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| 1 | Rubber band ligation for 750 cases of symptomatic hemorrhoids out of 2200 cases显示文摘AIM: To study the results for the treatment of symptomatic hemorrhoids using rubber band ligation (RBL) method. METHODS: A retrospective study for 750 patients who came to the colorectal unit from June, 1998 to September, 2006, data was retrieved from archived fi les. RBL was performed using the Mc Gown applicator on an outpatient basis. The patients were asked to return to out-patient clinic for follow up at 2 wk, 1 mo, 6 mo and through telephone call every 6 mo for 2 years). RESULTS: After RBL, 696 patients (92.8%) were cured with no difference in outcome for second or third degree hemorrhoids (P = 0.31). Symptomatic recurrence was detected in 11.04% after 2 years. A total of 52 patients (6.93%) had 77 complications from RBL which required no hospitalization. Complications were pain, rectal bleeding and vaso-vagal symptoms(4.13%, 4.13% and 1.33% of patients, respectively). At 1 mo there were a significant improvement in mean SF-36 scores over baseline in five items, while after 2 years there were improvement in all items over baseline, but not significant. No significant manometeric changes after band ligation. CONCLUSION: RBL is a simple, safe and effective method for treating symptomatic second and third degree hemorrhoids as an out patient procedure with signifi cant improvement in quality of life. RBL doesn't alter ano-rectal functions. | Ayman M El Nakeeb Amir A Fikry Waleed H Omar Elyamani M Fouda Tito A El Metwally Hosam E Ghazy Sabry A Badr Mohmed Y Abu Elkhar Salih M Elawady Hisham H Abd Elmoniam Waiel W Khafagy Mosaad M Morshed Ramadan E El Lithy Mohamed E Farid | 2008 | World Journal of Gastroenterology2008，14，42： | 24 |
| 2 | Efficacy and safety of botulinum toxin in treatment of anismus: A systematic review显示文摘AIM: To evaluate the efficacy and safety of botulinum toxin type A(BTX-A) in the management of patients with anismus. METHODS: An organized search of published literature was conducted using electronic databases including: Pub Med/MEDLINE, and Cochrane Central Register of Control ed Trials, also an internet-based search using 'Google Scholar' service was conducted. Both comparative and observational studies were included. We excluded irrelevant articles, editorials, case reports, reviews, and meta-analyses. The studies that followed the patients less than 6 mo were excluded. Variables collected were demographic data of the patients, technique of BTX-A injection and number of sessions, short-term and longterm clinical improvement, post-injection changes in electromyography(EMG), defecography, manometry, and balloon expulsion test, and complications recorded after BTX-A injection.RESULTS: Seven studies comprising 189 patients were included in the review. The median age of the patients was 41.2 years and female-to-male ratio was 1.3:1. The median dose of BTX-A injected per procedure was 100 IU(range, 20-100 IU). Lateral injection was done in five trails and combined lateral and posterior injections in two trials. Three studies used endorectal ultrasonographyguided technique, one study used EMG-guided technique,whereas the remaining three studies used manual palpation with the index finger. The median percentage of patients who reported initial improvement of symptoms was 77.4%(range 37.5%-86.7%), this percentage declined to a median of 46%(range 25%-100%) at 4 mo after injection of BTX-A. Rates of improvement evaluated by balloon expulsion test, EMG, and defecography ranged between(37.5%-80%),(54%-86.7%), and(25%-86.6%), respectively. Fourteen(7.4%) patients developed complications after injection of BTX-A. Complication rates across the studies ranged from 0% to 22.6%. CONCLUSION: Initial satisfactory improvement of symptoms after BTX-A injection remarkably deteriorated after 3 mo of the procedure. However, repeated injection may provide better sustained results with no additional morbidities. Further analysis of more patients is necessary to conclude the safety of BTX-A for the treatment of anismus. | Sameh Hany Emile Hossam Ayman Elfeki Hosam Ghazy Elbanna Mohamed Youssef Waleed Thabet Tito M Abd El-Hamed Basem Said Ahmed Lotfy | 2016 | World Journal of Gastrointestinal Pharmacology and Therapeutics2016，7，3： | 3 |
