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| 1 | Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma显示文摘瞄准:为了评估免疫, interleukin-6 ( IL-6 )和从有肝细胞癌( HCC )和浆液的病人的肿瘤组织标本上的 IL-6 受体( IL-6R )的组织化学的本地化与 HCC 以及肝肝硬化( LC )在一组病人 IL-6 和 sIL-6R 铺平在一组有独自一个的 LC 并且在一个控制组的病人。方法:三组题目被学习:组我(n = 83 ) 受不了 HCC 和 LC,组 II (n = 72 ) 受不了独自一个的 LC 和组 III (n = 42 ) 同样健康的控制。所有病人有丙肝病毒感染。浆液 IL-6 和 IL-6R 层次用一个商业地可得到的 ELISA 工具包被决定。Immunohistochemistry 对 IL-6 和 IL-6R 用 streptavidin-biotin 建筑群和兔子 polyclonal 抗体被执行。结果:Immunohistochemistry 分析显示出媒介到强壮细胞质并且为 IL-6 和 IL-6R 的膜反应分别地在 HCC 的至少 40% 盒子,而肝肝硬化病人和控制为 IL-6 是否定的或为 IL-6R 显示出很温和、焦点的像点的细胞质的反应。在 HCC 组的浆液 IL-6 层次比在 LC 和控制组的那些显著地高(P <
0.0001 ) 。在在 3 个组之中的 sIL-6R 集中没有有效差量。当有 HCC 的病人根据 Okuda 的分类被划分成组时, IL-6 和 sIL-6R 水平的重要浆液增加从舞台被观察我上演 III (P <
0.02, P <
0.0005 ) 。当 HCC 和 LC 病人根据孩子呸被划分成肝硬化严厉的 3 个班时,在 HCC 病人的价值比在为各相应的班的 LC 病人的那些显著地高(P <
0.01 ).CONCLUSION:在 HCC 病人的 IL-6 浆液层次比在 LC 病人和控制的那些高,建议由肿瘤的房间的这 cytokine 的增加的生产。sIL-6R 价值在所有组是类似的,仅仅在阶段 III HCC 病人增加。这些数据建议他们与肿瘤的团而非与剩余的工作有一种更靠近的关系肝的质量。 | Soresi Maurizio Giannitrapani Lydia D'Antona Fabio Florena Ada Maria La Spada Emanuele Terranova Angela Cervello Melchiorre D'Alessandro Natale Montalto Giuseppe | 2006 | World Journal of Gastroenterology2006，12，16： | 25 |
| 2 | Botulinum toxin associated with fissurectomy and anoplasty for hypertonic chronic anal fissure: A case-control study显示文摘BACKGROUND Lateral internal sphincterotomy is still the approach of choice for the treatment of chronic anal fissure(CAF)with internal anal sphincter(IAS)hypertonia,but it is burdened by high-risk postoperative faecal incontinence(FI).Sphincter saving procedures have recently been reconsidered as treatments to overcome this risk.The most employed procedure is fissurectomy with anoplasty,eventually associated with pharmacological sphincterotomy.AIM To evaluate whether fissurectomy and anoplasty with botulinum toxin injection improves the results of fissurectomy and anoplasty alone.METHODS We conducted a case-control study involving 30 male patients affected by CAF with hypertonic IAS who underwent fissurectomy and anoplasty with V-Y cutaneous flap advancement.The patients were divided into two groups:Those in group I underwent surgery alone,and those in group II underwent surgery and a botulinum toxin injection directly into the IAS.They were followed up for at least 2 years.The goals were to achieve complete healing of the patient and to assess the FI and recurrence rate along with manometry parameters.RESULTS The intensity and duration of post-defecatory pain decreased significantly in both groups of patients starting with the first defecation,and this reduction was higher in group II.Forty days after surgery,we achieved complete wound healing in all the patients in group II but only in 80%of the patients in group I(P<0.032).We recorded 2 cases of recurrence,one in each group,and both healed with conservative therapy.We recorded one temporary and low-grade postoperative case of“de novo”FI.Manometry parameters reverted to the normal range earlier for group II patients.CONCLUSION The injection of botulinum toxin A in association with fissurectomy and anoplasty with a V-Y advancement flap improves the results of surgery alone in patients affected by CAF with IAS hypertonia. | Beatrice D'Orazio Girolamo Geraci Fausto Famà Gloria Terranova Gaetano Di Vita | 2021 | World Journal of Clinical Cases2021，9，32： | 2 |
