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| 1 | Spinal cord biological safety of image-guided radiation therapy versus conventional radiation therapy显示文摘Tumor models were simulated in purebred Beagles at the T9-10 levels of the spinal cord and treated with spinal image-guided radiation therapy or conventional radiation therapy with 50 or 70 Gy total radiation. Three months after radiation, neuronal injury at the T9-10 levels was observed, including reversible injury induced by spinal image-guided radiation therapy and apoptosis induced by conventional radiation therapy. The number of apoptotic cells and expression of the proapoptotic protein Fas were significantly reduced, but expression of the anti-apoptotic protein heat shock protein 70 was significantly increased after image-guided radiation therapy compared with the conventional method of the same radiation dose. Moreover, the spinal cord cell apoptotic index positively correlated with the ratio of Fas/heat shock protein 70. These findings indicate that 3 months of radiation therapy can induce a late response in the spinal cord to radiation therapy; image-guided radiation therapy is safer and results in less neuronal injury compared with conventional radiation therapy. | Wanlong Xu Xilinbaoleri Hao Liu Ruozheng Wang Jingping Bai | 2012 | Neural Regeneration Research2012，7，35： | 23 |
| 2 | Review on carbon storage estimation of forest ecosystem and applications in China显示文摘Background:The accuracy in estimating forest ecosystem carbon storage has drawn extensive attention of researchers in the field of global climate change.However,incomparable data sources and various estimation methods have led to significant differences in the estimation of forest carbon storage at large scales.Methods:In this study,we reviewed fundamental types of forest carbon storage estimation methods and their applications in China.Results:Results showed that the major forest carbon storage estimation methods were classified into 3 major categories and 15 subcategories focusing on vegetation carbon storage estimation,soil carbon storage estimation,and litter carbon storage estimation,respectively.The application in China showed that there have been 3 development stages of research in China since the 1990s.Studies of forest carbon storage estimation in province scales were conducted more frequently in the northeastern,eastern and southwestern provinces such as Zhejiang,Heilongjiang and Sichuan with high forest coverage or large forest area.Inventory-based methods,soil type method,and biomass model were the main forest estimation methods used in China,focusing on vegetation,soil and litter carbon storage estimation respectively.Total forest carbon storage of China was approximate 28.90 Pg C,and the average vegetation carbon density(42.04±5.39 Mg·ha?1)was much lower than that of the whole world(71.60 Mg·ha?1).Vegetation carbon density from average biomass method was the highest(57.07 Mg·ha?1)through comparing nine types of vegetation carbon storage estimation methods applied during 1989 to 1993.Conclusions:Many studies on forest carbon storages have been carried out in China at patch scales or regional scales.These efforts enabled the research of forest carbon storage to reach a relatively advanced stage.Meanwhile,the accumulation of massive research data provides the basis for subsequent research work.Some challenges are also existing.This review could provide a reference for more accurate estimation of forest carbon storage in the future. | Wanlong Sun Xuehua Liu | 2020 | Forest Ecosystems2020，7，1： | 12 |
| 3 | A novel strategy for rapid construction of libraries of full-length antibodies highly expressed on mammalian cell surfaces显示文摘一个万用的哺乳动物的显示器系统的开发为有高亲密关系的功能的人的抗体的选择是必要的。这里,我们为能高效地在哺乳动物的房间表面上被表示的全身的抗体图书馆的快速的建设描述了新奇策略。通用向量 pDGB-HC-TM 被插入唯一的序列为兴趣的基因的突然发生在里面和突然发生外面由限制 endonucleases BsmBI, SfiI,和 BstXI 认出了的多重克隆的地点构造。 Cytomegalovirus 倡导者,为在许多哺乳动物的房间的蛋白质的高表示的一个通常使用的倡导者,被用来从导出血小板的生长驾驶插入的抗体基因和一个 transmembrane 领域的表示因素受体在框架被熔化到重链的C终点一致区域到抗体在哺乳动物的房间表面上表示了的锚。用这策略,我们构造了一个全身的人的抗体显示图书馆。DNA 顺序分析和表示分析显示图书馆构造了有 6.58 e 的组合可表现的、可检测的差异 ???汩 l 吗?? | Ye Zhou Zhen-Rui Chen Chang-Zheng Li Wei He Shuwen Liu Shibo Jiang Wen-Li Ma Wanlong Tan Chen Zhou | 2010 | Acta Biochimica et Biophysica Sinica2010，42，8： | 11 |
