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| 1 | Lepidium meyenii (Maca) improved semen parameters in adult men显示文摘Aim: The present study was designed to determine the effect of a 4-month oral treatment with tablets of Lepidium meyenii (Maca) on seminal analysis in nine adult normal men aged 24 - 44 years old. Methods: Nine men received tablets of Maca (1500 or 3000 mg/day) for 4 months. Seminal analysis was performed according to guidelines of the World Health Organization (WHO). Serum luteinizing hormone (LH), follicle stimulating hormone (FSH), prolactin (PRL), testosterone (T) and estradiol (E2) were measured before and after treatment. Results: Treatment with Maca resulted in increased seminal volume, sperm count per ejaculum, motile sperm count, and sperm motility. Serum hormone levels were not modified with Maca treatment. Increase of sperm count was not related to dose of Maca.Conclusion: Maca improved sperm production and sperm motility by mechanisms not related to LH, FSH, PRL, T and E2 . | Gustavo F.Gonzales Amanda Cordova Carla Gonzales Arturo Chung Karla Vega Arturo Villena | 2001 | Asian Journal of Andrology2001，3，4： | 23 |
| 2 | Interferences of commercial NO<sub>2</sub> instruments in the urban atmosphere and in a smog chamber显示文摘 | Villena G. Bejan I. Kurtenbach R. Wiesen P. Kleffmann J | 2012 | Atmospheric Measurement Techniques2012，，29： | 2 |
| 3 | Non-alcoholic fatty liver disease in patients with intestinal, pulmonary or skin diseases: Inflammatory cross-talk that needs a multidisciplinary approach显示文摘Non-alcoholic fatty liver disease(NAFLD)is currently considered the most common cause of liver disease.Its prevalence is increasing in parallel with the obesity and type 2 diabetes mellitus(DM2)epidemics in developed countries.Several recent studies have suggested that NAFLD may be the hepatic manifestation of a systemic inflammatory metabolic disease that also affects other organs,such as intestine,lungs,skin and vascular endothelium.It appears that local and systemic proinflammatory/anti-inflammatory cytokine imbalance,together with insulin resistance and changes in the intestinal microbiota,are pathogenic mechanisms shared by NAFLD and other comorbidities.NAFLD is more common in patients with extrahepatic diseases such as inflammatory bowel disease(IBD),obstructive syndrome apnea(OSA)and psoriasis than in the general population.Furthermore,there is evidence that this association has a negative impact on the severity of liver lesions.Specific risk characteristics for NAFLD have been identified in populations with IBD(i.e.age,obesity,DM2,previous bowel surgery,IBD evolution time,methotrexate treatment),OSA(i.e.obesity,DM2,OSA severity,increased transaminases)and psoriasis(i.e.age,metabolic factors,severe psoriasis,arthropathy,elevated transaminases,methotrexate treatment).These specific phenotypes might be used by gastroenterologists,pneumologists and dermatologists to create screening algorithms for NAFLD.Such algorithms should include non-invasive markers of fibrosis used in NAFLD to select subjects for referral to the hepatologist.Prospective,controlled studies in NAFLD patients with extrahepatic comorbidities are required to demonstrate a causal relationship and also that appropriate multidisciplinary management improves these patients’prognosis and survival. | Mercedes Perez-Carreras Begoña Casis-Herce Raquel Rivera Inmaculada Fernandez Pilar Martinez-Montiel Victoria Villena | 2021 | World Journal of Gastroenterology2021，27，41： | 2 |
| 4 | Quantitative age-related changes in dorsal lateral geniculate nucleus rdlay neurons of the rat显示文摘 | VIDAL L RUIZ C VILLENA A | 2004 | Neuroscience esearch2004，48，： | 1 |
| 5 | Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor -1 (Pref-1) 显示文摘 | Lee K Villena JA Moon YS | 2003 | J Clin Invest2003，111，： | 1 |
| 6 | The Dark Side of Buyer-Supplier Relationships: A Social Capital Perspective 显示文摘 | Villena V H Revilla E Choi T Y | 2011 | Journal of Operations Management2011，29，6： | 1 |
| 7 | Knowledge integration taxonomy in buyer-supplier relationships: Trade-offs between efficiency and innovation 显示文摘 | Revilla E and Villena V H | 2012 | International Journal of Production Eco-nomics2012，140，2： | 1 |
| 8 | Pharmacodynamic tri- al ofnimomzumab in imresectable squamous cell carcino- ma of the head and neck: a SENDO foundation study显示文摘 | Rojo F Gracias E Villena N | 2010 | Clin Cancer Res2010，16，8： | 1 |
| 9 | HLA allele and haplotype frequencies in Algerians;relatedness to Spaniards and Basques显示文摘 | Villena A Benmamar D | 1995 | Human Immunology1995，43，： | 1 |
| 10 | Regulation of brush-border enzyme activities and enterocyte migration rates in mouse small intestine 显示文摘 | Ferraris R P Villenas S A Diamond J | 1992 | American Journal of Physiology1992，262，6： | 1 |
| 11 | The dark side of buyer-supplier relationships:A social capital perspective显示文摘 | Villena V H Revilla E Choi T Y | | 0，，06： | 1 |
| 12 | Treatment of toxoplasmosis during pregnancy: a multicenter study of impact on fetal transmission and children's sequelae at age 1 year显示文摘 | Foulon W Villena I Stray-Pedersen B | 1999 | Am J Obstet Gynecol1999，180，： | 1 |
| 13 | β-Glucosidase activity in wine yeasts:application in enology显示文摘 | Villena M Iranzo J Perez A | 2007 | Enzyme and Microbial Technology2007，40，3： | 1 |
| 14 | Midline diastema and fre- num morphology in the primary dentition 显示文摘 | Diaz-Pizan ME Lagravere MO Villena R | 2006 | J Dent Child (Chic)2006，73，1： | 1 |
| 15 | Thyroid hormone levels improve the prediction of mortality among patients admitted to the intensive care unit显示文摘 | Chinga-Alayo E Villena J Evans AT | 2005 | Int Care Med2005，31，10： | 1 |
| 16 | Desnutrin,an adipocyte gene encoding a novel patatin domain-containing protein,is induced by fasting and glucocorticoids:ectopic expression of desnutrin increases triglyceride hydrolysis显示文摘 | Villena J A Roy S Sarkadi-Nagy E | 2004 | J Biol Chem2004，279，47： | 1 |
| 17 | Recombinant antigens to detect Toxoplasma gondii-specific immunoglobulin G and immunoglobulin M in human sera by enzyme immunoassay 显示文摘 | Aubert D Maine GT Villena I | 2000 | J Clin Microbiol2000，38，3： | 1 |
| 18 | Induced adiposity and adipoeyte hypertrophy in mice lacking the AMP-activated protein kinase-alpha2 subunit 显示文摘 | Villena JA Viollet B Andreelli F Kahn A Vaulont S Sul HS | 2004 | Diabetes2004，53，9： | 1 |
| 19 | Behavior of an Aeromonas hydrophila aroa live vaccine in water microcosms显示文摘 | Vivas J Carracedo B Riano J Razquin B E Lopez- Fierro P Acosta F Naharro G Villena A J | 2004 | AppL Environ Microbiol2004，70，5： | 1 |
| 20 | Capsular polyzaccharides galactoxylomannan and glucaronoxylomannan from Cryptococcus neoformans induce macrophage apoptesis mediated by Fas ligand显示文摘 | Villena SN Pinheiro BO Pinheiro CS | 2008 | Cell Microbiol2008，10，6： | 1 |
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