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| 1 | Impact of referral pattern and timing of repair on surgical outcome after reconstruction of post-cholecystectomy bile duct injury:A multicenter study显示文摘Background:Bile duct injury(BDI)after cholecystectomy remains a significant surgical challenge.No guideline exists to guide the timing of repair,while few studies compare early versus late repair BDI.This study aimed to analyze the outcomes in patients undergoing immediate,intermediate,and delayed repair of BDI.Methods:We retrospectively analyzed 412 patients with BDI from March 2015 to January 2020.The patients were divided into three groups based on the time of BDI reconstruction.Group 1 underwent an immediate reconstruction(within the first 72 hours post-cholecystectomy,n=156);group 2 underwent an intermediate reconstruction(from 4 days to 6 weeks post-cholecystectomy,n=75),and group 3 underwent delayed reconstruction(after 6 weeks post-cholecystectomy,n=181).Results:Patients in group 2 had significantly more early complications including anastomotic leakage and intra-abdominal collection and late complications including anastomotic stricture and secondary liver cirrhosis compared with groups 1 and 3.Favorable outcome was observed in 111(71.2%)patients in group 1,31(41.3%)patients in group 2,and 157(86.7%)patients in group 3(P=0.0001).Multivariate analysis identified that complete ligation of the bile duct,level E1 BDI and the use of external stent were independent factors of favorable outcome in group 1,the use of external stent was an independent factor of favorable outcome in group 2,and level E4 BDI was an independent factor of unfavorable outcome in group 3.Transected BDI and level E4 BDI were independent factors of unfavorable outcome.Conclusions:Favorable outcomes were more frequently observed in the immediate and delayed reconstruction of post-cholecystectomy BDI.Complete ligation of the bile duct,level E1 BDI and the use of external stent were independent factors of a favorable outcome. | Ayman El Nakeeb Ahmad Sultan Helmy Ezzat Mohamed Attia Mohamed Abd ElWahab Taha Kayed Ayman Hassanen Ahmad AlMalki Ahmed Alqarni Mohammed M Mohammed | 2021 | Hepatobiliary & Pancreatic Diseases International2021，20，1： | 4 |
| 2 | Profiling cellular bioenergetics, glutathione levels, and caspase activities in stomach biopsies of patients with upper gastrointestinal symptoms显示文摘AIM: To measure biochemical parameters in stomach biopsies and test their suitability as diagnostic biomarkers for gastritis and precancerous lesions.METHODS: Biopsies were obtained from the stomachs of two groups of patients(n = 40) undergoing fiberoptic endoscopy due to upper gastrointestinal symptoms. In the first group(n = 17), only the corpus region was examined. Biopsies were processed for microscopic examination and measurement of mitochondrial O2 consumption(cellular respiration), cellular adenosine triphosphate(ATP), glutathione(GSH), and caspase activity. In the second group of patients(n = 23), both corpus and antral regions were studied. Some biopsies were processed for microscopic examination, while the others were used for measurements of cellular respiration and GSH level.RESULTS: Microscopic examinations of gastric corpus biopsies from 17 patients revealed normal mucosae in 8 patients, superficial gastritis in 7 patients, and chronic atrophic gastritis in 1 patient. In patients with normal histology, the rate(mean ± SD) of cellular respiration was 0.17 ± 0.02 μmol/L O2 min-1 mg-1, ATP content was 487 ± 493 pmol/mg, and GSH was 469 ± 98 pmol/mg. Caspase activity was detected in 3 out of 8 specimens. The values of ATP and caspase activity were highly variable. The presence of superficial gastritis had insignificant effects on the measured biomarkers. In the patient with atrophic gastritis, cellular respiration was high andATP was relatively low, suggesting uncoupling oxidative phosphorylation. In the second cohort of patients, the examined biopsies showed either normal or superficial gastritis. The rate of cellular respiration(O2. μmol/L min-1 mg-1) was slightly higher in the corpus than the antrum(0.18 ± 0.05 vs 0.15 ± 0.04, P = 0.019). The value of GSH was about the same in both tissues(310 ± 135 vs 322 ± 155, P = 0.692).CONCLUSION: The corpus mucosa was metabolically more active than the antrum tissue. The data in this study will help in understanding the pathophysiology of gastric mucosa. | Ali S Alfazari Bayan Al-Dabbagh Wafa Al-Dhaheri Mazen S Taha Ahmad A Chebli Eva M Fontagnier Zaher Koutoubi Jose Kochiyi Sherif M Karam Abdul-Kader Souid | 2015 | World Journal of Gastroenterology2015，21，2： | 2 |