| 4 | Nitrogen Biological Cycle Characteristics of Seepweed(Suaeda salsa) Wetland in Intertidal Zone of Huanghe(Yellow) River Estuary显示文摘From April 2008 to November 2009,the nitrogen(N) cycle of plantsoil system in seepweed(Suaeda salsa) wetland in the intertidal zone of the Huanghe(Yellow) River estuary was studied.Results showed that soil N had sig-nificant seasonal fluctuations and vertical distribution,and the net N mineralization rates in topsoil were significantly different in growing season(p < 0.01).The N/P ratio(9.87 ± 1.23) of S.salsa was less than 14,indicating that plant growth was limited by N.The N accumulated in S.salsa litter at all times during decomposition,which was ascribed to the N immobilization by microbes from the environment.Soil organic N was the main N stock of plant-soil system,accounting for 97.35% of the total N stock.The N absorption and utilization coefficients of S.salsa were very low(0.0145 and 0.3844,respectively),while the N cycle coefficient was high(0.7108).The results of the N turnovers among compartments of S.salsa wetland showed that the N uptake amount of aboveground part and root were 7.764 g/m2and 4.332 g/m2,respectively.The N translocation amounts from aboveground part to root and from root to soil were 3.881 g/m2 and 0.626 g/m2,respectively.The N translocation amount from aboveground living body to litter was 3.883 g/m2,the annual N return amount from litter to soil was more than 0.125(-) g/m2(minus represented immobilization),and the net N mineralization amount in topsoil(0-15 cm) in growing season was 1.190 g/m2.The assessment of N biological cycle status of S.salsa wetland indicated that N was a very important limiting factor and the ecosystem was situated in unstable and vulnerable status.The S.salsa was seemingly well adapted to the low-nutrient status and vulnerable habitat,and the N quantitative relationships determined in the compartment model might provide scientific base for us to reveal the special adaptive strategy of S.salsa to the vulnerable habitat in the following studies. | SUN Zhigao MOU Xiaojie SUN Jingkuan SONG Hongli YU Xiang WANG Lingling JIANG Huanhuan SUN Wanlong SUN Wenguang | 2012 | Chinese Geographical Science2012，22，1： | 9 |
| 5 | CAD Model-Based Intelligent Inspection Planning for Coordinate Measuring Machines显示文摘As the market competition among enterprises grows intensively and the demand for high quality products increases rapidly, product quality inspection and control has become one of the most important issues of manufacturing, and improving the efficiency and accuracy of inspection is also one of problems which enterprises must solve. It is particularly important to establish rational inspection planning for parts before inspecting product quality correctly. The traditional inspection methods have been difficult to satisfy the requirements on the speed and accuracy of modern manufacturing, so CAD-based computer-aided inspection planning (CAIP) system with the coordinate measuring machines (CMM) came into being. In this paper, an algorithm for adaptive sampling and collision-free inspection path generation is proposed, aiming at the CAD model-based inspection planning for coordinate measuring machines (CMM). Firstly, using the method of step adaptive subdivision and iteration , the sampling points for the specified number with even distribution will be generated automatically. Then, it generates the initial path by planning the inspection sequence of measurement points according to the values of each point's weight sum of parameters, and detects collision by constructing section lines between the probe swept-volume surfaces and the part surfaces, with axis-aligned bounding box (AABB) filtering to improve the detection efficiency. For collided path segments, it implements collision avoidance firstly aiming at the possible outer-circle features, and then at other collisions, for which the obstacle-avoiding movements are planned with the heuristic rules, and combined with a designed expanded AABB to set the obstacle-avoiding points. The computer experimental results show that the presented algorithm can plan sampling points' locations with strong adaptability for different complexity of general surfaces, and generate efficient optimum path in a short time and avoid collision effectively. | DONG Yude LIU Daxin ZHAO Han WANG Wanlong WU Juan | 2011 | Chinese Journal of Mechanical Engineering2011，24，4： | 8 |