| 3 | Peptide YY ameliorates ceruleininduced pancreatic injury in the rat显示文摘 | Tito J Rudnicki M Jones D | 1993 | Am J Surg1993，165，3： | 1 |
| 4 | Macromolecular organiza-tion of the Yersinia pestis capsular F1 antigen:insights fromtime-of-flight mass spectrometry显示文摘 | Tito M A Miller J Griffin K F | 2001 | Protein Sci2001，10，11： | 1 |
| 5 | The HumanMicrobiome Projcct:lessons from human genomics显示文摘 | LEWIS C M Jr C)BRECX)N-TlT() A TITO R Y ct al | 2012 | Trends Microbiol2012，20，1： | 1 |
| 6 | Effects of a minor isoleucyl tRNA on heterologous protein translation in Escherichia coli显示文摘 | Del Tito B J Ward J M Hodgson J | 1995 | Biol Technology1995，3，： | 1 |
| 7 | Esterification of Oleic Acid over Solid Acid Catalysts Prepared from Amazon Flint Kaolin显示文摘 | Nascimento L S D L M Z Tito Angélica R S | 2011 | Appl Catal B2011，101，： | 1 |
| 8 | Shear-Flexure Coupling Behavior of Steel Fiber-Reinforced Concrete Beams显示文摘 | Kang Thomas H-K Kim Woosuk Massone Leonardo M Galleguillos Tito A | 2012 | EN2012，，4： | 1 |
| 9 | Complications of microwave abla- tion for liver tumors: results of a multicenter study显示文摘 | Tito L Franca M Luigi S | 2012 | Cardiovascular and Interventional Radiology: A Journal of Imaging in Diagnosis and Treatment2012，35，4： | 1 |
| 10 | The 5-1ipoxygenase/leu-kotriene pathway in obesity, insulin resistance, and fatty liver disease显示文摘 | Martnez-Clemente M Cldria J Titos E | 2011 | Curt Opin Clin Nutr Metab Care2011，14，4： | 1 |
| 11 | Gene expression profiling of renal dysfunction in rats with experimental cirrhosis 显示文摘 | Lopez - Parra M Telleria N Titos E | 2006 | J Hepatol2006，45，2： | 1 |
| 12 | Structural analysis of drug-DNA adducts by tandem mass spectrometry显示文摘 | Iannitti Tito P Weimann A Wickham G Sheil M M | | 0，，： | 1 |
| 13 | Inhibitors of transcription,proteasome inhibitors,and DNA damaging drugs differentially affect feedback of p53 degradation 显示文摘 | An W G Chuman Y F Tito M | 1998 | Exp Cell Res1998，244，1： | 1 |
| 14 | Modelling for Economic Cost and Environmental Analysis of Rainwater Harvesting Systems 显示文摘 | Tito Morales - Pinzon Joan Rieradevall Caries M Gasol | 2015 | Journal of Cleaner Production2015，，87： | 1 |
| 15 | Peptide YY ameliorates cerulein-induced pancreatic injury in the rat显示文摘 | Tito JM Rudnicki M Jones DH | 1993 | Am J Surg1993，165，6： | 1 |
| 16 | The5-li-poxygenase/leukotriene pathway in obesity,insulin resist-ance,and fatty liver disease显示文摘 | Martinez-Clemente M Claria J Titos E | 2011 | Curr Opin Clin Nutr Metab Care2011，14，4： | 1 |
| 17 | Determination of anionic surface active agents using silica coated magnetite nanoparticles modified with cationic surfactant aggregates显示文摘 | FRANCISCO P REGINA M D TITO T ARMANDO D | 2013 | Journal of Chromatograph A2013，1299，7： | 1 |
| 18 | From Single-Molecule Precursors to Coupled Ag2S/Ti O2Nanocomposites显示文摘 | Márcia C Neves Olinda C Monteiro Tito Trindade | 2008 | Eur J Inorg Chem2008，，28： | 1 |
| 19 | Effects of a minor isolated tRNA on heterologous protein translation in Escherichia coli显示文摘 | Del Tito BJ Ward J M Hodgson J | 1995 | Biol Technology1995，3，： | 1 |
| 20 | The sample average approximation method for stochastic discrete optimization显示文摘 | Anton J K Alexander S Tito H M | 2001 | SIAM J on Optimization2001，12，2： | 1 |
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