维普期刊资源整合服务平台（V6.5）

维普中文期刊产品整合服务

8篇 您的检索式：作者名="Unrean"

选中清除导出查看参考文献查看引证文献引用追踪共1页首页上一页第1页下一页末页 /1 跳转

		题名	作者	年代	出处	被引量
	1	Metabolic pathway analysis of Scheffersomyces(Pichia)stipitis:effect of oxygen availability on ethanol synthesis and flux distributions显示文摘	Unrean P Nguyen NH		0，，05：	1
	2	Optimized fed-batch fermentation of Scheffersomyces stipitis for efficient production of ethanol from hexoses and pentoses显示文摘	Unrean P Nguyen N H	2013	Applied Biochemistry and Biotechnology2013，169，6：	1
	3	Metabolic networks evolve towards states of maximum entropy production显示文摘	Unrean P Srienc F	2011	Metab Eng2011，13，6：	1
	4	Minimal Escheriehia coli cell for the most efficient production of ethanol from hexoses and pentoses显示文摘	TRINH C T UNREAN P SRIENC F	2008	Applied and Environmental Microbiology2008，74，12：	1
	5	Journal of microbiology and biotechnology 显示文摘	Sukumprasertsri Monton Unrean Pornkamol Pimsamarn Jindarat	2013	Jounral of Microbiology and Biotechnology2013，23，3：	1
	6	Pathway analysis of Pichia pastoris to elucidate methanol metabolism and its regulation for production of recombinant proteins 显示文摘	P Unrean	2014	Biotechnology Progress2014，30，1：	1
	7	Minimal escherichia coli cell for the most efficient production of ethanol from hexoses and pentoses显示文摘	Trinh C.T Unrean P Srienc F		0，，12：	1
	8	Systematic development of biomass overproducing Scheffersomyces stipitis for high-cell-density fermentations显示文摘The development of economically feasible bio-based process requires efficient cell factories capable of producing the desired product at high titer under high-cell-density fermentation.Herein we present a combinatorial approach based on systems metabolic engineering and metabolic evolution for the development of efficient biomass-producing strain.Systems metabolic engineering guided by flux balance analysis(FBA)was first employed to rationally design mutant strains of Scheffersomyces stipitis with high biomass yield.By experimentally implementing these mutations,the biomass yield was improved by 30%in GPD1,25%in TKL1,30%in CIT1,and 44%in ZWF1 overexpressed mutants compared to wild-type.These designed mutants were further fine-tuned through metabolic evolution resulting in the maximal biomass yield of 0.49 g-cdw/g-glucose,whichmatcheswell with predicted yield phenotype.The constructed mutants are beneficial for biotechnology applications dealing with high cell titer cultivations.This work demonstrates a solid confirmation of systems metabolic engineering in combination with metabolic evolution approach for efficient strain development,which could assist in rapid optimization of cell factory for an economically viable and sustainable bio-based process.	Pornkamol Unrean Sukanya Jeennor Kobkul Laoteng Thailand Science Park Phahonyothin Road Klong Nueng Klong Luang Thailand	2016	Synthetic and Systems Biotechnology2016，1，1：	0

返回顶部每页显示：

共1页首页上一页第1页下一页末页 /1 跳转

goolge学术搜索-维普

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1　渝公网安备 50019002500403号　违法和不良信息举报中心

互联网出版许可证新出网证(渝)字10号全国400电话 - 免长途话费