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| 1 | role of the normal gut microbiota显示文摘Relation between the gut microbiota and human health is being increasingly recognised. It is now well established that a healthy gut flora is largely responsible for overall health of the host. The normal human gut microbiota comprises of two major phyla, namely Bacteroidetes and Firmicutes. Though the gut microbiota in an infant appears haphazard, it starts resembling the adult flora by the age of 3 years. Nevertheless, there exist temporal and spatial variations in the microbial distribution from esophagus to the rectum all along the individual's life span. Developments in genome sequencing technologies and bioinformatics have now enabled scientists to study these microorganisms and their function and microbehost interactions in an elaborate manner both in health and disease. The normal gut microbiota imparts specific function in host nutrient metabolism, xenobiotic and drug metabolism, maintenance of structural integrity of the gut mucosal barrier, immunomodulation, and protection against pathogens. Several factors play a role in shaping the normal gut microbiota. They include(1) the mode of delivery(vaginal or caesarean);(2) diet during infancy(breast milk or formula feeds) and adulthood(vegan based or meat based); and(3) use of antibiotics or antibiotic like molecules that are derived from the environment or the gut commensal community. A major concern of antibiotic use is the long-term alteration of the normal healthy gut microbiota and horizontal transfer of resistance genes that could result in reservoir of organisms with a multidrug resistant gene pool. | Sai Manasa Jandhyala Rupjyoti Talukdar Chivkula Subramanyam Harish Vuyyuru Mitnala Sasikala D Nageshwar Reddy | 2015 | World Journal of Gastroenterology2015，21，29： | 187 |
| 2 | Pancreatic stellate cell: Pandora's box for pancreatic disease biology显示文摘Pancreatic stellate cells(PSCs) were identified in the early 1980 s, but received much attention after 1998 when the methods to isolate and culture them from murine and human sources were developed. PSCs contribute to a small proportion of all pancreatic cells under physiological condition, but are essential for maintaining the normal pancreatic architecture. Quiescent PSCs are characterized by the presence of vitamin A laden lipid droplets. Upon PSC activation, these perinuclear lipid droplets disappear from the cytosol, attain a myofibroblast like phenotype and expresses the activation marker, alpha smooth muscle actin. PSCs maintain their activated phenotype via an autocrine loop involving different cytokines and contribute to progressive fibrosis in chronic pancreatitis(CP) and pancreatic ductal adenocarcinoma(PDAC). Several pathways(e.g., JAK-STAT, Smad, Wnt signaling, Hedgehog etc.), transcription factors and mi RNAs have been implicated in the inflammatory and profibrogenic function of PSCs. The role of PSCs goes much beyond fibrosis/desmoplasia in PDAC. It is now shown that PSCs are involved in significant crosstalk between the pancreatic cancer cells and the cancer stroma. These interactions result in tumour progression, metastasis, tumour hypoxia, immune evasion and drug resistance. This is the rationale for therapeutic preclinical and clinical trials that have targeted PSCs and the cancer stroma. | Ratnakar R Bynigeri Aparna Jakkampudi Ramaiah Jangala Chivukula Subramanyam Mitnala Sasikala G Venkat Rao D Nageshwar Reddy Rupjyoti Talukdar | 2017 | World Journal of Gastroenterology2017，23，3： | 25 |
| 3 | How Social Influence Affects Consumption Trends in Emerging Markets: An Empirical Investigation of the Con- sumption Convergence Hypothesis 显示文摘 | DHOLAKIA U M TALUKDAR D | 2004 | Psychology and Marketing2004，21，10： | 1 |
| 4 | Does the private sector help or hurt the environment? Evidence from carbon dioxide pollution in developing countries 显示文摘 | TALUKDAR D MEISNER C M | 2001 | World Development2001，，5： | 1 |
| 5 | Does the Private Sector Help or Hurt the Environment? Evidence from Carbon Dioxide Pollution in Developing Countries 显示文摘 | Talukdar D Meisner C M | 2001 | World Development2001，29，5： | 1 |
| 6 | Characterization and Screening of Bacteria from Rhizosphere of Rice Grown in Acidic Soils of Assam显示文摘 | Thakuria D Talukdar N C Goswami C | 2004 | Current Science2004，86，7： | 1 |
| 7 | Characterization and screening of bacteria from rhizosphere of rice grown in acidic soils of assam 显示文摘 | Thakuria D Talukdar N C Goswami C | 2004 | Current Science2004，86，7： | 1 |
| 8 | Increased macrophage migration into adipose tissue in obese miee显示文摘 | Oh D Y Morinaga H Talukdar S | 2012 | Diabetes2012，61，2： | 1 |
| 9 | Critical evaluation of toxic versus beneficial effects of methylglyoxal显示文摘 | Talukdar D Chaudhuri BS Ray M | 2009 | Biochemistry (Mosc)2009，74，10： | 1 |
| 10 | Charac- terization and screening of bacteria from rhizosphere orice grown in acidic soils of Assam显示文摘 | Thakuria D Talukdar N C Goswami C | 2004 | Current Science2004，86，7： | 1 |
| 11 | Evaluation of rice- legume-rice cropping system on grain yield, nutrient uptake, nitro- gen fixation, and chemical, physical, and biological properties of soil显示文摘 | Thakuria D T Talukdar N Goswami C | 2008 | Biology and Fertility of Soils2008，45，3： | 1 |
| 12 | Characterization and screening of bacteria from rhizosphere of rice grown in acidic soils of Assam显示文摘 | Thakuria D Talukdar N C Goswami C | 2004 | Current Science2004，86，7： | 1 |
| 13 | A model of consumer choice of the internet as an information source 显示文摘 | Ratchford B Talukdar D Lee M | 2001 | International Journal of Electronic Commerce2001，，3： | 1 |
| 14 | Distributed model predictive control显示文摘 | Jia D Krogh B H Talukdar S | 2002 | IEEE Control Systems Magazine2002，22，1： | 1 |
| 15 | Relationship between product groups' price perceptions, shopper's basket Size, and grocery store's overall price image 显示文摘 | Desai K K Talukdar D | 2003 | Psychology & Marketing2003，20，10： | 1 |
| 16 | GPR120 is an x-3 fatty acid receptor mediating potent anti-inflammatory and insulin sensitizing effects显示文摘 | Oh D Y Talukdar S Bae E J | 2010 | Cell2010，142，： | 1 |
| 17 | Consumer information search revisited: Theory and empirical analysis 显示文摘 | Moorthy S Ratchford B T Talukdar D | 1997 | Journal of Consumer Research1997，23，4： | 1 |
| 18 | GPR120 is an ome- ga-3 fatty acid receptor mediating potent anti-inflammatory and insulin- sensitizing effects 显示文摘 | Oh D Y Talukdar S Bae E J | 2010 | Cell2010，142，5： | 1 |
| 19 | Investigating new product diffusion across products and countries 显示文摘 | Talukdar D Sudhir K Andrew A | 2002 | Marketing Science2002，21，1： | 1 |
| 20 | Does the P1995,Rivate Sector Help or Hurt the Environment?Evidence form Carbon Dioxide Pollution in Developing Countries 显示文摘 | Talukdar D Meisner M C | 2001 | World Development2001，29，5： | 1 |
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