| 6 | Identification of HBsAg-specific antibodies from a mammalian cell displayed full-length human antibody library of healthy immunized donor显示文摘肝炎 B 免疫球蛋白(HBIG ) 在肝炎 B 的管理是重要的病毒(HBV ) 感染。试图作为 HBIG 的一种选择开发 recombinant monoclonal 抗体,我们报导 HBV 表面抗原(HBsAg ) 的成功的鉴定从在哺乳动物的房间上显示的一个全身的人的抗体图书馆的特定的抗体出现。把一个生来地使免疫的施主的外部血 mononuclear 房间的全部的 RNA 用作模板,抗体全部剧目被放大。联合四方法的结扎和 Flp 调停 recombinase 的集成(Flp 在里面) 系统,我们构造了每个房间在显示了一个种仅仅抗体分子的一个哺乳动物的基于房间的、充分人的、全身的抗体显示图书馆。由屏蔽使用激活荧光的房间排序的房间图书馆(FACS ) ,八个房间克隆显示那房间表面上的 HBsAg 特定的抗体被识别。抗体基因的 DNA 顺序分析揭示了三唯一的抗体。FACS 数据显示了那荧光灯表示(FSE ) 的力量,荧光灯绑定(FSB ) 的力量和相对有约束力的能力(RBA ) 都在他们之中是不同的。这些结果由使用我们的抗体表明了那哺乳动物的显示和屏蔽站台,我们能成功地从一个使免疫的全身的抗体图书馆识别抗原特定的抗体。因此,这个平台为治疗学的抗体的开发是很有用的。 | Chang-Zheng Li Zhong-Kun Liang Zhen-Rui Chen Hai-Bo Lou Ye Zhou Zhe-Huan Zhang Fei Yu Shuwen Liu Yuanping Zhou Shuguang Wu Wenling Zheng Wanlong Tan Shibo Jiang Chen Zhou | 2012 | Cellular & Molecular Immunology2012，9，2： | 7 |
| 7 | Four-way ligation for construction of a mammalian cell-based full-length antibody display library显示文摘唯一的四方法的结扎策略为一个全身的抗体图书馆的快速的建设被开发。哺乳动物的表示向量被构造盒子和序列由唯一的限制酶 BsmBI, BstXI,和 SfiI 认出了的那包含的双哺乳动物的表情。重链的基因的全身的轻链、可变的领域被四方法的结扎在一步插入到向量,并且全身的二原子价的抗体在哺乳动物的房间表面上被显示。用这策略,仅仅 2 个星期被要求成功地构造高质量的、全身的人的抗体图书馆。 | Ivan Zhou Zhe-Huan Zhang Chang-Zheng Li Zhen-Rui Chen Wei He Ye Zhou Shuwen Liu Shuguang Wu Yuanping Zhou Wanlong Tan Shibo Jiang Chen Zhou | 2011 | Acta Biochimica et Biophysica Sinica2011，43，3： | 6 |
| 8 | Three-dimensional conformal intensity-modulated radiation therapy of left femur foci does not damage the sciatic nerve显示文摘During radiotherapy to kill femoral hydatid tapeworms,the sciatic nerve surrounding the focus can be easily damaged by the treatment.Thus,it is very important to evaluate the effects of radiotherapy on the surrounding nervous tissue.In the present study,we used three-dimensional,conformal,intensity-modulated radiation therapy to treat bilateral femoral hydatid disease in Meriones meridiani.The focus of the hydatid disease on the left femur was subjected to radiotherapy(40 Gy) for 14 days,and the right femur received sham irradiation.Hematoxylin-eosin staining,electron microscopy,and terminal deoxynucleotidyl transferase-d UTP nick end labeling assays on the left femurs showed that the left sciatic nerve cell structure was normal,with no obvious apoptosis after radiation.Trypan blue staining demonstrated that the overall protoscolex structure in bone parasitized with Echinococcus granulosus disappeared in the left femur of the animals after treatment.The mortality of the protoscolex was higher in the left side than in the right side.The succinate dehydrogenase activity in the protoscolex in bone parasitized with Echinococcus granulosus was lower in the left femur than in the right femur.These results suggest that three-dimensional conformal intensity-modulated radiation therapy achieves good therapeutic effects on the secondary bone in hydatid disease in Meriones meridiani without damaging the morphology or function of the sciatic nerve. | Wanlong Xu Xibin Zhao Qing Wang Jungang Sun Jiangbo Xu Wenzheng Zhou Hao Wang Shigui Yan Hong Yuan | 2014 | Neural Regeneration Research2014，9，20： | 6 |
| 9 | SOME NEW RESULTS ON THE CONFIDENCELIMITS FOR RELIABILITY PARAMETERS IN THECASE OF NO FAILURES显示文摘In reliability tests, Type I censored data are common. For products of high quality, real life length is much longer than the censoring time. A group of items of some kind of product are put into reliability experiment. In case every item is censored,there is no failure. We refer to such data as No Failures. We construct lower confidence limits for life characteristics (such as average life, reliability, reliable span). This is done under the assumption of Weibull distribution, Lognormal distribution and nonparametric distribution family in the case of no failures. | SUN Wanlong CHEN Jiading (Department of Probability and Statistics, Peking University, Beijing 100871, China) | 1999 | Systems Science and Mathematical Sciences1999，12，1： | 5 |
