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| 1 | Prognosis of lymphotropic invasive micropapillary breast carcinoma analyzed by using data from the National Cancer Database显示文摘Background:Invasive micropapillary carcinoma(IMPC)is an uncommon subtype of breast cancer.Previous studies of this subtype demonstrated a higher propensity for lymph node metastases as compared with invasive ductal carci-noma(IDC).The purpose of the present study was to determine the clinical characteristics,outcomes,and propensity for lymph node metastasis of patients with IMPC of the breast recorded in the National Cancer Database(NCDB).Methods:Records of patients with IMPC diagnosed between 2004 and 2014 were retrieved from the NCDB.Log-rank test was performed to evaluate associations of clinical characteristics with overall survival(OS).Cox proportional hazards model was used to determine variables associated with OS.Results:Overall,2660 patients with IMPC met the selection criteria;the 5-year OS rate was 87.5%and 24.9%of patients had nodal involvement at presentation.Patients with≥4 positive lymph nodes had shorter OS than node-negative patients,whereas patients with 1-3 positive nodes had similar OS to node-negative patients.Age<65 years,receipt of radiotherapy,and estrogen receptor positivity were also associated with prolonged OS.The benefit of radiotherapy was limited to IMPC patients undergoing lumpectomy;there was no benefit for the patients undergoing mastectomy(regardless of nodal positivity/negativity).Conclusions:Favorable prognostic factors of IMPC patients included age<65 years,<4 positive lymph nodes,receipt of radiotherapy,and estrogen receptor positivity.The results presented herein suggest a survival benefit asso-ciated with radiotherapy in IMPC treatment,though this may be limited to the patients treated with lumpectomy. | Gary D.Lewis Yan Xing Waqar Haque Tejal Patel Mary Schwartz Albert Chen Andrew Farach Sandra S.Hatch E.Brian Butler Jenny Chang Bin S.Teh | 2019 | Cancer Communications2019，39，1： | 7 |
| 2 | 采用美国国家癌症数据库数据分析淋巴浸润性微乳头状乳腺癌的预后显示文摘背景与目的浸润性微乳头状癌(invasive micropapillary carcinoma,IMPC)是乳腺癌中一种罕见的亚型。已有研究表明,与浸润性导管癌(invasive ductal carcinoma,IDC)相比,该亚型更易发生淋巴结转移。本研究旨在明确美国国家癌症数据库(National Cancer Database,NCDB)中记录的乳腺IMPC患者的临床特征、结局和淋巴结转移倾向性。方法从NCDB中检索2004–2014年之间诊断为IMPC患者的病历,并对其进行log-rank检验以评估临床特征与总生存期(overall survival,OS)的相关性。采用Cox比例风险模型确定OS相关因素。结果本研究共纳入2660例IMPC患者。5年OS率为87.5%,24.9%患者出现淋巴结转移。阳性淋巴结数≥4的患者的OS短于阴性淋巴结的患者,而阳性淋巴结数为1–3的患者的OS与阴性淋巴结患者相似。年龄<65岁、接受放疗和雌激素受体阳性也与OS延长有关。放疗仅对接受肿块切除术的IMPC患者有效,对进行乳房切除术的患者无效(无论淋巴结阳性/阴性)。结论IMPC患者的有利预后因素包括年龄<65岁、阳性淋巴结数<4、接受放疗和雌激素受体阳性。本研究结果表明,IMPC患者的生存获益与放疗相关,但可能仅限于经肿块切除术治疗的患者。 | Gary DLewis Yan Xing Waqar Haque Tejal Patel Mary Schwartz Albert Chen Andrew Farach Sandra SHatch EBrian Butler Jenny Chang Bin S.Teh | 2020 | 癌症2020，39，2： | 2 |
| 3 | Nanocellulose,a versatile platform:From the delivery of active molecules to tissue engineering applications显示文摘Nanocellulose,a biopolymer,has received wide attention from researchers owing to its superior physicochemical properties,such as high mechanical strength,low density,biodegradability,and biocompatibility.Nanocellulose can be extracted from wide range of sources,including plants,bacteria,and algae.Depending on the extraction process and dimensions(diameter and length),they are categorized into three main types:cellulose nanocrystals(CNCs),cellulose nanofibrils(CNFs),and bacterial nanocellulose(BNC).CNCs are a highly crystalline and needle-like structure,whereas CNFs have both amorphous and crystalline regions in their network.BNC is the purest form of nanocellulose.The nanocellulose properties can be tuned by chemical functionalization,which increases its applicability in biomedical applications.This review highlights the fabrication of different surface-modified nanocellulose to deliver active molecules,such as drugs,proteins,and plasmids.Nanocellulose-mediated delivery of active molecules is profoundly affected by its topographical structure and the interaction between the loaded molecules and nanocellulose.The applications of nanocellulose and its composites in tissue engineering have been discussed.Finally,the review is concluded with further opportunities and challenges in nanocellulose-mediated delivery of active molecules. | Tejal V.Patil Dinesh K.Patel Sayan Deb Dutta Keya Ganguly Tuhin Subhra Santra Ki-Taek Lim | 2022 | Bioactive Materials2022，7，3： | 2 |
