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| 1 | Formation history and protolith characteristics of granulite facies metamorphic rock in Central Cathaysia deduced from U-Pb and Lu-Hf isotopic studies of single zircon grains显示文摘The petrochemical as well as zircon U-Pb and Lu-Hf isotopic studies of granulite facies metamorphic rock from the Taoxi Group in eastern Nanling Range, Central Cathaysia indicate that its protolith is the sedimentary rock with low maturation index. The clastic materials are mostly from middle Neoproterozoic (~736 Ma) granitoid rocks with minor Neoarchaean and Paleoproterozoic rocks. The timing of this Neoproterozoic magmatism is in agreement with the second period of magmatism widespread surrounding the Yangtze Block. Hf isotopic data indicate that the Neoproterozoic granitoids resulted from the recycled Paleoproterozoic mantle-derived crustal materials. The sedimentary rock was deposited in Late Neoproterozoic Era, and carried into low crust in Early Paleozoic. The partial melting of the meta-sedimentary rock took place at about 480 Ma and subsequently granulite facies metamorphism occurred at ca. 443 Ma. The zircons forming during this time interval (Early Paleozoic) show large Hf isotope variations, and their -Hf(t) values increase from -13.2 to +2.36 with decreasing age, suggesting the injection of mantle-derived materials during partial melting and metamorphism processes in the Early Paleozoic. Calculation results show that this metamorphic rock, if evolved to Mesozoic, has similar isotopic composition to the nearby Mesozoic high Si peraluminous granites, implying that this kind of granulite facies metamorphic rock is probably the source material of some Mesozoic peraluminous granitoids in eastern Nanling Range. | YU Jinhai ZHOU Xinmin Y. S. O'Reilly ZHAO Lei W. L. Griffin WANG Rucheng WANG Lijuan CHEN Xiaomin | 2005 | Chinese Science Bulletin2005，50，18： | 35 |
| 2 | Prevalence and characterization of class I integrons among Pseudomonas aeruginosa and Acinetobacter baumanhii isolates from patients in Nanjing, China显示文摘 | Gu,B. Tong, M. Q. Zhao, W. J. Liu, G. Y. Ning, M. Z. Pan, S. Y. Zhao, W. | 2007 | 南京医科大学学报(自然科学版)2007，27，4： | 31 |
| 3 | Blockade of cholecystokinin-2 receptor and cyclooxygenase-2 synergistically induces cell apoptosis, and inhibits the proliferation of human gastric cancer cells in vitro显示文摘Gastrin and cyclooxygenase-2(COX-2) playimportant roles in the carcinogenesis and progression ofgastric cancer.However,it remains unknown whether the combination of cholecystokinin-2(CCK-2) receptor antagonist plus COX-2 inhibitor exerts synergistic anti-tumor effects on human gastric cancer.Here,we demonstrated that the combination of AG-041R(a CCK-2 receptor antagonist) plus NS-398(a selective COX-2 inhibitor) treatment had synergistic effects on proliferation inhibition,apoptosis induction,down-regulation of Bcl-2 and up-regulation of Bax expression in MKN-45 cells.These results indicate that simultaneous targeting of CCK-2 receptor and COX-2 may inhibit gastric cancer development more effectively than targeting either molecule alone.(C)2008 Elsevier Ireland Ltd.All rights reserved. | Sun, W. H. | 2008 | 南京医科大学学报(自然科学版)2008，28，9： | 30 |
