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1Pyogenic liver abscess: Changing patterns in approach显示文摘AIM: To define optimum management of the pyogenic liver abscess and assess new trends in treatment. METHODS: One hundred and sixty nine patients with pyogenic liver abscess managed at Sher-i-Kashmir In- stitute of Medical Sciences, Srinagar, Kashmir (India) from July 2001 to August 2006 were studied to evaluate and define the optimum treatment. RESULTS: Mortality in the surgically treated group of patients was 9.4% (12/119), while those treated non-surgically had a fatality rate of 16.66% (7/42). Multiple liver abscesses treated surgically had a surprisingly low mortality of 30%. The biliary tract (64.97%) was the most common cause of liver abscess. Multiple abscesses, mixed organisms and abscess complications are all associated with a significantly increased mortality. However, the lethality of the primary disease process was the most important factor in determining survival.CONCLUSION: Transperitoneal surgical drainage and antibiotics are the mainstay of treatment. Percutaneous drainage is recommended for high risk patients only.Ajaz A Malik Shams UL Bari Khawaja Abdul Rouf Khurshid Alam Wani 2010World Journal of Gastrointestinal Surgery2010,2,12:15
2在良性的胆汁的阻塞的 choledochoduodenostomy 的长期的结果显示文摘 AIM:To determine the long-term results of choledochodudenostomy in patients with benign billiary obstruction.METHODS:This prospective study was conducted at Sheri Kashmir Institute of Medical Sciences Srinagar Kashmir,India over a period of 10 years from January 1997 to December 2007.The total number of patients who underwent choledochoduodenostomy during this period was 270.On the basis of etiology of biliary tract obstruction,patients were divided into a calculus group,an oriental cholangiohepatitis group,a benign biliary stricture group and others.Patients were followed for a variable period of 13 mo to 15 years.RESULTS:Choledochoduodenostomy(CDD) with duodenotomy was performend in four patients.CDD with removal of T-tube,CDD with left hepatic lobectomy and CDD with removal of intra biliary ruptured hydatid was performed in three patients each.In the remaining patients only CDD was performed.Immediate post operative complications were seen in 63(23%) patients,while long-term complications were seen in 28(11%) patients,which were statistically significant.Three patients died during hospitalization while four patients died in the late post-operative period.CONCLUSION:Our conclusion is that CDD is safe and produces good long term results when a permanent biliary drainage procedure is required.Ajaz A Malik Shiraz A Rather Shams UL Bari Khursheed Alam Wani 2012World Journal of Gastrointestinal Surgery2012,4,2:7
3Surgical management of complicated hydatid cysts of the liver显示文摘AIM: To review the clinical presentation and surgical management of complicated hydatid cysts of the liver and to assess whether conservative surgery is adequate in the management of complicated hydatid cysts of liver.METHODS:The study was carried out at Sher-i-Kashmir Institute of Medical Science,Srinagar,Kashmir,India.Sixty nine patients with hydatid disease of the liver were surgically managed from April 2004 to October 2005 with a follow up period of three years.It included 27 men and 42 women with a median age of 35 years.An abdominal ultrasound,computed tomography and serology established diagnosis.Patients with jaundice and high suspicion of intrabiliary rupture were subjected to preoperative endoscopic retrograde cholangiography.Cysts with infection,rupture into the biliary tract and peritoneal cavity were categorized as complicated cysts.Eighteen patients(26%)had complicated cysts and formed the basis for this study.RESULTS:Common complications were infection(14%),intrabiliary rupture(9%)and intraperitoneal