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1篇 您的检索式：作者名="Thomas Blein"

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		题名	作者	年代	出处	被引量
	1	The lncRNA MARS modulates the epigenetic reprogramming of the marneral cluster in response to ABA显示文摘Clustered organization of biosynthetic non-homologous genes is emerging as a characteristic feature of plant genomes.The co-regulation of clustered genes seems to largely depend on epigenetic reprogram-ming and three-dimensional chromatin conformation.In this study,we identified the long non-coding RNA(lncRNA)MARneral Silencing(MARS),localized inside the Arabidopsis marneral cluster,which con-trols the local epigenetic activation of its surrounding region in response to abscisic acid(ABA).MARS modulates the POLYCOMB REPRESSIVE COMPLEX 1(PRC1)component LIKE HETEROCHROMATIN PROTEIN 1(LHP1)binding throughout the cluster in a dose-dependent manner,determining H3K27me3 deposition and chromatin condensation.In response to ABA,MARS decoys LHP1 away from the cluster and promotes the formation of a chromatin loop bringing together the MARNERAL SYNTHASE 1(MRN1)locus and a distal ABA-responsive enhancer.The enrichment of co-regulated lncRNAs in clustered meta-bolic genes in Arabidopsis suggests that the acquisition of novel non-coding transcriptional units may constitute an additional regulatory layer driving the evolution of biosynthetic pathways.	Thomas Roulé Aurelie Christ Nosheen Hussain Ying Huang Caroline Hartmann Moussa Benhamed Jose Gutierrez-Marcos Federico Ariel Martin Crespi Thomas Blein	2022	Molecular Plant2022，15，5：	0

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