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| 1 | Performance of the Montreal classification for inflammatory bowel diseases显示文摘AIM:To validate the Montreal classification system for Crohn's disease(CD) and ulcerative colitis(UC) within the Netherlands.METHODS:A selection of 20 de-identified medical records with an appropriate representation of the inflammatory bowel disease(IBD) sub phenotypes were scored by 30 observers with different professions(gastroenterologist specialist in IBD,gastroenterologist in training and IBD-nurses) and experience level with IBD patient care.Patients were classified according to the Montreal classification.In addition,participants were asked to score extra-intestinal manifestations(EIM) and disease severity in CD based on their clinical judgment.The inter-observer agreement was calculated by percentages of correct answers(answers identical to the 'expert evaluation') and Fleiss-kappa(k).Kappa cutoffs:< 0.4-poor; 0.41-0.6-moderate; 0.61-0.8-good; > 0.8 excellent.RESULTS:The inter-observer agreement was excellent for diagnosis(k = 0.96),perianal disease(k = 0.92) and disease location in CD(k = 0.82) and good for age of onset(k = 0.67),upper gastrointestinal disease(k = 0.62),disease behaviour in CD(k = 0.79) and disease extent in UC(k = 0.65).Disease severity in UC was scored poor(k = 0.23).The additional items resulted in a good inter-observer agreement for EIM(k = 0.68) and a moderate agreement for disease severity in CD(k = 0.44).Percentages of correct answers over all Montreal items give a good reflection of the inter-observer agreement(> 80%),except for disease severity(48%-74%).IBD-nurses were significantly worse in scoring upper gastrointestinal disease in CD compared to gastroenterologists(P = 0.008) and gastroenterologists in training(P = 0.040).Observers with less than 10 years of experience were significantly better at scoring UC severity than observers with 10-20 years(P = 0.003) and more than 20 years(P = 0.003) of experience with IBD patient care.Observers with 10-20 years of experience with IBD patient care were significantly better at scoring upper gastrointestinal disease in CD than observers with less than 10 years(P = 0.007) and more than 20 years(P = 0.007) of experience with IBD patient care.CONCLUSION:We found a good to excellent interobserver agreement for all Montreal items except for disease severity in UC(poor). | Lieke M Spekhorst Marijn C Visschedijk Rudi Alberts Eleonora A Festen Egbert-Jan van der Wouden Gerard Dijkstra Rinse K Weersma | 2014 | World Journal of Gastroenterology2014，20，41： | 4 |
| 2 | Emissions of persistent organic pollutants and eight candidate POPs from UNECE–Europe in 2000, 2010 and 2020 and the emission reduction resulting from the implementation of the UNECE POP protocol显示文摘 | Hugo Denier van der Gon Maarten van het Bolscher Antoon Visschedijk Peter Zandveld | 2007 | Atmospheric Environment2007，，40： | 1 |
| 3 | Incubation of chicken eggs at altitude:Theoretical consideration of optimal gas composition显示文摘 | Visschedijk A H J Rahn H | 1981 | Bri Poult Sci1981，22，5： | 1 |
| 4 | Incubation of chicken eggs at altitude, theoretical consideration of optimal gas composition 显示文摘 | Visschedijk A H J Rahn H | 1981 | British Poultry Science1981，22，： | 1 |
| 5 | Fear of falling in patients with hip fractures:prevalence and related psychological factors显示文摘 | Visschedijk J van Balen R Hertogh C | 2014 | J Am Med Dir Assoc2014，14，3： | 1 |
| 6 | Emissions of persistent organic pollutants and eight candidate POPs from UNECE-Europe in 2000,2010 and2020 and the emission reduction resulting from the implementation of the UNECE POP protocol显示文摘 | Denier Van Der Gon H Van Het Bolscher M Visschedijk A | 2007 | Atmos Environ2007，41，40： | 1 |
| 7 | Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohn' s disease 显示文摘 | Fransen K Visschedijk M C van Sommeren S | 2010 | Hum Mol Genet2010，19，17： | 1 |
| 8 | Incubation of chicken eggs at altitude: Theoretical consideration of optimalgas composition 显示文摘 | Visschedijk A H J Rahn H | 1981 | British Poult Sci1981，22，： | 1 |
| 9 | Altitude hypocapnia at 2800m does not affect development of the chicken embryo 显示文摘 | Girard H Visschedijk A H J | 1987 | J Exp Zool1987，1，： | 1 |
| 10 | Gas exchange and hatchability of chicken eggs incubated at simulated high altitude 显示文摘 | Visschedijk A H J | 1985 | J Appl Physiol1985，58，2： | 1 |
| 11 | Physics and physiology of incubation显示文摘 | Visschedijk A H J | 1991 | Brit Poultry Sci1991，32，： | 1 |
| 12 | Fear of falling in patients with hip fractures:prevalence and related psychological factors显示文摘 | Visschedijk J van Balen R Hertogh C | 2013 | J Am MedDirAssoc2013，14，3： | 1 |
| 13 | Gas exchange and hatchability of chicken eggs incubated at simulated high altitude 显示文摘 | Visschedijk A H J | 1985 | J Applied Physiol1985，58，： | 1 |
| 14 | Emissions of persistent organic pollutants and eight candidate POPs from UNECE-Europe in 2000,2010 and 2020 and the emission reduction resulting from the implementation of the UNECE POP protocol显示文摘 | DENIER VAN DER GON H VAN HET BOLSCHER M VISSCHEDIJK A | 2007 | Atmos Environ2007，41，40： | 1 |
| 15 | Incubation of chicken eggs at altitude theoretical consideration of optimal gas composition 显示文摘 | Visschedijk A H J Rahn H | 1981 | British Poultry Science1981，22，5： | 1 |
| 16 | Gas exchange and hatchability of chicken eggs incubated at simulated high altitude显示文摘 | Visschedijk A H J | 1985 | J Appl Physiol1985，58，： | 1 |
| 17 | Gas exchange and hatchability of chicken eggs incubated at simulated high altitude显示文摘 | Visschedijk A H J | 1985 | J Appl Physiol1985，58，： | 1 |
| 18 | HNF4α and CDH1 Are Associated with Ulcerative Colitis in a Dutch Cohort显示文摘 | Van Sommeren S Visschedijk M C Festen E A | 2011 | Inflamm Bowel Dis2011，17，8： | 1 |
| 19 | HNF4alpha and CDH1 are associated with ulcerative colitis in a Dutch cohort 显示文摘 | Van SS Visschedijk MC Festen EA | 2010 | Inflamm Bowel Dis2010，，： | 1 |
| 20 | Fear of falling after hip fracture in vulnerable older persons rehabilitating in a skiled nursing facility显示文摘 | Visschedijk JHM Caljouw MAA VanBalen R | 2014 | J Rehabil Med2014，46，3： | 1 |
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