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| 1 | Transrectal ultrasound and magnetic resonance imaging measurement of extramural tumor spread in rectal cancer显示文摘AIM:To evaluate the agreement between transrectal ultrasound(TRUS) and magnetic resonance imaging(MRI) in classification of ≥ T3 rectal tumors.METHODS:From January 2010 to January 2012,86 consecutive patients with ≥ T3 tumors were included in this study.The mean age of the patients was 66.4 years(range:26-91 years).The tumors were all ≥ T3 on TRUS.The sub-classification was defined by the penetration of the rectal wall:a:0 to 1 mm;b:1-5 mm;c:6-15;d:> 15 mm.Early tumors as ab(≤ 5 mm) and advanced tumors as cd(> 5 mm).All patients underwent TRUS using a 6.5 MHz transrectal transducer.The MRI was performed with a 1.5 T Philips unit.The TRUS findings were blinded to the radiologist performing the interpretation of the MRI images and measuring the depth of extramural tumor spread.RESULTS:TRUS found 51 patients to have an early ≥ T3 tumors and 35 to have an advanced tumor,whereas MRI categorized 48 as early ≥ T3 tumors and 38 as advanced tumors.No patients with tumors classified as advanced by TRUS were found to be early on MRI.The kappa value in classifying early versus advanced T3 rectal tumors was 0.93(95% CI:0.85-1.00).We found a kappa value of 0.74(95% CI:0.63-0.86) for the total sub-classification between the two methods.The mean maximal tumor outgrowth measured by TRUS,5.5 mm ± 5.63 mm and on MRI,6.3 mm ± 6.18 mm,P = 0.004.In 19 of the 86 patients the following CT scan or surgery revealed distant metastases;of the 51 patients in the ultrasound ab group three(5.9%) had metastases,whereas 16(45.7%) of 35 in the cd group harbored distant metastases,P = 0.00002.The odds ratio of having distant metastases in the ultrasound cd group compared to the ab group was 13.5(95% CI:3.5-51.6),P = 0.00002.The mean maximal ultrasound measured outgrowth was 4.3 mm(95% CI:3.2-5.5 mm) in patients without distant metastases,while the mean maximal outgrowth was 9.5 mm(95% CI:6.2-12.8 mm) in the patients with metastases,P = 0.00004.Using the MRI classification three(6.3%) of 48 in the MRI ab group had distant metastases,while 16(42.1%) of the 38 in the MRI cd group,P = 0.00004.The MRI odds ratio was 10.9(95% CI:2.9-41.4),P = 0.00008.The mean maximal MRI measured outgrowth was 4.9 mm(95% CI:3.7-6.1 mm) in patients without distant metastases,while the mean maximal outgrowth was 11.5 mm(95% CI:7.8-15.2 mm) in the patients with metastases,P = 0.000006.CONCLUSION:There is good agreement between TRUS and MRI in the pretreatment sub-classification of ≥ T3 tumors.Distant metastases are more frequent in the advanced group. | Sφren R Rafaelsen Chris Vagn-Hansen Torben Sφrensen John Plφen Anders Jakobsen | 2012 | World Journal of Gastroenterology2012，18，36： | 14 |
| 2 | Diagnostic Accuracy of Capsule Endoscopy for Small Bowel Crohn’s Disease Is Superior to That of MR Enterography or CT Enterography显示文摘 | Michael Dam Jensen Torben Nathan S?ren Rafael Rafaelsen Jens Kjeldsen | 2011 | Clinical Gastroenterology and Hepatology2011，，2： | 3 |
| 3 | Role of nitric oxide in neutrally induced pancreatic exocrine secretion in pigs显示文摘 | Hoist JJ Torben NR Roter S | 1994 | Am Physlcal1994，266，21： | 1 |
| 4 | 查看详情显示文摘 | Torben S Thomas M Kjartan F Sφren L F Christian P | | 0，，： | 1 |
