflammatory cytokine poly-morphisms IL-1B + 3945 and IL-1RN are not associated with the atrophic lesions of this dyspeptic population. | Rafaela Sierra Clas Une Vanessa Ramírez Warner Alpízar-Alpízar María I González José A Ramírez Antoine de Mascarel Patricia Cuenca Guillermo Pérez-Pérez Francis Mégraud | 2008 | World Journal of Gastroenterology2008，14，42： | 2 |
| 2 | Maternal Serum Dioxin Levels and Birth Outcomes in Women of Seveso,Italy显示文摘 | Eskenazi B Mocarelli P Warner M | 2003 | Enviromental Health Perspectives2003，111，： | 1 |
| 3 | Parametric investigation of load-induced structure remodeling in the proximal femur显示文摘 | Marzban A Canavan P Warner G | 2012 | Proceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in Medicine2012，226，6： | 1 |
| 4 | Emergence of a new antibiotic resistance mechanism in India, Pakistan, and the UK: a molecular, biological, and epidemiological study 显示文摘 | Kumarasamy KK Toleman MA Walsh TR Bagaria J Butt F Balakrishnan R Chaudhary U Doumith M Giske CG Irfan S Krishnan P Kumar AV Maharjan S Mushtaq S Noorie T Paterson DL Pearson A Perry C Pike R Rao B Ray U Sarma JB Sharma M Sheridan E Thirunarayan MA Turton J Upadhyay S Warner M Welfare W Livermore DM Woodford N | 2010 | Lancet Infect Dis2010，10，9： | 1 |
| 5 | Bacteri- al RNA chaperones confer abiotic stress tolerance in plants and improved grain yield in maize under water-limited condi- tions显示文摘 | CASTIGLIONI P WARNER D BENSEN R J | 2008 | Plant Physiology2008，147，2： | 1 |
| 6 | Dietary factors affecting development of the ruminant stomach显示文摘 | Warner R G Flatt W P Loosli J K | 1956 | J Agr Food Chem1956，4，： | 1 |
| 7 | Loss of myosin Ⅵ reduces secretion and the size of the Golgi in fibroblasts from Snell' s waltzer mice显示文摘 | WARNER C L STEWART A LUZIO J P | 2003 | EMBO J2003，22，3： | 1 |
| 8 | Wildlife and the Illinois public: A bench-mark study of attitudes and perceptions显示文摘 | MANKIN P C WARNER R E ANDERSON W | 1999 | Wildlife Society Bulletin1999，27，： | 1 |
| 9 | Serum dioxin concent rations and endometriosis:a cohort study in Seveso, Italy 显示文摘 | Eskenazi B OcareUi P Warner M | 2002 | Environ Health Perspect2002，110，7： | 1 |
| 10 | Surgical treatment of hidradenitis suppurativa: A 10-year experience显示文摘 | Kagan RJ Yakuboff KP Warner P | 2005 | Surgery2005，138，： | 1 |
| 11 | Use of haemolysis index to estimate potassium concentration in in - vitro haemolysed serum samples显示文摘 | Shepherd J Warner MH Poon P | 2006 | Clinical chemistry and laboratory medicine2006，44，7： | 1 |
| 12 | Serum dioxin concent rations and endometriosis:a cohort study in Seveso,Italy显示文摘 | Eskenazi B Ocarelli P Warner M | 2002 | Environ Health Perspect2002，110，7： | 1 |
| 13 | The major genetic determinants of HIV-1control affect HLA class I peptide presentation显示文摘 | International HIV Controllers Study Pereyra F Jia X McLaren P J Telenti A de Bakker P I Walker B D Ripke S Brumme C J Pulit S L Carrington M Kadie C M Carlson J M Heckerman D Graham R R Plenge R M Deeks S G Gianniny L Crawford G Sullivan J Gonzalez E Davies L Camargo A Moore JM Beattie N Gupta S Crenshaw A Burtt N P Guiducci C Gupta N Gao X Qi Y Yuki Y Piechocka-Trocha A Cutrell E Rosenberg R Moss K L Lemay P O'Leary J Schaefer T Verma P Toth I Block B Baker B Rothchild A Lian J Proudfoot J Alvino D M Vine S Addo M M Allen T M Altfeld M Henn M R Le Gall S Streeck H Haas D W Kuritzkes D R Robbins G K Shafer R W Gulick R M Shikuma C M Haubrich R Riddler S Sax P E Daar E S Ribaudo H J Agan B Agarwal S Ahern R L Allen B L Altidor S Altschuler E L Ambardar S Anastos K Anderson B Anderson V Andrady U Antoniskis D Bangsberg D Barbaro D Barrie W Bartczak J Barton S Basden P Basgoz N Bazner S Bellos N C Benson A M Berger J Bernard N F Bernard A M Birch C Bodner S J Bolan R K Boudreaux E T Bradley M Braun