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| 1 | Dermatofibrosarcoma protuberans: from translocation to targeted therapy显示文摘Dermatofibrosarcoma protuberans(DFSP), the most common dermal sarcoma, is a low-grade, slow growing fibroblastic malignant neoplasm that most frequently affects middle aged adults and is characterized by a high local recurrence rate and a low propensity for metastasis. Wide surgical resection or Mohs micrographic surgery(MMS) are the preferred approaches for localized disease, while radiation therapy is warranted for inoperable disease or for cases with positive margins where re-excision is not possible. DFSP is generally regarded as refractory to conventional chemotherapy. Treatment options for systemic disease were limited until the discovery of a unique translocation, t(17;22)(q22;q13)(COL1A1;PDGFB) found in a majority of cases. In recent years, imatinib, a PDGFβR, ABL and KIT inhibitor, has revolutionized systemic therapy in DFSP. In this review, we summarize the epidemiological, clinical, histological and genetic characteristics of DFSP and update the readers on its current management. | Jonathan Noujaim Khin Thway Cyril Fisher Robin L.Jones | 2015 | Cancer Biology & Medicine2015，12，4： | 4 |
| 2 | Reconstructive Surgery with a Dermal Regeneration Template: Clinical and Histologic Study显示文摘 | Naiem S. Moiemen Jonathan J. Staiano Nkemcho O. Ojeh Yi Thway James D. Frame | 2001 | Plastic and Reconstructive Surgery2001，，1： | 2 |
| 3 | Embedding physics domain knowledge into a Bayesian network enables layer-by-layer process innovation for photovoltaics显示文摘Process optimization of photovoltaic devices is a time-intensive,trial-and-error endeavor,which lacks full transparency of the underlying physics and relies on user-imposed constraints that may or may not lead to a global optimum.Herein,we demonstrate that embedding physics domain knowledge into a Bayesian network enables an optimization approach for gallium arsenide(GaAs)solar cells that identifies the root cause(s)of underperformance with layer-by-layer resolution and reveals alternative optimal process windows beyond traditional black-box optimization.Our Bayesian network approach links a key GaAs process variable(growth temperature)to material descriptors(bulk and interface properties,e.g.,bulk lifetime,doping,and surface recombination)and device performance parameters(e.g.,cell efficiency).For this purpose,we combine a Bayesian inference framework with a neural network surrogate device-physics model that is 100×faster than numerical solvers.With the trained surrogate model and only a small number of experimental samples,our approach reduces significantly the time-consuming intervention and characterization required by the experimentalist.As a demonstration of our method,in only five metal organic chemical vapor depositions,we identify a superior growth temperature profile for the window,bulk,and back surface field layer of a GaAs solar cell,without any secondary measurements,and demonstrate a 6.5%relative AM1.5G efficiency improvement above traditional grid search methods. | Zekun Ren Felipe Oviedo Maung Thway Siyu I.P.Tian Yue Wang Hansong Xue Jose Dario Perea Mariya Layurova Thomas Heumueller Erik Birgersson Armin G.Aberle Christoph J.Brabec Rolf Stangl Qianxiao Li Shijing Sun Fen Lin Ian Marius Peters Tonio Buonassisi | 2020 | npj Computational Materials2020，，1： | 2 |
| 4 | Tumors with EWSR1-CREB1 and EWSR1- ATE1 Fusions : the current status 显示文摘 | Thway K Fisher C | 2012 | Am J Surg Pathol2012，36，7： | 1 |
| 5 | Pathology of soft tissue sarcomas 显示文摘 | Thway K | 2009 | Clinical Ontology2009，21，： | 1 |
| 6 | Solitary fibrous tumors of the soft tissues review of the imaging and clinical features with histopathologie correlation 显示文摘 | Wignall OJ Moskovic EC Thway K | 2010 | AJR2010，195，： | 1 |
| 7 | Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activation显示文摘 | Thway TM Shlykov SG Day MC | 2004 | Cir-culation2004，110，： | 1 |
| 8 | Solitary fibroustumors of the soft tissue: review of the imaging and clinicalfeatures with histopathologic correlation 显示文摘 | Wignall OJ Moskovic EC Thway K | 2010 | AJR2010，195，： | 1 |
| 9 | Aggressive fibromatosis 显示文摘 | Fisher C Thway K | 2014 | Pathology2014，46，2： | 1 |
| 10 | An activator protein-1 complex mediates epidermal growth factor regulation of equine glycoprotein alpha subunit expression in trophoblast cells显示文摘 | Thway TM Wolfe MW | 2002 | Biol Reprod2002，67，3： | 1 |
| 11 | Solitary fibrous tumors of the soft tissues: review of the imaging and clinical features with histopathologic correlation显示文摘 | WlGNALL O J MOSKOVlC E C THWAY K | 2010 | AJR Am J Roentgenol2010，195，1： | 1 |
| 12 | Solitary fibrous tumors of the soft tissues: review of the imaging and clinical features with histopathologic correlation 显示文摘 | Wignall OJ Moskovic EC Thway K | 2010 | AJR2010，195，1： | 1 |
| 13 | Primary cutaneousepithelioid angiosarcoma:a clinicopathologic study of 13 cases ofa rare neoplasm occurring outside the setting of conventionalangiosarcomas and with predilection for the limbs显示文摘 | Suchak R Thway K Zelger B | 2011 | Am J SurgPathol2011，35，1： | 1 |
| 14 | Epidermal growth factor muta- tion as a diagnostic and therapeutic target in metastatic poorly dif-ferentiated thyroid carcinoma : a case report and review of the liter- ature显示文摘 | Lote H Bhosle J Thway K | 2014 | Case Rep 0ncol2014，7，2： | 1 |
| 15 | Antibodies from preeclamptic patients stimulate increased intracellular Ca2+ mobilization through angiotensin receptor activation显示文摘 | Thway T M Shlykov S G Day M C | 2004 | Circulation2004，110，12： | 1 |
| 16 | Antibodies from preeclamptic patients stimulate increased intracellular Ca^2+ mobilization through angiotensin receptor activation显示文摘 | THWAY T M SHLYKO V DAY M C | 2004 | Circulation2004，110，： | 1 |
| 17 | Tumors with EWSR1-CREB1 and EWSR1- ATF1 fusions: the current status 显示文摘 | Thway K Fisher C | 2012 | Am J Surg Pathol2012，36，7： | 1 |
| 18 | Solitary fibrous tumors of the soft tissues: review of the imaging and clinical/b, atures with histopathologic correlation 显示文摘 | Wignall O J Moskovic EC Thway K | 2010 | AJR Am J Roentgenol2010，195，： | 1 |
| 19 | Surgical management of primary retroperitoneal sarcoma显示文摘 | Stauss DC Hayes AJ Thway K | | 0，，05： | 1 |
| 20 | Extramammary Paget disease in a retrorectal dermoid cyst:report of a unique case显示文摘 | Thway K Poison A Pope R | 2008 | Am J Surg Pathol2008，32，4： | 1 |
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