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| 1 | HIF-1: structure, biology and natural modulators显示文摘Hypoxia-inducible factor 1(HIF-1),as a main transcriptional regulator of metabolic adaptation to changes in the oxygen environment,participates in many physiological and pathological processes in the body,and is closely related to the pathogenesis of many diseases.This review outlines the mechanisms of HIF-1 activation,its signaling pathways,natural inhibitors,and its roles in diseases.This article can provide new insights in the diagnosis and treatment of human diseases,and recent progress on the development of HIF-1 inhibitors. | YANG Chao ZHONG Zhang-Feng WANG Sheng-Peng VONG Chi-Teng YU Bin WANG Yi-Tao | 2021 | Chinese Journal of Natural Medicines2021，19，7： | 14 |
| 2 | Ignition Pattern Analysis for Automotive Engine Trouble Diagnosis Using Wavelet Packet Transform and Support Vector Machines显示文摘Engine spark ignition is an important source for diagnosis of engine faults.Based on the waveform of the ignition pattern,a mechanic can guess what may be the potential malfunctioning parts of an engine with his/her experience and handbooks.However,this manual diagnostic method is imprecise because many spark ignition patterns are very similar.Therefore,a diagnosis needs many trials to identify the malfunctioning parts.Meanwhile the mechanic needs to disassemble and assemble the engine parts for verification.To tackle this problem,an intelligent diagnosis system was established based on ignition patterns.First,the captured patterns were normalized and compressed.Then wavelet packet transform(WPT) was employed to extract the representative features of the ignition patterns.Finally,a classification system was constructed by using multi-class support vector machines(SVM) and the extracted features.The classification system can intelligently classify the most likely engine fault so as to reduce the number of diagnosis trials.Experimental results show that SVM produces higher diagnosis accuracy than the traditional multilayer feedforward neural network.This is the first trial on the combination of WPT and SVM to analyze ignition patterns and diagnose automotive engines. | VONG Chi-man WONG Pak-kin TAM Lap-mou ZHANG Zaiyong | 2011 | Chinese Journal of Mechanical Engineering2011，24，5： | 10 |
| 3 | Challenges and needs for China to eliminate rabies显示文摘In China,rabies is a significant public health concern where dogs remain the main reservoir of disease transmission to humans;rabies-related mortality ranks second in the world.We compiled all published articles and official documents on rabies in China's Mainland to examine challenges and needs to eliminate rabies in the country.The Chinese authorities have identified rabies as a priority,recognized rabies control in dogs as key to control rabies in humans and required intersectoral collaborations.Efforts have been made to respond effectively to the latest re-emergence of rabies,which peaked in 2007 with>3,300 cases.Despite these outcomes and the increasing volume of publications and regulations in the recent years,our review points to some major information gaps to improve rabies control activities and envisage elimination program.An emphasis on laboratory or pathogen-associated and basic epidemiology research in the literature has contrasted with the absence of information to monitor various systems in humans and animals(e.g.quality of surveillance,response and post-exposure prophylaxis).Information is also lacking to appropriately inform policymakers(e.g.economic disease burden,impact of policies)and assist program managers(e.g.comprehensive and strategic guidance for cost-effective prevention and control activities,public education and dog population management).In conclusion,strategic planning is needed to provide a sense of direction,demonstrate feasibility of elimination in China,and develop a research agenda,addressing country’s operational needs and constraints.The planning should be a multisectoral effort. | Wenwu Yin Jie Dong Changchun Tu John Edwards Fusheng Guo Hang Zhou Hongjie Yu Sirenda Vong | 2013 | Infectious Diseases of Poverty2013，2，1： | 3 |
