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| 1 | Antimicrobial susceptibility patterns of Streptococcus pneumoniae over 6 years at Gondar University Hospital, Northwest Ethiopia显示文摘Objective:To assess the magnitude and antimicrobial susceptibility patterns ofStreptococcus pneumoniaeisolates from various clinical specimens.Methods:A record based on retrospectivestudy was conducted at Gondar University Teaching Hospital from September 2007 to January 2012.All patients who visited Gondar University Hospital and provided clinical specimens(body fluids,discharge,swab and blood)for routine bacteriological culturing and antimicrobial susceptibilitytesting were taken for analysis.Clinical specimens were processed for bacterial culture accordingto the standard procedures.Antimicrobial susceptibility test for isolated organisms was doneusing agar disk diffusion method.The data were entered and analyzed using SPSS software version16 package.Results:One hundred and fifty threeStreptococcus pneumoniaewere isolated frompatients who visited Gondar University Teaching Hospital bacteriology laboratory for culture.Majority of the pneumococcal isolates were from inpatients[111(72.5%)],and 74(48.4%)were frombody fluids.Out of the total isolates,93(61%)were found to be resistant to at least one antibioticused for susceptibility testing.Forty eight(43.2%)of the isolates were multi-drug resistant(resistantto two or more drugs).The resistance rate noted for both ciprofloxacin 17(11.1%)and ceftriaxone15(9.8%)were alarming.Conclusions:High proportions of the isolates tend to be increasinglyresistant to the commonly prescribed drugs.The recommended drug of choice like ciprofloxacinand ceftriaxone were found to be less susceptible in the study area.Based on the findings,wetherefore recommend that antimicrobial agents should be inspected for acceptable activity beforethey are prescribed and administered empirically.Further study with a better design and surveyof antimicrobial susceptibility at large scale shoule be performed to draw advanced information. | Belay Anagaw Mucheye Gezachew Fantahun Biadgelgene Berhanu Anagaw Tariku Geleshe Birke Taddese Birhanu Getie Mengistu Endris Andargachew Mulu Chandrashekhar Unakal | 2013 | Asian Pacific Journal of Tropical Biomedicine2013，3，7： | 3 |
| 2 | Absorbed dose estimates at the cellular level for ^131I显示文摘 | Perihan Unak Berkan Cetinkaya | 2005 | Applied Radiation and Isotopes2005，，62： | 1 |
| 3 | Radiolabeling of bombesin- like peptide with 99mTc: 99mTc-litorin and biodistribution in rats 显示文摘 | Durkan K Lambrecht FY Unak P | 2007 | Bioconjugate Chemistry2007，18，5： | 1 |
| 4 | Newradio labeled CCK-8 analogues:reparation and biodistribution studies in ratsand rabbits显示文摘 | Ertay T Unak P Bekis R | 2001 | Nucl MedBiol2001，28，6： | 1 |
| 5 | Gold nanoparticle probes: design and in vitro applications in cancer cell euhure显示文摘 | Unak G Ozkaya F Medine EI | 2012 | Colloids Surf B Biointerfaces2012，90，： | 1 |
| 6 | Prevalence of potential drug–drug interactions among internal medicine ward in University of Gondar Teaching Hospital, Ethiopia显示文摘 | Akshaya Srikanth Bhagavathula Alemayehu Berhanie Habtamu Tigistu Yishak Abraham Yosheph Getachew Tahir Mehmood Khan Chandrashekhar Unakal | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，，： | 1 |
| 7 | What is the Potential Use of Thorium in the Future Energy Production Technology显示文摘 | | | Progress in Nuclear Technology0，37，14： | 1 |
| 8 | L-camitine protection against cisplatin nephrotoxicity in rats: Comparison with amifostin using quantitative renal Tc 99m DMSA uptake显示文摘 | Yurekli Y Unak P Yenisey C | 2011 | Mol Imaging Radio- nucl Ther2011，20，1： | 1 |
| 9 | Radioiodinated magnetic ta- rgeted carriers (1311-MTC)显示文摘 | Dagdeviren K Unak P Bekis R | 2007 | Journal of Radioanalytical and Nu- clear Chemistry2007，273，3： | 1 |
| 10 | Prevalence and antibiotic susceptibility of Staphylococcusɑureus from bovine mastitis显示文摘 | UNAKAL C G KALIWAL B B | 2010 | Vet World2010，3，2： | 1 |
| 11 | What is the potential use of thorium in the future energy production technology显示文摘 | Unak T | 2000 | Progress in Nuclear Energy2000，37，14： | 1 |
| 12 | Characteristics of bacterial sepsis among patients with visceral leishmaniasis显示文摘Sepsis is one of the major causes and predictors of death in patients with visceral leishmaniasis(VL).Globally,incidence rate of sepsis ranged from 56-91 cases per 100000 people,with a mortality rate of 30%.Incidence of sepsis has been raised due to aging of the population and the higher incidence of immunosuppressive conditions such as HIV.VL and others.The prevalence of sepsis was reported from 4.2%to 32.3%and 14.1%in VL and VL-HIV coinfectcd patients,respectively.The mortality rate of VL patients with sepsis is greater than50%.Factors associated with sepsis in VL patients are immune suppression,pancytopenia.HIV co-infection,age 40 years old,indwelling of central venous lines and hospitalization.Although antimicrobial susceptibility patterns were not well reported,both Gram-positive and Gram-negative bacteria were isolated from patients with VL.So far.limited information is available on sepsis in VL.especially in VL-HIV coinfected patients.Therefore,further studies about sepsis prevalence,causative agents and their antibiotic patterns,and associated factors among VL and VL-HIV coinfectcd patients arc necessary.This review provides information about bacterial sepsis in patients with VL. | Mengistu Endris Yegnasew Takele Desalegn Woldeyohannes Chandrashekhar Unakal Feleke Moges Moges Tiruneh Ermias Diro | 2014 | Asian Pacific Journal of Tropical Biomedicine2014，4，11： | 0 |
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