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5篇 您的检索式:作者名="Tucker Stuart"
    题名 作者 年代 出处 被引量
1Intra-islet endothelial cell and β-cell crosstalk: Implication for islet cell transplantation显示文摘The intra-islet microvasculature is a critical interface between the blood and islet endocrine cells governing a number of cellular and pathophysiological processes associated with the pancreatic tissue. A growing body of evidence indicates a strong functional and physical interdependency of β-cells with endothelial cells(ECs), the building blocks of islet microvasculature. Intra-islet ECs, actively regulate vascular permeability and appear to play a role in fine-tuning blood glucose sensing and regulation. These cells also tend to behave as 'guardians', controlling the expression and movement of a number of important immune mediators, thereby strongly contributing to the physiology of islets. This review will focus on the molecular signalling and crosstalk between the intra-islet ECs and β-cells and how their relationship can be a potential target for intervention strategies in islet pathology and islet transplantation.Siddharth Narayanan Gopalakrishnan Loganathan Maheswaran Dhanasekaran William Tucker Ankit Patel Venugopal Subhashree SriPrakash Mokshagundam Michael G Hughes Stuart K Williams Appakalai N Balamurugan 2017World Journal of Transplantation2017,7,2:1
2DSG2 Mutations Contribute to Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy显示文摘Mark M. Awad Darshan Dalal Eunpi Cho Nuria Amat-Alarcon Cynthia James Crystal Tichnell April Tucker Stuart D. Russell David A. Bluemke Harry C. Dietz Hugh Calkins Daniel P. Judge 2006The American Journal of Human Genetics2006,,1:1
3Spinal cord monitoring in neuromuscular scoliosis显示文摘Stuart K Tucker FR 2001J Pediatr Orthop B2001,10,:1
4Spinal cord monitoring in neuromuscular scoliosis显示文摘Stuart K Tucker FR 2001Pediatr Orthop B2001,10,:1
5Wireless,battery-free,and fully implantable electrical neurostimulation in freely moving rodents显示文摘Implantable deep brain stimulation(DBS)systems are utilized for clinical treatment of diseases such as Parkinson's disease and chronic pain.However,long-term efficacy of DBS is limited,and chronic neuroplastic changes and associated therapeutic mechanisms are not well understood.Fundamental and mechanistic investigation,typically accomplished in small animal models,is difficult because of the need for chronic stimulators that currently require either frequent handling of test subjects to charge battery-powered systems or specialized setups to manage tethers that restrict experimental paradigms and compromise insight.To overcome these challenges,we demonstrate a fully implantable,wireless,battery-free platform that allows for chronic DBS in rodents with the capability to control stimulation parameters digitally in real time.The devices are able to provide stimulation over a wide range of frequencies with biphasic pulses and constant voltage control via low-impedance,surface-engineered platinum electrodes.The devices utilize off-the-shelf components and feature the ability to customize electrodes to enable broad utility and rapid dissemination.Efficacy of the system is demonstrated with a readout of stimulation-evoked neural activity in vivo and chronic stimulation of the medial forebrain bundle in freely moving rats to evoke characteristic head motion for over 36 days.Alex Burton Sang Min Won Arian Kolahi Sohrabi Tucker Stuart Amir Amirhossein Jong Uk Kim Yoonseok Park Andrew Gabros John A.Rogers Flavia Vitale Andrew G.Richardson Philipp Gutruf 2021Microsystems & Nanoengineering2021,7,4:0
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