rupture(3%).All the patients with infected cysts presented with pain and fever.All the patients with intrabiliary rupture had jaundice,while only four with intrabiliary rupture had pain and only two had fever.Surgical procedures performed in complicated cysts were:infection-omentoplasty in three and external drainage in seven;intrabiliary rupture-omentoplasty in two and internal drainage in four patients.Two patients with intraperitoneal rupture underwent external drainage.There was no mortality.The postoperative morbidity was 50%in complicated cysts and 16%in uncomplicated cysts.CONCLUSION:Complicated hydatid cyst of the liver can be successfully managed surgically with good long term results.Ajaz A Malik Shams UL Bari Ruquia Amin Masooda Jan 2010World Journal of Gastrointestinal Surgery2010,2,3:4
4Oxidative stress in plasma from maple syrup urine disease patients during treatment 显示文摘Barschak AG Sirra A Deon M et ul 2008Metab Brain Dis2008,23,1:1
5Key role for efflux n the preservative susceptibility and adaptive resistance of Burkholderia cepacia complex bacteria显示文摘Rushton L Sass A Baldwin A et ul 2013Antimierobial agents and chemo- therapy2013,57,7:1
6Structural basis of the heterodimerization of the MST and RASSF SARAH domains in the Hippo signalling pathway显示文摘Hwang E Cheong HK Ul Mushtaq A 2014Acta Crystallogr D Biol Crystallogr2014,70,7:1
7Changes in uterine and ovarian arterial impedance during the periovulatory period in conception and nonconception cycle显示文摘YOKOTA A NAKAI A OYA A et ul 2000J Obstet & Gynecol Res2000,26,:1
8Sheep cloned by nuclear transfer from a cultured cell line 显示文摘Campbell K H S McWhir J Ritchi W A et ul 1996Nature1996,380,:1
9Preliminary clinical experience with the Bryan cervical disc prosthesis显示文摘Coffin J Casey A Keht P et ul 2002Neurosurgery2002,51,:1
10Forest litter decomposition in relation to soil nitrogen dynamics and litter quality 显示文摘Mcclaugherty C A Pastor J Aber J D et ul 1985Ecology1985,66,1:1
11Energy and throughput efficient cooperative spectrum sensing in cognitive radio sensor net- works显示文摘EJAZ W SHAH G A UL HASAN N 2015European Transactions on Emerging Telecommunication Technologies2015,26,7:1
12Activity of broad-spectrum T ceils as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT显示文摘Papadopoulou A Gerdemann U Katari UL 2014Sci Transl Med2014,6,24:1
13Causes of fatigue failure in the main bearing of an aero-engine显示文摘A Tauqir I Salam A ul Haq A Q Khan 2000Engineering Failure Analysis2000,,7:1
14GI3 is an essential mediator of platelet activation in hemostasis and thrombosis 显示文摘Moers A Nieswandt B Massberg S et ul 2003Nat Med2003,9,11:1
15The normal range for inter-arm differences in blood pressure 显示文摘Orme S Ralph S G Birchall A et ul 1999Age Ageing1999,28,6:1
16The influence of the alloying elements on the properties of stainless maraging steels at low temperature 显示文摘Lapin P G Gulyaev A P Ul'yanin E A 1972Metallovednie i Termicheskaya Obrabotka Metallov1972,,2:1
17Serum starvation of bovine fetal fibroblasts prior to nuclear transfer increase in vitro development rates 显示文摘Hill J R Winger Q A Jones K L et ul 1999Theriogenology1999,51,1:1
18Determination of the dimerization,distribution,and acid dissociation constants of dialkyl hydrogen phosphates and the association constants of tributyl phosphate and trioctylphosphine oxide in various diluents显示文摘Ul'yanov V S Sviridova R A 1970Radiokhimiya1970,12,1:1
19Leptin receptor genotype at Gln223Arg is associated with body composition, BMD, and vertebral fracture in postmenopausal Danish women 显示文摘Fairbrother UL Tank6 LB Walley A J 2007J Bone Miner Res2007,22,4:1
20Effect of humie and fulvie acid concentrations and ionic strength on eopper and lead binding 显示文摘CHRISTL I METZGER A HEIDMANN I et ul 2005Environmental Science & Technology2005,39,14:1
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