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7篇 您的检索式:作者名="WChen"
    题名 作者 年代 出处 被引量
1Centrifugal force induced dynamics of a motorized high-speed spindle 显示文摘WCHEN J S HWANG Y W 2006The International Journal of Advanced Manufacturing Technology2006,30,12:1
2An electropolymerized nile blue sensing film-based nitrite sensor and application in food analysis 显示文摘wChen X W Fang W Chen Z L 2008Analytica Chimica Acta2008,623,2:1
3Cancer statistics in China, 2015显示文摘WChen R Zheng P D Baade 2016CA Cancer J Clin2016,,:1
4Microporosity Formation in Partially Melted Zone During Welding of High Nitrogen Austenitic Stainless Steels显示文摘Kamiya O Wchen Z 2003Metal of Materials Science2003,37,12:1
5Worldwide impacts of atmospheric vapor pressure deficit on the interannual variability of terrestrial carbon sinks显示文摘Interannual variability of the terrestrial ecosystem carbon sink is substantially regulated by various environmental variables and highly dominates the interannual variation of atmospheric carbon dioxide(CO_(2))concentrations.Thus,it is necessary to determine dominating factors affecting the interannual variability of the carbon sink to improve our capability of predicting future terrestrial carbon sinks.Using global datasets derived from machine-learning methods and process-based ecosystem models,this study reveals that the inter annual variability of the atmospheric vapor pressure deficit(VPD)was significantly negatively correlated with net ecosystem production(NEP)and substantially impacted the inter annual variability of the atmospheric CO_(2)growth rate(CGR).Further analyses found widespread constraints of VPD interannual variability on terrestrial gross primary production(GPP),causing VPD to impact NEP and CGR.Partial correlation analysis confirms the persistent and widespread impacts of VPD on terrestrial carbon sinks compared to other environmental variables.Current Earth system models underestimate the interannual variability in VPD and its impacts on GPP and NEP.Our results highlight the importance of VPD for terrestrial carbon sinks in assessing ecosystems'responses to future climate conditions.Bin He Chen Chen Shangrong Lin Wenping Yuan Hans WChen Deliang Chen Yafeng Zhang Lanlan Guo Xiang Zhao Xuebang Liu Shilong Piao Ziqian Zhong Rui Wang Rui Tang 2022National Science Review2022,9,4:1
6Deleterious effects of electron beam irradiation on development and reproduction of tomato/potato psyllids, Bactericera cockerelli显示文摘The potato/tomato psyllid Bactericera cockerelli causes serious damage to several solanaceous crops by direct feeding and vectoring Candidatus Liberibacter solanacearum,a bacterial pathogen.Electron beam(eBeam)irradiation is an environmentally friendly,chemical-free alternative method that is increasing in use for disinfestation of insect pests.We hypothesize that this irradiation technology will have detrimental effects on potato psyllid and thus impede its disease vectoring.To this end,we explored the effects of eBeam treatment ranging from 50 to 500 Gy on survival,development and reproduction of this pest.Impact on psyllids was apparently dose-dependent.When irradiated at 350 Gy,eggs could not hatch,1st instar nymphs failed to emerge,and although a small portion of irradiated 5th instar nymphs survived,the emerged adults were mostly deformed.Abnormality in eclosed adults suggests harmful effects of eBeam on metamorphosis.Reproduction was seriously impaired when female psyllids were exposed to eBeam at the 5th instar nymphal or young adult stage,presumably due to inability to form oocytes.In addition,reciprocal crosses between irradiated and untreated psyllids indicated that female psyllids were more radiosensitive than males to eBeam.Taken together,these findings indicate that eBeam negatively impacted potato psyllid development and reproduction,which would inevitably compromise its disease transmission capacity.A dose of 350 Gy can be considered as a reference dose for effective control of potato psyllids.Jiaxin Lei Jia Meng Ivy WChen Weining Cheng Andrea L.Beam Md-Sajedul Islam Woodward D.Bailey Suresh Pillai Keyan Zhu-Salzman 2020Insect Science2020,27,6:0
7Association between single nucleotide polymorphisms in deoxycytidine kinase and treatment response among acute myeloid leukaemia patients显示文摘Development of resistance to 1-beta-arabinofuranosylcytosine (AraC) is a major obstacle in the treatment of patients with acute myeloid leukaemia (AML). Deficiency of functional deoxycytidine kinase (dCK) plays an important role in AraC resistance in vitro. We screened 5378 bp sequences of the dCK gene, including all exons and the 5' flanking region, and identified two single nucleotide polymorphisms (SNPs) in the regulatory region (rSNPs) with high allele frequencies. These two rSNPs (-201 C>T and -360C>G) formed two major haplotypes. Genotyping with sequencing and MassARRAY system among 122 AML patients showed that those with -360CG/-201CT and -360GG/-201TT compound genotypes (n = 41) displayed a favourable response to chemotherapy whereas those with -360CC/-201CC (n= 81) tended to have a poor response (P = 0.025). Moreover, real-time quantitative reverse transcriptase-polymerase chain reaction showed that patients with -360CG/-201CT and -360GG/-201TT genotypes expressed higher level of dCK mRNA compared to those with the -360CC/-201CC genotype (P = 0.0034). Luciferase-reporter assay showed that dCK 5' regulatory region bearing -360G/-201T genotype alone had an eight-fold greater transcriptional activation activity compared to that with -360C/-201C genotype, whereas co-transfection of both -360G/-201T and -360C/-201C constructs mimicked the heterozygous genotype, which exhibited a four-fold greater activity compared to that with -360C/-201C. These results indicate that rSNP haplotypes of dCK gene may serve as a genetic marker for predicting drug responsiveness, which will be beneficial in establishing more effective AML chemotherapeutic regimens.JYShi ZZZhang SJZhu YMGu BWLi GBai XTGao XDHu JJin WHuang WChen ZChen 2005中国生物学文摘2005,19,6:0
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