| 10 | Improving the Local Sheep in Gansu via Crossing with Introduced Sheep Breeds Dorset and Borderdale显示文摘In order to improve the meat performance of local sheep in Gansu Province,Dorset and Borderdale were introduced to crossbreed with local sheep which were Tan sheep,Small-tail Han sheep and Mongolia sheep. The offspring under different crossbreeding combinations were sampled randomly at the different growing stage to measure their growth traits so as to select optimize the crossbreeding mode. The results indicated that,for the same crossbreeding mode,the growth rate of progeny was in order F3> F2> F1; for the F3 progeny,the combinations Dorset- Borderdale- Small tail Han sheep and Dorset- Borderdale- Mongolia sheep gave a higher growth rate,with a body weight of 1. 57%,3. 17%,8. 23%,1. 15% higher in male and female individuals than the counterparts of Dorset and Tan sheep and Small tail Han sheep; for the F2 progeny,the combinations Dorset- Borderdale- Small tail Han sheep and Dorset- Borderdale- Mongolia sheep also gave a higher growth rate,with a body weight of 2. 15%,4. 53%,9. 21% and 2. 75% higher in male and female individuals than the counterparts of Dorset and Tan sheep and Small tail Han sheep; for the F1 progeny,the combination Borderdale and Small tail Han sheep assumed a higher growth rate,with a body weight of 3. 23%,6. 07%,7. 42% and 8. 66% higher in male and female individuals than the counterparts of Borderdale- Mongolia sheep and Tan sheep- Small tail Han sheep,respectively. Therefore,in the Small-tail Han sheep and Mongolia sheep producing regions,the F2 or F3progeny bred by using Dorset or Borderdale sheep as male parent to cross with local breeds,or the hybrid lambs of Small-tail Han sheep and Borderdale sheep as highly qualified commodity,would produce significant economic benefit. Moreover,the novel breeds obtained by crossing were the valuable genetic resource for breeding meat sheep. | Sun Xiaoping Liu Jianbin Zhang Wanlong Lang Xia Yang Bohui Guo Jian Feng Ruilin | 2014 | Animal Husbandry and Feed Science2014，6，5： | 3 |
| 11 | Hybrid Dirac semimetal-based photodetector with efficient low-energy photon harvesting显示文摘Despite the considerable effort,fast and highly sensitive photodetection is not widely available at the low-photon-energy range(~meV)of the electromagnetic spectrum,owing to the challenging light funneling into small active areas with efficient conversion into an electrical signal.Here,we provide an alternative strategy by efficiently integrating and manipulating at the nanoscale the optoelectronic properties of topological Dirac semimetal PtSe_(2)and its van der Waals heterostructures.Explicitly,we realize strong plasmonic antenna coupling to semimetal states near the skin-depth regime(λ/10^(4)),featuring colossal photoresponse by in-plane symmetry breaking.The observed spontaneous and polarization-sensitive photocurrent are correlated to strong coupling with the nonequilibrium states in PtSe_(2)Dirac semimetal,yielding efficient light absorption in the photon range below 1.24 meV with responsivity exceeding∼0.2 A/W and noise-equivalent power(NEP)less than~38 pW/Hz^(0.5),as well as superb ambient stability.Present results pave the way to efficient engineering of a topological semimetal for high-speed and low-energy photon harvesting in areas such as biomedical imaging,remote sensing or security applications. | Lin Wang Li Han Wanlong Guo Libo Zhang Chenyu Yao Zhiqingzi Chen Yulu Chen Cheng Guo Kaixuan Zhang Chia-Nung Kuo Chin Shan Lue Antonio Politano Huaizhong Xing Mengjie Jiang Xianbin Yu Xiaoshuang Chen Wei Lu | 2022 | Light(Science & Applications)2022，11，3： | 2 |