| 4 | EFFECT OF Mo AND Mo_2C ON THE MICROSTRUCTURE AND PROPERTIES OF THE CERMETS BASED ON Ti(C,N)显示文摘Ti 的微观结构和性质上的瞬间和 Mo2C 的效果(C, N ) 基于的金属陶瓷在这篇文章被调查。结果显示了从 5~10 罐头的瞬间的重量百分比减少 Ti ( C , N )谷物直径和边界的厚度,和 Ti ( C , N )谷物能被 Ni-Cu-Mo 液体弄湿以便得到 Ti 的小邻近( C , N )谷物。因为 Ti 的横向的破裂力量(C, N ) 基于的金属陶瓷到达了 1800 1900 MPa;破裂坚韧由于 16 18 MPa · m 1/2。但是 15 wt % 瞬间不在 Ti 上是更有效的(C, N ) 基于的金属陶瓷,因为边界的厚度变得更大。在 Mo2C 的情形, 5 wt % Mo2C 对 Ti 的微观结构和性质好( C , N )基于的金属陶瓷,而是 11 wt % Mo2C 导致了 Ti 的更大的邻近( C , N )谷物和大 Ti ( C , N )谷物直径以便减少横向的破裂力量和破裂坚韧。以便, Ti 上的瞬间的效果(C, N ) 基于的金属陶瓷比 Mo2C 好。 | S.Q. Zhou W. Zhao W.H. Xiong Y.N. Zhou | 2008 | Acta Metallurgica Sinica(English Letters)2008，21，3： | 12 |
| 5 | Nature:研究鉴定出蛋白Nlrp9b抵抗轮状病毒感染机制显示文摘轮状病毒(rotavirus)是婴儿和儿童罹患肠胃炎和腹泻的一种最为常见的原因,每年导致全世界大约21.5万人死亡。它是高度传染性的和潜在致命性的。这种病毒特异性地感染宿主小肠中的肠上皮细胞,并且已进化出抵抗干扰素和NF-KB信号的策略来躲避免疫系统,这就提出一个问题:其他的宿主因子是否参与肠道粘膜中的抗病毒反应。不过,针对体内(特别是通过NLR炎性体)检测和限制肠道病毒的机制,人们知之甚少。 | Shu Zhu, Zheng Wei, Noah W. Palm, Yi Yang, Hua Yu, Hua-Bing Li, Geng Wang, Xuqiu Lei, Marcel R. de Zoete, Jun Zhao, Yunjiang Zheng, Haiwei Chen, Liang Shan, Richard A. Flavell Siyuan Ding, Ningguo Feng, Harry B. Greenberg Siyuan Ding, Harry B. Greenberg Penghua Wang, Yujiao Zhao Wen Pan, Jun Lu Jun Zhao, Yuval Kluger Kellie A. Jurado, Clara Abraham, Erol Fikrig Erol Fikrig, Richard A. Flavell | 2017 | 现代生物医学进展2017，17，27： | 10 |
| 6 | Complex networks theory for analyzing metabolic networks显示文摘One of the main tasks of post-genomic informatics is to systematically investigate all mole- cules and their interactions within a living cell so as to understand how these molecules and the interactions between them relate to the function of the organism, while networks are appropriate abstract description of all kinds of interactions. In the past few years, great achievement has been made in developing theory of complex networks for revealing the organizing prin- ciples that govern the formation and evolution of various complex biological, technological and social networks. This paper reviews the accomplishments in constructing genome-based metabolic networks and describes how the theory of complex networks is applied to analyze metabolic networks. | ZHAO Jing YU Hong LUO Jianhua CAO Z. W. LI Yixue | 2006 | Chinese Science Bulletin2006，51，13： | 10 |
| 7 | JWA is required for arsenic trioxide induced apoptosis in HeLa and MCF-7 cells via reactive oxygen species and mitochondria linked signal pathway显示文摘 | Zhou, J. H. Ye, J. Zhao, X. J. Li, A. P. Zhou, J. W. | 2008 | 南京医科大学学报(自然科学版)2008，28，12： | 8 |
