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| 1 | Production of bacterial cellulose by Gluconacetobacter hasenii using a new bioreactor equipped with centrifugal impeller显示文摘 | Joong K P Omer S Taous K | 2007 | Korean Journal of Chemical Engineering2007，24，2： | 1 |
| 2 | Production of bacterial cellulose by Gluconacetobacter hansenii using a novel bioreactor equipped with a spin filter显示文摘 | Jae Yong Jung Taous Khan Joong Kon Park | 2007 | The Korean Journal of Chemical Engineering2007，34，7： | 1 |
| 3 | Production of bacterial cellulose in static conditions by a simple fed - batch cultivation strategy 显示文摘 | Omer Shehzad Salman Khan Taous Khan | 2009 | The Korean Journal of Chemical Engineering2009，26，6： | 1 |
| 4 | Structural studies of the glucuronic acid oligomers produced by Gluconacetobacter hansenii strain显示文摘 | Joong Kon Park Taous Khan Jae Yong Jung | 2005 | Carbohydrate Polymers2005，，4： | 1 |
| 5 | Physicochemical and mechanical characterization of bacterial cellulose produced with an excellent productivity in static conditions using a simple fed-batch cultivation strategy显示文摘 | Omer Shezad Salman Khan Taous Khan Joong Kon Park | 2010 | Carbohydrate Polymers2010，，1： | 1 |
| 6 | Production of bacterial cellulose by Gluconacetobacter hansenii using a novel bioreactor equipped with a spin filter显示文摘 | Jae Yong Jung Taous Khan Joong Kon Park | 2007 | Korean Journal of Chemical Engineering2007，24，2： | 1 |
| 7 | Effects of glucuronic acid oligomers on the production,structure and properties of bacterial cellulose显示文摘 | Mazhar Ul-Islam Jung Hwan Ha Taous Khan | 2013 | Carbohydrate Polymers2013，92，： | 1 |
| 8 | Production of bacterial cellulose by a static cultivation using the waste from beer culture broth显示文摘 | Jung Hwan Ha Omer Shehzad Salman Khan Seung Yong Lee Joon Won Park Taous Khan Joong Kon Park | 2008 | Korean Journal of Chemical Engineering2008，，4： | 1 |
| 9 | Bacterial cellulose-MMTs nanoreinforced composite films: novel wound dressing material with antibacterial properties显示文摘 | Mazhar Ul-Islam Taous Khan Waleed Ahmad Khattak Joong Kon Park | 2013 | Cellulose2013，，2： | 1 |
| 10 | Chemical Composition and Vasorelaxant and Antispasmodic Effects of Essential Oil from Rosa indica L. Petals显示文摘 | Hafiz Majid Rasheed Taous Khan Fazli Wahid Rasool Khan Abdul Jabbar Shah Micha? Tomczyk | 2015 | Evidence-Based Complementary and Alternative Medi2015，，： | 1 |
| 11 | TNF receptor I sensitizes neu- rons to erythropoietin-- and VEGF--mediated neuroprotection af- ter ischem ic and excitotoxic injury显示文摘 | Taou/'ik E Petit E Divoux D | 2008 | Proc Natl A cad Sci U S A2008，105，16： | 1 |
| 12 | Water holding md release properties of bacterial cellulose obtained by in situ mdex situ modification显示文摘 | MAZHAR U I TAOUS K JOONG K P | 2012 | Carbohydrate Polymers2012，，88： | 1 |
| 13 | Separation of phenylatanine racemates using d-phenylalanine imprinted microbeads as HPLC stationary phase 显示文摘 | Hamayun Khan Taous Khan Joong Kon Park | 2008 | Separation and Purification Technology2008，62，： | 1 |
| 14 | Removal of 2-Chlo- rophenol From Aqueous Solutionby Mg/A1 Layered Double Hy- droxide (LDH) and Modified LDH 显示文摘 | Chuang Y H Taou Y M Wang M K | 2008 | Industrial & Engineer- ing Chemistry Research2008，47，： | 1 |
| 15 | Antihypertensive efficacy of extract of Hedera helix in high salt-induced hypertensive Sprague-Dawley rats显示文摘Objective: To explore the antihypertensive effect of extracts from the leaves of Hedera helix(H. helix) on normotensive and hypertensive rats in-vivo followed by vasodilatory studies in-vitro.Methods: The crude methanolic extract was prepared and the activity directed fractionation was carried out. Spectrophotometric analysis of total phenolic and flavonoid content was also done. HPLC analysis was performed for the detection of hederacoside C. In-vivo blood pressure study was carried out in normotensive and high salt-induced hypertensive SpragueDawley rats. Isolated aortic tissues from rat and rabbit were used for in-vitro studies. The effects were recorded and analyzed through PowerL ab data acquisition system. Results: Crude extract of H. helix(1-30 mg/kg) decreased blood pressure to greater extent in high salt-induced hypertensive rats in-vivo compared to the normotensive [Max. fall(58.59±0.02) mm Hg vs.