| 12 | Does diffusion tensor data reflect pathological changes in the spinal cord with chronic injury?显示文摘Magnetic resonance diffusion tensor imaging has been shown to quantitatively measure the early pathological changes in chronic cervical spondylotic myelopathy.In this study,a novel spongy polyurethane material was implanted in the rat C3–5epidural space to establish a rat model of chronic cervical spondylotic myelopathy.Diffusion tensor data were used to predict pathological changes.Results revealed that the fractional anisotropy value gradually decreased at 4,24,and 72 hours and1 week after injury in rat spinal cord,showing a time-dependent manner.Average diffusion coefficient increased at 72 hours and 1 week after implantation.Hematoxylin-eosin staining and Luxol-fast-blue staining exhibited that the number of neurons in the anterior horn of the spinal cord gray matter and the nerve fiber density of the white matter gradually reduced with prolonged compression time.Neuronal loss was most significant at 1 week after injury.Results verified that the fractional anisotropy value and average diffusion coefficient reflected the degree of pathological change in the site of compression in rat models at various time points after chronic spinal cord compression injury,which potentially has a reference value in the early diagnosis of chronic cervical spondylotic myelopathy. | Erjian Lin Houqing Long Guangsheng Li Wanlong Lei | 2013 | Neural Regeneration Research2013，8，36： | 2 |
| 13 | Retavperitoneal lap- aroscopic pyelolithotomy and ureterolithotomy and 34 cases of 显示文摘 | Xiong Lin Tan Wanlong Peng Hongmei | 2006 | Chinese minimally invasive surg2006，24，6： | 1 |
| 14 | Study on Flow Characteristics of a Turbulent Boundary Layer and Vortex Structure of High Pressure Guide Vanes in SCO_2 Turbines显示文摘In order to further understand the aerothermodynamic performance and flow loss mechanism of SCO_2 turbines, RANS equations and an SST Turbulence Model were chosen for a numerical study on the secondary flow and vortex structure of cascades using the commercial software CFX. The dimensionless vorticity analysis method was used to study the flow characteristics of the logarithmic layer and viscous sublayer in high pressure guide vane cascades. The new vortex structure and formation mechanism of the vortices were given and analyzed. Simulation results indicated that during the motion of the boundary layer in the cascades, the logarithmic layer and viscous sublayer obtain the different rotational direction vorticity, respectively. The endwall logarithmic layer and pressure side leg of the horseshoe votex gradually develop into the passage vortex, with the endwall viscous sublayer gradually developing into the corner viscous sublayer vortex II and the endwall viscous sublayer vortex I. The endwall viscous sublayer that rolled by the passage vortex is encountered with the upstream-side and radial boundary layer of the vane at the suction separation line, forming the suction separation line vortex beside the passage vortex. A pair of radial transition vortices are formed between the wake and the main stream. | HAN Wanlong WANG Yueming FENG Zhenping LI Hongzhi YAO Mingyu ZHANG Yifan | 2019 | Journal of Thermal Science2019，28，3： | 1 |
| 15 | Map-based cloning of leaf rust resistance gene Lr21 from the large and polyploid genome of bread wheat显示文摘 | Huang L Steven A Wanlong L | 2003 | Genetics2003，164，： | 1 |
| 16 | MesoporouscarbonasanoveldrugcarrieroffenofibrateforenhanceGmentofthedissolutionandoralbioavailability显示文摘 | XiaNiu WanLong HouZhong etal | 2013 | IntJPharm2013，452，12： | 1 |
| 17 | Lin Shu' s Choice and Response in Translation from a Cultural Perspective 显示文摘 | Wanlong Gao | 2010 | The Journal of Spe- cialised Translation2010，13，： | 1 |
| 18 | Map-based cloning of leaf rust resistance gene Lr21 from the large and polyploid genome of bread wheat显示文摘 | Huang L Steven A Wanlong L | 2003 | Genetics2003，164，： | 1 |
| 19 | Map-based clo-ning of leaf rust resistance gene Lr21 from the largeand polyploid genome of bread wheat显示文摘 | Huang L Steven A Wanlong L | 2003 | Genetics2003，164，： | 1 |
| 20 | Complements as new diagnostic tools of hepatocellular Carcinoma in cirrhosis patients显示文摘 | Chang Wenyu Chuang Wanlong | 1988 | Cancer1988，62，： | 1 |
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