| 4 | Omeprazole improves the anti‐obesity and antidiabetic effects of exendin‐4 in db/db mice (奥美拉唑改善唾液素‐4 对 db/db 小鼠的减肥与降糖作用)*显示文摘 | Vishal Patel Amit Joharapurkar Tejal Gandhi Kirti Patel Nirav Dhanesha Samadhan Kshirsagar Vipin Dhote Jaysukh Detroja Rajesh Bahekar Mukul Jain | 2013 | Journal of Diabetes2013，，2： | 1 |
| 5 | Microfabricated drug delivery systems:From particles to pores显示文摘 | Desai Tejal A | 2003 | Advanced Drug Delivery Reviews2003，55，3： | 1 |
| 6 | Micromachined biocapsules for cell-based sensing and delivery显示文摘 | Desal Tejal A | 2004 | Advanced Drug Delivery Reviews2004，56，2： | 1 |
| 7 | 显示文摘 | Tao Sarah L Desai Tejal A | 2003 | Advanced Drug Delivery Reviews2003，55，3： | 1 |
| 8 | Characterization of micromachined silicon membranes for immunoisolation and bioseparation applications显示文摘 | Hansford Derek Ferrari Mauro | 1999 | Journal of Membrane Science1999，159，12： | 1 |
| 9 | Nanoporous microsystems for islet cell replacement显示文摘 | West Teri Cohen Michael | 2004 | Advanced Drug Delivery Reviews2004，56，11： | 1 |
| 10 | A Preliminary Study to Assess Possible Chromosomal Damage Among Users of Digital Mobile Phones显示文摘 | P. K. Gadhia Tejal Shah Amit Mistry Meonis Pithawala Dipesh Tamakuwala | 2003 | Electromagnetic Biology and Medicine (-)2003，，2： | 1 |
| 11 | 显示文摘 | Lara 1 Tejal A D | 2004 | Advanced Druy Delivery Rev lews2004，56，： | 1 |
| 12 | Overexpression of CD44: A useful independent predictor of prognosis in patients with colorectal carcinomas显示文摘 | Jyotsna M. Bhatavdekar PhD Devendra D. Patel MS Priya R. Chikhlikar MSc Trupti I. Trivedi MSc Neha M. Gosalia MSc Nandita Ghosh PhD Neelam G. Shah PhD Hemangini H. Vora PhD Tejal P. Suthar MSc | 1998 | Annals of Surgical Oncology1998，，6： | 1 |
| 13 | Patient characteristics and experiences associated with trust in specialist physicians 显示文摘 | Keating N L Tejal K Gandhi E | 2004 | Arch Intern Med2004，164，9： | 1 |
| 14 | Parallel evolution of tumour subclones mimics diversity between tumours显示文摘 | Pierre Martinez Nicolai Juul Birkbak Marco Gerlinger Nicholas McGranahan Rebecca A Burrell Andrew J Rowan Tejal Joshi Rosalie Fisher James Larkin Zoltan Szallasi Charles Swanton | 2013 | J Pathol2013，，4： | 1 |
| 15 | Decreased Staphylococcus epidermis adhesion and increased osteoblast functionality on antibiotic-loaded titania nanotubes显示文摘 | Ketul C. Popat Matthew Eltgroth Thomas J. LaTempa Craig A. Grimes Tejal A. Desai | 2007 | Biomaterials2007，，32： | 1 |
| 16 | Role of leukotrienes in NSAID induced gastric ulceration and inflammation in wistar rats显示文摘 | Maulik N Gandhi Siva Reddy Challa Pari Prasanth Tejal R Gandhi | 2012 | Asian Pacific Journal of Tropical Disease2012，，3： | 1 |
| 17 | Controlling nonspecific protein interactions in silicon biomicrosystems with nanostructured poly(ethylene glycol) films显示文摘 | Sadhana Sharma Ketul C Popat Tejal A Desai | 2002 | Langmuir2002，18，： | 1 |
| 18 | Reaction pathways in the selective oxidation of propane over a mixed metal oxide catalyst显示文摘 | Manhua Lin Tejal B Desai Frederick W Kaiser Peter D Klugherz | 2000 | Catalysis Today2000，，1： | 1 |
| 19 | Microfahricated drug delivery systems: from particles to pores 显示文摘 | Sarah LT Tejal AD | 2003 | Advanced Drug Delivery Reviews2003，55，： | 1 |
| 20 | Nanoporous anti-fouling silieon membranes for biosensor applications显示文摘 | Tejal A Desai Derek J Hansford Lara Leoni | 2000 | Biosensors and Bioelectronics2000，15，： | 1 |
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