| 4 | Compact Finite Difference Scheme for the Fourth-Order Fractional Subdiffusion System显示文摘In this paper,we study a high-order compact difference scheme for the fourth-order fractional subdiffusion system.We consider the situation in which the unknown function and its first-order derivative are given at the boundary.The scheme is shown to have high order convergence.Numerical examples are given to verify the theoretical results. | Seakweng Vong Zhibo Wang | 2014 | Advances in Applied Mathematics and Mechanics2014，6，4： | 2 |
| 5 | Proton Pump Inhibitors Exacerbate NSAID-Induced Small Intestinal Injury by Inducing Dysbiosis显示文摘 | John L. Wallace Stephanie Syer Emmanuel Denou Giada de Palma Linda Vong Webb McKnight Jennifer Jury Manlio Bolla Premysl Bercik Stephen M. Collins Elena Verdu Ennio Ongini | 2011 | Gastroenterology2011，，： | 2 |
| 6 | Chemical modification of silica gels 显示文摘 | VONG M S W BAZIN N SERMON P A | 1997 | J Sol Gel Sci Technol1997，8，： | 1 |
| 7 | Endogenous andexogenous hydrogen, sulfide promotes resolution of colitisin rats 显示文摘 | Wallace JL Vong L McKnight W | 2009 | Gastroenterology2009，2009，2： | 1 |
| 8 | Rate-dependent hysteresis modeling and control of a piezostage using online support vector machine and relevance vector machine 显示文摘 | WONG P K XU Q S VONG C M WONG H C | 2012 | IEEE Transactions on Industrial Electronics2012，59，4： | 1 |
| 9 | A novel route for the preparation of dimeric tetraorganodistannoxanes 显示文摘 | JENS B DAINIS D VONG S K | 2002 | J Organomet Chem2002，659，： | 1 |
| 10 | A new framework of simultaneous-fauh diagnosis using pairwise probabilistic multi-label classification for time- dependent modes显示文摘 | VONG C M WONG P K IP W F | 2013 | IEEE Transaction on Industrial Electronics2013，60，8： | 1 |
| 11 | Prediction of automotive engine power and torque using least squares support vector machines and Bayesian inference显示文摘 | Vong Chi-man Wong Pak-kin Li Yi-ping | 2006 | Engineering Applications of Artificial Intelligence2006，19，3： | 1 |
| 12 | In situ gelling of algi nate / pluronic solutions for opthalmic delivery of pilo carpine显示文摘 | Lin HR Sung KC Vong WJ | 2004 | Biomaeromolecules2004，5，23： | 1 |
| 13 | Rate-dependent hystere- sis modeling and control of a piezostage using online support vector machine and relevance vector machine 显示文摘 | PAK-KIN W XU Q S VONG C M | 2012 | IEEE Transactions on In- dustrial Electronics2012，59，4： | 1 |
| 14 | Endogenous and exogenous hydrogen sulfide promotes resolution of colotos in rats显示文摘 | Wallace J L Vong L McKnight W | 2009 | Gastroenterology2009，137，2： | 1 |
| 15 | Prediction minority class for suspended particulate matters level by extreme learn- ing machine 显示文摘 | VONG C-M IP W-F WONG P-K | 2014 | Neurocomputing2014，128，： | 1 |
| 16 | Genetic diversity and lineage dynamic of dengue virus serotype 1 (DENV-1) in Cambodia显示文摘 | Veasna Duong Cameron Simmons Laurent Gavotte Alain Viari Sivuth Ong Ngan Chantha Niall J. Lennon Bruce W. Birren Sirenda Vong Jeremy J. Farrar Matthew R. Henn Vincent Deubel Roger Frutos Philippe Buchy | 2013 | Infection, Genetics and Evolution2013，，： | 1 |
| 17 | Case-based Reasoning and Adaptation in Hydraulic Production Machine Design显示文摘 | Vong C M Leungb T P Wong P K | 2002 | Engineering Applications of Artificial Intelligence2002，15，： | 1 |
| 18 | Real-time fault diagnosis for gas turbine generator systems using extreme learning machine 显示文摘 | Wong P K Yang Z Vong C M | 2013 | Neurocomputing2013，128，3： | 1 |
| 19 | Immobilization and mobilization of labelled sulphur in relation to soil arylsulphatase activity in rhizosphere soil of field-grown rape, barley and fallow 显示文摘 | Vong P C Dedourge O Guckert A | 2004 | Plant Soil2004，258，： | 1 |
| 20 | Generation of conditional Mef2cloxP/loxP mice for temporal- and tissue-specific analyses显示文摘 | Vong LH Ragusa M J Schwarz JJ | 2005 | Genesis2005，43，1： | 1 |
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