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| 1 | High prevalence of nonalcoholic fatty liver in patients with idiopathic venous thromboembolism显示文摘AIM:To assess the prevalence of nonalcoholic fatty liver disease (NAFLD) in patients with idiopathic venous thromboembolism (VTE). METHODS:In a case-control study,after excluding subjects with well-consolidated risk factors for VTE,idiopathic VTE was documented in 138 consecutive patients who were referred to our department. Two hundred and seventy-six healthy sex/age/body-massindex-matched subjects,without any clinical/instrumental evidence of VTE,served as controls. All underwent a clinical/laboratory/ultrasound assessment for the presence of metabolic syndrome and NAFLD. RESULTS:NAFLD was detected in 112/138 cases (81%) and in 84/276 controls (30%) [risk ratio:2.7,95% confidence interval (CI):2.2-3.2,P < 0.0001]. Metabolic syndrome and smoking habit were more prevalent in patients with idiopathic VTE. The high prevalence of NAFLD in VTE was also confirmed after adjustment for inherited thrombophilia. NAFLD was clearly predicted by VTE (odds ratio:1.8,95% CI:1.2-2.7,P < 0.0001). | Matteo Nicola Dario Di Minno Antonella Tufano Anna Rusolillo Giovanni Di Minno Giovanni Tarantino | 2010 | World Journal of Gastroenterology2010，16，48： | 5 |
| 2 | 人类角质形成细胞中调节细胞内信号传导的Toll样受体(TLR2)对糠秕马拉色菌的反应显示文摘Toll-like receptors (TLRs) are crucial players in the innate immune response to microbial invaders. The lipophilic yeast Malassezia furfur has been implicated in the triggering of scalp lesions in psoriasis. The aim of the present study was to assess the role of TLRs in the defence against M. furfur infection. The expression of the myeloid differentiation factor 88 (MyD88) gene, which is involved in the signalling pathway of many TLRs, was also analysed. In addition, a possible correlation of antimicrobial peptides of the β -defensin family to TLRs was tested. Human keratinocytes infected with M. furfur and a variety oiM. furfur-positive psoriatic skin biopsies were analysed by RT-PCR, for TLRs, MyD88, human β -defensin 2 (HBD- 2), HBD- 3 and interleukin- 8 (IL- 8) mRNA expression. When keratinocytes were infected with M. furfur, an up-regulation for TLR2, MyD88, HBD- 2, HBD- 3 and IL- 8 mRNA was demonstrated, compared to the untreated cells. The same results were obtained when psoriatic skin biopsies were analysed. The M. furfur-induced increase in HBD- 2 and IL- 8 gene expression is inhibited by anti-TLR2 neutralising antibodies, suggesting that TLR2 is involved in the M. furfur-induced expression of these molecules. These findings suggest the importance of TLRs in skin protection against fungi and the importance of keratinocytes as a component of innate immunity. | Baroni A. Orlando M. Donnarumma G. M.A. Tufano 刘艳 | 2006 | 世界核心医学期刊文摘(皮肤病学分册)2006，2，3： | 4 |
| 3 | What drives corporate liquidity? An international survey of cash holdings and lines of credit显示文摘 | Karl V. Lins Henri Servaes Peter Tufano | 2010 | Journal of Financial Economics2010，，1： | 3 |
| 4 | Chapter 6 Financial innovation显示文摘 | Peter Tufano | 2003 | Handbook of the Economics of Finance2003，，： | 2 |
| 5 | BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer 显示文摘 | Xing M Westra HW Tufano RP | 2005 | J Clin Endocrinol Metab2005，90，12： | 1 |
| 6 | Focus on risk factors for fungal infections in ICU pa- tients 显示文摘 | Tufano R | 2002 | Minerva Anestesiol2002，68，： | 1 |
| 7 | BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer显示文摘 | Xing M Westra WH Tufano RP | 2005 | J ClinEndocrinolMetab2005，90，2： | 1 |
| 8 | BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer显示文摘 | Xing M Westra WH Tufano RP | 2005 | J Clin Endocrinol Metab2005，90，12： | 1 |
| 9 | Focus on risk factors for fungal infections in ICU patients显示文摘 | Tufano R | 2002 | Minerva Anestesiol2002，68，： | 1 |
| 10 | Ameloblastic carcinoma of the maxilla显示文摘 | Dhir K Seiubba J Tufano R P | 2003 | Oral Oneel2003，39，7： | 1 |
| 11 | Heat recovery in distillation by means ofabsorption heat pumps and heat transformers 显示文摘 | Vincenzo Tufano | 1997 | AppliedThermal Engineering1997，17，2： | 1 |
| 12 | Costly search and mutual fund flows 显示文摘 | Sirri E R Tufano P | 1998 | Journal of Finance1998，，53： | 1 |
| 13 | Sphincter-sav-Ingsurgery in low rectal cancer显示文摘 | Guerriero O Tufano G Pennetti L | 2006 | Chir Ital2006，58，1： | 1 |
| 14 | Explaining the size of the mutual fund industry around the world 显示文摘 | Khorana A Servaes H Tufano P | 2005 | Journal of Financial Economics2005，78，1： | 1 |
| 15 | Costly search and mutual fund flows 显示文摘 | Sirri E Tufano P | 1998 | Journal of Finance1998，53，5： | 1 |
| 16 | Detection of herpesvirus DNA in peripheral blood mononuclear cells and skin lesions of patients with pempbigus by polymerase chain reaction 显示文摘 | Tufano MA Baroni A Buommino E | 1999 | Br J Dermatol1999，141，6： | 1 |
| 17 | Costly search and mutual fund flows显示文摘 | Sirri E P Tufano | 1998 | Journal of Finance1998，53，5： | 1 |
| 18 | The reproducibility of isokinetic dynamometry data显示文摘 | Caruso JF Brown LE Tufano JJ | 2012 | Isokinetics and Exercise Science2012，20，4： | 1 |
| 19 | Management of recur- rent/persistent nodal disease in patients with differentiated thyroid cancer: a critical review of the risks and benefits of surgical inter- vention versus active surveillance 显示文摘 | Tufano RP Clayman G Heller KS | 2015 | Thyroid2015，25，1： | 1 |
| 20 | The use oferythropoietin in cerebral diseases显示文摘 | Cotena S Piazza O Tufano R | 2008 | Panminerva-Med2008，50，2： | 1 |
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