| 8 | Evaluation of combination gene therapy with PTEN and antisense hTERT for malignant glioma in vitro and xenografts显示文摘 | You, Y. P. Geng, X. Z. Zhao, P. FU, Z. Wang, C. Z. Chao, S. W. Liu, N. Lu, A. L. Gardner, K. Pu, P. Y. Kong, C. S. Ge, Y. Judge, S. I. V. Li, Q. D. Q | 2007 | 南京医科大学学报(自然科学版)2007，27，5： | 6 |
| 9 | pH modeling for maximum dissolved organic matter removal by enhanced coagulation显示文摘Correlations between raw water characteristics and pH after enhanced coagulation to maximize dissolved organic matter(DOM) removal using four typical coagulants(FeCl3,Al2(SO4)3,polyaluminum chloride(PACl) and high performance polyaluminum chloride(HPAC)) without pH control were investigated.These correlations were analyzed on the basis of the raw water quality and the chemical and physical fractionations of DOM of thirteen Chinese source waters over three seasons.It was found that the final pH after enhanced coagulation for each of the four coagulants was in?uenced by the content of removable DOM(i.e.hydrophobic and higher apparent molecular weight(AMW) DOM),the alkalinity and the initial pH of raw water.A set of feed-forward semi-empirical models relating the final pH after enhanced coagulation for each of the four coagulants with the raw water characteristics were developed and optimized based on correlation analysis.The established models were preliminarily validated for prediction purposes,and it was found that the deviation between the predicted data and actual data was low.This result demonstrated the potential for the application of these models in practical operation of drinking water treatment plants. | Jiankun Xie Dongsheng Wang John van Leeuwen Yanmei Zhao Linan Xing Christopher W. K. Chow | 2012 | Journal of Environmental Sciences2012，24，2： | 5 |
| 10 | OPTION PRIORITIZATION FOR UNKNOWN PREFERENCE显示文摘一种选择 prioritization 技术被开发高效地得到偏爱,未知、松脆,在战略冲突的决定制造者(数据管理系统) 。在为冲突分辨率的图模型,每 DM 有至少一种选择,其各个可以被选择。一种州,或可能的情形,当时,被形成所有数据管理系统做一种选择选择。软件 GMCR II 包含使让 modeller 进入用描述数据管理系统的按优先级排列的陈述在州上订的数据管理系统松脆的偏爱容易的一个选择 prioritization 过程比较喜欢的选择联合。这个过程被增加二新逻辑 connectives 扩大描述偏爱的无常。为每 DM,为各可行的状态的可能的分数的一个范围当时能是计算的,便于订的偏爱的决心由比较并且评价分数包含无常。为了表明这新方法论怎么能习惯于,处于一个真实世界的决定问题代表未知偏爱,它在建议的水出口上被用于加拿大的争论。 | Jing Yu Keith W. Hipel D. Marc Kilgour Min Zhao | 2016 | Journal of Systems Science and Systems Engineering2016，25，1： | 5 |
| 11 | A sperm GPI-anchored protein elicits sperm-cumulus cross-talk leading to the acrosome reaction显示文摘 | Yin, L. Chung, C. M. Huo, R. Liu, H. Zhou, C. Xu, W. Zhu, H. Zhang, J. Shi, Q. Wong, H. Y.C. Chen, J. Lu, Y. Bi, Y. Zhao, C. Du, Y. Ma, M. Cai, Y. Chen, W. Y. Fok, K. L. Tsang, L. L. Li, K. Ni, Y. Chung, Y. W. Zhou, Z. Sha, J. Chan, H. C. | 2009 | 南京医科大学学报(自然科学版)2009，29，4： | 5 |
| 12 | Face recognition显示文摘 | W. Zhao R. Chellappa P. J. Phillips A. Rosenfeld | 2003 | ACM Computing Surveys (CSUR)2003，，4： | 5 |