| 3 | First United Arab Emirates consensus on diagnosis and management of inflammatory bowel diseases:A 2020 Delphi consensus显示文摘Ulcerative colitis and Crohn’s disease are the main entities of inflammatory bowel disease characterized by chronic remittent inflammation of the gastrointestinal tract.The incidence and prevalence are on the rise worldwide,and the heterogeneity between patients and within individuals over time is striking.The progressive advance in our understanding of the etiopathogenesis coupled with an unprecedented increase in therapeutic options have changed the management towards evidence-based interventions by clinicians with patients.This guideline was stimulated and supported by the Emirates Gastroenterology and Hepatology Society following a systematic review and a Delphi consensus process that provided evidence-and expert opinion-based recommendations.Comprehensive up-to-date guidance is provided regarding diagnosis,evaluation of disease severity,appropriate and timely use of different investigations,choice of appropriate therapy for induction and remission phase according to disease severity,and management of main complications. | Maryam Alkhatry Ahmad Al-Rifai Vito Annese Filippos Georgopoulos Ahmad N Jazzar Ahmed M Khassouan Zaher Koutoubi Rahul Nathwani Mazen S Taha Jimmy K Limdi | 2020 | World Journal of Gastroenterology2020，26，43： | 2 |
| 4 | Hyperbaric oxygen in the treatment of elevated intracranial pressure after head injury, Pediatr显示文摘 | Brown J A PREUL M C TAHA A | 1988 | Neurosci1988，14，： | 1 |
| 5 | Cool surface and shade trees to reduce energy use and improve air quality in urban areas显示文摘 | Akbari H Pomerantz M Taha H | 2001 | Solar Energy2001，70，3： | 1 |
| 6 | Production and survival of tillers of wheat and their contribution to yield 显示文摘 | Ishag H M Taha M B | 1974 | Journal of Agricultural Science1974，83，7： | 1 |
| 7 | Structure development in solidified alloys 显示文摘 | Taha M A Mahallawy N A Abdel-Rehim M | 1983 | Metall1983，37，8： | 1 |
| 8 | Electrochemical behavior of Sn - Ni nanostructured compound in alkaline media and the effect of halide ions 显示文摘 | Refaey S A M Taha F A Hasanin T H | 2004 | Applied Surface Science2004，227，： | 1 |
| 9 | Gastritis induced by Helicobacter pylori infection in experimental rats显示文摘 | ELSEWEIDY M M TAHA M M YOUNIS N N | 2010 | Dig Dis Sci2010，55，10： | 1 |
| 10 | Corrosionand Inhibition of Stainless Steel Pitting Corrosion in Alka- line Medium and the Effect of C1- and Br- Anions 显示文摘 | REFAEY S A M TAHA F EL-MALAK A M A | 2005 | Ap- plied Surface Science2005，242，12： | 1 |
| 11 | Passivation and pitting corrosion of nanostructured Sn-Ni alloy in NaCl solutions显示文摘 | Refaey S A M Taha F A Hasanin T H | 2006 | Electrochimica Acta2006，51，： | 1 |
| 12 | Availability of barley straw application on oil spill clean up 显示文摘 | HUSSEIEN M AMER A A EL-MAGHRABY A TAHA N A | 2009 | International Journal of Environmental Science and Technology2009，6，1： | 1 |
| 13 | Prediction of safety factor for slope designed with various limit equilibrium methods显示文摘 | Mohamed T Kasa A Taha M R | 2011 | Key Engineering Materials2011，，： | 1 |
| 14 | Oesophagitis and bile reflux gastritis—clinical and histological assessments显示文摘 | A.S Taha M Balsitis W.J Angerson C.G Morran | 2003 | Digestive and Liver Disease2003，，10： | 1 |
| 15 | Chemo-rheological study of a dicymmte ester for the simulation of the resin transfer molding process 显示文摘 | Maazouz A Texier C Taha M | 1998 | Composites Science and Technology1998，58，5： | 1 |
| 16 | Haloperidol ondansetron for the prevention of postoperative nausea and vomiting following gynaecological surgery 显示文摘 | Aouad M T Siddik-Sayyid S M Taha S K | 2007 | Eur J Anaesthe-siol2007，24，2： | 1 |
| 17 | Pre-oxygenation:comparison of maximal breathing and tidal volume breathing techniques显示文摘 | BARAKA A S TAHA S K AOUAD M T | 1999 | Anesthesiology1999，91，3： | 1 |
| 18 | Chemo-rheological study of a dicyanate ester for the simulation of the resin transfer molding process显示文摘 | Maazouz A Texier C Taha M Alglave H | 1998 | Composites Science and Technology1998，58，： | 1 |
| 19 | Limiting shear creep of epoxy adhesive at the FRP-concrete interface using muhi- walled carbon nanotubes显示文摘 | Soliman E Kandil U F Taha M R | 2012 | Intemational Journal of Adhesion and Adhesives2012，33，： | 1 |
| 20 | Factors affecting shoot otganogenesia in leaf disc culture of African violet显示文摘 | DAUD N TAHA R M | 2008 | Pakistan Journal of Biological Sci ences2008，11，7： | 1 |
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