| 3 | Estimating sample size and persistence entomogenous nematodes in sandy soils and their efficacy against the larvae of Di- aprepes abbreviatus in Florida显示文摘 | Duncan L W McCoy C W Terranova A C | 1996 | Journal of Nematolo-gy1996，28，1： | 1 |
| 4 | Autoimmune ovarian inflammation triggered by proinflammatory(Th1) T cells is compatible with normal ovarian function in mice显示文摘 | Begawan H Adams S Terranova P | 1999 | Biol Reprod1999，61，3： | 1 |
| 5 | Review:cytokine involvement in ovarian processes 显示文摘 | Terranova PF Rice VM | 1997 | Am J Reprod Immunol1997，37，1： | 1 |
| 6 | Recurrent acute rhinosinusitis:a single blind clinical study of N-acetylcysteine vs ambroxol associated to corticosteroid therapy显示文摘 | Macchi A Terranova P Castelnuovo P | | 0，，01： | 1 |
| 7 | Adeno - associated virus - delivered short hairpin - structured RNA for androgen receptor gene silencing induces tumor eradication of prostate cancer xenografts in nude mice:a preclinical study显示文摘 | Sun A Tang J Terranova PF | 2010 | Int J Cancer2010，126，3： | 1 |
| 8 | Does HE4 have a role as biomarker in the recurrence of ovarian cancer?显示文摘 | Francesco Plotti Stella Capriglione Corrado Terranova Roberto Montera Alessia Aloisi Patrizio Damiani Ludovico Muzii Giuseppe Scaletta Pierluigi Benedetti-Panici Roberto Angioli | 2012 | Tumor Biology2012，，： | 1 |
| 9 | A numerical and experimental investigation on the fatigue behavior of a steel nitrided crankshaft for high power IC engines显示文摘 | Sergio Baragetti Stefano Cavalleri Angelo Terranova | 2010 | Journal of Engineering Materials and Technology2010，132，1： | 1 |
| 10 | Adeno-associated virus-delivered short hairpin-structured RNA for androgen receptor gene silencing induces tumor eradieation of prostate cancer xenografts in nude mice: A preelinieal study 显示文摘 | Sun A Tang J Terranova PF | 2010 | Int J Cancer2010，126，3： | 1 |
| 11 | Does HE4 have a role as biomarker in the recurrence of ovarian cancer 显示文摘 | Plotti F Capriglione S Terranova C | 2012 | Tumour Biol2012，33，3： | 1 |
| 12 | Frontal sinus osteomas:the window of endonasal endoscopic approach显示文摘 | BIGNAM I M DALLAN I TERRANOVA P | 2007 | Rhinology2007，45，： | 1 |
| 13 | Periodontal regeneration:AFSCM,Assays for specific migration显示文摘 | Terranova VP Hic S Franzetti LC | 1989 | J Periodontol1989，60，8： | 1 |
| 14 | Review: cytokine involvement in ovarian processes显示文摘 | Rice V M | 1997 | Am J Report Immunol1997，37，： | 1 |
| 15 | Self-assembled carbon nanotubes grown without catalyst from nanosized carbon particles adsorbed on silicon显示文摘 | Botti S Ciardi R Terranova M L Piccirillo S | 2002 | Applied Physicals Letters2002，80，： | 1 |
| 16 | Repopulation of dentin surfaces by periodontal ligament cells and endothelial cells-Effct of basic fibroblast growth factor显示文摘 | Odziemiec C Tweden KS | 1989 | J Periodontal1989，60，6： | 1 |
| 17 | A critical review on HE4 performance in endometrial cancer: where are we now?显示文摘 | Roberto Angioli Andrea Miranda Alessia Aloisi Roberto Montera Stella Capriglione Carlo Cicco Nardone Corrado Terranova Francesco Plotti | 2014 | Tumor Biology2014，，2： | 1 |
| 18 | Neovascularization of surface demineralized dentin显示文摘 | Spadone DP Terranova VP | 1989 | J Periodontal1989，60，8： | 1 |
| 19 | Review: cytokine involvement in ovarian processes显示文摘 | Terranova PF Rice VM | 1997 | Am J Reprod Immunol1997，37，1： | 1 |
| 20 | Potential roles of tumor necrosis factor-α in follicular development, ovulation, and the life span of the corpus luteum 显示文摘 | Terranova PF | 1997 | Domes Animal Endocri1997，14，1： | 1 |
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