J F Brndjar J E Brown S J Brown K Brown S T Burack J Bush LM Cafaro V Campbell O Campbell J Carlson R H Carmichael J K Casey K K Cavacuiti C Celestin G Chambers S T Chez N Chirch L M Cimoch P J Cohen D Cohn LE Conway B Cooper D A Cornelson B Cox D T Cristofano M V Cuchural G Jr Czartoski J L Dahman J M Daly J S Davis B T Davis K Davod S M DeJesus E Dietz C A Dunham E Dunn M E Ellerin T B Eron J J Fangman J J Farel C E Ferlazzo H Fidler S Fleenor-Ford A Frankel R Freedberg K A French N K Fuchs JD Fuller J D Gaberman J Gallant J E Gandhi R T Garcia E Garmon D Gathe J C Jr Gaultier C R Gebre W Gilman F D Gilson I Goepfert P A Gottlieb M S Goulston C Groger R K Gurley T D Haber S Hardwicke R Hardy W D Harrigan P R Hawkins T N Heath S Hecht F M Henry W K Hladek M Hoffman R P Horton J M Hsu R K Huhn G D Hunt P Hupert M J Illeman M L Jaeger H Jellinger R M John M Johnson J A Johnson K L Johnson H Johnson K Joly J Jordan W C Kauffman C A Khanlou H Killian R K Kim A Y Kim D D Kinder C A Kirchner J T Kogelman L Kojic E M Korthuis P T Kurisu W Kwon D S LaMar M Lampiris H Lanzafame M Lederman M M Lee D M Lee J M Lee M J Lee E T Lemoine J Levy J A Llibre J M Liguori M A Little S J Liu A Y Lopez A J Loutfy M R Loy D Mohammed D Y Man A Mansour M K Marconi V C Markowitz M Marques R Martin J N Martin H L Jr Mayer K H McElrath M J McGhee T A McGovern B H McGowan K McIntyre D Mcleod GX Menezes P Mesa G Metroka CE Meyer-Olson D Miller A O Montgomery K Mounzer K C Nagami E H Nagin I Nahass R G Nelson M O Nielsen C Norene D L O'Connor D H Ojikutu B O Okulicz J Oladehin O O Oldfield E C Olender S A Ostrowski M Owen WF Jr Pae E Parsonnet J Pavlatos A M Perlmutter A M Pierce M N Pincus J M Pisani L Price L J Proia L Prokesch R C Pujet H C Ramgopal M Rathod A Rausch M Ravishankar J Rhame F S Richards C S Richman D D Rodes B Rodriguez M Rose R C 3rd Rosenberg E S Rosenthal D Ross P E Rubin D S Rumbaugh E Saenz L Salvaggio M R Sanchez WC Sanjana V M Santiago S Schmidt W Schuitemaker H Sestak P M Shalit P Shay W Shirvani V N Silebi V I Sizemore J M Jr Skolnik P R Sokol-Anderson M Sosman J M Stabile P Stapleton J T Starrett S Stein F Stellbrink H J Sterman FL Stone V E Stone D R Tambussi G Taplitz R A Tedaldi E M Telenti A Theisen W Torres R Tosiello L Tremblay C Tribble M A Trinh P D Tsao A Ueda P Vaccaro A Valadas E Vanig T J Vecino I Vega V M Veikley W Wade B H Walworth C Wanidworanun C Ward D J Warner D A Weber R D Webster D Weis S Wheeler D A White D J Wilkins E Winston A Wlodaver C G van't Wout A Wright D P Yang O O Yurdin D L Zabukovic B W Zachary K C Zeeman B Zhao M | 2010 | Science2010，330，6010： | 1 |
| 14 | Cold - Climate Constructed Wetlands显示文摘 | Mahlum T Jen8sen P D Warner W S | 1995 | Water Science and Teehnology1995，32，3： | 1 |
| 15 | SilverCoated nylon fiber as an antibacterial agent显示文摘 | MACKEEN P C PERSON S WARNER S C | | 0，，01： | 1 |
| 16 | Open randomised trial of prescribing strategies in managing sore throat显示文摘 | Little P Willamson I Warner G | | 0，，： | 1 |
| 17 | Dietary factors affecting development of the ruminant stomach显示文摘 | WARNER R G FLATT W P LOOSLI J K | 1956 | J Agr Food Chem1956，4，： | 1 |
| 18 | Activity of linezolid against multi-resistant Gram-positive bacteria from diverse hospitals in the United Kingdom显示文摘 | Johnson A P Warner M Livermore D M | 2000 | J Antimicrob Chemother2000，45，： | 1 |
| 19 | Successful treatment of inflammatory myofibroblastlc tumor with malignant transformation by surgical resection and chemotherapy显示文摘 | Dishop M K Warner B W Dehner L P | 2003 | J Pediatr Hematol2003，25，2： | 1 |
| 20 | kow-tmns shortening and spread fats produced by electrochemical hydrogenation 显示文摘 | LIST G R WARNER K PINTAURO P | 2007 | ] Am Oil Chem Soc2007，84，： | 1 |
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