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| 1 | Epidemiologic study on human immunodeficiency virus infection among children in a former paid plasma donating community in China显示文摘Background Illegal plasma collecting activities in mid 1990s caused a large number of human immunodeficiency virus (HIV) infections in rural areas of central-eastern China. Although most of these activities have been stopped, there were few reports on secondary transmission from infected former plasma donors to their spouses and from infected mothers to their children. This study was to determine the extent of HIV infections among young children in a rural community with a large proportion of plasma donors.Methods A survey was conducted among children aged under 7 years in a former plasma donating community in September 2000: finger blood was collected for HIV antibody testing. Another survey was repeated among children aged under 8 years and their families in the same community in April 2001: urine samples were collected for HIV testing. HIV positive children and samples of HIV negative children, whose mothers were positive based on 2001 survey, were followed up until September 2002 to investigate HIV seroconversion, disease progression and HIV strain analysis. Questionnaires were administered to collect information on children’s delivery, breast feeding, medical history and their parents’ commercial blood donation history and HIV status.Results Among 169 children surveyed in 2000, 10 (5.9%) were HIV positive. Of 224 children, 11 were positive in 2001. The overall prevalence rate in the two surveys was 5.0% (17/337) when counting 56 repeated children only once. Of children born to HIV positive mothers, 28.9% were infected. A seroconversion rate of 2.5 per 100 child-years was observed by following up 28 HIV negative children. No statistically significant associations were found between children’s HIV infection and their histories of blood transfusion, surgery, immunization injection or medical injections. All infections were HIV-1 subtype B’ strain, the average dispersion rate is 7.4%. DNA sequence analysis showed a close relationship between the seroconverted children and their infected mothers.Conclusions HIV vertical transmissions in the rural former plasma donating community was significant. Intervention measures should be taken to prevent further transmission. It was estimated that the HIV spread in this community occurred in 1994 or even earlier. Many infected people are developing AIDS now: treatment and care are urgently needed for these sick people. | WANGLan ZHENGXi-wen QIANHan-zhu LüFan XINGHui | 2005 | Chinese Medical Journal2005，，9： | 9 |
| 2 | Therapeutic induction of angiogenesis by direct myocardial administration of an adenovirus vector encoding human hepatocyte growth factor gene and its safety显示文摘After the study in vitro and in rats, we assessed further the effects and safety of local angiogen therapy using intramyocardial delivery of an adenovirus carrying hepato-cyte growth factor gene (Ad-HGF) in a canine ischemia model. The angiogenic activity of Ad-HGF was evaluated from three aspects. First, the augmentation of collateral ves-sel development was assessed by angiography 30 d after sur-gery. The results showed that the density of collateral vessels in treated group was higher than that of control group. Sec-ondly, infarct size was evaluated by TTC staining and image analysis. The results showed that the infarct size of treated group was smaller than that of control group. Thirdly, the myocardial regional blood flow was determined by the method of colored microspheres. The results showed that the blood flow recovered to the level before ligation in treated group, but that of the control group was lower than normal level. In addition, during the study of chronic toxicity, we tested the anti-adenovirus antibodies by neutralization method. The antibodies yielded after the fourth injection decreased slowly from peak level and disappeared 12 weeks after drug withdrawal. Overall, Ad-HGF can promote an-giogenesis in ischemic myocardium and reduce infarct size. So this method may be considered as a therapeutic angio-genesis induction strategy for ischemic disease including myocardial infarction and peripheral artery disease. At the same time, Ad-HGF could induce the yield of anti-adenovirus antibodies to neutralize adenovirus, which may be the mechanism of adenovirus clearance. | WUDanli ZHANGYourong LAOMiaofen YUANLizhen WANGLan HAXiaoqin WUZuze | 2004 | Chinese Science Bulletin2004，49，14： | 2 |
| 3 | 显示文摘 | XIXing-lin(奚星林) WANGLan(王岚) LIXun(李荀) LIShuang(李双) HEJi-zi(何吉子) ZOUZhi-fei(邹志飞) | 2013 | 食品安全质量检测学报2013，4，1： | 1 |
| 4 | Hydration of calcium sulphoaluminate cement显示文摘 | Wanglan Glasser F P | 1996 | Adv Adv CemRes1996，8，31： | 1 |
| 5 | Shallow‐lacustrine sand‐rich deltaic depositional cycles and sequence stratigraphy of the Upper Triassic Yanchang Formation, Ordos Basin, China显示文摘 | ZouCaineng ZhangXingyang LuoPing WangLan LuoZhong LiuLiuhong | 2010 | Basin Research2010，，1： | 1 |
| 6 | Hydration of calcium sulphoaluminate cement显示文摘 | Wanglan Glasser F p | 1996 | Adv Adv CemRes1996，8，31： | 1 |
| 7 | A research on related questions of Chinese food cold chain development显示文摘 | Wanglan | 2008 | International Conference on Management of Commerce and Government2008，，8： | 1 |
| 8 | Calculation of CO2 emissions from cement production enterprises[J]显示文摘 | WANGLan(汪澜) | | 中国水泥0，，： | 1 |
| 9 | Complex Boronized Layer on the Hot-dip Aluminized Steels and Its Surface Performances显示文摘Plain carbon steels were dipped in molten aluminum bath at 720°C ±5°C and diffused for 1, 2.5 and 6 hours respectively and then boronized at 950°C for 6 hours. The oxidation, hot-corrosion and abrasion resistance behavior were examined. The experimental results showed the compounds of the aluminized layer, from the surface to the matrix, were composed of Fe2Al5 ( n -phase ) .. Fe3Al ( -phase ) and a phase. The microstructure of aluminized plus complex boronized were similar to that simplex boronized. The XRD analysis results indicated that there existed Fe2B> Fe2AlB2and Fe2Als in this kind of layer. The simplex aluminized layers still remained bright gray appearance when oxidized at 950°C, but complex boronized layer was not able to resist oxidization at the temperature. Both the layers of complex boronized and aluminized had the same anti-oxidization level in the circulative oxidization tests, and also good anti-corrosion ability in molten salt medium. Under dry abrasive conditions, wear resistance of complex boronized layer was superior to the aluminized layer. | LUOXin-min LIDian-kai WANGLan CHENKang-min | 2004 | 材料热处理学报2004，25，05B： | 0 |
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