| 13 | Effects of PI3-k/Akt short hairpin RNA on proliferation, fibronectin production and synthesis of thrombospondin-1 and transforming growth factor-beta(1 ) in glomerular mesangial cells induced by sublytic C5b-9 complexes显示文摘 | Gao, L. Zhang, Y. Qiu, W. Xu, W. Feng, X. Ren, J. Jiang, X. Wang, H. Zhao, D. Wang, Y. | 2009 | 南京医科大学学报(自然科学版)2009，29，3： | 5 |
| 14 | 半导体物理研究的回顾与展望显示文摘半导体物理是凝聚态物理领域中的一个活跃分支 ,也是半导体科学技术发展的重要物理基础 .半个多世纪以来 ,半导体物理自身不仅在晶态半导体、非晶态半导体、半导体表面、半导体超晶格、纳米半导体和有机半导体等领域中都获得了令世人瞩目的重大进展 ,而且它还是一系列新材料、新结构、新效应、新器件和新工艺产生的源泉 ,极大地丰富了凝聚态物理的研究内容和有力地促进了半导体科学技术的迅速发展 .温故而知新 .今天 ,我们重新认识它的发展规律与特点 ,对于把握半导体物理在 2 1世纪的发展走向具有直接的现实指导意义 . | 彭英才 X. W. Zhao 傅广生 | 2004 | 自然杂志2004，26，6： | 4 |
| 15 | Numerical simulation of blood flow and interstitial fluid pressure in solid tumor microcirculation based on tumor-induced angiogenesis显示文摘A coupled intravascular transvascular 空隙的液体流动模型被开发在稳固的肿瘤学习血流动和空隙的液体压力的分布微循环基于一个导致肿瘤的微脉管的网络。这从 2D 被产生肿瘤 angiogenesis 的九点的分离数学模型并且包含二个父母容器。通过微脉管的网络的血流动和在肿瘤纸巾的空隙的液体流动被扩大 Poiseuille 的法律和 Darcy 的法律执行分别地, transvascular 流动被欧椋鸟的法律描述;脉管的渗透和空隙的水力的传导性的效果也被考虑。模拟结果在肿瘤的里面上预言异构的血供应,空隙的高血压和低传送对流,它与生理的观察事实一致。这些结果可以为肿瘤和进一步临床的研究的 anti-angiogenesis 处理提供有益的信息。 | Gaiping Zhao Jie Wu Shixiong Xu M. W. Collins Quan Long Carola S. Konig Yuping Jiang Jian Wang A. R. Padhani | 2007 | Acta Mechanica Sinica2007，23，5： | 4 |
| 16 | High Prevalence of Sessile Serrated Adenomas With BRAF Mutations: A Prospective Study of Patients Undergoing Colonoscopy显示文摘 | Kevin J. Spring Zhen Zhen Zhao Rozemary Karamatic Michael D. Walsh Vicki L.J. Whitehall Tanya Pike Lisa A. Simms Joanne Young Michael James Grant W. Montgomery Mark Appleyard David Hewett Kazutomo Togashi Jeremy R. Jass Barbara A. Leggett | 2006 | Gastroenterology2006，，5： | 3 |
| 17 | Improvements to a MODIS global terrestrial evapotranspiration algorithm显示文摘 | Qiaozhen Mu Maosheng Zhao Steven W. Running | 2011 | Remote Sensing of Environment2011，，8： | 3 |
| 18 | Development of a global evapotranspiration algorithm based on MODIS and global meteorology data显示文摘 | Qiaozhen Mu Faith Ann Heinsch Maosheng Zhao Steven W. Running | 2007 | Remote Sensing of Environment2007，，4： | 2 |
| 19 | Utilization of metabolomics to identify serum biomarkers for hepatocellular carcinoma in patients with liver cirrhosis显示文摘 | Habtom W. Ressom Jun Feng Xiao Leepika Tuli Rency S. Varghese Bin Zhou Tsung-Heng Tsai Mohammad R. Nezami Ranjbar Yi Zhao Jinlian Wang Cristina Di Poto Amrita K. Cheema Mahlet G. Tadesse Radoslav Goldman Kirti Shetty | 2012 | Analytica Chimica Acta2012，，： | 2 |
| 20 | 气相法制备ZnO纳米线及其阵列的生长机制显示文摘半导体纳米线和纳米棒及其阵列是具有强量子限制效应的一维纳米结构,它们所具有的新颖光学、电学、磁学和力学性质,使其在发光器件、场效应器件、存储器件和传感器件及其集成技术中具有潜在的应用。本文以生长机制为主线,简要介绍了气相法,即采用金属催化剂的气-液-固(VLS)法和不采用金属催化剂的气-固(VS)法,在ZnO纳米线及其阵列结构制备中的应用,评论了近3~5年内它们在这一领域研究中取得的研究进展。讨论了目前存在的问题,并预测了今后的发展趋势。 | 彭英才 X. W. Zhao | 2008 | 人工晶体学报2008，37，2： | 2 |
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