(67.53±3.07) mmH g]. The n-hexane, chloroform, ethyl acetate and aqueous fractions were also checked. These fractions were more effective in hypertensive rats. Aqueous fraction was more potent and n-hexane the least. In isolated rat aortic rings precontracted with phenylephrine, crude extract induced endothelium-dependent effect. The endothelium-dependent component of vasodilatory effect was ablated with L-NAME, and denudation of endothelium. The aqueous fraction was most potent vasodilator. In aortic rings from hypertensive rats, extract and fractions produced partial endothelium-independent effect which was not affected by pretreatment with L-NAME, indicating endothelium dysfunction in the hypertensive rats and suggesting additional vasodilatory mechanisms. In rabbit aorta, the extract and fractions also inhibited phenylephrine and high K^+-induced precontractions, and shifted Ca^(++) concentration–response curves. Conclusions: Our findings indicate that extract and fractions of H. helix are antihypertensive remedies, which is the outcome of vasodilatory effect. This vasodilatory effect is mediated through nitric oxide and Ca^(++) antagonism. | Umme Salma Taous Khan Abdul Jabbar Shah | 2018 | Asian Pacific Journal of Tropical Medicine2018，11，8： | 0 |
| 16 | RIPK1 inhibition contributes to lysosomal membrane stabilization in ischemic astrocytes via a lysosomal Hsp70.1B-dependent mechanism显示文摘Receptor-interacting protein kinase 1(RIPK1)contributes to necroptosis.Our previous study showed that pharmacological or genetic inhibition of RIPK1 protects against ischemic stroke-induced astrocyte injury.In this study,we investigated the molecular mechanisms underlying RIPK1-mediated astrocyte injury in vitro and in vivo.Primary cultured astrocytes were transfected with lentiviruses and then subjected to oxygen and glucose deprivation(OGD).In a rat model of permanent middle cerebral artery occlusion(pMCAO),lentiviruses carrying shRNA targeting RIPK1 or shRNA targeting heat shock protein 70.1B(Hsp70.1B)were injected into the lateral ventricles 5 days before pMCAO was established.We showed that RIPK1 knockdown protected against OGD-induced astrocyte damage,blocked the OGD-mediated increase in lysosomal membrane permeability in astrocytes,and inhibited the pMCAO-induced increase in astrocyte lysosome numbers in the ischemic cerebral cortex;these results suggested that RIPK1 contributed to the lysosomal injury in ischemic astrocytes.We revealed that RIPK1 knockdown upregulated the protein levels of Hsp70.1B and increased the colocalization of Lamp1 and Hsp70.1B in ischemic astrocytes.Hsp70.1B knockdown exacerbated pMCAO-induced brain injury,decreased lysosomal membrane integrity and blocked the protective effects of the RIPK1-specific inhibitor necrostatin-1 on lysosomal membranes.On the other hand,RIPK1 knockdown further exacerbated the pMCAO-or OGD-induced decreases in the levels of Hsp90 and the binding of Hsp90 to heat shock transcription factor-1(Hsf1)in the cytoplasm,and RIPK1 knockdown promoted the nuclear translocation of Hsf1 in ischemic astrocytes,resulting in increased Hsp70.1B mRNA expression.These results suggest that inhibition of RIPK1 protects ischemic astrocytes by stabilizing lysosomal membranes via the upregulation of lysosomal Hsp70.1B;the mechanism underlying these effects involves decreased Hsp90 protein levels,increased Hsf1 nuclear translocation and increased Hsp70.1B mRNA expression. | Hua-ping Du Yi Guo Yong-ming Zhu De-fei Gao Bo Lin Yuan Liu Yuan Xu Ali Said Taous Khan Li-jun Liu Jian-jun Zhu Yong Ni Hui-ling Zhang | 2023 | Acta Pharmacologica Sinica2023，44，8： | 0 |
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