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| 1 | Contemporary review of minimally invasive pancreaticoduodenectomy显示文摘AIM To assess the current literature describing various minimally invasive techniques for and to review short-term outcomes after minimally invasive pancreaticoduodenectomy(PD). METHODS PD remains the only potentially curative treatment for periampullary malignancies, including, most commonly, pancreatic adenocarcinoma. Minimally invasive approaches to this complex operation have begun to be increasingly reported in the literature and are purported by some to reduce the historically high morbidity of PD associated with the open technique. In this systematic review, we have searched the literature for high-quality publications describing minimally invasive techniques for PD-including laparoscopic, robotic, and laparoscopicassisted robotic approaches(hybrid approach). We have identified publications with the largest operative experiences from well-known centers of excellence for this complex procedure. We report primarily short term operative and perioperative results and some short term oncologic endpoints. RESULTS Minimal y invasive techniques include laparoscopic, robotic and hybrid approaches and each of these techniques has strong advocates. Consistently, across all minimally invasive modalities, these techniques are associated less intraoperative blood loss than traditional open PD(OPD), but in exchange for longer operating times. These techniques are relatively equivalent in terms of perioperative morbidity and short term oncologic outcomes. Importantly, pancreatic fistula rate appears to be comparable in most minimally invasive series compared to open technique. Impact of minimally invasive technique on length of stay is mixed compared to some traditional open series. A few series have suggestedthat initiation of and time to adjuvant therapy may be improved with minimally invasive techniques, however this assertion remains controversial. In terms of shortterms costs, minimally invasive PD is significantly higher than that of OPD. CONCLUSION Minimally invasive approaches to PD show great promise as a strategy to improve short-term outcomes in patients undergoing PD, but the best results remain isolated to high-volume centers of excellence. | Rui Dai Ryan S Turley Dan G Blazer | 2016 | World Journal of Gastrointestinal Surgery2016，8，12： | 5 |
| 2 | Generation of large numbers of immature and mature dendritic cells from rat bone marrow cultures显示文摘 | Talmor M Mirza A Turley S | 1998 | Eur J Immunol1998，28，3： | 1 |
| 3 | The distribution and expression of the two isoforms of DNA topoisomerase Ⅱ in nomal and neoplastic human tissues显示文摘 | Turley H Comley M Houlbrook S | 1997 | Cancer1997，75，9： | 1 |
| 4 | Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: role for transforming growth factor beta 显示文摘 | Turley JM Funakoshi S Ruseetti FW | 1995 | Cell Growth Differ1995，6，6： | 1 |
| 5 | beta-Catenin stabilization dysregulates mesenchymal cell proliferation, motility, and invasiveness and causes aggressive fibromatosis and hyperplastic cutaneous wounds 显示文摘 | Cheon SS Cheah AY Turley S | 2002 | Proc Natl Acad Sei USA2002，99，10： | 1 |
| 6 | Marine snow studies in the northeast Atlantic: distribution, composition and roles as a food source for migrating plankton显示文摘 | Lampitt R S Wishner K F Turley C M | 1993 | Marine Biology1993，116，4： | 1 |
| 7 | The type Ⅲ transforming growth factor-beta receptor as a novel tumor suppressor gene in prostate cancer显示文摘 | Turley R S Finger E C Hempel N | 2007 | Cancer Res2007，67，3： | 1 |
| 8 | Plant sterols andplant stanols in the management of dyslipidaemia andprevention of cardiovascular disease 显示文摘 | Gylling H Plat J Turley S | 2014 | Atherosclero-sis2014，232，： | 1 |
| 9 | Inhibition of cholesterol absorption by SCH 58053 in the mouse is not mediated via changes in the expression of mRNA for ABCA1 ,ABCG5 or ABCG8 in the enterocyte显示文摘 | Repa J Dietschy J Turley S | 2002 | Lipid Res2002，43，： | 1 |
| 10 | The formation of immunogenic MHC class Ⅱ -peptide ligands in lysosomal compartments of dendritic cells is regulated by inflammatory stimuli显示文摘 | Inaba K Turley S Iyoda T | 2000 | J Exp Med2000，191，6： | 1 |
| 11 | Combining confluent and fractionally abla- tive modalities of a novel 2 790nm YSGG laser for facial resurfacing显示文摘 | Munavalli GS Turley A Silapunt S | 2011 | Lasers Surg Med2011，43，4： | 1 |
| 12 | The distribution and expression of the two isoforms of DNA topoisomerase Ⅱ in normal and neoplastic human tissues显示文摘 | Turley H Comley M Houlbrook S | 1997 | Br J Cancer1997，75，9： | 1 |
| 13 | The induction of tolerance by dendritic cells that have captured apoptotic cells显示文摘 | Steinman R M Turley S Mellman I | 2000 | J Exp Med2000，191，3： | 1 |
| 14 | The hypoxia regulated transcription factor DEC1 (Stral3, SHARP-2) and its ex pression in human tissues and tumours显示文摘 | Turley H Wykoff CC Troup S | | J Pathol0，203，3： | 1 |
| 15 | The induction of tolerance by dendritic cells that have captured apoptotic cells显示文摘 | Stemnan RM Turley S Mellman I | 2000 | Exp Med2000，191，3： | 1 |
| 16 | Sterol absorption by the small intestine显示文摘 | Turley S D Dietsehy J M | 2003 | Current Opinion in Lipidology2003，14，3： | 1 |
| 17 | The intestinal absorption of biliary and dietary cholesterol as a drug target for lowering the plasma cholesterol level显示文摘 | Turley S D Dietschy J M | 2003 | Preventive Cardiology2003，6，1： | 1 |
| 18 | The effect of ortho- dontic extrusion on traumatically intruded teeth显示文摘 | Turley PK Joiner MW Hellstrom S | 1984 | Am J Orthod1984，85，： | 1 |
| 19 | Cholesterol and bile acids metabolism are impaired in mice lacking the nuclear oxysterol receptor LXA a 显示文摘 | Peet D J Turley S D Ma W | 1998 | Cell1998，93，： | 1 |
| 20 | Cholesterol and bile acid metabolism are impaired in mice lacking the nuclear oxysterol receptor LXR alpha显示文摘 | PEET D J TURLEY S D MA W | 1998 | Cell1998，93，： | 1 |
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