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| 1 | Impact of machine perfusion of the liver on post-transplant biliary complications: A systematic review显示文摘AIM To review the clinical impact of machine perfusion(MP) of the liver on biliary complications post-transplantation, particularly ischaemic-type biliary lesions(ITBL). METHODS This systematic review was performed in accordance with the Preferred Reporting Systematic Reviews and MetaAnalysis(PRISMA) protocol. The following databases were searched: PubMed, MEDLINE and Scopus. The keyword 'liver transplantation' was used in combination with the free term 'machine perfusion'. Clinical studies reporting results of transplantation of donor human livers following ex situ or in situ MP were analysed. Details relating to donor characteristics, recipients, technique of MP performed and post-operative biliary complications(ITBL, bile leak and anastomotic strictures) were critically analysed.RESULTS Fifteen articles were considered to fit the criteria for this review. Ex situ normothermic MP was used in 6 studies, ex situ hypothermic MP in 5 studies and the other 4 studies investigated in situ normothermic regional perfusion(NRP) and controlled oxygenated rewarming. MP techniques which have per se the potential to alleviate ischaemia-reperfusion injury: Such as hypothermic MP and NRP, have also reported lower rates of ITBL. Other biliary complications, such as biliary leak and anastomotic biliary strictures, are reported with similar incidences with all MP techniques. There is currently less clinical evidence available to support normothermic MP as a mitigator of biliary complications following liver transplantation. On the other hand, restoration of organ to full metabolism during normothermic MP allows assessment of hepatobiliary function before transplantation, although universally accepted criteria have yet to be validated.CONCLUSION MP of the liver has the potential to have a positive impact on post-transplant biliary complications, specifically ITBL, and expand extended criteria donor livers utilisation. | Yuri L Boteon Amanda PCS Boteon Joseph Attard Lorraine Wallace Ricky H Bhogal Simon C Afford | 2018 | World Journal of Transplantation2018，8，6： | 2 |
| 2 | New Generation NSAIDs: The Benefit Without the Risk显示文摘 | WALLACE J L CHIN B C | 1997 | Drugs Today1997，33，： | 1 |
| 3 | Role of angiography following aneurysm surgery显示文摘 | MACDONALD R L WALLACE M C KESTLE J R | 1993 | J Neurosurg1993，79，： | 1 |
| 4 | Volatile organic compounds as breath biomarkers for active and passive smoking 显示文摘 | Gordon S M Wallace L A Brinkman M C | 2002 | Environ Health Perspect2002，110，7： | 1 |
| 5 | Lightweight materials for aircraft applications 显示文摘 | IMMARIGEON J P HOLT R T KOUL A K ZHAO L WALLACE W BEDDOES J C | 1995 | Material Characterization1995，35，1： | 1 |
| 6 | Exploratory spatial data analysis of regional seroprevalence of antibodies against epizootic hemorrhagic disease virus in cattle from Illinois and Indiana 显示文摘 | BOYER T C WARD M P WALLACE R L | 2008 | American Journal of Veterinary Research2008，69，： | 1 |
| 7 | Clostridum proteoclasticum: a ruminal bacteri- um that forms stearic acid from linoleic acid 显示文摘 | WALLACE R J CHAUDHARY L C MCKAIN N | 2006 | FEMS Microbiol Lett2006，265，： | 1 |
| 8 | Lightweight materials for aircraft applications 显示文摘 | HOLT R T KOUL A K ZHAO L WALLACE W BEDDOES J C IMMARIGEON J P | 1995 | Materials Characterization1995，35，1： | 1 |
| 9 | The vasxcular response to micromovement in expew rimental fracture显示文摘 | Wallace A L Draper E R C Strachen R K | 1992 | Micromovement in Orthopac Dios London Oxfotrd1992，3，1： | 1 |
| 10 | Epstein-Barr virus-positive Burkitt's lymphoma cells not recognized by virus-specific T-cell surveillance显示文摘 | Rooney C M Rowe M Wallace L E | 1985 | Nature1985，317，： | 1 |
| 11 | The research core of the knowledge management literature显示文摘 | Wallace D P Van Fleet C Downs L J | 2011 | International Jour- nal of Information Management2011，31，1： | 1 |
| 12 | Volatile organic compounds as breath markers for active and passive smoking显示文摘 | Gordon S M Wallace L A Brinkman M C | 2002 | Environmental Health Perspectives2002，110，7： | 1 |
| 13 | Plastic deformation in metal powder compaction显示文摘 | WALLACE W MALHERBE M C | 1974 | Powder Metallurgy1974，17，33： | 1 |
| 14 | Evaluating tree detection and segmentation routines on very high resolution UAV LiDAR data显示文摘 | WALLACE L LUCIEER A WATSON C S | 2014 | IEEE Transactions on Geoscience & Remote Sensing2014，52，12： | 1 |
| 15 | Plastic deformation in metal powder compaction显示文摘 | WALLACE W MALHERBE M C | 1974 | Powder Metallurgy1974，17，33： | 1 |
| 16 | CEO regula- tory foci, environmental dynamism, and small firm performance显示文摘 | Wallace J C Little L M Hill A D | 2010 | Journal of Small Management2010，48，4： | 1 |
| 17 | Use of micro-lysimeters to measure evaporation from sandy soils显示文摘 | Daamen C C Simmonds L P Wallace J S | 1993 | Agricultural and Forest Meteorology1993，65，： | 1 |
| 18 | E- valuating factors that affect FCC stripper behaviour in a laboratory fluidised--bed reactor显示文摘 | SNAPE C E DIAZ M C WALLACE C L | 2004 | Studies in Surface Science and Catalysis2004，149，： | 1 |
| 19 | Intraperitoneal blood exacerbates the remote inflammatory response to murine peritonitis显示文摘 | JOHNSON T L WALLACE B H MAREEN C D | 2001 | J Trauma2001，51，2： | 1 |
| 20 | Lightweight materials for aircraft applications 显示文摘 | IMMARIGEON J P HOLT R T KOUL A K ZHAO L WALLACE W BEDDOES J C | 1995 | Materials Characterization1995，35，1： | 1 |
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