| 5 | Melt agglomeration with polyethylene glycol beads at a low impeller speed in a high shear mixer显示文摘 | ANETTE S TORBEN S | 2001 | European Journal of Pharmaceutics and Biopharmaceutics2001，52，3： | 1 |
| 6 | Multidimensional data modeling for location-based services显示文摘 | Christian S Jensen Augustas Kligys Torben Bach Pedersen Igor Timko | | The International Journal on Very Large Data Bases Issue0，13，1： | 1 |
| 7 | Lake and catchment management in Denmark显示文摘 | Erik Jeppesen Martin S?ndergaard Brian Kronvang Jens P. Jensen Lars M. Svendsen Torben L. Lauridsen | 1999 | Hydrobiologia1999，，0： | 1 |
| 8 | Non-parametric Algorithmic Generation of Neuronal Morphologies显示文摘 | Torben N B Vanderlooy S Postma E O | 2008 | Neuroinformatics2008，6，4： | 1 |
| 9 | Product market integration and heterogeneity- Rent sharing and pricing to market显示文摘 | Torben M Andersen Allan Sφrensen | 2008 | Review of International Economics2008，16，2： | 1 |
| 10 | Location-Based Services - a database perspective显示文摘 | CHRISTIAN S J ANDERS F C TORBEN B P | 2001 | Scan GIS2001，，7： | 1 |
| 11 | Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: Studies in 6018 whites显示文摘 | Dorit P. Jensen S?ren A. Urhammer Hans Eiberg Knut Borch-Johnsen Torben J?rgensen Torben Hansen Oluf Pedersen | 2006 | Molecular Genetics and Metabolism2006，，4： | 1 |
| 12 | The effect of droplet size and powderparticle size on the mechanisms of nucleation and growth in the fluidbed melt agglomeration 显示文摘 | Thomas A Anette S Torben S | 2002 | International Journal of Pharmaceutics2002，249，1： | 1 |
| 13 | Drugs in blood samples from unconscious drug addicts after the intake of an overdose显示文摘 | Anni Steentoft Karen Worm Erik Nielsen Carsten Boe Pedersen Michael Sprehn Torben Mogensen Mogens Bredgaard S?rensen | 1996 | International Journal of Legal Medicine1996，，5： | 1 |
| 14 | Mutation analysis of the preproghrelin gene: No association with obesity and type 2 diabetes显示文摘 | Lesli H. Larsen Anette P. Gjesing Thorkild I.A. S?rensen Yasmin H. Hamid S?ren M. Echwald S?ren Toubro Eva Black Arne Astrup Torben Hansen Oluf Pedersen | 2005 | Clinical Biochemistry2005，，5： | 1 |
| 15 | Transrectal ultrasonography and magnetic resonance imaging in the staging of rectal cancer. Effect of experience显示文摘 | S? ren R. Rafaelsen Torben S? rensen Anders Jakobsen Claus Bisgaard Jan Lindebjerg | 2008 | Scandinavian Journal of Gastroenterology2008，，： | 1 |
| 16 | Analyzing rating transitions and rating drift with continuous observations 显示文摘 | David L Torben M S | 2002 | Journal of Banking & Finance2002，26，2： | 1 |
| 17 | Lake and catchment management in Denmark显示文摘 | Erik Jeppesen Martin S?ndergaard Brian Kronvang Jens P. Jensen Lars M. Svendsen Torben L. Lauridsen | 1999 | Hydrobiologia1999，，0： | 1 |
| 18 | Tumor‐promoting macrophages induce the expression of the macrophage‐specific receptor CD163 in malignant cells显示文摘 | Maciej Bogdan Maniecki Anders Etzerodt Benedicte Parm Ulh?i Torben Steiniche Michael Borre Lars Dyrskj?t Torben Falck ?rntoft S?ren Kragh Moestrup Holger Jon M?ller | 2012 | Int J Cancer2012，，10： | 1 |
| 19 | Is There a Trend Towards Global Value Chain Specialization? - An Examination of Cross Border Sales of US Foreign Af- filiates 显示文摘 | BEUGELSDIJK S TORBEN P BENT P | 2009 | Journal of International Management2009，，15： | 1 |
| 20 | A protocol of no sedation for critically ill patients receiving mechanical ventilation : a randomised trial 显示文摘 | Thomas S Torben M Palle T | 2010 | Lancet2010，375，6： | 1 |
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