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12篇 您的检索式:作者名="Tran TK"
    题名 作者 年代 出处 被引量
1Very selective suppression pulses for clinical MRSI studies of brain and prostate cancer显示文摘Tran TK Vigneron DB Sailasuta N 2000Magn Reson Med2000,43,1:1
2Single-voxel oversampled J-resolved spectroscopy of in vivo human prostate tissue 显示文摘Swanson MG Vigneron DB Tran TK 2001Magn Reson Med2001,45,6:1
3Urban-rural disparities in antenatal care utilization:A study of two cohorts of pregnant women in Vietnam显示文摘Tran TK Nguyen C Nguyen H 2011BMC Health Serv Res2011,11,:1
4Can short-term fasting protect against doxorubicin-induced cardiotoxicity?显示文摘Doxorubicin(Dox) is one of the most effective chemotherapeutic agents used in the treatment of several types of cancer. However the use is limited by cardiotoxicity. Despite extensive investigation into the mechanisms of toxicity and preventative strategies, Dox-induced cardiotoxicity still remains a major cause of morbidity and mortality in cancer survivors. Thus, continued research into preventative strategies is vital. Short-term fasting has proven to be cardioprotective against a variety of insults. Despite the potential, only a few studies have been conducted investigating its ability to prevent Dox-induced cardiotoxicity. However, all show proof-of-principle that short-term fasting is cardioprotective against Dox. Fasting affects a plethora of cellular processes making it difficult to discern the mechanism(s) translating fasting to cardioprotection, but may involve suppression of insulin and insulin-like growth factor-1 signaling with stimulated autophagy. It is likely that additional mechanisms also contribute. Importantly, the literature suggests that fasting may enhance the antitumor activity of Dox. Thus, fasting is a regimen that warrants further investigation as a potential strategy to prevent Dox-induced cardiotoxicity. Future research should aim to determine the optimal regimen of fasting, confirmation that this regimen does not interfere with the antitumor properties of Dox, as well as the underlying mechanisms exerting the cardioprotective effects.Amie J Dirks-Naylor Samir A Kouzi Sendra Yang Ngan TK Tran Joseph D Bero Raean Mabolo Diep T Phan Stephanie D Whitt Heather N Taylor 2014World Journal of Biological Chemistry2014,5,3:1
5Effects of acute doxorubicin treatment on hepatic proteome lysine acetylation status and the apoptotic environment显示文摘AIM: To determine if doxorubicin(Dox) alters hepatic proteome acetylation status and if acetylation status was associated with an apoptotic environment. METHODS: Doxorubicin(20 mg/kg; Sigma, Saint Louis, MO; n = 8) or NaCl(0.9%; n = 7) was administered as an intraperitoneal injection to male F344 rats, 6-wk of age. Once animals were treated with Dox or saline, all animals were fasted until sacrifice 24 h later. RESULTS: Dox treatment decreased proteome lysine acetylation likely due to a decrease in histone acetyltransferase activity. Proteome deacetylation may likely not be associated with a proapoptotic environment. Dox did not increase caspase-9,-8, or-3 activation nor poly(adenosine diphosphate-ribose) polymerase-1 cleavage. Dox did stimulate caspase-12 activation, however, it likely did not play a role in apoptosis induction. CONCLUSION: Early effects of Dox involve hepatic proteome lysine deacetylation and caspase-12 activa-tion under these experimental conditions.Amie J Dirks-Naylor Samir A Kouzi Joseph D Bero Ngan TK Tran Sendra Yang Raean Mabolo 2014World Journal of Biological Chemistry2014,5,3:1
6Very selective sup- pression pulses for clinical MRSI studies of brain and prostate cancer显示文摘Tran TK Vigneron DB Sailasuta N 2000Magn Reson Med2000,43,1:1
7Single -voxel oversampled J- Resolved spectroscopy of in vivo human prostate tissue 显示文摘Swanson MG Vigneron DB Tran TK 2001Magn Reson Med2001,45,:1
8Magnetic resonance imaging and spectroscopic imaging of prostate cancer显示文摘Swanson MG Vigneron DB Tran TK 2001Cancer Invest2001,19,5:1
9Determination of optimal conditions for hydrolysis of conjugated deoxynivalenol in com andwheat with trifluoromethanesulfonic acid 显示文摘Tran ST Smith TK 2011Animal Feed Science and Technology2011,163,:1
10Synthetic LXR ligand inhibits the development of atherosclerosis in mice显示文摘Joseph SB McKilligin E Pei L Watson MA Collins AR Laffitte BA Chen M Noh G Goodman J Hagger GN Tran J Tippin TK Wang X Lusis A J Hsueh WA Law RE Collins JL Willson TM Tontonoz P 0,,11:1
11Determination of optimal conditions for hydrolysis of conjugated deoxynivalenol in corn andwheat0 with trifluoromethanesulfonic acid显示文摘Tran ST Smith TK 2011Animal Feed Science and Technology2011,163,:1
12Single-voxel oversampled J-resolved spectroscopy of in vivo human prostate tissue显示文摘Swanson MG Vigneron DB Tran TK 2001Magn Reson Med2001,45,6:1
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