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| 1 | Stool-based DNA testing,a new noninvasive method for colorectal cancer screening,the first report from Iran显示文摘AIM:To detect tumor-associated DNA changes in stool samples among Iranian patients with colorectal cancer(CRC)compared to healthy individuals using BAT-26,p16 hypermethylation and long DNA markers.METHODS:Stool DNA was isolated from 45 subjects including 25 CRC patients and 20 healthy individuals using a new,fast and easy extraction method.Long DNA associated with tumor was detected using polymerase chain reaction method.Microsatellite studies were performed utilizing denaturating polyacrylamide gel to determine the instability of BAT-26.Methylation status of p16 promoter was analyzed using methylation-specific PCR(MSP).RESULTS:The results showed a significant difference in existence of long DNA(16 in patients vs 1 in controls,P < 0.001)and p16(5 in patients vs none in controls,P = 0.043)in the stool samples of two groups.Long DNA was detected in 64% of CRC patients;whereas just one of the healthy individuals was positive for Long DNA.p16 methylation was found in 20% of patients and in none of healthy individuals.Instability of BAT-26 was not detected in any of stool samples.CONCLUSION:We could detect colorectal cancer related genetic alterations by analyzing stool DNA witha sensitivity of 64% and 20% and a specificity of 95% and 100% for Long DNA and p16 respectively.A non-invasive molecular stool-based DNA testing can provide a screening strategy in high-risk individuals.However,additional testing on more samples is necessary from Iranian subjects to determine the exact specificity and sensitivity of these markers. | Mohammad Reza Abbaszadegan Alireza Tavasoli Arash Velayati Hamid Reza Sima Hassan Vosooghinia Mehdi Farzadnia Hamid Asadzedeh Mehran Gholamin Ezzat Dadkhah Azadeh Aarabi | 2007 | World Journal of Gastroenterology2007，13，10： | 14 |
| 2 | 胶质气体泡沫基泡沫水泥体系显示文摘为了解决常规泡沫水泥存在的密度高、泡沫不稳定、抗压强度低、孔隙度高、有效期短等缺点,研发了一种新型的胶质气体泡沫(CGA)基泡沫水泥体系并进行性能评价。将CGA作为泡沫组分加入基浆,从优化粒度分布的角度考虑加入空心球和微硅石继续优化配方。通过孔隙度、渗透率、强度、脆性、弹性、自由水含量、泡沫稳定性和密度测试等评价CGA基泡沫水泥体系性能,实验结果表明:泡沫占比为10%时,水泥密度降到1040 kg/m3;水泥体系中形成了稳定的微泡网络结构且不受高温高压影响;最优CGA基泡沫水泥自由水含量为零,孔隙度为24%,渗透率为0.7×103μm^2,弹性模量低、泊松比高,抗压强度合理,表现出韧性特征,具有更强的弹性和柔性,可承受区域地应力。 | VELAYATI Arian ROOSTAEI Morteza RASOOLIMANESH Rasool SOLEYMANI Mohammad FATTAHPOUR Vahidoddin | 2019 | 石油勘探与开发2019，46，6： | 3 |
| 3 | Protective effect of N-acetylcysteine on antituberculosis drug-induced hepatotoxicity显示文摘 | Shadi Baniasadi Parivash Eftekhari Payam Tabarsi Fanak Fahimi Mohammad Reza Raoufy Mohammad Reza Masjedi Ali Akbar Velayati | 2010 | European Journal of Gastroenterology & Hepatology2010，，10： | 2 |
| 4 | Risk factors for human brucellosis in Iran: a case–control study显示文摘 | Masomeh Sofian Arezoo Aghakhani Ali Akbar Velayati Mohammad Banifazl Ali Eslamifar Amitis Ramezani | 2007 | International Journal of Infectious Diseases2007，，： | 1 |
| 5 | Microembolic signals in subarachnoid hemorrhage显示文摘 | Azarpazhooh MR Velayati A Chambers BR | 2009 | J Clin Neurosci2009，16，： | 1 |
| 6 | Possible transmission of hepatitis B virus between spouses and their children in Babol, Northern Iran显示文摘 | ROUSHAN M R MOHRAZ M VELAYATI A A | 2007 | Tropical Doctor2007，37，4： | 1 |
| 7 | AlpHA-synuclein interacts with glucocerebrosidase providing a molecular link between Parkinson and Gaucher diseases显示文摘 | Yap TL Grusehus JM Velayati A | 2011 | J Biol Chem2011，286，28： | 1 |
| 8 | Emergence of new forms of totally drug-resistant tuberculosis bacilli:super extensively drug-resistant tuberculosis or totally drug-resistant strains in Iran显示文摘 | Velayati AA Masjedi MR Farnia P | 2009 | Chest2009，136，2： | 1 |
| 9 | False-positive results using a Gaucher diagnostic kit--RecTL and N370S 显示文摘 | Choi JH Velayati A Stubblefield BK | 2010 | Mol Genet Metab2010，100，1： | 1 |
| 10 | Recurrence aftertreatmentsuccess in pulmonary multidrug-resistant tuber-culosis:predication by continual PCR positivity显示文摘 | Velayati A A Farnia P? Masjedi M R | 2012 | Int JClin Exp Med2012，5，3： | 1 |
| 11 | A mutation in SCARB2 is a modifier in Gaucher disease显示文摘 | Velayati A DePaolo J Gupta N | 2011 | Hum Murat2011，32，11： | 1 |
| 12 | Risk factors for human brucellosis in Iran:a case-control study显示文摘 | Sofian M Aghakhani A Velayati AA | 2008 | Int J Infect Dis2008，12，2： | 1 |
| 13 | Coinheritance of Gaucher disease and α-thalassemia resulting in confusion between two inherited hematologic diseases显示文摘 | Miri-Moghaddam E Velayati A Naderi M | 2011 | Blood CellsMolDis2011，46，1： | 1 |
| 14 | The totally drug resistant tu-berculosis(TDR-TB)显示文摘 | Velayati AA Farnia P Masjedi MR | | 0，，04： | 1 |
| 15 | Persistence of hepatitis B vaccine immunity in hemodialysis patients显示文摘 | Ramezani A Velayati AA Eslamifar A | 2008 | Ther Apher Dial2008，12，2： | 1 |
| 16 | Microembolic signals in subaraehnoid hemorrhage显示文摘 | Azarpazhooh MR Velayati A Chambers BR | 2009 | Journal of Clinical Neuroscience2009，16，： | 1 |
| 17 | Interaction of Pattern Recognition Receptors with Mycobacterium Tuberculosis显示文摘 | Esmaeil Mortaz Ian M. Adcock Payam Tabarsi Mohammad Reza Masjedi Davood Mansouri Ali Akbar Velayati Jean-Laurent Casanova Peter J. Barnes | 2015 | Journal of Clinical Immunology2015，，1： | 1 |
| 18 | The role of glucocerebrosidase mutations in Parkinson disease and Lewy body disorders 显示文摘 | Velayati A Yu WH Sidransky E | 2010 | Curr Neurol Neurosci Rep2010，10，3： | 1 |
| 19 | Nontuberculous mycobacteria isolation from clinical and environmental samples in Iran: twenty years of surveillance显示文摘 | Velayati AA Farnia P Mozafari M | 2015 | Biomed Res Int2015，2015，25： | 1 |
| 20 | High prevalence of ri- fampin-monoresistant tuberculosis: a retrospective analysis among Iranian pulmonary tuberculosis patients显示文摘 | Velayati AA Farnia P Mozafari M | 2014 | AM J Trop Med Hyg2014，90，1： | 1 |
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